デザインのスキル

Designs covalent inhibitors and warheads targeting cysteine (most common, 98% of covalent drugs), lysine, serine, threonine, tyrosine, and aspartate residues, with explicit handling of warhead reactivity (acrylamide, chloroacetamide, vinyl sulfone, sulfonyl fluoride, fluorosulfate, aldehyde, boronate, nitrile), reversibility (kinact/Ki, t_residence), glutathione (GSH) stability, intrinsic reactivity assays, and covalent docking (DOCKovalent, GOLD, HCovDock). Use when designing covalent inhibitors for targeted covalent inhibition (TCI), KRAS G12C-style approaches, or rationalizing covalent SAR.

日本語の概要は準備中です。原文の説明を表示しています。

Predicts whether a DNA variant alters mRNA splicing using sequence-based deep-learning tools — SpliceAI (10kb context dilated CNN, clinical default), Pangolin (multi-tissue), MMSplice (modular per-region CNN with calibrated ΔPSI), SpliceTransformer/TrASPr (tissue-aware transformers), SpliceVault (empirical 300K-RNA lookup of likely mis-splicing outcomes), CADD-Splice (composite score). Applies the ClinGen SVI 2023 framework for ACMG/AMP variant interpretation (PVS1, PP3, BP4 evidence codes), HGVS splicing nomenclature (c.123+1G>A, c.123-3T>G, r.spl?), extended-window scoring for deep-intronic pseudoexons, tissue-specific predictions, branchpoint variant detection (BPHunter, LaBranchoR), and splice-switching ASO design. Use when interpreting splice impact of clinical variants, prioritizing VUS, identifying deep-intronic pathogenic variants, or designing ASOs.

日本語の概要は準備中です。原文の説明を表示しています。

Run the advanced iterative workflow — Wayfinding AST discovery, Relentless Grilling, contract and spec design, TDD, council review, and docs.

日本語の概要は準備中です。原文の説明を表示しています。

Design, implement, and review web interface layout, component states, feedback, and motion within the current CodeConductor workflow. Use for concrete web UI work or requested UI audits, not backend-only tasks or native mobile apps.

日本語の概要は準備中です。原文の説明を表示しています。

Design and coordinate multi-agent systems where specialized agents work together to solve complex problems. Covers agent communication, task delegation, workflow orchestration, and result aggregation. Use when building coordinated agent teams, complex workflows, or systems requiring specialized expertise across domains.

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Provides dependency injection patterns for Spring Boot projects, including constructor-first design, optional collaborator handling, bean selection, and wiring validation. Use when creating services and configurations, replacing field injection, or troubleshooting ambiguous or fragile Spring wiring.

日本語の概要は準備中です。原文の説明を表示しています。

Provides expert knowledge for building modern native Android apps using Kotlin, Jetpack Compose, Material Design 3, MVI architecture, Hilt dependency injection, and Media3/ExoPlayer.

日本語の概要は準備中です。原文の説明を表示しています。

Design, implement, review, and audit Android Jetpack Compose UI/UX for phone interfaces. Use when a request concerns concrete Compose layout, components, interaction, accessibility, or visual behavior. Do not activate for framework or dependency presence alone; non-UI Android work is excluded.

日本語の概要は準備中です。原文の説明を表示しています。

Use when working with domain models, aggregates, value objects, domain events, or repositories in a DDD-style project. Ensures rich domain model over anemic CRUD.

日本語の概要は準備中です。原文の説明を表示しています。

Diagnoses and fixes UI performance across loading speed, rendering, animations, images, and bundle size. Use when the user mentions slow, laggy, janky, performance, bundle size, load time, or wants a faster, smoother experience.

日本語の概要は準備中です。原文の説明を表示しています。

Extract and consolidate reusable components, design tokens, and patterns into your design system. Identifies opportunities for systematic reuse and enriches your component library. Use when the user asks to create components, refactor repeated UI patterns, build a design system, or extract tokens.

日本語の概要は準備中です。原文の説明を表示しています。

Design and generate Convex database schemas with proper validation, indexes, and relationships. Use when creating schema.ts or modifying table definitions.

日本語の概要は準備中です。原文の説明を表示しています。

Improves typography by fixing font choices, hierarchy, sizing, weight, and readability so text feels intentional. Use when the user mentions fonts, type, readability, text hierarchy, sizing looks off, or wants more polished, intentional typography.

日本語の概要は準備中です。原文の説明を表示しています。

Tones down visually aggressive or overstimulating designs, reducing intensity while preserving quality. Use when the user mentions too bold, too loud, overwhelming, aggressive, garish, or wants a calmer, more refined aesthetic.

日本語の概要は準備中です。原文の説明を表示しています。

Strip designs to their essence by removing unnecessary complexity. Great design is simple, powerful, and clean. Use when the user asks to simplify, declutter, reduce noise, remove elements, or make a UI cleaner and more focused.

日本語の概要は準備中です。原文の説明を表示しています。

Create distinctive, production-grade frontend interfaces with high design quality. Generates creative, polished code that avoids generic AI aesthetics. Use when the user asks to build web components, pages, artifacts, posters, or applications, or when any design skill requires project context.

日本語の概要は準備中です。原文の説明を表示しています。

Add strategic color to features that are too monochromatic or lack visual interest, making interfaces more engaging and expressive. Use when the user mentions the design looking gray, dull, lacking warmth, needing more color, or wanting a more vibrant or expressive palette.

日本語の概要は準備中です。原文の説明を表示しています。

Amplify safe or boring designs to make them more visually interesting and stimulating. Increases impact while maintaining usability. Use when the user says the design looks bland, generic, too safe, lacks personality, or wants more visual impact and character.

日本語の概要は準備中です。原文の説明を表示しています。

Agent Ready project design context for navigation, docs links, and interface tone. Use when building or reviewing UI in this repo so patterns match the documented product feel.

日本語の概要は準備中です。原文の説明を表示しています。

Adapt designs to work across different screen sizes, devices, contexts, or platforms. Implements breakpoints, fluid layouts, and touch targets. Use when the user mentions responsive design, mobile layouts, breakpoints, viewport adaptation, or cross-device compatibility.

日本語の概要は準備中です。原文の説明を表示しています。

One-time setup that gathers design context for your project and saves it to your AI config file. Run once to establish persistent design guidelines.

日本語の概要は準備中です。原文の説明を表示しています。

Full-stack Convex development guidelines covering React, Vite, TypeScript, mutations, auth, design system, and documentation practices. Use when building features, writing Convex functions, or making code changes in this project.

日本語の概要は準備中です。原文の説明を表示しています。

Improve unclear UX copy, error messages, microcopy, labels, and instructions to make interfaces easier to understand. Use when the user mentions confusing text, unclear labels, bad error messages, hard-to-follow instructions, or wanting better UX writing.

日本語の概要は準備中です。原文の説明を表示しています。

Designs and improves onboarding flows, empty states, and first-run experiences to help users reach value quickly. Use when the user mentions onboarding, first-time users, empty states, activation, getting started, or new user flows.

日本語の概要は準備中です。原文の説明を表示しています。