Coding standards, frameworks, refactoring, and code review (16.4K skills)
Use when working with Crates Io — crates.io Rust package registry management. Covers crate publishing, version management, dependency resolution, feature flags, build configurations, and crate metadata analysis. Use when managing Rust crates, publishing to crates.io, analyzing dependency trees, or configuring feature flags.
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Use when working with Devcycle — devCycle feature flag management, targeting rules, environments, variable management, and usage metrics. Covers feature creation, variation configuration, targeting rules, audience segments, and API usage tracking. Use when managing feature flags, configuring targeting rules, reviewing variable usage, or analyzing feature adoption in DevCycle.
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Use when working with Cargo — cargo Rust build and package management. Covers build configuration, workspace management, feature flags, build profiles, cross-compilation, and build script analysis. Use when managing Cargo workspaces, configuring build profiles, debugging compilation issues, or optimizing build performance.
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Use when working with Bazel — bazel build system management. Covers BUILD file analysis, target querying, dependency graphs, remote execution, caching configuration, and build performance profiling. Use when managing Bazel workspaces, debugging build failures, querying targets, or optimizing build performance.
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Use when working with Anthropic Api — anthropic API platform management covering models, usage tracking, rate limits, and message analytics. Use when monitoring API usage and costs, analyzing model request patterns, reviewing rate limit health, or troubleshooting Anthropic Claude API issues.
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Use when working with Ambassador — ambassador (Emissary-Ingress) API gateway management covering mappings, hosts, TLS contexts, authentication filters, rate limiting, and Envoy proxy configuration. Use when managing Ambassador/Emissary-Ingress routing, configuring API gateway mappings, debugging routing issues, setting up TLS termination, or analyzing gateway performance.
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REQUIRED --repo flag for all commands, helper functions for code review comments, suggestion block syntax rules
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REQUIRED helper functions (never raw curl), workspace/repo_slug patterns, suggestion block syntax for code review
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AiZynthFinder retrosynthetic route planning (CASP) from AstraZeneca Molecular AI. Monte Carlo tree search guided by a template-based neural expansion policy recursively disconnects a target SMILES until precursors are found in a purchasable stock. Covers config.yml (v4 format), aizynthcli batch screening, the AiZynthFinder/AiZynthExpander Python API, one-step disconnections, custom stocks via smiles2stock, scorers, Retro*/breadth-first/DFPN search alternatives, and reading output.json.gz / trees.json. Use for synthesis route planning, synthesizability screening, and building-block/precursor search. For reaction barriers use neb-irc-activation-energy; for 2D reaction scheme drawing use rdkit-chemdraw-cdxml.
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Patterns and architectures for autonomous Claude Code loops — from simple sequential pipelines to RFC-driven multi-agent DAG systems.
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Access AlphaFold DB's 200M+ predicted structures by UniProt ID. Download PDB/mmCIF, analyze pLDDT/PAE, bulk-fetch proteomes via Google Cloud. For experimental structures use PDB; for prediction use ColabFold or ESMFold.
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Access AlphaFold's 200M+ AI-predicted protein structures. Retrieve structures by UniProt ID, download PDB/mmCIF files, analyze confidence metrics (pLDDT, PAE), for drug discovery and structural biology.
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Analyzes genetic variant effects on gene expression (RNA-seq), chromatin accessibility (DNASE), histone marks (ChIP), and transcription factors using the AlphaGenome API. Use when the user asks about non-coding variant effects, pathogenicity, clinical significance, disease associations, functional effects, gene expression changes, splicing disruption, or regulatory effects in promoters and enhancers. Also use for resolving biological terms to tissue/cell-type ontologies (UBERON/CL) or analyzing variants in chr:pos:ref>alt format.
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Migrate from AngularJS to Angular using hybrid mode, incremental component rewriting, and dependency injection updates. Use when upgrading AngularJS applications, planning framework migrations, or modernizing legacy Angular code.
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Master Python asyncio, concurrent programming, and async/await patterns for high-performance applications. Use when building async APIs, concurrent systems, or I/O-bound applications requiring non-blocking operations.
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Search and retrieve preprints from arXiv via the Atom API. Use this skill when searching for papers in physics, mathematics, computer science, quantitative biology, quantitative finance, statistics, electrical engineering, or economics by keywords, authors, arXiv IDs, date ranges, or categories.
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Creating algorithmic art using p5.js with seeded randomness and interactive parameter exploration. Use this when users request creating art using code, generative art, algorithmic art, flow fields, or particle systems. Create original algorithmic art rather than copying existing artists' work to avoid copyright violations.
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Query ARCHS4 REST API for uniformly processed RNA-seq expression, tissue patterns, co-expression across 1M+ human/mouse samples. Retrieve z-scores, co-expressed genes, samples by metadata, HDF5 matrices. For variant population genetics use gnomad-database; for pathway enrichment use gget-genomic-databases (Enrichr).
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Use after generating code, after accepting AI suggestions, or when reviewing AI-written modules. Also use when code works but feels brittle, when error handling seems thin, when orphaned resources or missing cleanup are suspected, or when the agent claims done but hidden debt may exist. Catches the specific failure patterns AI agents produce that humans would not.
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Retrieve and analyze AlphaFold predicted structures for a protein. Use when the user provides a specific UniProt Accession ID and wants structural confidence metrics (pLDDT), domain boundary analysis, or disorder assessment. Do not use if the user only has a protein name, gene name, or amino acid sequence — ask for a UniProt ID first.
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Eliminates AI-generated writing patterns that erode reader trust. Use when writing or editing articles, docs, or press releases.
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API hardening for Express, FastAPI, and serverless. Use for rate limiting, CORS, input validation, API keys, or OWASP API Top 10.
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Vite 8.0.10 build tooling — HMR, fast builds, plugins, and optimized production assets. Use when configuring Vite, setting up React/Vue projects with Vite, or optimizing frontend build performance.
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Create isolated git worktrees with smart directory selection and safety verification
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