chembl-database
FreeQuery ChEMBL bioactivity database for drug-like molecules
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Query ChEMBL bioactivity database for drug-like molecules
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Quantum circuit design and simulation using Google Cirq
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Manage, format, and organize scientific citations and bibliographies
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Evidence-based clinical decision support and diagnostic reasoning
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Query AlphaFold protein structure predictions database
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Query BindingDB for protein-ligand binding affinity data
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Access and analyze the CZ CELLxGENE Census single-cell data
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Implements advanced TypeScript type systems with custom type guards, utility types, branded types, discriminated unions, and full-stack type safety with tRPC.
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Implements infrastructure as code with Terraform across AWS, Azure, or GCP including module development, state management, provider configuration, and multi-environment workflows.
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Defines service level objectives, creates error budget policies, designs incident response procedures, develops capacity models, and produces monitoring configurations.
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Builds Vue 3 components with Composition API, configures Nuxt 3 SSR/SSG, sets up Pinia stores, scaffolds Quasar/Capacitor mobile apps, and implements PWA features.
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Writes Spark jobs, debugs performance issues, configures cluster settings for distributed data processing, DataFrame transformations, and structured streaming analytics.
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Builds .NET 8 applications with minimal APIs, clean architecture, cloud-native microservices, Entity Framework Core, CQRS with MediatR, and AOT compilation.
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Builds Django web applications and REST APIs with Django REST Framework, creates models with proper indexes, optimizes ORM queries, and configures JWT authentication.
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Builds Next.js 14+ applications with App Router, server components, server actions, middleware, streaming SSR, and Vercel deployment.
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Identifies security vulnerabilities, generates structured audit reports with severity ratings, and provides actionable remediation guidance for SAST, DevSecOps, and compliance.
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Reverse-engineers specifications from existing codebases, maps code dependencies, generates API documentation from source, and identifies undocumented business logic.
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Creates Vue 3 components with vanilla JS composables, configures Vite projects, and sets up routing and state management using JavaScript only with JSDoc typing.
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Challenges ideas, plans, decisions, and proposals using structured critical reasoning as devil's advocate, pre-mortem, red team, or evidence audit.
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Provides idiomatic Kotlin patterns including coroutine concurrency, Flow streams, multiplatform architecture, Compose UI, Ktor servers, and type-safe DSL design.
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Generates test files, creates mocking strategies, analyzes code coverage, designs test architectures, and produces test plans across functional, performance, and security testing.
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Optimizes SQL queries, designs database schemas, troubleshoots performance with window functions, CTEs, indexing strategies, and query plan analysis across database dialects.
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Generates Spring Boot 3.x configurations, creates REST controllers, implements Spring Security 6, sets up Spring Data JPA, and configures reactive WebFlux endpoints.
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Builds Shopify themes, develops custom apps with OAuth and webhooks, implements Storefront API integrations, and creates checkout UI extensions and Shopify Functions.
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