Paperclip

Access Federal Reserve Economic Data (FRED) time series

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Access Google Data Commons public datasets and statistics

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Geospatial data analysis and visualization with GeoPandas

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Query GWAS Catalog for genome-wide association study results

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Query NCBI Gene Expression Omnibus for transcriptomics datasets

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Restricts file edits to a specified directory. Pre-tool hooks intercept Edit and Write operations. Trailing-slash matching prevents partial path collisions.

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Manage, format, and organize scientific citations and bibliographies

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Evidence-based clinical decision support and diagnostic reasoning

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Time series analysis and temporal pattern detection for scientific data

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One-time deployment configuration. Detects platform, gathers URLs and health checks, persists to CLAUDE.md for future land-and-deploy runs.

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Weekly engineering retrospective. Analyzes commit history, work patterns, and code quality metrics. Per-person breakdowns with praise and growth areas. Modes: default 7d, 24h, 14d, 30d, compare, global cross-project. Shipping streaks and tweetable summary.

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Infrastructure-first security audit across 14 phases: attack surface mapping, secrets archaeology (git history), supply chain analysis, CI/CD pipeline security, LLM/AI threat detection, OWASP Top 10, STRIDE threat modeling. Confidence gates, exploit scenarios, parallel verification, trend tracking. Read-only.

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Query AlphaFold protein structure predictions database

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Query BindingDB for protein-ligand binding affinity data

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Query cBioPortal for cancer genomics data exploration

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Warns before destructive commands (rm -rf, DROP TABLE, force-push, git reset --hard, kubectl delete, docker force-rm). Session-scoped. Exceptions for common temp dirs (node_modules, .next, __pycache__).

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Quantum circuit design and simulation using Google Cirq

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Merge PR, wait for deploy, verify production health. 10-step workflow: pre-flight, CI check, readiness gate, merge (respects merge queue), detect platform, wait for deploy, canary verification, revert option, deploy report. Auto-detects Fly, Render, Vercel, Netlify, Heroku, GitHub Actions.

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Annotated data matrix operations for single-cell genomics using AnnData

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Astronomical computations, coordinate transforms, and celestial data analysis

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Query BRENDA enzyme information and kinetics database

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Combines careful + freeze. Dual protection: destructive command warnings plus edit boundary enforcement.

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Integration with Benchling laboratory information management system

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Gene regulatory network inference using tree-based ensemble methods

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