Results for “mining”

Queries ClinVar for variant pathogenicity classifications, ClinGen VCEP curations, and somatic-vs-germline interpretations via REST API, weekly VCF, or bulk XML. Use when determining clinical significance, triangulating conflicting interpretations, or aggregating evidence against the ACMG/AMP framework with ClinGen SVI specifications.

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Audit a whole regression suite and prune/restructure it with evidence: per-test coverage fingerprinting, AST near-duplicate clustering, CI-history mining for never-failing and flaky tests, prune decision rules (redundant/obsolete/low-value/keep), smoke/core/extended tiering by risk and defect-detection history, and a defensible "what we deleted and why" record. Deletion is destructive — quarantine and human sign-off are mandatory. Use when: "audit the test suite," "prune redundant tests," "find duplicate tests," "which tests can we delete," "restructure into smoke/core/extended," "is this test pulling its weight," "shrink the regression suite." Not for: Judging whether an individual test is WELL-WRITTEN (smells, assertions) — that is ai-qa-review. Healing one flaky test at runtime — that is test-reliability. Bulk selector regeneration after a UI refactor — that is selector-drift-recovery. Related: ai-qa-review, coverage-analysis, test-reliability, risk-based-testing, qa-project-context.

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Mine a per-kernel optimization trace — a git repository capturing successive versions of one kernel being optimized — into structured, gate-validated optimization-experience records for the GPU kernel wiki. Use when asked to distill an optimization run, a kernel_opt trace directory or a version ladder into wiki records; to report what such a run actually achieved; to build, extend, re-run or validate the staging store behind those records; or to explain how a trace-derived record's number, snippet or provenance was established.

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Mine AI coding-agent session transcripts into structured, gate-validated GPU-kernel optimization records for the wiki. Use when asked to turn vibe-coding sessions, Codex rollout logs, or Claude Code project transcripts into wiki records; to summarise what a kernel-optimization session achieved; to build or extend a session-trace store; or to re-run and validate one. Also use when asked how a session-derived record's number, snippet, or provenance was established.

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Use when mining coding-agent session history, archived transcripts, memories, or repeated local work to discover recurring workflows that should become new Agent Skills.

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独立开发者与微型 SaaS — 单人或极小团队 (≤3 人) 构建可持续订阅收入的软件产品商业, 有别于自由职业/咨询、企业级 SaaS 和开源维护: (a) 产品发现与验证 (自己的痒 vs 市场优先 Nugent/Walling; 着陆页冒烟测试; 先接 Stripe 再写代码; JTBD 访谈适配独立开发者场景; Reddit/HN/X/社区痛点挖掘; Mom Test 验证框架; 公开构建作为验证机制); (b) 独立开发者技术架构 (无聊技术论 McKinley; 单体优先; serverless vs VPS 在 ≤$100/月预算下的取舍; Rails/Django/Laravel/Next.js 等框架的出货速度选型; 托管服务优先于自建; Supabase/PlanetScale/Neon 数据库即服务; Clerk/Auth0 认证即服务; Stripe/Paddle/LemonSqueezy 支付; Vercel/Fly.io/Railway 部署; AI 辅助编码 Cursor/Copilot 作为力量倍增器); (c) 无营销团队的分发与增长 (SEO 作为微型 SaaS 护城河; Product Hunt 发布; AppSumo 终身授权利弊; 冷邮件; Twitter/X 公开构建; IndieHackers 社区分发; 集成市场 Shopify/WordPress/Zapier/Slack 应用目录; 联盟计划; 一人内容营销); (d) 定价与变现 (SaaS 定价心理学; freemium vs 免费试用 vs 纯付费; 按席位 vs 按用量 vs 固定费率; 年付折扣; 老用户保价; 微型 SaaS 流失率控制; MRR/ARR/LTV/CAC 在微型规模的含义; $10K MRR 里程碑心理学); (e) 独立创始人心智模型与生活设计 (default alive vs default dead Graham; 拉面盈利 Levels; 生活方式生意 vs 增长生意的光谱; 独立开发者倦怠预防; 时间管理与上下文切换成本; 地理套利与远程优先; 一次构建反复销售的资产思维; 社区作为支持网络 IndieHackers/WIP/MicroConf); (f) 法务与运营基础 (公司注册地选择 LLC/Ltd/GmbH 税效; Stripe Atlas vs Firstbase vs 本地律师; 服务条款与隐私政策; GDPR/CCPA 低成本合规; 知识产权基础; 首次雇人的承包商 vs 员工选择; 独立开发者会计 SaaS — Xero/QuickBooks; 多辖区税务义务)。中国独立开发者生态: 出海作为主导策略 (从中国构建面向全球市场的产品以避开国内竞争/监管); 即刻/V2EX/少数派作为社区枢纽; 微信小程序作为替代分发; 小报童/爱发电作为中文市场变现; 人民币定价心理学; 支付宝/微信支付集成; ICP 备案要求; 中国区 App Store 审核差异; 独立开发者周刊。诚实处理: 生存偏差 (每一个 Pieter Levels 背后是数千个从未达到 $1K MRR 的人), AI 对微型 SaaS 生态位的颠覆 (wrapper 产品脆弱), 独自构建的孤独与心理健康成本, 公开构建的表演性质 vs 真正透明, AppSumo 终身授权上瘾毁坏单位经济, 样板代码销售的伦理边界。不含: 企业级 SaaS (不同 GTM/销售/融资模型), 不含: 自由职业/咨询 (用时间换钱非建资产), 不含: 开源维护 (不同可持续性模型), 不含: 风投支持的创业 (不同增长期望), 不含: 无代码/低代码平台构建 (相邻但不同受众), 不含: 内容创作作为主业。 (Independent Developer and Micro-SaaS — the craft of single-person or tiny-team (≤3 people) software product businesses that generate sustainable recurring revenue without venture capital, distinct from freelancing/consulting, enterprise SaaS, and open-source maintainership: (a) product discovery and validation (scratching your own itch vs market-first Nugent/Walling; landing page smoke tests; Stripe checkout before code; Jobs-to-Be-Done interview adapted to solo context; Reddit/HN/X/community pain-point mining; idea validation frameworks Fitzpatrick Mom Test; build-in-public as validation mechanism); (b) technical architecture for solo operators (boring technology thesis Mckinley; monolith-first; serverless vs VPS tradeoffs for ≤$100/mo infra; framework selection for shipping speed — Rails/Django/Laravel/Next.js/Remix/SvelteKit; managed services over self-hosted whenever possible; database-as-a-service Supabase/PlanetScale/Neon/Turso; auth-as-a-service Clerk/Auth0/Supabase Auth; payment integration Stripe/Paddle/LemonSqueezy; deployment Vercel/Fly.io/Railway/Render; monorepo vs polyrepo for solo; AI-assisted coding Cursor/Copilot as force multiplier); (c) distribution and growth without a marketing team (SEO as moat for micro-SaaS Ahrefs-style content marketing on 1-person budget; Product Hunt launches; AppSumo lifetime deals tradeoffs; cold email outreach; Twitter/X building in public; IndieHackers community distribution; integration marketplaces Shopify/WordPress/Zapier/Slack app directories as channels; affiliate programs; content marketing at scale-of-one); (d) pricing and monetization (SaaS pricing psychology Patel/Campbell; freemium vs free trial vs paid-only; per-seat vs usage-based vs flat-rate; annual discount strategies; grandfathering existing customers; churn reduction for micro-SaaS — Baremetrics/ProfitWell/ChartMogul analytics; MRR/ARR/LTV/CAC at micro scale; the $10K MRR milestone psychology); (e) solo founder mental model and lifestyle design (default alive vs default dead Graham; ramen profitability Levels; lifestyle business vs growth business spectrum; burnout prevention for solo operators — no team to delegate to; time management and context-switching costs; geographic arbitrage and remote-first; the 'build once sell twice' asset mindset; community as support network IndieHackers/WIP/MicroConf); (f) legal and operational basics (incorporation LLC/Ltd/Gm

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CEO (Chief Executive Officer) — 一家公司「最高操作员」的工艺, 与泛泛「领导力 / 管理学」不同: (a) 设定战略与凝结愿景 (Drucker 的「企业的经营理论」+ Porter 论定位 + Hamilton Helmer 的「七力」+ Andy Grove 的「战略转折点」+ Roger Martin 《Playing to Win》); (b) 资本配置是 CEO 单一最高杠杆的工作 (Buffett/Munger Berkshire 致股东信 + William Thorndike 《The Outsiders 商界局外人》论 8 位非常规 CEO + Michael Mauboussin 论 hurdle rate + Bezos 年度致股东信「invariants vs bets」+ Mark Leonard Constellation Software); (c) 组建与领导高管班子 (Patrick Lencioni 《团队的五大障碍》+ Ben Horowitz 《艰难的事》+ Reed Hastings 《No Rules Rules》人才密度 + Andy Grove HOP《高产出管理》+ Lou Gerstner IBM 转型 + Marshall Goldsmith); (d) 董事会与投资人关系 (Larcker & Tayan 《公司治理重要》+ Bill George 《True North》+ 正式 CEO-董事长 / CEO-独立董事 protocol + 维权投资人 playbook + 资本市场沟通); (e) 企业文化与价值观作为操作系统 (Netflix 文化手册 + Amazon Leadership Principles + Bridgewater 《Principles》Ray Dalio + Schein 论组织文化 + 任正非 灰度 + 张瑞敏 人单合一 + 稻盛和夫 阿米巴); (f) 高不确定下的高风险决策 (Bezos Type 1/Type 2 决策 + premortem Klein + Kahneman 论 executive bias + RAPID/DACI + base rates + 情景规划 + 反思 premortem); (g) 对内对外沟通 (创始人 / CEO 致股东信作为机构构建工具: Bezos / Buffett / Reed Hastings 备忘录 / 任正非 内部讲话 + Town Hall + 危机沟通 Tylenol/Boeing/Wells Fargo + 应对维权投资人); (h) 跨阶段规模化 (创业 0→1 / 扩张 1→100 / 成熟期掌舵 / 危机转型): Steve Blank + Brian Chesky founder-mode + Marc Andreessen + Pierre Lassonde + Lou Gerstner 转型; (i) 创始人 CEO vs 职业经理人 CEO 的差异 (Paul Graham 「Founder Mode」2024 + Brian Chesky + Reed Hastings (创始人→职业过渡) + BCG/McKinsey 的「manager mode」+ 两者各自代价 + 什么时候切换)。诚实处理: 幸存者偏差 (单个 CEO 的打法 ≠ 普适规律, 学术研究显示 CEO 个人方差约 ⅓, 约 70% 来自行业 / 时代 / 运气 / 资本结构), 创始人崇拜, 区分可复制工艺与不可移植个人魅力, 治理与利益相关者责任 (员工 / 股东 / 社会), 反对 CEO 神话与 Welch 退休金扭曲 / Theranos / WeWork / FTX / Uber-Kalanick 时代 / Musk 80h+ / 996 工时崇拜。覆盖 founder-CEO (Bezos/Hastings/黄仁勋/Chesky/Brin/任正非) 与职业 CEO (Nadella/Gerstner/Pichai/Mulally/Lafley)。不含: 泛泛管理理论 (商业书已覆盖, 本 skill 专谈 C-suite 这个具体岗位), 不含: 「领导力」作为个人成长自助 (Robbins/Tracy/Maxwell 励志体裁), 不含: 「如何创业」早期战术 — 一旦有员工 / 董事会 / 资本, CEO 的工艺才开始。 (CEO (Chief Executive Officer) — the craft of being the top operator of a company, distinct from generic 'leadership/management': (a) setting the strategy and crystallizing the vision (Drucker's 'theory of the business' + Porter on positioning + Hamilton Helmer's 7 powers + Andy Grove's strategic inflection points + Roger Martin Playing to Win); (b) capital allocation as the CEO's single highest-leverage job (Buffett/Munger Berkshire letters + William Thorndike 'The Outsiders' on 8 unconventional CEOs + Michael Mauboussin on hurdle rates + Bezos's annual shareholder letter approach to invariants vs bets + Mark Leonard Constellation Software); (c) building and leading the executive team (Patrick Lencioni 'Five Dysfunctions' + Ben Horowitz 'Hard Things About Hard Things' + Reed Hastings 'No Rules Rules' on talent density + Andy Grove HOP + Lou Gerstner IBM turnaround + Marshall Goldsmith); (d) board and investor relations (Larcker & Tayan 'Corporate Governance Matters' + Bill George 'True North' + the formal CEO-Chair / CEO-Lead Director protocols + activist investor playbooks + capital markets communication); (e) culture and values as operating system (Netflix culture deck + Amazon Leadership Principles + Bridgewater 'Principles' Ray Dalio + Schein on org culture + 任正非 Ren Zhengfei 灰度 + 张瑞敏 Zhang Ruimin 人单合一 + 稻盛和夫 阿米巴); (f) high-stakes decision-making under uncertainty (Bezos Type 1 vs Type 2 + premortem Klein + Kahneman 'Thinking Fast and Slow' for executive bias + RAPID/DACI + base rates + scenario planning + premortem); (g) internal and external communication (founder/CEO letters as institution-builders: Bezos shareholder letters / Buffett letters / Reed Hastings memos / 任正非 内部讲话 + Town Halls + crisis communication Tylenol/Boeing/Wells Fargo + activist responses); (h) cross-stage scaling (founder-CEO of 0→1 / scaling 1→100 / mature-stage stewardship / turnaround): Steve Blank + Brian Chesky founder-mode + Marc Andreessen + Pierre Lassonde mining vs steady-state + Lou Gerstner turnaround; (i) the founder-CEO vs professional-manager-CEO distinction (Paul Graham 'Founder Mod

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Applies the analytical and therapeutic philosophy of Ludwig Wittgenstein, 20th-century philosopher of language (Tractatus / Philosophical Investigations). Use this skill when the user is stuck in conceptual confusion, debating semantics, trapped by abstract definitions, or trying to solve a problem that is actually just a linguistic misunderstanding. Trigger this for topics involving the limits of language, meaning as use, logical clarification, or when the user is over-theorizing instead of looking at practical applications. It helps dissolve 'fly-bottle' traps by examining how words are actually used in context.

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Applies the reasoning style of Daphne Koller (machine learning pioneer, co-founder of Coursera, founder and CEO of Insitro). Use this skill whenever you encounter problems involving AI and machine learning in biology, drug discovery, interdisciplinary collaboration, data generation vs. data mining, or transitioning from academia to industry. Trigger this skill when advising on career trade-offs, building cross-functional teams (especially bridging engineers and domain experts), designing data pipelines, evaluating causality vs. correlation, or applying AI to physical systems ('where bits meet atoms'). Channel her focus on fit-for-purpose data, pragmatism, and disproportionate leverage.

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Suede-owned customer-research discipline for interview design, transcript and ticket synthesis, review and forum mining, quote banks, jobs, and evidence-backed personas. Use when discovering or synthesizing what a defined customer segment actually says, does, needs, and resists. NOT FOR: competitor-only profiling (use suede-competitor-profiling), writing final marketing copy (use suede-copy), or deciding product priorities without product evidence (use suede-product-marketing).

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Comprehensive competitor analysis, competitive intelligence, and comparison page creation. Use when analyzing competitive landscape, creating competitor comparison pages (alternative pages, vs pages, competitor A vs B pages), performing market research, building SWOT analysis, creating feature matrices, pricing comparisons, competitor teardowns, battle cards, or positioning maps. Covers research workflows, SEO-optimized comparison content, data-grounded reports with citations, 7-layer analysis framework, review mining, and sales enablement. Triggers include competitor analysis, competitive analysis, competitor teardown, vs page, alternative page, competitor comparison, market research, competitive intelligence, SWOT analysis, battle card, competitor pricing, market landscape, feature comparison, positioning map.

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Expert framework for assessing and achieving product-market fit. Combines PMF measurement methodologies, Sean Ellis survey, retention analysis, segment-specific PMF, and post-PMF scaling strategy. Use when determining if product has PMF, measuring user engagement, running PMF surveys, or deciding whether to scale or keep iterating.

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Guides user research and research ops. Use when running interviews, usability tests, surveys, or synthesis to de-risk product decisions; not experiments or review mining.

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Nexscope Ozon shop product search: fetches the product list of an Ozon shop (seller) by shop ID, returning each product's 30-day sales, price, rating, weight, fulfillment method (FBO/FBS), seller type (local/cross-border), return/cancellation rate, and the shop's total 30-day sales. Use for competitor shop product analysis, shop bestseller mining, seller product structure analysis. Trigger when the user mentions Ozon shop products, Ozon seller product list, competitor shop analysis, Ozon shop bestsellers, Ozon seller analysis, Nexscope Ozon shop search, Ozon shop search, Ozon seller products, competitor shop analysis, Ozon store products. Also trigger when the intent is to view an Ozon shop/seller's products and sales data, even without explicitly mentioning Nexscope.

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Nexscope Ozon category product search: fetches the product list for a given Ozon category ID, returning category-level aggregates (total sales, total revenue, average price, average rating, seasonality) and per-product sales, price, rating, review count, brand, seller, and fulfillment method. Use for category selection analysis, category bestseller mining, category capacity and price band analysis, seasonality assessment. Trigger when the user mentions Ozon category products, Ozon category analysis, Ozon category selection, Ozon category bestsellers, Ozon category total sales, Ozon category average price, Ozon category search, Ozon category products, category best-sellers, category analysis. Also trigger when the intent is to view products and category-level summary data within an Ozon category, even without explicitly mentioning Nexscope.

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Nexscope Ozon market hot keyword search: filters Ozon (and Wildberries) market keywords by multi-dimensional metrics including search volume, growth, product count, seller count, competitor count, price, sales, conversion concentration, etc. Each keyword carries monthly search volume, growth, market space, competitor/seller counts, average price, cart-add conversion, top products, and market profile. Use for Ozon keyword selection, blue-ocean keyword mining, and market opportunity analysis. Trigger when the user mentions Ozon hot keywords, Ozon keyword market analysis, Ozon keyword selection, Ozon blue-ocean keywords, Ozon search volume, Wildberries keywords, Nexscope Ozon, Ozon market keyword search, Ozon keyword research, blue ocean keywords Ozon. Also trigger when the intent is to filter Ozon market keywords by metrics and view market profiles, even without explicitly mentioning Nexscope.

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Nexscope Ozon keyword reverse lookup: reverse-looks up Ozon (and Wildberries) search keywords by a list of product SKUs (up to 20), returning which search terms those products appear under (organic/ad search terms), with multi-dimensional filtering by search volume, growth, product count, seller count, competitor count, natural rank, ad rank, exposure, conversion, cart-add conversion, etc. Each keyword carries monthly search volume, growth, market space, competitor/seller counts, average price, cart-add conversion, top products, and organic/ad channel, rank, exposure, and conversion (dimension) market profiles. Use for Ozon keyword reverse lookup, listing keyword optimization, competitor traffic word mining, and ad keyword analysis. Trigger when the user mentions Ozon keyword reverse lookup, Ozon reverse keyword search, Ozon SKU keyword reverse, Ozon product traffic keywords, Ozon competitor ranking keywords, Ozon organic/ad keyword reverse lookup, Nexscope Ozon, Ozon keyword back search, Ozon reverse keyword lookup, Ozon SKU keyword reverse. Also trigger when the intent is to reverse-lookup Ozon search keywords by product SKU and view market profiles, even without explicitly mentioning Nexscope.

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Surface beliefs, assumptions, stories, and values shaping a system. Use when deeper mental models need examining with care and evidence.

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Mindset theory, implicit theories of intelligence, and motivation research applied to learning. Covers fixed vs. growth mindset, the difference between process praise and ability praise, the "not yet" intervention, attribution patterns after failure, mindset critiques and the replication record, and the integration of mindset work with self-determination theory (autonomy, competence, relatedness). Use when a learner is stuck on motivation, disengaging after failure, or when a curriculum's feedback language is undermining persistence.

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Musical form and structural analysis covering binary, ternary, rondo, sonata, theme-and-variations, and popular song forms. Covers formal archetypes (AB, ABA, ABACA, sonata-allegro), 12-bar blues, arch form, minimalist process forms, strophic and through-composed designs, and formal analysis methodology for both score study and listening. Use when determining the structural plan of a piece, analyzing sectional relationships, or understanding how form shapes musical narrative.

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Spectroscopy, chromatography, titration, elemental analysis, X-ray crystallography, and mass spectrometry for chemical identification and quantitation. Covers UV-Vis and IR spectroscopy, NMR fundamentals, gas and liquid chromatography, gravimetric and volumetric analysis, diffraction methods, separation techniques, and quantitative error analysis. Use when identifying unknown substances, determining purity, measuring concentrations, or interpreting analytical data.

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Performs initial binary triage by surveying memory layout, strings, imports/exports, and functions to quickly understand what a binary does and identify suspicious behavior. Use when first examining a binary, when user asks to triage/survey/analyze a program, or wants an overview before deeper reverse engineering.

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This skill should be used when analyzing Claude Code session transcripts, reviewing agent performance, finding anti-patterns or tool misuse, mining workflow patterns, running kaizen analysis, debugging agent behavior, or performing session forensics.

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Create a structured session handoff when context is running low or work is pausing. Deep context mining, self-validation, multi-file splitting. Captures everything the next session needs.

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