Detects m6A modifications from Oxford Nanopore direct-RNA-sequencing (ONT DRS) signal data using m6Anet (Hendra 2022 *Nat Methods* 19:1590; multiple-instance-learning neural network over DRACH 5-mer signal). Covers the required upstream pipeline (Dorado / Guppy basecalling -> minimap2 transcriptome alignment with `-ax map-ont -uf -k14 --secondary=no` -> nanopolish eventalign with `--scale-events --signal-index` (m6Anet-required) plus `--summary` / `--threads` housekeeping -> m6anet dataprep -> m6anet inference), per-site vs per-read probability interpretation including the `mod_ratio` per-site stoichiometry column, the DRACH-only modeling constraint, minimum-coverage thresholds (20-50 reads per site for stable probability estimates), multi-condition comparison via xPore (Pratanwanich 2021 *Nat Biotechnol* 39:1394), Nanocompore (Leger 2021 *Nat Commun* 12:7198), ELIGOS (Jenjaroenpun 2021 *NAR* 49:e7), and Dorado native modification calling (RNA004 chemistry, 2024+), reference-transcriptome version pinning, the cDNA-vs-DRS chemistry distinction (cDNA-Nanopore CANNOT be used for modification detection), and orthogonal validation against MeRIP / GLORI. Use when calling m6A from ONT DRS without immunoprecipitation, choosing m6Anet vs xPore vs Nanocompore vs ELIGOS vs Dorado native, interpreting per-site `probability_modified` vs `mod_ratio` vs per-read modification probabilities, comparing methylation between conditions from ONT data, deciding between m6Anet for known DRACH sites and Dorado/Remora for genome-wide screening, pinning RNA002 vs RNA004 chemistry and basecaller model versions, or troubleshooting eventalign / dataprep failures.
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peacezha/HPClaw☆ 3Updated Oct 11, 2026
Build local BLAST databases and run searches using NCBI BLAST+ command-line tools. Use when running >50 queries, building custom databases with -parse_seqids and -taxid, downloading prebuilt NCBI databases via update_blastdb.pl, choosing -task variants (megablast/dc-megablast/blastn/blastn-short), tuning soft/hard masking, scaling threads, or extracting hits with blastdbcmd. Encodes BLAST v5 vs v4 database format, taxonomy filtering, makeblastdb pitfalls.
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peacezha/HPClaw☆ 3Updated Oct 11, 2026
Follow-up sweep for pending third-party provider access campaigns. Use when the recurring 30-minute Provider Access Launch dispatcher wakes, or for a manual status check of due email threads, developer portals, support cases, or review deadlines.
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armanisadeghi/ai-matrx☆ 3Updated Oct 20, 2026
Proves a Godot 4.x build is actually green and holds its project conventions. Trigger when a GUT or GDScript result needs believing (a suite green while a script failed to parse, a one-file run that ran the whole suite, drifted CI guard counts, a coverage claim, a gate figure, a failing check someone wants softened); to review scenes, signals, awaits, threads, determinism, saves, imports or .uid files, or the upgrade rule (not the migration); to prove a simulation or balance rule; for import settings and the pixel-art render precondition; or say godotsmith (check, guard, gate, review, intake). API reference is the Godot docs'; art reads pixelsmith's; audio direction soundsmith's.
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revenantworks/claude-skills☆ 2Updated Oct 20, 2026
4claw — a moderated imageboard for AI agents. Boards, threads, replies, media uploads, bumping (bump=false to not bump), greentext, and automatic capacity purges. Post spicy hot takes (what you're REALLY thinking) — but no illegal content, doxxing, harassment, or minors.
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MikeCheng1208/BattleTree☆ 2Updated Jul 22, 2026
Use when you need to apply Java concurrency best practices — including thread safety fundamentals, ExecutorService thread pool management, concurrent design patterns like Producer-Consumer, asynchronous programming with CompletableFuture, immutability and safe publication, deadlock avoidance, virtual threads and structured concurrency, scoped values, backpressure, cancellation discipline, and observability for concurrent systems. Part of the skills-for-java project
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MikeCheng1208/BattleTree☆ 2Updated Jul 22, 2026
X/Twitter API integration for posting tweets, threads, reading timelines, search, and analytics. Covers OAuth auth patterns, rate limits, and platform-native content posting. Use when the user wants to interact with X programmatically.
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sayasaya8039/ZWG_Terminal☆ 2Updated Jun 8, 2026
Create platform-native content systems for X, LinkedIn, TikTok, YouTube, newsletters, and repurposed multi-platform campaigns. Use when the user wants social posts, threads, scripts, content calendars, or one source asset adapted cleanly across platforms.
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sayasaya8039/ZWG_Terminal☆ 2Updated Jun 8, 2026
Multi-platform content distribution across X, LinkedIn, Threads, and Bluesky. Adapts content per platform using content-engine patterns. Never posts identical content cross-platform. Use when the user wants to distribute content across social platforms.
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sayasaya8039/ZWG_Terminal☆ 2Updated Jun 8, 2026
Azure AI Agents Persistent SDK for Java. Low-level SDK for creating and managing AI agents with threads, messages, runs, and tools.
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MMEHDI0606/ai-agent-foundation-template☆ 2Updated May 21, 2026
Azure AI Agents Persistent SDK for .NET. Low-level SDK for creating and managing AI agents with threads, messages, runs, and tools.
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MMEHDI0606/ai-agent-foundation-template☆ 2Updated May 21, 2026
Publish content to X/Twitter, LinkedIn, WeChat Official Account, and Xiaohongshu with one command. Automatically adapts content format for each platform — threads for Twitter, professional articles for LinkedIn, HTML drafts for WeChat, emoji notes for Xiaohongshu. Triggers: publish content, social media, twitter post, linkedin post, wechat article, xiaohongshu note, cross-platform publish, multi-platform
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aAAaqwq/openclaw-team☆ 2Updated Jun 18, 2026
Gmail API integration with managed OAuth. Read, send, and manage emails, threads, labels, and drafts. Use this skill when users want to interact with Gmail. For other third party apps, use the api-gateway skill (https://clawhub.ai/byungkyu/api-gateway).
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aAAaqwq/openclaw-team☆ 2Updated Jun 18, 2026
YouTube transcripts to summaries, threads, blogs.
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Lord1Egypt/awesome-skill-forge☆ 2Updated Jun 10, 2026
Master Java 21+ with modern features like virtual threads, pattern matching, and Spring Boot 3.x. Expert in the latest Java ecosystem including GraalVM, Project Loom, and cloud-native patterns. Use PROACTIVELY for Java development, microservices architecture, or performance optimization.
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itsimonfredlingjack/codex-dev-plugin☆ 2Updated Feb 5, 2026
Synchronizes threads and protects shared state. lock, SemaphoreSlim, Interlocked, concurrent collections.
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rudironsoni/Synaxis☆ 2Updated Mar 17, 2026
Manage persistent context threads for cross-session work
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stateforward/emel.cpp☆ 2Updated Sep 5, 2026
[BETA] AEM Cloud Service expert skill — add explicit connect/read/socket timeouts to outbound HTTP clients constructed without one (Apache HttpClient 4.x/5.x, OkHttp, JDK java.net.http.HttpClient), including the JDK per-request read timeout on HttpRequest. Use for "add HTTP timeouts", "this external/outbound call has no timeout", or a scan that flags a timeout-less client. Highest-frequency CSO outage cause: a client on default (effectively infinite) timeouts holds request threads on a slow upstream until the Jetty pool saturates and the site goes down. The analyzer locates timeout-less construction sites; mechanical per-library remediation applies CSO-backed default timeouts (recipe.md). This skill is in beta. Verify all outputs before applying them to production projects.
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aemgdc/aemdev☆ 2Updated Oct 19, 2026
Resize, crop, or export any image or video into platform-ready social media assets using Adobe Creative Cloud tools. Use this skill when a user wants to prepare a photo, image, or video for one or more social platforms — Instagram, TikTok, LinkedIn, Facebook, YouTube, Snapchat, Pinterest, Threads, or X/Twitter. Triggers on: "prepare my image for Instagram", "resize for TikTok", "get this ready to post", "make versions for all platforms", "social media sizes", "crop for stories", "export for LinkedIn", "resize my video for social", "make social media assets", or any request to adapt a photo or video for specific platforms. Handles subject-aware cropping, AI canvas expansion, test previews before full runs, and same-ratio video resizing.
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aemgdc/aemdev☆ 2Updated Oct 19, 2026
Comprehensive design skill: brand identity, design tokens, UI styling, logo generation (55 styles, Gemini, Atlas Cloud, or MuAPI AI), corporate identity program (50 deliverables, CIP mockups), HTML presentations (Chart.js), banner design (22 styles, social/ads/web/print), icon design (15 styles, SVG, Gemini 3.1 Pro), social photos (HTML→screenshot, multi-platform). Actions: design logo, create CIP, generate mockups, build slides, design banner, generate icon, create social photos, social media images, brand identity, design system. Platforms: Facebook, Twitter, LinkedIn, YouTube, Instagram, Pinterest, TikTok, Threads, Google Ads.
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sathishssj3/Stereix-Engine☆ 2Updated Oct 4, 2026
Search the web or X/Twitter using xAI Grok server-side tools (web_search, x_search) via the xAI Responses API. Use when you need tweets/threads/users from X, want Grok as an alternative to Brave, or you need structured JSON + citations.
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danstrem2/clawdbot-skill-master-pack☆ 2Updated Feb 1, 2026
Use when you need to control Discord from Clawdbot via the discord tool: send messages, react, post or upload stickers, upload emojis, run polls, manage threads/pins/search, fetch permissions or member/role/channel info, or handle moderation actions in Discord DMs or channels.
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danstrem2/clawdbot-skill-master-pack☆ 2Updated Feb 1, 2026
Manage LinkedIn outreach leads from Google Sheets — search by name, read live conversation threads, update status, and send contextual follow-up messages. Use after linkedin-dm to move leads through the pipeline (Sent → Replied → Call Scheduled → Demo Done → Closed).
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johnalbertini14-glitch/openclaw-skills☆ 2Updated Feb 26, 2026
AI-powered Reddit seeding agent for founders. Analyzes a product spec, maps relevant subreddits, finds real threads where target users need help, drafts personalized replies and DMs, and posts approved outreach via Reddit API. Use when someone wants to find and engage their first users on Reddit, seed a product launch, or do community-led growth without a budget.
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johnalbertini14-glitch/openclaw-skills☆ 2Updated Feb 26, 2026