Results for “data curation”

Orders and orients assembled contigs into chromosome-scale scaffolds from long-range linking data, inserting N-gap spacers (adds no sequence). Covers Hi-C/Omni-C scaffolding (YaHS, SALSA2, 3D-DNA/Juicer), Hi-C read-mapping prerequisites (map each end separately, no mate rescue, dedup, enzyme-aware), reading the contact map for misjoins/inversions/false-duplications, manual curation in Juicebox/PretextView (the VGP/DToL standard), reference-guided scaffolding (RagTag) and its karyotype-erasure hazard, genetic-map (ALLMAPS) and Bionano optical-map integration, chimera-breaking before scaffolding, gap-filling, and telomere/contig-vs-scaffold-N50 QC (tidk). Use when turning contigs into chromosomes with Hi-C, integrating a linkage map or optical map, choosing a scaffolder by available linking data, or judging whether a chromosome-scale assembly is trustworthy.

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Orders and orients assembled contigs into chromosome-scale scaffolds from long-range linking data, inserting N-gap spacers (adds no sequence). Covers Hi-C/Omni-C scaffolding (YaHS, SALSA2, 3D-DNA/Juicer), Hi-C read-mapping prerequisites (map each end separately, no mate rescue, dedup, enzyme-aware), reading the contact map for misjoins/inversions/false-duplications, manual curation in Juicebox/PretextView (the VGP/DToL standard), reference-guided scaffolding (RagTag) and its karyotype-erasure hazard, genetic-map (ALLMAPS) and Bionano optical-map integration, chimera-breaking before scaffolding, gap-filling, and telomere/contig-vs-scaffold-N50 QC (tidk). Use when turning contigs into chromosomes with Hi-C, integrating a linkage map or optical map, choosing a scaffolder by available linking data, or judging whether a chromosome-scale assembly is trustworthy.

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Manage your self-hosted Immich photo library through conversation: natural language and OCR search, geographic album curation, duplicate detection, people and faces, metadata repair, video frames and PDF photobooks. 94 MCP tools and 13 skills, tested live on Immich 2.x and 3.x. Install: claude plugin install immich-photo-manager

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Queries ClinVar for variant pathogenicity classifications, ClinGen VCEP curations, and somatic-vs-germline interpretations via REST API, weekly VCF, or bulk XML. Use when determining clinical significance, triangulating conflicting interpretations, or aggregating evidence against the ACMG/AMP framework with ClinGen SVI specifications.

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AI公众号信息源 — Daily scan of AI WeChat public accounts, finding the hottest articles by read count, auto-clustering into topics, and generating a styled HTML report with cover images, metrics, search, and subscription support. Use when the user wants AI daily reports, 公众号爆款, AI content curation, 每日AI热点, or 公众号日报.

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Route fastdup workflows for visual dataset curation, annotation-driven analysis, embeddings and search, and video or exchange plumbing.

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Queries ClinVar for variant pathogenicity classifications, ClinGen VCEP curations, and somatic-vs-germline interpretations via REST API, weekly VCF, or bulk XML. Use when determining clinical significance, triangulating conflicting interpretations, or aggregating evidence against the ACMG/AMP framework with ClinGen SVI specifications.

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Collect and preserve insect specimens following museum-grade standards including legal compliance, collection methods, humane dispatch, dry pinning, wet preservation, labeling, storage, and curation. Covers permit requirements, protected species regulations, sweep nets, beating trays, pitfall traps, light traps, Malaise traps, aspirators, ethyl acetate killing jars, freezing, pin placement by order, wing spreading, ethanol preservation for soft-bodied specimens, specimen labeling with locality and date, storage with pest management, and database entry. Use when building a reference collection for taxonomic study, preserving voucher specimens for ecological research, preparing specimens for identification by specialists, or curating an existing collection.

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Fine-tune large language models — data curation, SFT, parameter-efficient methods (LoRA), evaluation, and avoiding common training failures. Use when a base model needs task-specific behavior or domain knowledge.

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Use this agent when you need to perform custom bioinformatics analyses on genes or proteins that go beyond standard database lookups. This includes situations where existing domain/family annotations from UniProt are insufficient, when you need to verify dubious annotations, or when you need to perform comparative analyses across gene sets. The agent creates reproducible analysis pipelines with proper dependency management and documentation.

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Curate Gaia bot crawler branches into real-skill catalog entries and clean up processed bot/* branches. Use when the user says: "process bot branches", "curate the crawl output", "clean up bot proposals", "run bot curation", "merge the crawler results", "review bot/* branches", "ingest crawler data", or explicitly types /gaia-bot-curate. Also triggers when the user asks to review pending `bot/*` branches, turn crawler JSON proposals into registry nodes, decide which crawled skills to accept vs reject, or batch-add skills from an automated crawl run. This skill handles the full pipeline: fetch remote bot branches, triage proposals, run `gaia dev` mutations, validate, open a PR, and delete consumed bot branches.

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Complete zero-dependency memory system for AI agents — file-based architecture, daily notes, long-term curation, context management, heartbeat integration, and memory hygiene. No APIs, no databases, no external tools. Works with any agent framework.

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Queries ClinVar for variant pathogenicity classifications, ClinGen VCEP curations, and somatic-vs-germline interpretations via REST API, weekly VCF, or bulk XML. Use when determining clinical significance, triangulating conflicting interpretations, or aggregating evidence against the ACMG/AMP framework with ClinGen SVI specifications.

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Queries ClinVar for variant pathogenicity classifications, ClinGen VCEP curations, and somatic-vs-germline interpretations via REST API, weekly VCF, or bulk XML. Use when determining clinical significance, triangulating conflicting interpretations, or aggregating evidence against the ACMG/AMP framework with ClinGen SVI specifications.

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Queries ClinVar for variant pathogenicity classifications, ClinGen VCEP curations, and somatic-vs-germline interpretations via REST API, weekly VCF, or bulk XML. Use when determining clinical significance, triangulating conflicting interpretations, or aggregating evidence against the ACMG/AMP framework with ClinGen SVI specifications.

The English summary is being prepared. Showing the original description.