309 skills · sorted by relevance
Queries ClinVar for variant pathogenicity classifications, ClinGen VCEP curations, and somatic-vs-germline interpretations via REST API, weekly VCF, or bulk XML. Use when determining clinical significance, triangulating conflicting interpretations, or aggregating evidence against the ACMG/AMP framework with ClinGen SVI specifications.
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Decide when to order coronary artery calcium (CAC) scoring in a primary-prevention patient and interpret the result per the 2026 ACC/AHA multisociety dyslipidaemia guideline. Covers the Class 1 indication (men ≥40 / women ≥45, borderline / intermediate PREVENT-ASCVD risk, uncertainty about LLT), CAC score interpretation (0, 1–99, 100–299, ≥300, ≥1000), how CAC modifies LDL and non-HDL goals, when to repeat CAC, and pitfalls (incidental CAC on non-cardiac CT, radiation, cost). Use when a clinician asks should I order a CAC score, CAC indications, what does CAC 150 mean, treatment goals with CAC score, repeat CAC frequency, CAC in a smoker, CAC vs CCTA, is CAC useful in intermediate risk. Grounded in the 2026 ACC/AHA multisociety dyslipidaemia guideline.
The English summary is being prepared. Showing the original description.
Queries ClinVar for variant pathogenicity classifications, ClinGen VCEP curations, and somatic-vs-germline interpretations via REST API, weekly VCF, or bulk XML. Use when determining clinical significance, triangulating conflicting interpretations, or aggregating evidence against the ACMG/AMP framework with ClinGen SVI specifications.
The English summary is being prepared. Showing the original description.
Queries ClinVar for variant pathogenicity classifications, ClinGen VCEP curations, and somatic-vs-germline interpretations via REST API, weekly VCF, or bulk XML. Use when determining clinical significance, triangulating conflicting interpretations, or aggregating evidence against the ACMG/AMP framework with ClinGen SVI specifications.
The English summary is being prepared. Showing the original description.
Verify OpenClaw installation, onboarding, gateway operation, and upgrades in Parallels virtual machines running macOS, Windows, or Linux. The skill guides baseline restoration, bounded test runs, log interpretation, and focused retries when checks fail.
Maintain clear business definitions and relationships in an existing glossary or CONTEXT.md. Flag unresolved meanings and refer lasting design choices to the existing architecture decision record workflow, keeping terminology separate from decision rationale and task status.
Investigate photos, videos, public accounts, and records using OSINT, research based on public information. Connect sparse clues, test competing explanations, and report evidence, confidence, and unresolved questions about locations, events, identities, or infrastructure relationships.
Support manufacturing quality investigations from containment through root cause analysis and corrective action. Organize decisions about nonconforming materials, assess whether actions prevent recurrence, interpret process control charts, and address supplier quality problems.
Check whether ARIA attributes, which describe interface elements to assistive technology, are supported by each element’s role. Review rendered HTML and interactive states, identify invalid combinations, and suggest removals or corrections to support accurate screen reader interpretation.
Plan A/B tests to compare page changes using clear hypotheses and meaningful measures. The skill helps define sample size, duration, traffic allocation, and result interpretation, and organize a continuing program of prioritized experiments.
Fit probabilistic models to single-cell measurements for integration across experiments, cell annotation, combined RNA and protein or ATAC analysis, and gene expression comparisons. The skill covers input requirements, training checks, reference mapping, and interpretation of model uncertainty.
Assess scientific claims by examining study design, statistics, bias, and evidence quality. Use structured appraisal frameworks to identify supported conclusions, explain uncertainties, and propose practical improvements with concerns traced to specific evidence.
Generate candidate positions and orientations for small molecules binding to proteins with DiffDock and DiffDock-L. Prepare single or batch docking runs, organize predicted poses by model confidence, and review validation needs without treating confidence as binding affinity.
Clarify ambiguous requests before implementation by asking a small set of essential questions. Use concise choices and suggested defaults to agree on goals, scope, constraints, and completion criteria before starting work that depends on those answers.
Organize supplied health records, including sleep, exercise, nutrition, and test results, to describe trends, relationships, and risk factors. Prepare general health information, summaries, and questions for a doctor, with clear limits on medical interpretation.
Compare how proxies and backend servers interpret HTTP requests in a CTF sandbox. Use paired requests and logs to pinpoint differences in paths, headers, or message boundaries, then document a minimal reproduction of unintended routing.
Use a constructive thinking partner to review assumptions, separate evidence from interpretation, and test alternative explanations. Refine conclusions and wording so claims match the available evidence and support decisions under uncertainty.
Interpret crypto liquidation heatmaps, which show estimated price levels where leveraged positions may be forcibly closed. Organize major clusters, compare concentrations above and below the current price, and assess cascade risks and potential support or resistance zones.
Interpret economic indicators and central bank policy across China, the United States, and Europe. Identify the economic cycle stage and produce a structured assessment of whether to increase, maintain, or reduce allocations to major asset classes.
Query documents and conversations stored in cognee to retrieve answers, supporting passages, or context for an AI model. This skill guides search method selection, source filtering, result interpretation, and troubleshooting empty or unexpected results.
Investigate and fix agent behavior in TradingAgentsCN by checking active database prompt templates, prompt assembly code, and output processing. Apply targeted changes and verify them with focused tests, template checks, and workflow logs.
Analyze competitors using deal outcomes, customer quotes, and public developments. Prepare tactics for a specific deal, battlecards—sales reference sheets for each competitor—and weekly updates that distinguish evidence from interpretation.
Analyze data distributions, trends, unusual values, and differences between groups using suitable statistical methods. The skill guides interpretation of effect sizes, meaning the magnitude of differences, alongside uncertainty and business impact, while checking for misleading conclusions.
Helps agents find and use OpenCLI commands for websites and Chrome. It guides command discovery, input checks, result interpretation, and error recovery so agents can select suitable browser tools or reusable website commands.