Results for “modelling”

Assigns pathogen lineages (SARS-CoV-2 Pangolin UShER mode; Nextclade clade + QC; pango-designation alias resolution) and tracks variant frequencies over time using Nextstrain (Augur + Auspice), wastewater deconvolution (Freyja, COJAC, alcov, lineagespot), lineage-fitness modelling (multinomial logistic), and recombinant detection (3SEQ, RDP4, Bolotie). Covers Pangolin pangolin-data and Nextclade dataset version pinning (mandatory; lineage-defining mutations change with dataset), Freyja barcode forward-only date constraint, ARTIC primer scheme churn (V3/V4/V4.1/V5.3.2/Midnight) with dropout regions, and recombinant X-prefix designation lag. Use when assigning Pango lineages and Nextclade clades to viral consensus sequences, building Nextstrain Augur surveillance pipelines, deconvolving wastewater into lineage frequencies with Freyja, tracking lineage frequencies over time, handling ARTIC primer dropouts, or running surveillance for SARS-CoV-2/influenza/Mpox/RSV/H5N1/measles.

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Knowledge base from NIST Secure Software Development Framework (SSDF) v1.1 (SP 800-218). Use for secure software development practices, SDLC security integration, software supply chain security, vulnerability disclosure, SBOM, threat modelling, secure coding, build hardening, EO 14028 compliance. Covers the four SSDF practice groups (PO, PS, PW, RV) only; does not cover NIST CSF, SP 800-53 controls, or cloud-specific security frameworks in depth.

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Knowledge base synthesized from the Guide to the Systems Engineering Body of Knowledge (SEBoK) v2.14 by the BKCASE Project. Use for the established systems-engineering canon: SE fundamentals and foundations (systems science, systems thinking, the systems approach, modelling/MBSE), the life cycle (ISO/IEC/IEEE 15288/24748/24774 process, development & agile approaches, model selection/tailoring), technical management, concept definition, architecture/realization (the Vee), V&V, maintenance/sustainment, SE standards, and the application contexts (product, service, enterprise, systems-of-systems, healthcare), plus enabling SE (business/team/individual), related disciplines, quality attributes/specialty engineering, implementation examples, and emerging knowledge. Good for grounding background, vocabulary, and prior-art positions across all eight SEBoK Parts. SCOPE LIMITS: this pack is SEBoK v2.14 only (released 2026-05-18); it synthesizes and signposts rather than reproducing the source — it does not reproduce ISO/IEC/IEEE standard text, is a curated guide (not a complete textbook), and is thin on AI-integration depth (Part 8 is a staging area, not settled practice). LICENCE: content is CC BY-NC-SA 3.0 — non-commercial use only, attribution to the BKCASE Project required, share-alike obligations carry forward.

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Create, edit, or debug parametric 3D CAD parts in CadQuery (Python) that export to STEP for SolidWorks. Use when the request involves CadQuery, .step/.stl export, or modelling a physical part — enclosure, bracket, PCB, motor mount, cam, gear. Also use when a STEP will not open in CAD, or geometry looks correct in STL but is invalid as a solid. Applies a verification discipline before export and documented OCC pitfalls.

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Assigns pathogen lineages (SARS-CoV-2 Pangolin via UShER mode; Nextclade clade + QC; pango-designation alias_key.json resolution) and tracks variant frequencies over time using Nextstrain (Augur + Auspice), wastewater deconvolution (Freyja, COJAC, alcov, lineagespot), lineage fitness modelling (Wenseleers / Bedford-Figgins multinomial logistic), and recombinant detection (3SEQ, RDP4, Bolotie). Covers Pangolin pangolin-data version pinning (mandatory for reproducibility), Nextclade dataset versioning (lineage-defining mutations change with dataset), Freyja barcode forward-only date constraint, ARTIC primer scheme version churn (V3 / V4 / V4.1 / V5.3.2 / Midnight 1200) with documented dropout regions, recombinant X-prefix Pango designation lag, GISAID vs INSDC dual-deposition tensions, and the Karthikeyan 2022 wastewater early-detection signal with explicit reproducibility caveats. Use when assigning Pango lineages and Nextclade clades to viral consensus sequences, building Nextstrain Augur surveillance pipelines, deconvolving wastewater pooled samples into lineage frequencies with Freyja, tracking lineage frequencies and growth advantages over time, pinning pangolin-data / Nextclade dataset versions for reproducibility, handling ARTIC primer dropouts (V4.1 amplicons 64 / 76 / 88-90), or running variant surveillance for SARS-CoV-2 / influenza / Mpox / RSV / H5N1 / measles.

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Assigns pathogen lineages (SARS-CoV-2 Pangolin via UShER mode; Nextclade clade + QC; pango-designation alias_key.json resolution) and tracks variant frequencies over time using Nextstrain (Augur + Auspice), wastewater deconvolution (Freyja, COJAC, alcov, lineagespot), lineage fitness modelling (Wenseleers / Bedford-Figgins multinomial logistic), and recombinant detection (3SEQ, RDP4, Bolotie). Covers Pangolin pangolin-data version pinning (mandatory for reproducibility), Nextclade dataset versioning (lineage-defining mutations change with dataset), Freyja barcode forward-only date constraint, ARTIC primer scheme version churn (V3 / V4 / V4.1 / V5.3.2 / Midnight 1200) with documented dropout regions, recombinant X-prefix Pango designation lag, GISAID vs INSDC dual-deposition tensions, and the Karthikeyan 2022 wastewater early-detection signal with explicit reproducibility caveats. Use when assigning Pango lineages and Nextclade clades to viral consensus sequences, building Nextstrain Augur surveillance pipelines, deconvolving wastewater pooled samples into lineage frequencies with Freyja, tracking lineage frequencies and growth advantages over time, pinning pangolin-data / Nextclade dataset versions for reproducibility, handling ARTIC primer dropouts (V4.1 amplicons 64 / 76 / 88-90), or running variant surveillance for SARS-CoV-2 / influenza / Mpox / RSV / H5N1 / measles.

The English summary is being prepared. Showing the original description.