531 skills · sorted by relevance
Atonement is an expression of care that may arise in an intelligence when its actions contribute to harm.
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Expert-level biochemistry knowledge. Use when working with proteins, enzymes, metabolism, DNA, RNA, carbohydrates, lipids, cell signaling, or bioenergetics. Also use when the user mentions 'enzyme kinetics', 'metabolism', 'glycolysis', 'Krebs cycle', 'DNA replication', 'protein folding', 'amino acids', 'ATP', 'oxidative phosphorylation', 'gene expression', 'lipid bilayer', or 'signal transduction'.
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Expert-level molecular biology knowledge. Use when working with DNA replication, transcription, translation, gene regulation, cloning, PCR, sequencing, CRISPR, epigenetics, or molecular techniques. Also use when the user mentions 'DNA replication', 'transcription', 'translation', 'gene expression', 'PCR', 'cloning', 'restriction enzyme', 'gel electrophoresis', 'Western blot', 'CRISPR', 'epigenetics', 'promoter', 'enhancer', or 'RNA splicing'.
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Use when configuring Laravel task scheduling — cron expressions, frequency helpers, overlap prevention, maintenance mode, or output handling.
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Type design analysis — encapsulation, invariant expression, usefulness, and enforcement.
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Type design analysis — encapsulation, invariant expression, usefulness, and enforcement.
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Use this skill when a user asks to polish, rewrite, humanize, de-AI, localize, or oralize Chinese writing, including short-video scripts, articles, social posts, speeches, newsletters, and personal-IP content. The skill diagnoses “AI味”, preserves the user's meaning, adapts to optional style samples, replaces translation-like phrasing with natural Chinese expression, and outputs a polished version plus concise revision notes.
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Validate and implement Sinclair ZX Spectrum 48K ROM-visible behavior in the EMULATORS repository, including reset and restart vectors, IM1/NMI handling, keyboard scanning and repeat, beeper and tape routines, screen/printer output, channels and streams, BASIC tokenization and execution, expression evaluation, memory movement, system variables, calculator stack, floating-point formats, ROM traps, localized ROM selection, and firmware/hardware timing contracts. Use when Codex reviews or edits ZX Spectrum ROM loading, KERNAL-style traps, keyboard, tape, screen, printer, BASIC files, tokens, system variables, startup, interrupts, or compatibility tests.
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Scans GitHub Actions workflows and CI/CD pipeline configurations for supply chain attack vectors including unpinned actions, script injection via expressions, dependency confusion, and secrets exposure. Uses PyGithub and YAML parsing for automated audit. Use when hardening CI/CD pipelines or investigating compromised build systems.
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Parse Windows PowerShell Script Block Logs (Event ID 4104) from EVTX files to detect obfuscated commands, encoded payloads, and living-off-the-land techniques. Uses python-evtx to extract and reconstruct multi-block scripts, applies entropy analysis and pattern matching for Base64-encoded commands, Invoke-Expression abuse, download cradles, and AMSI bypass attempts.
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Apply a set of Rosetta Stone attribute mappings to a Narrative dataset by wrapping them in a one-shot workflow that calls the `CreateRosettaStoneMappingsIfNotExist` task. Consumes the structured output of `/generate-rosetta-stone-mappings`, normalizes the generator's snake_case to the workflow task's camelCase, re-validates every expression against the dataset's current schema, gates on user approval, submits via `narrative_workflows_create`, polls the triggered run, and reports per-mapping created / conflict / failed. Use when: "apply these mappings to dataset N", "create the Rosetta Stone mappings I just generated", "push the mappings I saved earlier to <dataset>", "productionize this mapping list", "submit the suggested_mappings array". (narrative-common)
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Design and review Action Scheduler jobs in WordPress plugins using Action Scheduler 3.9.x public APIs - async, single, recurring, and cron-expression actions; action_scheduler_init load timing; hook/args/group naming; unique and priority parameters; idempotent callbacks; chunked workloads; activation/deactivation cleanup; WooCommerce-bundled or standalone dependency usage; admin and WP-CLI debugging; queue runner limits; and safe operational troubleshooting. Use when a plugin schedules background jobs with as_enqueue_async_action, as_schedule_single_action, as_schedule_recurring_action, as_schedule_cron_action, as_get_scheduled_actions, or integrates with WooCommerce background queues.
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Performs numerical and symbolic mathematics using NumPy, SciPy, SymPy, and mpmath. Use when the user needs linear algebra, arrays, optimization, integration, ODEs, symbolic expressions, equation solving, or arbitrary-precision arithmetic.
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Comprehensive regular expressions guide covering character classes, quantifiers, anchors, groups, lookahead/lookbehind, common patterns (email, URL, IP, phone, dates, semver), ReDoS prevention, Unicode support, flags, debugging, and when NOT to use regex.
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GRN inference from expression via GRNBoost2 (gradient boosting) or GENIE3 (Random Forest). Load matrix, filter by TFs, infer TF-target-importance links, save network. Dask-parallelized to single-cell scale. Core SCENIC component.
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AI-powered design of armored CAR-T cells with cytokine/chemokine expression for enhanced solid tumor efficacy, including IL-12, IL-15, IL-18, and IL-7 armoring strategies.
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Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.
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Expert en n8n avancé (workflows, nodes, expressions, webhooks, self-hosted, custom nodes, scaling, error handling)
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Apply modern Swift language patterns and idioms for non-concurrency, non-SwiftUI code. Covers if/switch expressions (Swift 5.9+), typed throws (Swift 6+), result builders, property wrappers, opaque and existential types (some vs any), guard patterns, Never type, Regex builders (Swift 5.7+), Codable best practices (CodingKeys, custom decoding, nested containers), modern collection APIs (count(where:), contains(where:), replacing()), FormatStyle (.formatted() on dates, numbers, measurements), and string interpolation patterns. Use when writing core Swift code involving generics, protocols, enums, closures, or modern language features.
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Parse Windows PowerShell Script Block Logs (Event ID 4104) from EVTX files to detect obfuscated commands, encoded payloads, and living-off-the-land techniques. Uses python-evtx to extract and reconstruct multi-block scripts, applies entropy analysis and pattern matching for Base64-encoded commands, Invoke-Expression abuse, download cradles, and AMSI bypass attempts.
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GitHub Actions security review for workflow exploitation vulnerabilities. Use when asked to "review GitHub Actions", "audit workflows", "check CI security", "GHA security", "workflow security review", or review .github/workflows/ for pwn requests, expression injection, credential theft, and supply chain attacks. Exploitation-focused with concrete PoC scenarios.
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Calculates statistical power for high-dimensional genomics experiments (bulk RNA-seq, scRNA-seq, ATAC-seq, ChIP-seq, methylation, proteomics) under negative-binomial count models using RNASeqPower, PROPER, and simulation via powsimR, distinguishing per-gene from marginal (transcriptome-wide) power, the role of mean expression and dispersion, and the sequencing-depth-versus-replicate tradeoff. Covers simulation as the honest default for overdispersed counts, FDR-aware average power versus single-test power, observed/post-hoc power as an anti-pattern, and the winner's-curse / Type-S / Type-M consequences of underpowering. Use when planning replicate number for a sequencing experiment, deciding whether to add depth or samples, choosing closed-form versus simulation power, estimating power from pilot dispersions, or justifying replication in a grant. For clinical-trial power see clinical-biostatistics/power-and-sample-size; for the inverse sample-size question see experimental-design/sample-size.
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Designs genomics experiments so technical nuisance variation (batch, lane, plate, flow cell, operator, reagent lot, processing day) is balanced against the biological variable of interest and therefore estimable rather than confounded, using constrained sample-to-batch assignment (designit, OSAT), the confounder/mediator/collider distinction, and the principle that no post-hoc correction recovers a fully confounded design. Covers detecting hidden batches with surrogate variable analysis, a decision table for downstream correction (ComBat-seq, RUVSeq, SVA) whose execution is deferred to differential-expression/batch-correction, and reproducibility metadata. Use when assigning samples to sequencing batches/lanes/plates, avoiding batch-condition confounding, deciding whether a design is salvageable by correction, choosing a correction method, or estimating the number of hidden batches. For the experimental unit, randomization, and blocking concepts see experimental-design/randomization-blocking.
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Plot per-group distributions of continuous data using boxplots, violins, beeswarms, quasirandom jitter, and raincloud plots with sample-size honesty (Weissgerber 2015), KDE-bandwidth awareness, and N-aware encoding choices. Use when comparing distributions across a small number of groups — expression per cluster, biomarker per arm, scores per condition — and the bar-of-mean default is misleading.
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