High-performance reinforcement learning framework optimized for speed and scale. Use when you need fast parallel training, vectorized environments, multi-agent systems, or integration with game environments (Atari, Procgen, NetHack). Achieves 2-10x speedups over standard implementations. For quick prototyping or standard algorithm implementations with extensive documentation, use stable-baselines3 instead.
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huang-sh/DeepScience☆ 4Updated Jul 15, 2026
Language-independent tokenizer treating text as raw Unicode. Supports BPE and Unigram algorithms. Fast (50k sentences/sec), lightweight (6MB memory), deterministic vocabulary. Used by T5, ALBERT, XLNet, mBART. Train on raw text without pre-tokenization. Use when you need multilingual support, CJK languages, or reproducible tokenization.
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huang-sh/DeepScience☆ 4Updated Jul 15, 2026
Fast tokenizers optimized for research and production. Rust-based implementation tokenizes 1GB in <20 seconds. Supports BPE, WordPiece, and Unigram algorithms. Train custom vocabularies, track alignments, handle padding/truncation. Integrates seamlessly with transformers. Use when you need high-performance tokenization or custom tokenizer training.
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huang-sh/DeepScience☆ 4Updated Jul 15, 2026
Builds diagnostic and prognostic classifiers on omics feature matrices with regularized logistic regression, random forest, and gradient-boosted trees, handling the p>>n regime, batch shortcut learning, class imbalance, and probability calibration. Use when building a classifier from expression, methylation, or variant data, choosing an algorithm for high-dimensional small-n data, or diagnosing a suspiciously perfect AUC. For unbiased evaluation see machine-learning/model-validation; for feature selection see machine-learning/biomarker-discovery; for time-to-event outcomes see machine-learning/survival-analysis.
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huang-sh/DeepScience☆ 4Updated Jul 15, 2026
Generate the success criteria for a task or question, then review work against them. Given a task, goal, or open-ended question, decompose it into scenarios, evaluation perspectives, and fine-grained weighted YES/NO criteria using the Recursive Expansion Tree (RET) method; if work is supplied, score it criterion-by-criterion and surface what is missing or could be better. Use when asked to self-review or check your own work, judge whether a task is done well or completely, build a definition-of-done or completeness checklist, create an evaluation rubric or grading criteria, score or grade answers to a question, set up an LLM-as-judge rubric, or when the user mentions self-review, completeness check, success criteria, evaluation criteria, scoring rubric, Qworld, or the RET algorithm.
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huang-sh/DeepScience☆ 4Updated Jul 15, 2026
This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.
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huang-sh/DeepScience☆ 4Updated Jul 15, 2026
Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.
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huang-sh/DeepScience☆ 4Updated Jul 15, 2026
Machine learning in Python with scikit-learn. Use when working with supervised learning (classification, regression), unsupervised learning (clustering, dimensionality reduction), model evaluation, hyperparameter tuning, preprocessing, or building ML pipelines. Provides comprehensive reference documentation for algorithms, preprocessing techniques, pipelines, and best practices.
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huang-sh/DeepScience☆ 4Updated Jul 15, 2026
Cheminformatics toolkit for fine-grained molecular control. SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure search, 2D/3D generation, similarity, reactions. For standard workflows with simpler interface, use datamol (wrapper around RDKit). Use rdkit for advanced control, custom sanitization, specialized algorithms.
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huang-sh/DeepScience☆ 4Updated Jul 15, 2026
Complete mass spectrometry analysis platform. Use for proteomics workflows feature detection, peptide identification, protein quantification, and complex LC-MS/MS pipelines. Supports extensive file formats and algorithms. Best for proteomics, comprehensive MS data processing. For simple spectral comparison and metabolite ID use matchms.
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huang-sh/DeepScience☆ 4Updated Jul 15, 2026
Upstash サーバーレスデータプラットフォーム (マネージド SaaS の JS SDK)。 @upstash/redis (REST, pipelining, transactions, JSON, Redis Search, VECTOR/Array/Functions コマンド)、 @upstash/ratelimit (Fixed/Sliding Window, Token Bucket, blockUntilReady)、 QStash (publishJSON, schedules, queues, URL Groups, flow-control, DLQ)、 @upstash/vector (upsert, query, ANN, namespace, hybrid/sparse index, embedding models, reranking)、 @upstash/workflow (serve, durable execution, context.run/sleep/call/invoke, waitForEvent, parallel steps, agents)、 Upstash Search (@upstash/search, search, upsert, fetch, range, filtering, reranking, algorithm)、 @upstash/box (サンドボックス, filesystem, git, CDP, browser, network policy, snapshots, custom harness)、 upstash CLI。Rust 製 fandhe-db とは別。
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Fandhe-AI/agent-reference-skills☆ 4Updated Oct 20, 2026
Philosophy-first writing partner for Medium with tactical depth. Combines human storytelling values with production-ready technical content tools. Six content modes based on staff pick analysis, mode-specific quality gates, evidence requirements, annotated examples, and comprehensive scripts integration. Designed for sustainable practice, not algorithm gaming.
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alirezarezvani/medium-content☆ 4Updated Apr 11, 2026
Unsupervised clustering and cell-type identification for high-dimensional flow, spectral, and mass cytometry - FlowSOM, PhenoGraph, FlowSOM-via-CATALYST, with UMAP/tSNE for visualization. Covers the type-vs-state marker distinction (cluster on lineage, test state within clusters), over-provision-then-metacluster, the Weber-Robinson benchmark, seed dependence and metacluster stability, why embeddings are for looking not measuring, and median-heatmap annotation/merging. Use when discovering populations without predefined gates, choosing a clustering algorithm, selecting the number of metaclusters, or annotating clusters into cell types.
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peacezha/TRACE☆ 3Updated Oct 20, 2026
Visualize biological networks (PPI, gene-regulatory, co-expression, pathway) with layout algorithm choice (ForceAtlas2, Fruchterman-Reingold, Kamada-Kawai, hive plots), edge bundling, community-based coloring, and reproducible seeds using NetworkX, PyVis, igraph, and Cytoscape automation. Use when rendering biological networks for static publication, interactive HTML exploration, or Cytoscape-format export.
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peacezha/TRACE☆ 3Updated Oct 20, 2026
Perform multiple sequence alignment using MAFFT, MUSCLE5, ClustalOmega, or T-Coffee. Guides tool and algorithm selection based on dataset size, sequence divergence, and downstream application. Use when aligning three or more homologous sequences for phylogenetics, conservation analysis, or evolutionary studies.
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peacezha/TRACE☆ 3Updated Oct 20, 2026
Fast tokenizers optimized for research and production. Rust-based implementation tokenizes 1GB in <20 seconds. Supports BPE, WordPiece, and Unigram algorithms. Train custom vocabularies, track alignments, handle padding/truncation. Integrates seamlessly with transformers. Use when you need high-performance tokenization or custom tokenizer training.
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ibragimov-oasis/vibe-coder☆ 3Updated Jun 24, 2026
Create and train AI learning plugins with AgentDB's 9 reinforcement learning algorithms. Includes Decision Transformer, Q-Learning, SARSA, Actor-Critic, and more. Use when building self-learning agents, implementing RL, or optimizing agent behavior through experience.
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ibragimov-oasis/vibe-coder☆ 3Updated Jun 24, 2026
Unsupervised clustering and cell-type identification for high-dimensional flow, spectral, and mass cytometry - FlowSOM, PhenoGraph, FlowSOM-via-CATALYST, with UMAP/tSNE for visualization. Covers the type-vs-state marker distinction (cluster on lineage, test state within clusters), over-provision-then-metacluster, the Weber-Robinson benchmark, seed dependence and metacluster stability, why embeddings are for looking not measuring, and median-heatmap annotation/merging. Use when discovering populations without predefined gates, choosing a clustering algorithm, selecting the number of metaclusters, or annotating clusters into cell types.
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peacezha/HPClaw☆ 3Updated Oct 11, 2026
Visualize biological networks (PPI, gene-regulatory, co-expression, pathway) with layout algorithm choice (ForceAtlas2, Fruchterman-Reingold, Kamada-Kawai, hive plots), edge bundling, community-based coloring, and reproducible seeds using NetworkX, PyVis, igraph, and Cytoscape automation. Use when rendering biological networks for static publication, interactive HTML exploration, or Cytoscape-format export.
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peacezha/HPClaw☆ 3Updated Oct 11, 2026
Perform multiple sequence alignment using MAFFT, MUSCLE5, ClustalOmega, or T-Coffee. Guides tool and algorithm selection based on dataset size, sequence divergence, and downstream application. Use when aligning three or more homologous sequences for phylogenetics, conservation analysis, or evolutionary studies.
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peacezha/HPClaw☆ 3Updated Oct 11, 2026
Apply practical DAG decomposition, transitive-edge reduction, and reachability indexing to dense dependency graphs. Use when low width and repeated queries justify preprocessing. NOT for cyclic graphs, one-off graph checks, or exact-minimum-chain requirements.
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curiositech/port-daddy☆ 3Updated Oct 19, 2026
Apply practical DAG decomposition, transitive-edge reduction, and reachability indexing to dense dependency graphs. Use when low width and repeated queries justify preprocessing. NOT for cyclic graphs, one-off graph checks, or exact-minimum-chain requirements.
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curiositech/port-daddy☆ 3Updated Oct 19, 2026
Build and validate a static DAG reachability index from source-qualified path/chain decompositions and partial transitive-edge filtering. NOT for treating a partial edge filter as a complete transitive reduction or runtime scheduler.
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curiositech/port-daddy☆ 3Updated Oct 19, 2026
Validate finite-DAG order objectives and construct reachability-chain or direct-edge path partitions with explicit proof boundaries. NOT for equating reachability chains with direct-edge paths without checking the chosen objective.
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curiositech/port-daddy☆ 3Updated Oct 19, 2026