Results for “ray”

Processes eDNA metabarcoding from raw paired-end reads to species tables, navigating ASV (DADA2, UNOISE3) vs OTU (swarm v2) decision (Callahan 2017 vs Schloss multi-copy-16S critique), marker/primer choice (Leray COI, MiFish 12S, 515F/806R 16S, ITS2) with primer-specific bias, OBITools3 v3 command-name break (obi stats plural; .tar.gz taxonomy), tag-jumping with dual-indexing (Schnell 2015; NovaSeq 10x MiSeq), decontam as screening-not-classifier (Davis 2018), read-counts-not-abundance critique (Lamb 2019), site-occupancy modeling (Ficetola 2015), Naive-Bayes calibration limits (Bokulich 2018), and eDNA decay (Strickler 2015). Use when going from raw eDNA FASTQ to species tables, picking marker + denoising pipeline, deciding whether read counts represent abundance, applying occupancy modeling, configuring OBITools3 v3, or interpreting decontam output. Not for clinical 16S microbiome (see microbiome/amplicon-processing).

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Designs and analyzes combinatorial CRISPR screens covering paired-Cas9 (Big Papi, Najm 2018), enhanced AsCas12a multiplex (enCas12a, DeWeirdt 2021), in4mer 4-guide-array Cas12a (Esmaeili Anvar N et al 2024 Nat Commun 15:3577) and the Inzolia paralog-pair library, paralog-buffering detection (Dede 2020 Genome Biol; Thompson 2021 Cell Reports 36:109597), genetic-interaction (GI) scoring as observed_double_LFC minus expected_additive_double_LFC, synthetic-lethal and synthetic-rescue interaction interpretation, the half-of-essentiality buffered by paralogs phenomenon, multiplex screen statistical analysis with MAGeCK MLE interaction terms, and the relationship to single-cell combinatorial Perturb-seq. Use when designing a paralog or pathway-pair screen, choosing between paired-Cas9 (Big Papi) and Cas12a multiplex (Inzolia), interpreting genetic interaction scores, identifying synthetic-lethal targets for drug development, or scaling beyond single-gene CRISPR screens.

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Performs time-to-event analysis for clinical trials including Cox proportional hazards regression with PH diagnostics, restricted mean survival time (RMST) under non-PH, competing risks via Fine-Gray vs cause-specific Cox, weighted log-rank and MaxCombo for non-proportional hazards, recurrent events (Andersen-Gill, PWP, WLW), and interval-censored data. Use when analyzing time-to-event endpoints (OS, PFS, DOR, TTR, TTNT) in oncology or other clinical trials.

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End-to-end form handling with react-hook-form, Zod schemas, validation patterns, error messaging, field arrays, and multi-step wizards. Use for complex forms, validation architecture, autosave, field dependencies. Activate on "form validation", "react-hook-form", "Zod", "form error", "multi-step form", "wizard". NOT for simple HTML forms, backend validation only, or non-React frameworks.

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WindowPanel (@ai-matrx/summon/window) and its window manager. Use when a window won't drag, resize, minimize or pop out, the tray or restore is wrong, rendering <WindowPanel> on a page, or editing features/window-panels/**. NOT for opening or registering overlays (use overlay-system).

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Recipe for creating or changing a floating window. Use when adding a window, deleting, killing or retiring a window or overlay ('kill this panel', 'remove the X window', consolidating X into Y and deleting X), editing a window component, declaring restore or ephemeral behavior, wiring a ?panels= link or the Tools grid, or a window fails to restore after reload. NOT for drag/resize/tray internals (use window-panels) or for opening an overlay (use overlay-system).

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Three.js interaction - raycasting, controls, mouse/touch input, object selection. Use when handling user input, implementing click detection, adding camera controls, or creating interactive 3D experiences.

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Add strategic color to features that are too monochromatic or lack visual interest, making interfaces more engaging and expressive. Use when the user mentions the design looking gray, dull, lacking warmth, needing more color, or wanting a more vibrant or expressive palette.

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Generates InMemory repository implementations for PHP 8.5 testing. Creates fake repositories with array storage, supporting CRUD operations and queries without database.

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PostgreSQL-specific code review assistant focusing on PostgreSQL best practices, anti-patterns, and unique quality standards. Covers JSONB operations, array usage, custom types, schema design, function optimization, and PostgreSQL-exclusive security features like Row Level Security (RLS).

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PostgreSQL-specific development assistant focusing on unique PostgreSQL features, advanced data types, and PostgreSQL-exclusive capabilities. Covers JSONB operations, array types, custom types, range/geometric types, full-text search, window functions, and PostgreSQL extensions ecosystem.

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Optimizes .NET allocations and throughput. Span, ArrayPool, ref struct, sealed, stackalloc.

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Tunes GC and memory. GC modes, LOH/POH, Gen0/1/2, Span/Memory deep patterns, ArrayPool.

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Detects anomalous authentication patterns using UEBA analytics, statistical baselines, and machine learning models to identify impossible travel, credential stuffing, brute force, password spraying, and compromised account behaviors across authentication logs. Activates for requests involving authentication anomaly detection, login behavior analysis, UEBA implementation, or suspicious sign-in investigation.

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Build GLSL/WebGL/ShaderToy shaders and procedural visual effects such as SDF, ray marching, particles, and fluids.

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Okta-as-IdP red-team attack chain — tenant discovery, user enumeration (multiple vectors), authentication flow analysis (factors enumeration, push-notification fatigue, SMS bypass), password spray with lockout discipline, Okta-specific phishing primitives (kits, FastPass abuse, OIDC redirect_uri tampering), MFA enumeration, post-compromise admin API surface. Many enterprise orgs use Okta instead of (or alongside) Entra ID. Distinct endpoints, distinct rate-limiting, distinct factor flows. Use when recon shows `<tenant>.okta.com`, `<tenant>.okta-emea.com`, `<tenant>.oktapreview.com`, or autodiscover-style records pointing at Okta IdP.

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Meme coin and token security audit — rug pull detection (honeypot, hidden mint, fee manipulation, LP lock bypass), Solana SPL token analysis (freeze authority, mint authority, metadata mutability), Token-2022 extension risks (transfer hooks, permanent delegate), DEX liquidity pool attacks (sandwich amplification, LP drain, bonding curve exploits), pump.fun/Raydium/Jupiter integration risks, and real exploit examples from 2024-2025. Use for any token audit, rug pull assessment, meme coin security review, or pre-investment due diligence.

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