Analyzes alternative splicing from PacBio Iso-Seq (HiFi, Kinnex/MAS-Iso-seq) and Oxford Nanopore (direct cDNA, direct RNA, R10.4.1+) long-read RNA-seq with full-isoform resolution. Tools include FLAIR (correct/collapse/quantify/diffSplice for PacBio + ONT), IsoQuant (de-novo or annotation-guided isoform discovery 2024 SOTA), Bambu (annotation-aware Bayesian discovery + quantification with Novel Discovery Rate), SQANTI3 (isoform classification: FSM/ISM/NIC/NNC + artifact flags), rMATS-long (event calling on long-read isoforms), and minimap2 (-ax splice:hq for HiFi; -ax splice -k14 for ONT cDNA; add -uf only for direct RNA or stranded cDNA preps). Solves microexon detection, recursive splicing, complex multi-exon isoforms, and DTU without transcript-quantification uncertainty. Use when short-read AS limitations (anchor length, complex isoforms, microexons, recursive splicing, transcript ambiguity) demand full-isoform resolution.
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GPTomics/bioSkills☆ 1.2KUpdated Aug 15, 2026
Deep research and discovery before building something new. Explores local projects for reusable code, researches competitors, reads forums and reviews, analyses plugin ecosystems, investigates technical options, and produces a comprehensive research brief. Three depths: focused (30 min), wide (1-2 hours), deep (3-6 hours). Triggers: 'research this', 'discovery', 'explore the space', 'what should I build', 'competitive analysis', 'before I start building', 'research before coding'. Not for cited fact-checking research reports (a separate harness does those); this is pre-build product discovery.
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jezweb/claude-skills☆ 1.1KUpdated Oct 9, 2026
Turning research artifacts into actionable PM insight. Customer interviews, user research notes, support ticket reviews, sales call transcripts, survey data, in-app feedback, all synthesized into the decisions they are meant to inform. The discipline of moving from raw discovery data to clear product direction without losing signal in the synthesis or fabricating insight that was not actually there. Triggers on research synthesis, customer interview synthesis, user research analysis, discovery readout, research insights, sales call analysis, support ticket analysis, qualitative data analysis. Also triggers when a team has done research but cannot turn it into decisions, when synthesis is producing pretty decks but no roadmap movement, or when an upcoming PM decision needs to be grounded in research already conducted.
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rampstackco/claude-skills☆ 981Updated Oct 19, 2026
Run upstream brand discovery covering audience research, competitive landscape, category dynamics, problem space, and positioning territory exploration. Use this skill at the very start of a brand or website project when the user needs to understand who they're for, who they compete with, what the audience actually needs, and where the brand could plausibly stand. Triggers on brand discovery, audience research, market research, competitive scan, category research, customer research, who is this for, who are we, positioning research, intake, kickoff. Also triggers when a creative brief is requested but the upstream inputs (audience, competitors, problem space) are not yet clear.
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rampstackco/claude-skills☆ 981Updated Oct 19, 2026
Continuous product discovery research operations — picking the method that fits the question, recruiting and screening participants, building interview guides, and scoring evidence into insights. Use when planning or running discovery.
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borghei/Claude-Skills☆ 960Updated Oct 7, 2026
WS-Discovery protocol scanner for discovering and enumerating ONVIF cameras and IoT devices on the network. Use when you need to discover ONVIF devices, cameras, or WS-Discovery enabled equipment on a network.
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BrownFineSecurity/iothackbot☆ 865Updated Jun 1, 2026
Guide ethical customer discovery and research synthesis, distinguishing direct observations from inferences, preventing leading interview questions, and tracking quote-to-insight provenance. (triggers: `product customer discovery`, `product research synthesis`)
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HoangNguyen0403/agent-skills-standard☆ 579Updated Oct 18, 2026
Use this skill before answering, planning, or editing any MSTest 3.x-to-4.x upgrade or post-upgrade failure. Triggers include "MSTest v4 breaking changes"; CS0507/CS0103/CS1061/CS1615; ExecuteAsync, CallerInfo, DisplayName, or custom TestMethodAttribute; ClassCleanupBehavior; ContainsKey; ThrowsExactly or ExpectedException; IsInstanceOfType out parameters; TestTimeout.Infinite; ManagedType; net6/net7 compatibility; TestCase.Id history; TestName in ClassInitialize; TreatDiscoveryWarningsAsErrors; discovery errors after a clean build; and MSTest.Sdk/MTP or vstest.console discovery changes. Do not use for v1/v2-to-v3 leftovers, framework conversion, runner-only migration, or a general .NET upgrade.
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managedcode/dotnet-skills☆ 490Updated Oct 20, 2026
Generates Records of Processing Activities automatically from IT system inventories including Active Directory, cloud service catalogs, API gateway logs, and database schemas. Covers automated field population, data flow discovery, and system-to-RoPA mapping. Activate for automated RoPA, system inventory, data discovery, auto-population, IT-driven records.
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mukul975/Privacy-Data-Protection-Skills☆ 314Updated Mar 17, 2026
Apply Rob Fitzpatrick's Mom Test discipline to customer interviews during PRD v1.0 Market Adoption. Triggers on requests to interview customers, run discovery calls, validate ideas with users, or when user asks "how do I interview customers?", "Mom Test", "Rob Fitzpatrick", "customer interview", "user research without lies", "talking to humans", "discovery conversation". Outputs CFD-* discovery entries with Mom Test-calibrated confidence.
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mattgierhart/PRD-driven-context-engineering☆ 181Updated Aug 31, 2026
Influencer Discovery workflow skill. Use this skill when the user needs Find and evaluate influencers for brand partnerships, verify authenticity, and track collaboration performance across Instagram, Facebook, YouTube, and TikTok and the operator should preserve the upstream workflow, copied support files, and provenance before merging or handing off.
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diegosouzapw/awesome-omni-skills☆ 162Updated Jul 8, 2026
Amazon product discovery and potential bestseller mining via Nexscope data. Triggered when users mention product mining, potential bestsellers, high-conversion product selection, click growth analysis, market growth opportunities, keyword-based product selection, FBA profit screening, niche market product discovery, seller origin filtering, Nexscope data, FBA profitability screening, keyword-based product selection. Even if users do not explicitly mention "Nexscope", this skill should be triggered whenever the task involves keyword-driven Amazon product selection based on conversion rates, click volume, and profitability metrics.
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nexscope-ai/nexscope-ecommerce-skills☆ 96Updated Oct 15, 2026
Nexscope keyword expansion tool that expands a seed keyword into a list of related keywords with search volume, trends, PPC bids, ranking difficulty, and other metrics, covering 10 Amazon marketplaces including US, UK, DE, JP, etc. Trigger when the user mentions keyword expansion, keyword mining, long-tail keyword mining, related keywords, keyword suggestions, keyword discovery, PPC bid research, keyword competition, keyword discovery, Nexscope keywords, keyword expansion, keyword discovery, keyword scout, related keywords, long-tail keywords, keyword suggestions, PPC bid research, keyword competition, seed keyword expansion, keyword mining. Even if the user does not explicitly mention "Nexscope", if their need involves finding more related keywords and their search volume, competition, and other metrics starting from a seed keyword, this skill should also be triggered.
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nexscope-ai/nexscope-ecommerce-skills☆ 96Updated Oct 15, 2026
🇺🇸 User Interview & Cold-Start Operations Playbook — Battle-tested framework from HeyGen's 937 interviews to PMF. Complete SOP for user screening, interview execution, Beta testing methodology, cold-start user operations, churn analysis, and user grading systems. 🇨🇳 用户访谈与冷启动运营实战手册 — 基于 HeyGen 937 场访谈验证的 PMF 方法论。包含用户筛选、访谈执行、Beta 测试设计、冷启动用户运营、流失分析、用户分级体系完整 SOP。 🇯🇵 ユーザーインタビュー&コールドスタート運営プレイブック — HeyGenの937回インタビューで検証されたPMF方法論。ユーザースクリーニング、インタビュー実行、Betaテスト設計、コールドスタートユーザー運営、離脱分析、ユーザーグレーディング。 🇰🇷 사용자 인터뷰 & 콜드 스타트 운영 플레이북 — HeyGen 937회 인터뷰로 검증된 PMF 방법론. 사용자 스크리닝, 인터뷰 실행, Beta 테스트 설계, 콜드 스타트 사용자 운영, 이탈 분석, 사용자 등급 시스템. Triggers: "user interview" | "user research" | "customer discovery" | "PMF" | "product-market fit" | "beta test" | "beta testing" | "cold start users" | "cold start operations" | "churn analysis" | "user grading" | "用户访谈" | "用户调研" | "冷启动" | "冷启动运营" | "Beta测试" | "流失分析" | "用户分级"
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Gingiris-1031/gingiris-skills☆ 86Updated Oct 15, 2026
Deprecated alias. This skill was renamed to `deepline-scoring`. Use when a user or script still invokes `/niche-signal-discovery`: immediately load and follow the `deepline-scoring` skill instead. Triggers: ICP analysis, niche signals, won vs lost analysis, differential signals, signal discovery, ICP signal report, account scoring signals, lead scoring, first-party signals, buyer signals.
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getaero-io/gtm-eng-skills☆ 69Updated Oct 21, 2026
Use when starting a new feature, gathering requirements for an unfamiliar domain, refining a vague idea into actionable scope, or when a user request is ambiguous or underspecified. Conducts SAM Stage 1 discovery — structured requirements gathering through user discussion, asking WHO/WHAT/WHEN/WHY and never HOW. Produces the ARTIFACT:DISCOVERY document containing feature requirements, NFRs, goals, anti-goals, references, and resolved questions. Supports backlog item self-initialization via a
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Jamie-BitFlight/claude_skills☆ 67Updated Oct 20, 2026
Разговор-распаковка неудовлетворённостей (discovery-стратегирование). Сократический разбор сырой рефлексии и заметок на триаду Проблема/Неудовлетворённость/Эмоция → состояние пилота → приоритеты месяца (WHAT/WHY). Роль R1 Стратег, метод DP.METHOD.053. Триггеры — «разбери неудовлетворённости», «помоги со стратегией месяца», «что для меня сейчас важно», «/discovery-session».
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TserenTserenov/FMT-exocortex-template☆ 63Updated Oct 21, 2026
Strategic product leadership guidance for SaaS and technology companies. Covers product strategy, roadmap planning, product discovery, user research, growth product management, platform strategy, product analytics, and product launches. Use when defining product vision, prioritizing features, conducting discovery, analyzing metrics, or launching products. Use for "product strategy", "roadmap planning", "feature prioritization", "product discovery", "product metrics", "PRD writing".
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ncklrs/startup-os-skills☆ 52Updated Feb 27, 2026
Audit and repair Claude Code discovery symlinks for skills, agents, and teams. Compares registries against .claude/ directories at project and global levels, detects missing, broken, and extraneous symlinks, distinguishes almanac content from external projects, and optionally repairs gaps. Use after adding new skills or agents, after a repository rename or move, when slash commands stop working, or as a periodic health check.
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pjt222/agent-almanac☆ 42Updated Oct 21, 2026
Eliciting and documenting a sales process before it is built in Salesforce: stage sequencing, entry/exit criteria per stage, win/loss analysis requirements, and stage transition rules. Trigger keywords: sales process design, stage discovery, entry criteria, exit criteria, stage gate, win/loss categorisation, sales methodology, pipeline stages, opportunity stage mapping, stage ladder, probability ladder, forecast category mapping, required fields per stage, stage swim lane, discovery workshop, handoff brief. NOT for configuring OpportunityStage, Sales Processes or Path in Setup — use admin/opportunity-management. NOT for cross-functional swim-lane maps — use admin/process-flow-as-is-to-be.
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PranavNagrecha/AwesomeSalesforceSkills☆ 20Updated Oct 21, 2026
Use this skill when configuring FSC financial planning objects, designing periodic review cycles, modeling risk assessment workflows, or tracking goal progress in Financial Services Cloud. Trigger keywords: FinancialGoal, FinancialPlan, goal tracking, risk tolerance, review cycle, financial planning workflow, Discovery Framework, Revenue Insights. NOT for wealth management process discovery — use admin/wealth-management-requirements. NOT for Action Plan template mechanics — use admin/fsc-action-plans.
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PranavNagrecha/AwesomeSalesforceSkills☆ 20Updated Oct 21, 2026
Drafts California Superior Court discovery verification pages under CCP §§ 2030.250 and 2031.250 with proper CCP § 2015.5 perjury declarations. Trigger when the user needs a verification page for interrogatory or inspection/RPD responses, mentions California discovery verification, party vs. attorney signing, information-and-belief clauses, or fixing unverified responses. CA Superior Court only — not federal.
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CSlawyer1985/legal-skillhub☆ 19Updated Sep 23, 2026
Automated discovery and matching of agent skills for dynamic task routing and capability assessment
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curiositech/windags-skills☆ 16Updated Oct 19, 2026
Controls error rates across thousands of simultaneous tests in genomics discovery using false-discovery-rate methods (Benjamini-Hochberg 1995; Benjamini-Yekutieli 2001 for arbitrary dependence; Storey q-value with pi0 estimation; local FDR; independent filtering Bourgon 2010; covariate-weighted FDR via IHW Ignatiadis 2016), plus family-wise error control (Bonferroni, Holm) and the GWAS genome-wide threshold. Covers the FDR-versus-FWER choice as the discovery-versus-confirmatory distinction, the dependence assumptions behind BH (PRDS) versus BY, pi0 estimation, the independent-filtering and false-coverage-rate traps, and reproducibility ranking via IDR (Li 2011). Use when correcting p-values from genome-wide tests, choosing between BH/BY/q-value/Bonferroni, setting an FDR threshold, applying IHW or independent filtering, or interpreting q-values. For confirmatory trials with few pre-specified endpoints (closed testing, graphical/gatekeeping), see clinical-biostatistics/multiplicity-graphical.
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lilinji/GeneTind-Life-Skills☆ 15Updated Aug 21, 2026