Results for “replication”

Best practices for building and maintaining applications with PowerSync: Cloud and self-hosted setup, sync configuration, client SDK usage, backend integration (Supabase, custom Postgres, MongoDB, Azure DocumentDB, MySQL, MSSQL), schema changes, watch and reactive queries (useQuery), attachments, the upload queue, and debugging. Use this skill whenever the user mentions PowerSync, a @powersync/* package (@powersync/web, @powersync/react-native, @powersync/node), the powersync Flutter/Dart package, the powersync Rust crate, wa-sqlite, offline-first sync, local-first architecture, sync rules, sync streams, uploadData, fetchCredentials, disconnectAndClear, logout or user switching in a synced app, real-time data replication, Electric Cloud migration, Electric Shapes, an app stuck on Syncing, data not syncing, or wants to add offline-capable sync to a mobile or web app, even if they do not explicitly name PowerSync.

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Analyzes time-series and longitudinal RNA-seq for differential expression and trajectory structure. Covers DESeq2 LRT with reduced models, time as factor vs continuous vs natural splines, maSigPro (Nueda 2014 for RNA-seq), ImpulseDE2 with explicit impulse-model failure modes, DREAM for repeated measures via linear mixed models, pseudoreplication avoidance, conditional vs marginal modeling, and trajectory clustering with DPGP, Mfuzz (with Schwämmle 2010 fuzzifier estimation), and splines+k-means. Use when modeling time-course or longitudinal expression, choosing factor vs spline, handling repeated measures from the same subject, avoiding pseudoreplication, clustering temporal trajectories, or selecting between dedicated time-course tools and pairwise+LRT.

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Expert-level distributed systems theory covering consistency models, consensus algorithms, fault tolerance, replication, distributed transactions, and the CAP theorem.

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Expert-level molecular biology knowledge. Use when working with DNA replication, transcription, translation, gene regulation, cloning, PCR, sequencing, CRISPR, epigenetics, or molecular techniques. Also use when the user mentions 'DNA replication', 'transcription', 'translation', 'gene expression', 'PCR', 'cloning', 'restriction enzyme', 'gel electrophoresis', 'Western blot', 'CRISPR', 'epigenetics', 'promoter', 'enhancer', or 'RNA splicing'.

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Detect DCSync attacks where adversaries abuse Active Directory replication privileges to extract password hashes by monitoring for non-domain-controller accounts requesting directory replication via DsGetNCChanges.

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Create a MySQL CDC capture using flowctl with binlog replication. Use when setting up streaming from MySQL, Amazon RDS MySQL, or Aurora MySQL. Use when user says "capture MySQL", "stream from MySQL", "MySQL CDC", "binlog replication", or "connect MySQL to Estuary".

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Expert en bases de données (PostgreSQL, MySQL, MongoDB, Redis, query optimization, replication)

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Detect DCSync attacks where adversaries abuse Active Directory replication privileges to extract password hashes by monitoring for non-domain-controller accounts requesting directory replication via DsGetNCChanges.

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Compare cell-type composition and spatial features across conditions in IMC/MIBI cohorts with the patient as the experimental unit, covering pseudoreplication, per-patient aggregation, mixed models, compositional (Dirichlet/scCODA) differential abundance, diffcyt, per-image-to-patient spatial differential testing (SpaceANOVA), batch covariates, and FDR. Use when testing whether a cell type or spatial niche differs between groups, avoiding cell-level pseudoreplication, choosing a differential-abundance method, or correctly powering an IMC cohort comparison.

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Analyzes time-series and longitudinal RNA-seq for differential expression and trajectory structure. Covers DESeq2 LRT with reduced models, time as factor vs continuous vs natural splines, maSigPro (Nueda 2014 for RNA-seq), ImpulseDE2 with explicit impulse-model failure modes, DREAM for repeated measures via linear mixed models, pseudoreplication avoidance, conditional vs marginal modeling, and trajectory clustering with DPGP, Mfuzz (with Schwämmle 2010 fuzzifier estimation), and splines+k-means. Use when modeling time-course or longitudinal expression, choosing factor vs spline, handling repeated measures from the same subject, avoiding pseudoreplication, clustering temporal trajectories, or selecting between dedicated time-course tools and pairwise+LRT.

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Diagnose and fix common AEM 6.5 LTS replication issues including blocked queues, connectivity failures, and content distribution problems

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Orchestrates end-to-end replication workflows spanning multiple concerns: new environment setup, production incident response, and performance optimization for AEM 6.5 LTS.

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Use when publishing, unpublishing, replicating, or activating/deactivating content in AEM 6.5 LTS. Covers Quick Publish, Manage Publication, tree activation, bulk content activation, package replication, workflow-based approval, scheduled activation/deactivation (on/off time), dispatcher flush, and the programmatic Replication Java API for AEM publish instances.

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AEM as a Cloud Service content distribution and replication. Covers programmatic publishing using the Replication API and distribution event monitoring using Sling Distribution events.

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Compare cell-type composition and spatial features across conditions in IMC/MIBI cohorts with the patient as the experimental unit, covering pseudoreplication, per-patient aggregation, mixed models, compositional (Dirichlet/scCODA) differential abundance, diffcyt, per-image-to-patient spatial differential testing (SpaceANOVA), batch covariates, and FDR. Use when testing whether a cell type or spatial niche differs between groups, avoiding cell-level pseudoreplication, choosing a differential-abundance method, or correctly powering an IMC cohort comparison.

The English summary is being prepared. Showing the original description.

Analyzes time-series and longitudinal RNA-seq for differential expression and trajectory structure. Covers DESeq2 LRT with reduced models, time as factor vs continuous vs natural splines, maSigPro (Nueda 2014 for RNA-seq), ImpulseDE2 with explicit impulse-model failure modes, DREAM for repeated measures via linear mixed models, pseudoreplication avoidance, conditional vs marginal modeling, and trajectory clustering with DPGP, Mfuzz (with Schwämmle 2010 fuzzifier estimation), and splines+k-means. Use when modeling time-course or longitudinal expression, choosing factor vs spline, handling repeated measures from the same subject, avoiding pseudoreplication, clustering temporal trajectories, or selecting between dedicated time-course tools and pairwise+LRT.

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Detect DCSync attacks where adversaries abuse Active Directory replication privileges to extract password hashes by monitoring for non-domain-controller accounts requesting directory replication via DsGetNCChanges.

The English summary is being prepared. Showing the original description.

Diagnose and fix common AEM 6.5 LTS replication issues including blocked queues, connectivity failures, and content distribution problems

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Orchestrates end-to-end replication workflows spanning multiple concerns: new environment setup, production incident response, and performance optimization for AEM 6.5 LTS.

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Use when publishing, unpublishing, replicating, or activating/deactivating content in AEM 6.5 LTS. Covers Quick Publish, Manage Publication, tree activation, bulk content activation, package replication, workflow-based approval, scheduled activation/deactivation (on/off time), dispatcher flush, and the programmatic Replication Java API for AEM publish instances.

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Migrates legacy AEM (6.x, AMS, on-prem) to AEM as a Cloud Service using BPA CSV or cache, CAM/MCP target discovery, and a one-pattern-per-session workflow. Use for BPA/CAM findings, Cloud Service blockers, or fixes for scheduler, ResourceChangeListener, replication, EventListener, OSGi EventHandler, DAM AssetManager, HTL data-sly-test lint. OSGi configs → Cloud Manager — scan ui.config, .cfg.json, secrets, $[secret:]/$[env:] — agent follows references/osgi-cfg-json-cloud-manager.md when prompted. After BPA/CAM discovery, migration hands off each (pattern, file) pair to the code-assessment skill — code-assessment owns the five pattern guides (scheduler/, resource-change-listener/, replication/, event-migration/, asset-manager/) and the shared references for SCR→DS, ResourceResolver/SLF4J, HTL lint, and prerequisites.

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AEM as a Cloud Service content distribution and replication. Covers programmatic publishing using the Replication API and distribution event monitoring using Sling Distribution events.

The English summary is being prepared. Showing the original description.

Review MySQL and MariaDB database designs and production problems, including slow queries, locking, connection pools, and replica delays. Get concrete SQL or code changes and a validation plan that accounts for differences between engines and versions.

• Designing tables and indexes
• Investigating slow queries and deadlocks
• Reviewing migrations for large production tables

Implement and manage Raft, a method for keeping distributed servers in agreement. Covers leader election, log replication, node membership changes, and recovery after network disruptions to maintain consistent state across the cluster.

• Implementing leader election across distributed nodes
• Keeping replicated logs consistent
• Adding or removing cluster nodes