135 skills · sorted by relevance
Evaluate scientific claims and evidence quality. Use for assessing experimental design validity, identifying biases and confounders, applying evidence grading frameworks (GRADE, Cochrane Risk of Bias), or teaching critical analysis. Best for understanding evidence quality, identifying flaws. For formal peer review writing use peer-review.
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Structured manuscript/grant review with checklist-based evaluation. Use when writing formal peer reviews with specific criteria methodology assessment, statistical validity, reporting standards compliance (CONSORT/STROBE), and constructive feedback. Best for actual review writing, manuscript revision. For evaluating claims/evidence quality use scientific-critical-thinking; for quantitative scoring frameworks use scholar-evaluation.
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Evaluate scientific claims and evidence quality. Use for assessing experimental design validity, identifying biases and confounders, applying evidence grading frameworks (GRADE, Cochrane Risk of Bias), or teaching critical analysis. Best for understanding evidence quality, identifying flaws. For formal peer review writing use peer-review.
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Structured manuscript/grant review with checklist-based evaluation. Use when writing formal peer reviews with specific criteria methodology assessment, statistical validity, reporting standards compliance (CONSORT/STROBE), and constructive feedback. Best for actual review writing, manuscript revision. For evaluating claims/evidence quality use scientific-critical-thinking; for quantitative scoring frameworks use scholar-evaluation.
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Evaluate retrieval and citation behavior for RAG pipelines from deterministic JSONL fixtures. Use when an agent needs offline Recall@K, reciprocal rank, context precision, citation coverage, citation validity, diagnostics, Markdown/JSON reports, or threshold-gated evaluation in CI.
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Extract per-molecule embeddings from any encoder-bearing KERMT checkpoint. Use a local checkpoint or optionally download a pinned Hugging Face model bundle using HF_TOKEN if configured. Run containerized embedding extraction and write model bundles, per-readout .npy embeddings, canonical SMILES, and validity arrays to user-selected host directories.
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Evaluate research rigor. Assess methodology, experimental design, statistical validity, biases, confounding, evidence quality (GRADE, Cochrane ROB), for critical analysis of scientific claims.
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Evaluate scientific claims and evidence quality. Use for assessing experimental design validity, identifying biases and confounders, applying evidence grading frameworks (GRADE, Cochrane Risk of Bias), or teaching critical analysis. Best for understanding evidence quality, identifying flaws. For formal peer review writing use peer-review.
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Post-writing SEO validation with pass/fail checklist covering title tag length and keyword placement, meta description quality, heading hierarchy and keyword density, internal/external link audit with anchor text analysis, canonical URL verification, Open Graph meta tags (og:title, og:description, og:image), Twitter Card validation, structured data presence and validity, URL structure optimization, and image alt text presence. Produces prioritized fix list with specific recommendations. Use when user says "seo check", "check seo", "validate seo", "blog seo", "seo validation", "on-page seo", "title tag check", "meta description check", "heading check", "link audit".
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Post-writing SEO validation with pass/fail checklist covering title tag length and keyword placement, meta description quality, heading hierarchy and keyword density, internal/external link audit with anchor text analysis, canonical URL verification, Open Graph meta tags (og:title, og:description, og:image), Twitter Card validation, structured data presence and validity, URL structure optimization, and image alt text presence. Produces prioritized fix list with specific recommendations. Use for ONE finished post when the user says "seo check", "validate seo", "on-page seo", "title tag check", "link audit". Not for a whole-site audit (blog-audit, claude-seo), AI-citation scoring (blog-geo), schema generation (blog-schema), or the delivery gates (blog_preflight.py).
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Designs a structured real-world evidence study using EHR, claims, or registry data, with explicit handling of time zero, eligibility windows, exposure definitions, outcome windows, censoring, confounding control, and target-trial-emulation logic. Use this skill when the user needs study-type design and protocol framing for an observational clinical study based on routine-care data. Do not invent database fields, follow-up completeness, linkage, coding validity, or causal identifiability.
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Classify XQUIC GitHub issues with an evidence-backed L1-L4 resolution-complexity label while keeping validity, priority, severity, and disposition separate and skipping uniquely labeled issues unless the user explicitly forces a recheck. Use when triaging one issue or a batch of issues, creating an issue-complexity backlog, or applying or correcting L1-L4 GitHub labels.
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Use when asked 做一份外贸报价单, FOB 和 CIF 怎么报价, 出口报价核算, 报价怎么算利润, 退税怎么算进报价, quotation sheet for an export order, or price an export quotation from China. Produces a cost build-up from the factory price through export tax rebate, domestic logistics, port charges, freight and insurance to each Incoterms 2020 term, a quotation sheet in English with a Chinese summary, quantity tiers, validity and exchange-rate assumptions, payment terms and the risk each term puts on the seller, with rates marked to confirm.
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Use when the quantitative model is the bottleneck for an American Economic Journal: Macroeconomics (AEJ: Macro) manuscript — DSGE, New Keynesian, heterogeneous-agent (HANK / Aiyagari-Bewley), or structural estimation — and calibration, parameter identification, solution accuracy, or counterfactual validity need discipline. For empirical shock identification see aejmac-identification.
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Use when running and reporting the statistical analysis for an Academy of Management Journal (AMJ) manuscript — measurement validity, common-method bias, the right estimator (HLM, SEM, panel, experiments), endogeneity, and robustness. Executes and reports the analysis; it does not design the study (amj-methods) or frame the contribution (amj-contribution-framing).
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Use when the research design and method are the bottleneck for an Academy of Management Journal (AMJ) manuscript — matching design (archival, survey, experiment, multi-method, field) and level of analysis to the theoretical question. Designs the study; it does not run the estimation or validity checks (amj-data-analysis).
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Simulate transcription factor perturbation effects on cell state in silico with CellOracle and Dynamo, and predict transcriptional responses to genetic perturbations with GEARS, scGen, and CPA. Covers the direction-not-magnitude principle, local-linear validity, the GRN/velocity error it inherits, baseline discipline (mean and additive baselines), and the validation gap. Use when predicting TF knockout or overexpression effects, ranking driver TFs for fate transitions, or planning perturbation experiments. For GRN construction see multiomics-grn; for experimental Perturb-seq see single-cell/perturb-seq.
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Prioritizes rare-disease variants from trio/quad WES/WGS with de novo (DeNovoGear, Triodenovo), compound-heterozygous phasing (WhatsHap), mosaic VAF tiering, phenotype-driven ranking (Exomiser, Phen2Gene, AMELIE), ClinGen gene-disease validity gating, and ACMG SF v3.2 secondary findings reporting. Use when running diagnostic exome / genome pipelines, identifying candidate Mendelian disease genes, screening for incidental findings, or auditing VUS reclassification cycles. The ACMG/AMP classification framework (PVS1 decision tree, Pejaver PP3/BP4 calibration, Tavtigian point system) is in clinical-databases/acmg-classification.
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Validates docked / generated protein-ligand poses using PoseBusters physical-validity tests, strain energy quantification, geometric checks (planarity, vdW overlap, bond/angle distortion), and pose-energy reasonableness. Use when QC-ing docking results, comparing classical vs ML docking outputs, or filtering pose lists before SAR analysis.
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Estimates bivariate genetic correlation (rg) between traits from GWAS summary statistics or individual-level genotypes using cross-trait LDSC, HDL, LAVA, rho-HESS, GREML-bivariate, Popcorn, and HDL-L. Use when quantifying shared genetic architecture between two traits, screening MR validity before causal inference, distinguishing global from locus-level rg, estimating trans-ancestry rg, separating partial from full causation via LCV gcp, or producing a STROBE-MR-compliant cross-trait sensitivity battery. Cross-trait LDSC intercept absorbs sample overlap and is NOT a bias; HDL is biased under sample overlap above ~5%. High rg between exposure and outcome motivates CHP-aware MR sensitivity (CAUSE, LHC-MR).
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Expert TISAX (Trusted Information Security Assessment Exchange) advisor for the automotive supply chain — the ENX/VDA assessment regime that OEMs like VW, BMW, and Mercedes-Benz require from suppliers and service providers. Covers the VDA ISA 6 catalogue (current through 2026) and the ISA2027 transition (published July 1, 2026; mandatory for assessments ordered from January 1, 2027), assessment levels AL1/AL2/AL3, all 12 assessment objectives/labels (Confidential, Strictly Confidential, High/Very High Availability, Proto Parts/Vehicles, Test Vehicles, Proto Events, Data, Special Data), maturity scoring (0–5, target 3, cutback rules), the ENX portal process, scoping, audit-provider selection, corrective action plans and the 9-month window, 3-year label validity, and ISO 27001 mapping. Use for any TISAX, VDA ISA, ENX, automotive information-security assessment, prototype protection, or OEM supplier-security requirement question — gap assessments, label selection, readiness, and audit prep.
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Reviews or drafts the agreement that pays an employee to settle their claims — and flags the statutory conditions that decide whether it actually binds them. Works under s.203 ERA 1996 for England & Wales. Flags apparent s.203 condition gaps for a solicitor to confirm (writing, specific complaints, independent adviser, identification, insurance, statement of conditions), drafts the substantive terms (sum, tax characterisation, confidentiality, references, restrictive covenants, indemnities), and surfaces enforceability risks. Does not rule on validity and is not legal advice. Use when the user says 'review this settlement agreement', 'draft a settlement agreement', 'compromise agreement' (old term), or asks whether an agreement is binding.
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Performs a legal compliance audit for a Moroccan e-commerce website, focused on personal data protection (Law 09-08) and consumer contract disclosures/obligations (Law 31-08). Use this skill when a user asks to audit, check, or assess the legal compliance of an e-commerce website operating in Morocco — presence and validity of Terms & Conditions, privacy policy, CNDP declaration, mandatory disclosures, right of withdrawal, consent banner. Out of scope: compliance for other countries, Meta/Google advertising compliance (covered by another skill), definitive legal advice (results are a starting point for professional review, not legal advice).
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Maintain and update investment theses for A-share portfolio positions and watchlist names. Track key data points, catalysts, milestones, and thesis validity over time. Adapted from the original thesis-tracker skill for Chinese market conventions. Triggers on "A股持仓逻辑跟踪", "投资逻辑更新", "thesis check China", "update thesis for [company]", "is my thesis still intact", or "A股持仓复盘".
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