775 skills · sorted by relevance
Design AI ethics frameworks with principles, review processes, and governance. TRIGGERS - Use when user needs help with ai-ethics-framework related tasks.
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Design learning for adults using andragogy principles. TRIGGERS - Use when user needs help with adult-learning-design related tasks.
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Provides expert knowledge of the testing pyramid, test design principles, MockK patterns, and integration testing conventions for Spring Boot + Kotlin projects.
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Provides expert knowledge of the testing pyramid, test design principles, MockK patterns, and integration testing conventions for Spring Boot + Kotlin projects.
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Structures biological experiments so inference is valid by construction, covering Fisher's principles (randomization, replication, local control), the experimental-vs-observational unit distinction and pseudoreplication (Hurlbert 1984; Lazic 2018), randomization mechanics (complete, restricted, stratified, rerandomization, run-order), blocking layouts (randomized complete block, Latin square, incomplete block), factorial designs and interactions, and the split-plot/nested error strata hidden inside multi-batch genomics. Use when deciding the experimental unit and what counts as a replicate, planning randomization and run order, choosing a blocked/factorial/split-plot/nested layout, avoiding pseudoreplication in cell-culture or animal studies, or specifying the random-effects structure of the analysis model. For assigning samples to sequencing batches/lanes/plates and batch-effect correction see experimental-design/batch-design; for regulated clinical-trial randomization see clinical-biostatistics.
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Predicts ADMET properties using ADMETlab 3.0 (119 endpoints with uncertainty), ADMET-AI, DeepChem MolNet, and chemprop D-MPNN with explicit handling of OECD QSAR principles, applicability domain assessment, calibration, hERG/CYP/AMES gold-standard endpoints, and PAINS / Lipinski / Ro5 / Veber / BBB druglikeness filters. Use when filtering compounds for drug-likeness, prioritizing leads by predicted safety, or building an in-house ADMET QSAR model.
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Builds QSAR / QSPR models using chemprop D-MPNN, MolFormer, Uni-Mol, ChemBERTa, random forest baselines, and Gaussian processes with explicit handling of OECD 5 principles, applicability domain (kNN, leverage, conformal prediction, Mahalanobis), scaffold-balanced splits, ensemble uncertainty, calibration (Platt, isotonic), feature importance (SHAP, atomic attribution), and prospective validation. Use when building target-specific predictive models from in-house bioassay data, ADMET endpoints, or selectivity profiles.
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Refactor Spring Boot and Java code to improve maintainability, readability, and adherence to enterprise best practices. This skill transforms messy Spring Boot applications into clean, well-structured solutions following SOLID principles and Spring Boot 3.x conventions. It addresses fat controllers, improper transaction boundaries, field injection anti-patterns, and scattered configuration. Leverages Java 21+ features including record patterns, pattern matching for switch, virtual threads, and sequenced collections.
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Build production-grade Azure Cosmos DB NoSQL services following clean code, security best practices, and TDD principles.
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First-principles assumption auditor. Classifies each hidden assumption (fact / convention / belief / interest-driven), ranks by fragility × impact, and rebuilds conclusions from verified premises. Bilingual: auto-detects Chinese or English.
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API design principles and decision-making. REST vs GraphQL vs tRPC selection, response formats, versioning, pagination.
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Single Source of Truth (SSOT) guidelines for SwiftUI state management. Use when designing state architecture, choosing between @State/@Binding/@StateObject/@ObservedObject/@EnvironmentObject, fixing state synchronization issues, refactoring duplicated state, or reviewing state management in PRs. Covers SSOT principles, property wrapper selection, state lifting, and common violations.
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Extract and analyze Figma designs to create structured design specifications. Use this skill when you need to analyze Figma nodes, extract design properties (layout, spacing, typography), classify components using Atomic Design principles, and generate design specification documents that can be used for implementation.
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Apply continuous improvement principles to iteratively enhance processes, code quality, team practices, and system performance through small, incremental changes. Use when improving development processes, optimizing workflows, reducing waste, enhancing code quality over time, implementing retrospective learnings, or fostering a culture of continuous improvement.
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When the user wants to apply psychological principles, mental models, or behavioral science to marketing. Also use when the user mentions 'psychology,' 'mental models,' 'cognitive bias,' 'persuasion,' 'behavioral science,' 'why people buy,' 'decision-making,' 'consumer behavior,' 'anchoring,' 'social proof,' 'scarcity,' 'loss aversion,' 'framing,' or 'nudge.' Use this whenever someone wants to understand or leverage how people think and make decisions in a marketing context.
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Auto-review pipeline — reads the full CEO, design, eng, and DX review skills from disk and runs them sequentially with auto-decisions using 6 decision principles. Surfaces taste decisions (close approaches, borderline scope, codex disagreements) at a final approval gate. One command, fully reviewed plan out. Use when asked to "auto review", "autoplan", "run all reviews", "review this plan automatically", or "make the decisions for me". Proactively suggest when the user has a plan file and wants to run the full review gauntlet without answering 15-30 intermediate questions. (gstack) Voice triggers (speech-to-text aliases): "auto plan", "automatic review".
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Reference for writing and editing skills well — the vocabulary and principles that make a skill predictable.
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Derive and implement first-principles audio-coupled haptic and kinetic UI feedback. Use when designing, reviewing, or coding haptics/audio for mobile apps, native iOS/Android, React Native/Expo, SwiftUI, games, detent pickers, toggles, sliders, page curls, scroll gestures, wallet/signature flows, Solana transactions, backend/realtime state changes, confirmations, settlements, and semantic UI events where feedback should follow signal math instead of ad hoc vibration calls.
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Build production-grade Azure Cosmos DB NoSQL services following clean code, security best practices, and TDD principles.
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API design principles and decision-making. REST vs GraphQL vs tRPC selection, response formats, versioning, pagination.
The English summary is being prepared. Showing the original description.
Structures biological experiments so inference is valid by construction, covering Fisher's principles (randomization, replication, local control), the experimental-vs-observational unit distinction and pseudoreplication (Hurlbert 1984; Lazic 2018), randomization mechanics (complete, restricted, stratified, rerandomization, run-order), blocking layouts (randomized complete block, Latin square, incomplete block), factorial designs and interactions, and the split-plot/nested error strata hidden inside multi-batch genomics. Use when deciding the experimental unit and what counts as a replicate, planning randomization and run order, choosing a blocked/factorial/split-plot/nested layout, avoiding pseudoreplication in cell-culture or animal studies, or specifying the random-effects structure of the analysis model. For assigning samples to sequencing batches/lanes/plates and batch-effect correction see experimental-design/batch-design; for regulated clinical-trial randomization see clinical-biostatistics.
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Builds QSAR / QSPR models using chemprop D-MPNN, MolFormer, Uni-Mol, ChemBERTa, random forest baselines, and Gaussian processes with explicit handling of OECD 5 principles, applicability domain (kNN, leverage, conformal prediction, Mahalanobis), scaffold-balanced splits, ensemble uncertainty, calibration (Platt, isotonic), feature importance (SHAP, atomic attribution), and prospective validation. Use when building target-specific predictive models from in-house bioassay data, ADMET endpoints, or selectivity profiles.
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Predicts ADMET properties using ADMETlab 3.0 (119 endpoints with uncertainty), ADMET-AI, DeepChem MolNet, and chemprop D-MPNN with explicit handling of OECD QSAR principles, applicability domain assessment, calibration, hERG/CYP/AMES gold-standard endpoints, and PAINS / Lipinski / Ro5 / Veber / BBB druglikeness filters. Use when filtering compounds for drug-likeness, prioritizing leads by predicted safety, or building an in-house ADMET QSAR model.
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State-of-the-art data visualization for React/Next.js/TypeScript with Tailwind CSS. Creates compelling, tested, and accessible visualizations following Tufte principles and NYT Graphics standards. Activate on "data viz", "chart", "graph", "visualization", "dashboard", "plot", "Recharts", "Nivo", "D3". NOT for static images, print graphics, or basic HTML tables.
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