243 skills · sorted by relevance
Predict structures of protein, nucleic acid, and small-molecule complexes with ESMFold2, using single sequences or aligned related sequences. The skill also covers ESMC models for numerical sequence representations, mutation scoring, and predictions of contacts between residues.
Convert protein sequences into numerical features with Meta AI's ESM-2 for machine learning. Extract features for individual amino acids or whole sequences, score mutations, and predict which positions in a protein may contact each other.
Find and run over 2,000 AI models and API tools through one MCP connection, a shared interface for agents. Inspect inputs and pricing before generating media, searching the web, or retrieving structured and social data.
Prepare research papers for RAG, a method that supplies retrieved documents to AI. Download PDFs, extract and split text, and build a local searchable database, with parallel processing for document batches.
Search stored learnings from past sessions by meaning or keywords. Retrieve relevant entries in full, along with their type, confidence, and session context, to revisit earlier findings about development patterns, installation, or errors.
Selects, investigates, and compares AWS object, file, and block storage services, and answers cost, performance, configuration, security, and troubleshooting questions about storage services. Applies when a user asks where to store or archive data based on their usage patterns; which storage service to choose or how two compare; how to migrate data from on-premises or between AWS services; how to protect, replicate, or recover data; how to optimize storage costs; where to deploy shared NFS, SMB, or POSIX file systems; where to store vector embeddings or tabular data; what storage backs enterprise file shares, self-managed databases on EC2, VMware, or stateful containers; or asks what an AWS storage service can do or how it works. Relevant for storage needs for workloads such as AI/ML, analytics, EDA, HPC, media, genomics, or financial trading. Not applicable for SQL query engines (Athena, Spark, Redshift, EMR), ETL (Glue), streaming (Kafka, MSK, Kinesis), or managed database services (RDS, Aurora, DynamoDB).
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Designs, reviews, and debugs DynamoDB data layers from design axioms — enumerates access patterns, chooses partition/sort keys and GSIs, decides single-table vs. multi-table, configures Streams, Global Tables, TTL, vector indexes for similarity search, and zero-ETL integrations to OpenSearch/Redshift/SageMaker Lakehouse, and produces a defensible data-layer design with a monthly cost estimate and optional live validation. Applies whenever a user is designing, reviewing, or refactoring anything backed by DynamoDB — schemas, access patterns, GSIs, single- vs. multi-table choices, Streams consumers, transactional outboxes, Global Tables, zero-ETL pipelines, or storing embeddings and running semantic/vector similarity search with SearchVectors on items already in DynamoDB — even when they don't say "axioms" or "design review." Also applies when debugging hot partitions, throttling, unbounded Scans, LWW conflicts, or surprise bills on DynamoDB workloads.
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Set up, download, verify, and seed the optional Grida Library developer corpus into local Supabase. Use when Library browse/search, Desktop reference picking, or agent Library tools need realistic local assets and Gemini embeddings; also use when changing the gridaco/grida consumer for gridaco/library developer-corpus releases.
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Machine learning toolkit for genomic interval (BED) data; use it when you need to tokenize BED collections and train embeddings for regions/cells/labels, build consensus peak universes, or run similarity search and downstream ML on chromatin accessibility datasets.
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Use when performing sample-level dimensionality reduction and visualization on abundance or OTU-style matrices with a companion group file, generating UMAP and/or t-SNE coordinates and plots for group separation assessment. NOT for: differential expression testing, single-cell workflows requiring dedicated embeddings pipelines, or analyses without a sample grouping file.
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Use this skill for any PostgreSQL database work — table design, indexing, data types, constraints, extensions (pgvector, PostGIS, TimescaleDB), search, and migrations. **Trigger when user asks to:** - Explore an existing PostgreSQL database to understand its objects and relationships - Design or modify PostgreSQL tables, schemas, or data models - Choose data types, constraints, indexes, or partitioning strategies - Work with pgvector embeddings, semantic search, or RAG - Set up full-text search, hybrid search, or BM25 ranking - Use PostGIS for spatial/geographic data - Set up TimescaleDB hypertables for time-series data - Migrate tables to hypertables or evaluate migration candidates - Plan or execute safe schema migrations with zero downtime **Keywords:** PostgreSQL, Postgres, SQL, schema, table design, indexes, constraints, pgvector, PostGIS, TimescaleDB, hypertable, semantic search, hybrid search, BM25, time-series, migration
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Combine visual features (face detection, lip movement analysis) with audio features to improve speaker diarization accuracy in video files. Use OpenCV for face detection and lip movement tracking, then fuse visual cues with audio-based speaker embeddings. Essential when processing video files with multiple visible speakers or when audio-only diarization needs visual validation.
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Installs and configures ktx, the open-source context layer for data agents — runs ktx setup non-interactively with hidden CLI flags, configures database connections and embeddings, installs agent integration, and verifies readiness. Use when the user asks an agent to add ktx to a project, connect data sources, install agent rules, ingest schema, or troubleshoot a local ktx install.
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INVOKE THIS SKILL when building ANY retrieval-augmented generation (RAG) system. Covers document loaders, RecursiveCharacterTextSplitter, embeddings (OpenAI), and vector stores (Chroma, FAISS, Pinecone).
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Unsupervised clustering and cell-type identification for high-dimensional flow, spectral, and mass cytometry - FlowSOM, PhenoGraph, FlowSOM-via-CATALYST, with UMAP/tSNE for visualization. Covers the type-vs-state marker distinction (cluster on lineage, test state within clusters), over-provision-then-metacluster, the Weber-Robinson benchmark, seed dependence and metacluster stability, why embeddings are for looking not measuring, and median-heatmap annotation/merging. Use when discovering populations without predefined gates, choosing a clustering algorithm, selecting the number of metaclusters, or annotating clusters into cell types.
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Build publication-quality figures with matplotlib using the object-oriented Figure/Axes API, constrained_layout, rcParams customization, TrueType (Type-42) font embedding for journal submission, and CVD-safe palettes. Covers seaborn integration, common chart types, axis formatting, and the small gotchas that distinguish reproducible matplotlib from notebook scratch. Use when producing publication figures in Python — RNA-seq scatter, single-cell embeddings, generic biological plotting.
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Tokenize, tag, and analyze natural language text using Apple's NaturalLanguage framework and translate between languages with the Translation framework. Use when adding language identification, sentiment analysis, named entity recognition, part-of-speech tagging, text embeddings, or in-app translation to iOS/macOS/visionOS apps.
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Guides MongoDB users through implementing and optimizing Atlas Search (full-text), Vector Search (semantic), and Hybrid Search solutions. Use this skill when users need to build search functionality for text-based queries (autocomplete, fuzzy matching, faceted search), semantic similarity (embeddings, RAG applications), or combined approaches. Also use when users need text containment, substring matching ('contains', 'includes', 'appears in'), case-insensitive or multi-field text search, or filtering across many fields with variable combinations. Provides workflows for selecting the right search type, creating indexes, constructing queries, and optimizing performance using the MongoDB MCP server.
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AWS Bedrock foundation models for generative AI. Use when invoking foundation models, building AI applications, creating embeddings, configuring model access, or implementing RAG patterns.
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Search all Japanese NLP resources (libraries, models, datasets, tutorials, dictionaries, Hugging Face). Accepts keywords or natural language questions in any language. Use whenever the user asks which Japanese NLP resource to use, or wants to find one: tokenizers / morphological analyzers, BERT or LLM models, embeddings, NER, text classification, datasets / corpora, dictionaries, tutorials, or Hugging Face models. Trigger phrases include '日本語の形態素解析ライブラリ', 'おすすめの日本語tokenizer', '日本語BERTモデル', '日本語の感情分析データセット', '日本語LLM 一覧', 'which Japanese embedding model', 'Japanese NER library'.
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Use when writing test fixtures for @copilotkit/aimock — mock LLM responses, tool call sequences, error injection, multi-turn agent loops, embeddings, structured output, sequential responses, or debugging fixture mismatches
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Use when the user sends or generates an image, screenshot, video, audio or file and wants it saved, or asks to find past media (that diagram, the mockup from last week). Ingests and searches with local ChromaDB embeddings.
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Use when implementing GPT chat, streaming, function calling, embeddings for RAG, images, audio or batch jobs, or troubleshooting 429 rate limits and API or TypeScript errors. Stateless OpenAI patterns that prevent 16 documented errors.
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RAG-specific best practices for LlamaIndex, ChromaDB, and Celery workers. Covers ingestion, retrieval, embeddings, and performance.
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