Expert-level materials informatics covering materials databases, machine learning for property prediction, high-throughput computation, and data-driven materials discovery.
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Expert-level materials informatics covering materials databases, machine learning for property prediction, high-throughput computation, and data-driven materials discovery.
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This skill covers deploying anomaly detection systems for industrial control environments using machine learning models trained on OT network baselines, physics-based process models, and behavioral analysis of industrial protocol communications. It addresses building normal behavior profiles for SCADA polling patterns, detecting deviations in Modbus/DNP3/OPC UA traffic, identifying rogue devices, and correlating network anomalies with physical process data from historians.
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Machine learning development with JAX, functional programming patterns, and high-performance computing.
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This skill covers deploying anomaly detection systems for industrial control environments using machine learning models trained on OT network baselines, physics-based process models, and behavioral analysis of industrial protocol communications. It addresses building normal behavior profiles for SCADA polling patterns, detecting deviations in Modbus/DNP3/OPC UA traffic, identifying rogue devices, and correlating network anomalies with physical process data from historians.
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Validates predictive models on omics and biomedical data with nested cross-validation, group/batch/temporal-aware splits, the full data-leakage taxonomy, probability calibration, decision-curve net benefit, optimism correction, sample-size planning, and TRIPOD+AI reporting. Use when estimating model performance honestly, choosing a CV scheme, detecting leakage, or judging whether reported discrimination means the model is actually useful. For feature selection itself see machine-learning/biomarker-discovery; for confirmatory-trial inference see clinical-biostatistics/trial-reporting.
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Decision-grade statistical analysis for metabolomics intensity tables. Covers transformation and scaling (Pareto vs unit-variance as a hidden hypothesis), unsupervised structure (PCA/HCA for QC), permutation-validated PLS-DA/OPLS-DA (R2 vs Q2, double CV, VIP as heuristic), univariate testing (Welch/Mann-Whitney/ANOVA/LMM with covariate adjustment), and dependence-aware multiple testing. Use when testing which metabolites differ, building or validating a discriminant model, choosing a scaling, or correcting many correlated tests. For sample-wise normalization/drift correction see metabolomics/normalization-qc; for ML classifiers and selection-inside-CV leakage see machine-learning/biomarker-discovery and machine-learning/model-validation; for pathway interpretation see metabolomics/pathway-mapping; for design/power/multiplicity regime see experimental-design/multiple-testing.
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This skill covers deploying anomaly detection systems for industrial control environments using machine learning models trained on OT network baselines, physics-based process models, and behavioral analysis of industrial protocol communications. It addresses building normal behavior profiles for SCADA polling patterns, detecting deviations in Modbus/DNP3/OPC UA traffic, identifying rogue devices, and correlating network anomalies with physical process data from historians.
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Build game systems in Godot 4 using GDScript patterns for player movement, health, event signals, and scene organization. Use the architectural guidance to plan game state management and performance improvements while learning practical coding conventions.
Configure machine learning training and batch jobs across multiple clouds with SkyPilot. The skill guides GPU selection, lower-cost cloud and region choices, and automatic recovery when discounted spot instances are interrupted.
Build data processing pipelines for machine learning, from preprocessing to batch predictions. Uses Ray Data to handle datasets larger than memory, distribute work across CPUs and GPUs, and feed data into training frameworks.
Configure machine learning training and batch jobs across multiple clouds with SkyPilot. The skill guides GPU selection, lower-cost cloud and region choices, and automatic recovery when discounted spot instances are interrupted.
Build data processing pipelines for machine learning, from preprocessing to batch predictions. Uses Ray Data to handle datasets larger than memory, distribute work across CPUs and GPUs, and feed data into training frameworks.
Answer Python questions and write code using examples fetched from pythonsheets.com. Find patterns for syntax, asynchronous tasks, networking, databases, machine learning, and distributed computing, or use topic-based questions to prepare for Python interviews.
Select technologies for AI and machine learning features in .NET 8+ applications. Get task-specific plans or implementation guidance for structured predictions, text generation, document retrieval, tool-using agents, and running pretrained models locally or in production.
Build a reproducible Stata analysis from data cleaning through modeling, diagnostic checks, and robustness tests. Generate runnable .do files, regression tables, and figures for empirical papers, with additional workflows for epidemiology and machine learning approaches to causal inference.
Train, deploy, and run predictions with neural networks using Flow Nexus and E2B sandboxes, isolated computing environments. Use existing model templates, distribute training across multiple environments, and check training progress and model performance.
Model interpretability and explainability using SHAP (SHapley Additive exPlanations). Use this skill when explaining machine learning model predictions, computing feature importance, generating SHAP plots (waterfall, beeswarm, bar, scatter, force, heatmap), debugging models, analyzing model bias or fairness, comparing models, or implementing explainable AI. Works with tree-based models (XGBoost, LightGBM, Random Forest), deep learning (TensorFlow, PyTorch), linear models, and any black-box model.
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Comprehensive healthcare AI toolkit for developing, testing, and deploying machine learning models with clinical data. This skill should be used when working with electronic health records (EHR), clinical prediction tasks (mortality, readmission, drug recommendation), medical coding systems (ICD, NDC, ATC), physiological signals (EEG, ECG), healthcare datasets (MIMIC-III/IV, eICU, OMOP), or implementing deep learning models for healthcare applications (RETAIN, SafeDrug, Transformer, GNN).
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Review candidate learnings in Claude Code's native auto memory (`~/.claude/projects/<project>/memory/`, machine-local) and run them through a five-critic council in parallel: generality, staleness, redundancy, evidence, format. Majority vote (3+ of 5) promotes the entry to MEMORY.md. Use when user says "promote memory", "review my learnings", "what should graduate to MEMORY.md", "five-critic council", or as monthly memory maintenance.
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Train and deploy neural networks in distributed E2B sandboxes with Flow Nexus
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Train and deploy neural networks in distributed E2B sandboxes with Flow Nexus
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Classical ML in Python: classification, regression, clustering, dim reduction, evaluation, tuning, preprocessing pipelines. Linear models, tree ensembles, SVMs, K-Means, PCA, t-SNE. Use PyTorch/TF for deep learning; XGBoost/LightGBM for scale.
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Use DeepXDE for scientific machine learning, PINNs, DeepONet/operator learning, backend selection, training, and troubleshooting.
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Maps query single-cell data to reference atlases using scArches transfer learning with scVI and scANVI models. Transfers cell type labels without retraining on combined data. Use when annotating new single-cell datasets using pre-trained reference models.
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