272 skills · sorted by relevance
Analyze genomic regions with gtars using Python or command-line tools. Find overlaps, generate coverage tracks showing read density, prepare regions as tokens for machine learning, and split single-cell fragment data for further analysis.
Analyze stocks with Mark Minervini's SEPA (Specific Entry Point Analysis) methodology: stage analysis, the 8-condition trend template, fundamentals, VCP and other base patterns, pivot-point entries, market environment, and risk-based position sizing. Use this skill whenever the user mentions SEPA, Minervini, superperformance, the trend template, VCP (volatility contraction pattern), Stage 2, pivot or breakout entries, moving-average stacking (price above the 50/150/200-day MAs), breakout volume, position sizing from risk percentage, growth-stock screening or swing-trade entry criteria, or bases such as cup-with-handle, flat base, bull flag, or high tight flag. Also use it when the user asks "should I buy this stock" or "is this a good setup" about a growth or momentum name, or shares a chart for pattern analysis.
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Current-era minimalist design with bento grids, dark mode support, and high-performance accessible layouts.
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Read biological sequence files (FASTA, FASTQ, GenBank, EMBL, ABI, SFF) using Biopython Bio.SeqIO. Use when parsing sequence files, iterating multi-sequence files, random access to large files, or high-performance parsing.
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Postgres best practices maintained by Supabase, for Postgres running anywhere. Load this skill BEFORE writing or changing anything that lives in a Postgres database: creating or altering tables and columns (including choosing column types), schema design, migrations and declarative schema files, RLS policies and the tests that verify them, indexes, triggers, database functions, queues and scheduled jobs (pg_cron, pgmq), vector/semantic search (pgvector), and restoring dumps (pg_restore) or importing data. Also load it when diagnosing slow queries, high CPU, timeouts, EXPLAIN plans, connection exhaustion, locking, bloat, or rows visible to the wrong user or tenant. This is not just a performance guide — schema, migration, security, and SQL authoring tasks need these rules too, even for a one-column change or a single query.
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Execute incident response procedures for Claude API outages and degradation. Use when Claude API is returning errors, experiencing high latency, or showing degraded performance in production. Trigger with phrases like "anthropic incident", "claude api down", "anthropic outage", "claude degraded", "anthropic runbook".
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Design motivation systems using Autonomy, Mastery, and Purpose (AMP) for products and teams. Use when the user mentions "intrinsic motivation", "gamification isnt working", "rewards arent working", "autonomy", "mastery", "purpose-driven", "my team is disengaged", or "how do I motivate people". Also trigger when designing onboarding progression, fixing broken gamification, or building team structures that sustain high performance. Covers why carrot-and-stick fails and how to build progress systems. For habit-forming product loops, see hooked-ux. For retention behavior design, see improve-retention.
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ClickHouse database patterns, query optimization, analytics, and data engineering best practices for high-performance analytical workloads.
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A high-performance Rust toolkit (with Python bindings and a CLI) for genomic interval analysis; use it when you need fast overlap queries, coverage track generation, genomic tokenization for ML, reference sequence verification, or fragment processing.
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Use when evaluating crypto investments through a Multicoin-style thesis lens: high-conviction sector bets, performance chains, token value capture, and crypto-native market structure.
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High-performance numerical computing and machine learning workflows using JAX. Supports array operations, automatic differentiation, JIT compilation, RNN-style scans, map/reduce operations, and gradient computations. Ideal for scientific computing, ML models, and dynamic array transformations.
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Work with Rust async runtimes — Tokio, async-std, executor internals, pinning, wakers, and building high-performance async Rust services.
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Write idiomatic PHP code with generators, iterators, SPL data structures, and modern OOP features. Use PROACTIVELY for high-performance PHP applications.
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Build high-performance async APIs with FastAPI, SQLAlchemy 2.0, and Pydantic V2. Master microservices, WebSockets, and modern Python async patterns. Use PROACTIVELY for FastAPI development, async optimization, or API architecture.
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Configure secure, high-performance connectivity between on-premises infrastructure and cloud platforms using VPN and dedicated connections. Use when building hybrid cloud architectures, connecting data centers to cloud, or implementing secure cross-premises networking.
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Expert database administrator specializing in modern cloud databases, automation, and reliability engineering. Masters AWS/Azure/GCP database services, Infrastructure as Code, high availability, disaster recovery, performance optimization, and compliance. Handles multi-cloud strategies, container databases, and cost optimization. Use PROACTIVELY for database architecture, operations, or reliability engineering.
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Master Python asyncio, concurrent programming, and async/await patterns for high-performance applications. Use when building async APIs, concurrent systems, or I/O-bound applications requiring non-blocking operations.
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Intelligent network quality analysis with adaptive loading strategies. Detects connection type (2g/3g/4g), bandwidth, RTT, and save-data mode, then automatically triggers appropriate optimization workflows. Includes decision trees that recommend image compression for slow connections, critical CSS inlining for high RTT, and save-data optimizations (disable autoplay, reduce quality). Features connection-aware performance budgets (500KB for 2g, 1.5MB for 3g, 3MB for 4g+) and adaptive loading implementation guides. Cross-skill integration with Loading (TTFB impact), Media (responsive images), and Core Web Vitals (connection impact on LCP/INP). Use when the user asks about slow connections, mobile optimization, save-data support, or adaptive loading strategies. Compatible with Chrome DevTools MCP.
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Help users design and execute a high-signal interview process that prioritizes real-world performance over superficial charisma or pedigree.
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ClickHouse database patterns, query optimization, analytics, and data engineering best practices for high-performance analytical workloads.
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Write modern, high-performance C# code using records, pattern matching, value objects, async/await, Span<T>/Memory<T>, and best-practice API design patterns. Emphasizes functional-style programming with C# 12+ features.
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Via modeling: pads, antipads, ground return vias, GRV placement, and signal integrity for high-speed layer transitions. TRIGGER: user asks to model a via, design a via transition, place ground return vias, analyze via performance, or check signal integrity through layer transitions. Invoke BEFORE writing code — only viaSingleEnded exists (no viaDifferential), and the location format is non-obvious. SKIP: general signal integrity without vias (use matlab-analyze-em), transmission line design (use matlab-design-pcb-transmission-line), PDN analysis (use matlab-analyze-pcb-pdn), material/stackup setup only (use matlab-manage-pcb-material).
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Postgres best practices maintained by Supabase, for Postgres running anywhere. Load this skill BEFORE writing or changing anything that lives in a Postgres database: creating or altering tables and columns (including choosing column types), schema design, migrations and declarative schema files, RLS policies and the tests that verify them, indexes, triggers, database functions, queues and scheduled jobs (pg_cron, pgmq), vector/semantic search (pgvector), and restoring dumps (pg_restore) or importing data. Also load it when diagnosing slow queries, high CPU, timeouts, EXPLAIN plans, connection exhaustion, locking, bloat, or rows visible to the wrong user or tenant. This is not just a performance guide — schema, migration, security, and SQL authoring tasks need these rules too, even for a one-column change or a single query.
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Optimize MongoDB client connection configuration (pools, timeouts, patterns) for any supported driver language. Use this skill when working/updating/reviewing on functions that instantiate or configure a MongoDB client (eg, when calling `connect()`), configuring connection pools, troubleshooting connection errors (ECONNREFUSED, timeouts, pool exhaustion), optimizing performance issues related to connections. This includes scenarios like building serverless functions with MongoDB, creating API endpoints that use MongoDB, optimizing high-traffic MongoDB applications, creating long-running tasks and concurrency, or debugging connection-related failures.
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