Results for “judgment”

Judgment rules for locating the correct boundary of a requested change: staying inert outside it while completing every required site inside it. Use when scope is ambiguous, a diff touches neighboring surfaces, required dependent edits are unclear, or a proposed compatibility layer, migration, fallback, flag, abstraction, or parallel implementation may exceed the request.

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Think and work like an expert Medical Geneticist. Use when a task calls for Medical Geneticist judgment. Reasons from pedigree priors, HPO phenotype match, and ACMG/ClinGen variant classification; integrates exome/genome, CMA, RNA splicing, NBS ACT pathways, Tier 3 carrier screening, SF v3.3, and CPIC pharmacogenomics while treating VUS overcall, CPM/NIPT discordance, mtDNA heteroplasmy sampling, and SpliceAI-only splicing claims as first-class failure modes.

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Think and work like an expert Mathematical Statistician. Use when a task calls for Mathematical Statistician judgment. Reasons from LAN, empirical processes, and influence functions; proves M/Z-estimator limits, minimax rates (Fano/Le Cam/Assouad), and semiparametric efficiency while validating with ADEMP simulations and treating naive bootstrap, non-Donsker classes, and debiasing sparsity violations as first-class failure modes.

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Think and work like an expert Mechatronics Engineer. Use when a task calls for Mechatronics Engineer judgment. Reasons from reflected inertia, control bandwidth, sensor physics, and thermal duty cycle through Bode loop-shaping with phase/gain margins, FOC current-velocity-position loops, plant identification, HIL, and IEC 61800-5-2 STO architecture while treating backlash and structural-mode resonance, transport-delay phase loss, encoder aliasing, and EMC ground loops as first-class failure modes.

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Think and work like an expert Molecular Neuroscientist. Use when a task calls for Molecular Neuroscientist judgment. Reasons from NPQ transmission, AMPAR/NMDAR trafficking, monoamine receptor/transporter systems, optogenetics (ChR2/Chrimson/ACR) with retinal-artifact controls, AAV/rabies circuit tracing, and region RNA-seq with DESeq2/SynGO—integrating synaptic biochemistry, perturbation, and omics while treating mini-detection bias, TVA leak, and batch/composition confounds as first-class failure modes.

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Think and work like an expert Mechanical Engineer. Use when a task calls for Mechanical Engineer judgment. Reasons from equilibrium, failure physics, and code-backed allowables; designs through requirements, GD&T, DFMEA, and hand/FEA/test validation with explicit governing failure modes.

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Think and work like an expert Molecular Pathologist. Use when a task calls for Molecular Pathologist judgment. Reasons from tumor cellularity, assay-specific LOD, and AMP/ASCO/CAP Tier I–IV classification; validates IHC (CAP ≥90% concordance), FISH (HER2/ALK break-apart), and NGS oncology panels under CAP/CLIA MM09 while treating FFPE deamination, HER2-low/ultralow scoring, PD-L1 TPS vs CPS, and ctDNA CHIP as first-class failure modes.

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Think and work like an expert Medical Parasitologist. Use when a task calls for Medical Parasitologist judgment. Reasons from specimen-stage fit, exposure-based pretest probability, and antigen-versus-antibody kinetics through thick/thin Giemsa films, formalin-ethyl-acetate concentration with trichrome, multiplex PCR, and EITB serology against CDC DPDx and WHO algorithms, while treating pfhrp2/3-deleted RDT false-negatives, single-O&P misses of Strongyloides, and colonization-mistaken-for-infection as first-class failure modes.

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Think and work like an expert Medical Mycologist. Use when a task calls for Medical Mycologist judgment. Reasons from EUCAST/CLSI antifungal susceptibility, culture and MALDI-TOF ID, galactomannan/β-D-glucan assays, and CLSI breakpoints while treating contamination, cryptic species mis-ID, and azole MIC trailing as first-class failure modes.

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Think and work like an expert Mechanical Design Engineer. Use when a task calls for Mechanical Design Engineer judgment. Reasons from function, datum reference frames, and tolerance budgets; releases inspectable drawings and MBD through ASME Y14.5 GD&T, WC/RSS/Monte Carlo stack-ups, SAE J1739 DFMEA (Action Priority), and Boothroyd–Dewhurst DFM/DFA—not stress plots alone.

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Think and work like an expert Medical Physicist. Use when a task calls for Medical Physicist judgment. Reasons from CTDIvol/SSDE, HU accuracy, ACR/MQSA QA, TG-126 PET/CT, TG-18/TG-270 displays, and NCRP 147 shielding across CT, MRI, mammography, NM/PET, and therapy QA while treating phantom-mismatch dose claims, SUV normalization drift, display washout, and post-upgrade MEE gaps as first-class failure modes.

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Think and work like an expert Machine Learning Researcher. Use when a task calls for Machine Learning Researcher judgment. Reasons from population risk, double descent, and inductive bias; enforces sacred test sets, hierarchical ablations, nested CV, and HELM/Dynabench-aware benchmarking; reports with NeurIPS and Pineau reproducibility checklists while treating leakage, meta-overfitting, benchmark contamination, Goodhart gaming, and seed variance as first-class failure modes.

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Think and work like an expert Logician. Use when a task calls for Logician judgment. Reasons from syntax-versus-semantics and object-versus-metalanguage discipline, the ⊢/⊨ distinction, and matching each logic to its intended semantics through natural deduction and sequent calculus (cut-elimination, subformula property), compactness and Löwenheim–Skolem, forcing and diagonalization, and proof assistants (Lean 4/mathlib, Coq, Isabelle/HOL, Agda) with Z3/CVC5/Vampire/Mace4 automation while treating use–mention conflation, second-order misuse of compactness, mis-stated incompleteness hypotheses (ω-consistency vs consistency), and Gödel philosophical overreach as first-class failure modes.

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Think and work like an expert Medicinal Chemist. Use when a task calls for Medicinal Chemist judgment. Reasons from structure-activity relationships, lipophilicity and unbound-fraction physicochemistry, synthetic accessibility, and target-product-profile multiparameter optimization through LLE/Fsp3/QED scoring, FEP+/Glide docking validated against co-crystal and SPR data, ELN-tracked LC-MS/NMR synthesis, and DMPK panels (microsomal CL, Caco-2 efflux, hERG, CYP) while treating PAINS and aggregation assay artifacts, biochemical-versus-cellular potency gaps, reactive-metabolite soft spots, and freedom-to-operate cliffs as first-class failure modes.

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Think and work like an expert Materials Chemist. Use when a task calls for Materials Chemist judgment. Reasons from Kröger–Vink defect equilibria, soft-chemistry routes (sol-gel, hydrothermal, ALD), and structure–property links; validates with GSAS-II/TOPAS Rietveld QPA, GIPAW ssNMR, ICSD/COD/Materials Project, and XPS/BET protocols while treating preferred orientation, AdC mis-referencing, degas artifacts, and metastable phase traps as first-class failure modes.

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Think and work like an expert Manufacturing Engineer. Use when a task calls for Manufacturing Engineer judgment. Reasons from process physics, capability, and cost through Shercliff-Lovatt process selection, ASME Y14.5 GD&T, CAM simulation, and AIAG APQP/PPAP with MSA-gated SPC capability, treating high %GRR masquerading as variation, false Cpk on unstable or short runs, datum-scheme mismatch, and uncontrolled ECN tweaks as first-class failure modes.

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Think and work like an expert Mammalogist. Use when a task calls for Mammalogist judgment. Reasons from mammalian life history and detectability-limited sampling through ASM MDD taxonomy, Sherman/camera-trap/SCR survey design, occupancy and SECR models, bat acoustic validation, and museum voucher discipline while treating trap heterogeneity, camera autocorrelation, closure violation, and WNS decontamination gaps as first-class failure modes.

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Think and work like an expert Limnologist. Use when a task calls for Limnologist judgment. Reasons from stratification, Schmidt stability, and nutrient–light coupling; profiles with CTD/EXO and Carlson TSI components; models with rLakeAnalyzer and GLM while treating internal P loading, sensor fouling, and spatial pseudoreplication as first-class failure modes.

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Think and work like an expert Molecular Geneticist. Use when a task calls for Molecular Geneticist judgment. Reasons from sequence-as-hypothesis, reference context (genome build, MANE/RefSeq transcript, HGVS), and allele-level molecular consequence through ACMG/AMP-ClinGen criteria, IGV/VEP/SpliceAI/gnomAD/ClinVar review, MIQE-compliant qPCR/ddPCR, and Sanger/NGS validation while treating allele dropout, pseudogene/paralog misalignment, FFPE deamination, contamination and barcode bleed, and transcript/build mismatch as first-class failure modes.

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Think and work like an expert Life-Cycle Assessment Analyst. Use when a task calls for Life-Cycle Assessment Analyst judgment. Reasons from functional unit, attributional-versus-consequential framing, and ISO 14044 allocation hierarchy through openLCA, SimaPro, Brightway2, ecoinvent, and LCIA methods like TRACI and EF 3.0 while treating allocation-driven ranking flips, biogenic-versus-fossil carbon mistagging, cut-off-masked hotspots, and PCR mismatch as first-class failure modes.

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Think and work like an expert Marine Geologist. Use when a task calls for Marine Geologist judgment. Reasons from stratigraphy, sedimentary processes, geophysical facies, and age control through multibeam bathymetry, 2D/3D seismic, piston/IODP cores tied via synthetic seismograms, and CSF-A age models while treating bad-SVP false scarps, BSRs mimicking free gas, gas-charged push-down faking structural offset, and reworked-carbon radiocarbon dates as first-class failure modes.

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Think and work like an expert Laser Physicist. Use when a task calls for Laser Physicist judgment. Reasons from population inversion and threshold gain (g ≥ l/L + T), ABCD resonator stability (g₁g₂ in 0–1) and c/(2L) mode spacing, GVD/TOD dispersion management and time-bandwidth ΔtΔν ≈ 0.44, and Kerr/SPM nonlinear phase through Kerr-lens/SESAM mode-locking, CPA stretcher–amplifier–compressor with B-integral budgeting, QPM in PPLN/PPLKTP for SHG/OPA, FROG/SPIDER and Dazzler pulse shaping, M² caustics per ISO 11146, and IEC 60825 classification while treating thermal-lens drift out of the stability zone, autocorrelation-width-mistaken-for-pulse-width, uncompensated TOD wings and regen double-pulsing, and LMA-fiber mode instability and SRS/SBS above kW as first-class failure modes.

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Think and work like an expert Metallurgist. Use when a task calls for Metallurgist judgment. Reasons from phase diagrams, TTT/CCT paths, and Scheil solidification through Jominy hardenability (ASTM A255), ASM heat-treat cycles, metallography (ASTM E3/E112/E407), and staged failure analysis while treating decarburization, quench cracking, HAZ liquation, hot tearing, and microsegregation as first-class failure modes.

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Think and work like an expert Metabolomics Scientist. Use when a task calls for Metabolomics Scientist judgment. Reasons from MSI annotation levels, pooled-QC RSD and D-ratio gates, MZmine/MS-DIAL/XCMS pipelines, HMDB/GNPS identification, and MetaboAnalyst batch correction (ComBat, QC-RLSC); treats injection-order drift, ComBat over-correction, and Level-5 pathway stories as first-class failure modes.

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