271 skills · sorted by relevance
Estimate causal effects from observational and experimental data — DAGs, confounding control, quasi-experimental designs, and sensitivity analysis. Use when you need "what causes what," not just correlation.
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Pino logging, Sentry error tracking, Axiom - structured logging with correlation IDs, error boundaries, performance monitoring, alerting
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Pivots on indicators of compromise across multiple data sources by correlating a seed set of IOCs against logs to find co-occurring indicators, hosts, and timeframes that expand the investigation. Activates for requests to pivot on IOCs, correlate indicators across data sources, or expand an investigation from a seed indicator set.
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Analyze thermal-fluid engineering systems, experiments, CFD, and correlations with explicit assumptions, validity limits, uncertainty, and mechanism-based interpretation. Use for heat transfer, fluid mechanics, phase change, HVAC, energy systems, turbomachinery, piping, or thermal management.
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Apply source-aware mechanical-engineering judgment to research, analysis, coding, writing, teaching, research identity, and release work. Use for thermal-fluid systems, heat transfer, fluid mechanics, thermodynamics, HVAC, energy systems, turbomachinery, piping, multiphase flow, experiments, correlations, CFD, reduced-order models, AI/ML, uncertainty, engineering datasets, literature reviews, citations, manuscripts, reviewer revisions, Overleaf packages, figures, proposals, research software, reproducibility, public releases, engineering teaching materials, or a research-project logo and visual identity.
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Leverages BigQuery's built-in machine learning and GenAI capabilities for advanced data analytics. Use when you need to write SQL queries that perform time-series forecasting, predict values, detect outliers or anomalies, find key drivers, perform semantic search or vector search, classify text, calculate similarity, summarize content, translate language, evaluate models, filter by semantic conditions, measure the causal effect of an intervention, compute correlations between columns, detect change points or structural breaks, extract trend or seasonality components, or leverage generative AI capabilities in BigQuery. Do not use for general BigQuery dataset, table, or job management requests.
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Plan and execute integrative analysis combining multiple ENCODE experiments for cross-dataset or multi-omic workflows. Use when the user wants to combine experiments, perform cross-dataset comparison, multi-omic integration, peak overlap analysis, differential binding, signal correlation, chromatin state segmentation, enhancer-gene linkage, or any analysis that requires merging or comparing data from two or more ENCODE experiments. Covers same-assay cross-sample, multi-omic same-sample, cross-organism, and perturbation integration designs. Guides compatibility checks, batch effect detection, normalization, integration strategy selection, and provenance documentation.
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Analyzes SIEM alert pipelines for rule optimization, alert fatigue reduction, criticality scoring, asset-based prioritization, and correlation rule design using NIST CSF and detection engineering principles..
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Instrument applications with Azure Application Insights and OpenTelemetry for end-to-end observability. Use this skill when users ask about telemetry, tracing, metrics, logging, or monitoring setup. Covers SDK setup, correlation, sampling, dashboards, and alerts per OpenTelemetry standards.
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Applies game theory to multi-agent coordination protocols with advisory claims, repeated interactions, daemon-mediated correlation, and deviation penalties. Use for Nash equilibrium checks, folk-theorem cooperation analysis, correlated-equilibrium routing, and price-of-anarchy audits in strategic agent systems. NOT for consumer pricing, card-game strategy, or general microeconomics outside agent coordination.
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Summary statistics, data exploration, and descriptive analysis. Use for: summary stats, describe data, data exploration, distributions, means, medians, correlations, cross-tabs.
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Calculate statistical power and sample sizes for RCTs. Use when user mentions: power analysis, sample size calculation, minimum detectable effect, MDE, statistical power, effect size, clustering effects, design effect, ICC, intra-cluster correlation.
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Aligns sample metadata with count matrices and constructs design matrices for downstream DE, handling the alphabetical-reference-level trap (relevel BEFORE DESeq), LRT reduced-model rules, the interaction-term resultsNames trap, continuous-covariate scaling and splines, repeated measures via duplicateCorrelation or dream, high-cardinality categorical pseudo-singular designs, sample swap detection via XIST/RPS4Y1 expression and somalier/NGSCheckMate genotypes, SABV (sex-as-biological-variable) mandate, Simpson's-paradox collapsing of technical replicates, and the `~ 0 + group` parameterization for clean contrasts. Use when building a design matrix, troubleshooting reversed fold-change direction, encoding paired or repeated-measures designs, detecting sample swaps, deciding sex-as-covariate, or aggregating technical replicates.
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Aligns and QCs methylated-RNA-immunoprecipitation (MeRIP / m6A-seq) IP and input libraries using STAR or HISAT2 splice-aware mapping, samtools sort/index, IP/input matched-pair tracking, antibody-lot metadata recording, replicate concordance via deepTools multiBamSummary + plotCorrelation, IP enrichment QC via plotFingerprint and per-transcript IP/input ratio distributions, library-complexity saturation curves via PreSeq, and the explicit do-NOT-deduplicate convention for standard non-UMI MeRIP. Use when preparing paired IP and input BAM files for exomePeak2 / MeTPeak / MACS3 peak calling, evaluating MeRIP replicate concordance and IP enrichment, deciding whether to deduplicate (standard MeRIP typically NOT), choosing genome-vs-transcriptome alignment for downstream peak vs m6Anet workflows, recording antibody clone and lot metadata for cross-batch reconciliation, detecting failed IPs via saturation curves and IP/input distribution shape, or generating IP-over-Input bigWig tracks for visualisation.
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Build weighted gene co-expression networks to identify modules of co-regulated genes, relate them to phenotypes, and find hub genes using WGCNA, hdWGCNA, MEGENA, CEMiTool, and Gaussian graphical models. Covers signed-network choice, soft-threshold selection, module preservation, and the marginal-vs-partial-correlation distinction. Use when finding co-expression modules, identifying hub genes, relating gene networks to clinical or experimental traits, or building single-cell co-expression networks. For directed TF-target inference see scenic-regulons and grn-inference; for condition rewiring see differential-networks.
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Expert-level statistics knowledge. Use when working with probability distributions, hypothesis testing, regression, Bayesian statistics, statistical inference, experimental design, ANOVA, or statistical modeling. Also use when the user mentions 'p-value', 'confidence interval', 'hypothesis test', 'regression', 'ANOVA', 'chi-square', 't-test', 'Bayesian', 'maximum likelihood', 'statistical significance', 'correlation', 'normal distribution', or 'sampling distribution'.
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Use when defining or auditing the activation event — aha-moment selection, retention correlation, falsifiable definition. Triggers on 'what is our aha moment', 'redefine activation'.
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Runs an 11-step data cleaning and variable screening pipeline for pre-loan credit risk models: sample analysis, OOS split, missing-rate, IV, PSI, and correlation filters. Use when preparing raw credit data for scorecard or default-prediction modeling.
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Detects early-stage ransomware indicators in network traffic before encryption begins, including initial access broker activity, command-and-control beaconing, credential harvesting, reconnaissance scanning, and staging behavior. Uses network detection tools (Zeek, Suricata, Arkime), SIEM correlation rules, and threat intelligence feeds to identify ransomware precursor patterns such as Cobalt Strike beacons, Mimikatz network signatures, and RDP brute-force attempts. Activates for requests involving pre-ransomware detection, network-based ransomware indicators, or early warning ransomware monitoring.
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Detects and prevents code injection attacks targeting serverless functions (AWS Lambda, Azure Functions, Google Cloud Functions) through event source poisoning, malicious layer injection, runtime command execution, and IAM privilege escalation via function modification. The analyst combines static analysis of function code, CloudTrail event correlation, runtime behavior monitoring, and IAM policy auditing to identify injection vectors across the expanded serverless attack surface including API Gateway, S3, SQS, DynamoDB Streams, and CloudWatch event triggers. Activates for requests involving Lambda security assessment, serverless injection detection, function event poisoning analysis, or serverless privilege escalation investigation.
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Identifies lateral movement techniques in enterprise networks by analyzing authentication logs, network flows, SMB traffic, and RDP sessions using Zeek, Velociraptor, and SIEM correlation rules to detect attackers moving between systems.
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Detect lateral movement in Azure AD/Entra ID environments using Microsoft Graph API audit logs, Azure Sentinel KQL hunting queries, and sign-in anomaly correlation to identify privilege escalation, token theft, and cross-tenant pivoting.
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Detect LSASS credential dumping, SAM database extraction, and NTDS.dit theft using Sysmon Event ID 10, Windows Security logs, and SIEM correlation rules
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Detects command-and-control (C2) communications tunneled through DNS protocol including DNS tunneling tools (Iodine, dnscat2, dns2tcp, Cobalt Strike DNS beacon), domain generation algorithms (DGA), encoded payload delivery via TXT/CNAME records, and DNS beaconing patterns. Covers Shannon entropy analysis of query subdomains, statistical anomaly detection, ML-based DGA classification, passive DNS correlation, and Zeek/Suricata signature development. Activates for requests involving DNS-based C2 detection, DNS tunnel identification, suspicious DNS traffic investigation, or DGA domain classification.
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