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Automate Diffbot operations through Rube MCP, a connection for agent tools. The skill discovers available actions and their required inputs, checks the Diffbot connection, and runs selected tools using Composio's toolkit.
Automate Diffbot operations through Rube MCP, a connection for agent tools. The skill discovers available actions and their required inputs, checks the Diffbot connection, and runs selected tools using Composio's toolkit.
Add a diffusion model or Diffusers generation pipeline to SGLang. Examine reference code, choose a suitable pipeline structure, reuse existing components, and implement model settings and processing stages, with guidance for later multi-GPU support.
Build image generation workflows in Python with Stable Diffusion and HuggingFace Diffusers. The guide covers text prompts, transforming existing images, replacing selected regions, controlling composition, applying learned styles, and adjusting memory use during generation.
Build image generation workflows in Python with Stable Diffusion and HuggingFace Diffusers. The guide covers text prompts, transforming existing images, replacing selected regions, controlling composition, applying learned styles, and adjusting memory use during generation.
Quantize diffusion transformers with NVIDIA ModelOpt, using FP8 or NVFP4 lower-precision numbers, and prepare the saved weights for SGLang Diffusion. Follow a workflow for loading, checking output quality, and comparing speed under matching conditions.
Review a diffusers contribution before opening a pull request. Check the full change against project rules, trace potentially unused code, and receive a severity-based report separating required fixes from points to discuss with reviewers.
Compares Hi-C contact maps between conditions across the right scale -- differential bin-pair contacts (multiHiCcompare, diffHic), differential A/B compartments (dcHiC), differential TAD boundaries (delta insulation), and differential loops (diffloop, DiffHiChIP) -- with distance-stratified between-sample normalization, replicate-aware NB-GLM FDR, HiCRep SCC reproducibility gating, and CNV correction for cancer/aneuploid samples. Use when comparing Hi-C between treatment and control, finding differential contacts/compartments/boundaries/loops, normalizing two maps of unequal depth, choosing a replicate-aware test, gating replicates with SCC, or correcting copy-number artifacts before a tumor-vs-normal comparison.
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Compares Hi-C contact maps between conditions across the right scale -- differential bin-pair contacts (multiHiCcompare, diffHic), differential A/B compartments (dcHiC), differential TAD boundaries (delta insulation), and differential loops (diffloop, DiffHiChIP) -- with distance-stratified between-sample normalization, replicate-aware NB-GLM FDR, HiCRep SCC reproducibility gating, and CNV correction for cancer/aneuploid samples. Use when comparing Hi-C between treatment and control, finding differential contacts/compartments/boundaries/loops, normalizing two maps of unequal depth, choosing a replicate-aware test, gating replicates with SCC, or correcting copy-number artifacts before a tumor-vs-normal comparison.
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Identifies differential m6A methylation between conditions from MeRIP-seq paired IP/input data using exomePeak2 with `bam_ip` + `bam_input` (control arm) and `bam_treated_ip` + `bam_treated_input` (treatment arm) for integrated GC-bias-aware differential calling (Liu 2022 *NAR Genom Bioinform* 4:lqac046), QNB beta-binomial test (Liu 2017 *BMC Bioinformatics* 18:387), MeTDiff HMM-based differential bundled with MeTPeak, RADAR (Zhang 2019 *Genome Biol* 20:294) with its `filterBins -> diffIP -> reportResult` workflow, and the defensible paired-symmetric case of edgeR / DESeq2 on featureCounts-on-peaks matrices when batch / lot covariates need explicit fixed-effect handling (exomePeak2's top-level API does NOT accept arbitrary covariates). Covers paired vs unpaired vs interaction designs, batch confounding (antibody lot, RNA prep, sequencing run) and the per-lot meta-analysis strategy when exomePeak2 is the primary caller, the stoichiometry-vs-expression-vs-IP-efficiency confound that all MeRIP differential methods inherit, normalisation choice (size factor on IP, on input, on per-sample IP/input ratio), the McIntyre 2020 reproducibility caveat, effect-size filtering as a guardrail against under-powered N=2 designs, and orthogonal-validation routes for absolute stoichiometry (GLORI / SAC-seq / m6Anet `mod_ratio`). Use when comparing m6A levels across two or more conditions, choosing between exomePeak2 / QNB / RADAR / MeTDiff for a given design, handling batch confounding when exomePeak2's API is too rigid, normalising against input properly, distinguishing real hyper- / hypo-methylation from expression-level shifts, applying effect-size thresholds, interpreting volcano plots of differential peaks, or planning a follow-up orthogonal stoichiometry validation.
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Compares Hi-C contact maps between conditions across the right scale -- differential bin-pair contacts (multiHiCcompare, diffHic), differential A/B compartments (dcHiC), differential TAD boundaries (delta insulation), and differential loops (diffloop, DiffHiChIP) -- with distance-stratified between-sample normalization, replicate-aware NB-GLM FDR, HiCRep SCC reproducibility gating, and CNV correction for cancer/aneuploid samples. Use when comparing Hi-C between treatment and control, finding differential contacts/compartments/boundaries/loops, normalizing two maps of unequal depth, choosing a replicate-aware test, gating replicates with SCC, or correcting copy-number artifacts before a tumor-vs-normal comparison.
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Identifies differential m6A methylation between conditions from MeRIP-seq paired IP/input data using exomePeak2 with `bam_ip` + `bam_input` (control arm) and `bam_treated_ip` + `bam_treated_input` (treatment arm) for integrated GC-bias-aware differential calling (Liu 2022 *NAR Genom Bioinform* 4:lqac046), QNB beta-binomial test (Liu 2017 *BMC Bioinformatics* 18:387), MeTDiff HMM-based differential bundled with MeTPeak, RADAR (Zhang 2019 *Genome Biol* 20:294) with its `filterBins -> diffIP -> reportResult` workflow, and the defensible paired-symmetric case of edgeR / DESeq2 on featureCounts-on-peaks matrices when batch / lot covariates need explicit fixed-effect handling (exomePeak2's top-level API does NOT accept arbitrary covariates). Covers paired vs unpaired vs interaction designs, batch confounding (antibody lot, RNA prep, sequencing run) and the per-lot meta-analysis strategy when exomePeak2 is the primary caller, the stoichiometry-vs-expression-vs-IP-efficiency confound that all MeRIP differential methods inherit, normalisation choice (size factor on IP, on input, on per-sample IP/input ratio), the McIntyre 2020 reproducibility caveat, effect-size filtering as a guardrail against under-powered N=2 designs, and orthogonal-validation routes for absolute stoichiometry (GLORI / SAC-seq / m6Anet `mod_ratio`). Use when comparing m6A levels across two or more conditions, choosing between exomePeak2 / QNB / RADAR / MeTDiff for a given design, handling batch confounding when exomePeak2's API is too rigid, normalising against input properly, distinguishing real hyper- / hypo-methylation from expression-level shifts, applying effect-size thresholds, interpreting volcano plots of differential peaks, or planning a follow-up orthogonal stoichiometry validation.
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Compare software binaries before and after a security patch to identify the underlying flaw. Guide creation of a proof of concept, a small vulnerability demonstration, and compare its behavior across patched and unpatched versions.
Generate commit messages from git diffs, staged changes, or written descriptions. Explain the reason and problem behind each change using Conventional Commits, a structured message format, and suggest separate messages for unrelated changes.
Integrate a model or pipeline into diffusers, from file structure and weight conversion to tests and documentation. Verify numerical agreement with the original implementation, with modular pipelines as the preferred starting point for new integrations.
Run diffusers generation pipelines from a terminal and save their outputs. Inspect accepted inputs without downloading model weights, apply LoRA adapters during generation, run remotely through HF Jobs, and inspect software and GPU environment details.
Locate BotProfile::Difficulty in CS2 server.dll / libserver.so via IDA Pro MCP and emit a fresh, minimal-unique signature or offset for the local gamedata entry "BotProfile::Difficulty" (symbol BotProfile_Difficulty). This is a VIRTUAL function - resolve the BotProfile::Difficulty vtable via RTTI and identify the slot, then emit the slot. Verify by xrefs from expected call sites. vtable slots commonly differ between platforms - never assume identical indices. Trigger: BotProfile_Difficulty, BotProfile::Difficulty
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Generate candidate positions and orientations for small molecules binding to proteins with DiffDock and DiffDock-L. Prepare single or batch docking runs, organize predicted poses by model confidence, and review validation needs without treating confidence as binding affinity.
Choose SGLang Diffusion settings for a specific model, GPU, and memory budget. Compare generation speed, memory use, and output quality to select command-line options, including CPU offloading, multiple GPUs, caching, and reduced precision.
Package an existing custom diffusers block into a directory ready for Hub upload. Select a class from a Python file and save its source, configuration, and associated files so others can load the block.
Review local code changes with git diff and update the matching pages under docs/. Keep commands, settings, examples, and navigation aligned with current behavior so readers can understand the changes without reading the code.
Compare gene co-expression and regulatory networks between biological conditions to find rewired relationships using DiffCorr, DiffCoEx, DINGO/iDINGO, and CoDiNA. Covers the differential-connectivity-is-not-differential-expression distinction, the pairwise multiple-testing explosion, marginal vs partial (direct) rewiring, and the underpowered-rewiring failure mode. Use when comparing co-expression networks between disease vs control, treatment, or developmental stages, or finding hub genes that rewire without changing mean expression. For single-condition modules see coexpression-networks; for differential expression of means see differential-expression/de-results.
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AIGC 创作工作流 (AIGC 创作工作流 / AIGC Creative Workflow — 以「生成式 AI 视觉创作（图像 + 视频）的工程化创作流水线」为对象的认知操作系统：从「需求/概念（要做什么画面/镜头/风格）→ 模型与工具选型（Midjourney / Stable Diffusion·SDXL·Flux / ComfyUI / 可灵 Kling / 即梦 Jimeng / Runway / Vidu / Sora）→ Prompt 与参数设计（提示词工程、风格描述、负向、种子、CFG/步数/采样器、参考图）→ 可控生成（ControlNet / LoRA / IPAdapter / inpainting / 图生图 / 局部重绘 / 区域控制）→ 批量出图与筛选 → 精修与合成（放大/超分、修手修脸、PS/AE 后期、抠图合成）→ 图生视频/文生视频（首尾帧、运镜、时长、一致性、对口型）→ 商业交付与迭代复现（参数留存、工作流文件复用、版权与可商用判断）」的完整创作-工程-交付决策链。覆盖 (a) 第一性张力 — **可控性/工程化复现（ControlNet/LoRA/ComfyUI 节点工作流/固定种子与参数/可复现可迭代）⇄ 随机性/抽卡玄学（出图随机、prompt 玄学、抽卡刷图、靠运气）**；**审美/创意/艺术指导主导（人的审美判断、概念设计、构图、镜头语言、艺术总监能力——'模型是地板，审美是天花板'）⇄ 工具/模型/参数主导（堆模型能力、堆参数、堆 LoRA、以为换个大模型就行）**；**开源生态/本地可控（Stable Diffusion / ComfyUI / Flux / civitai / liblib 本地部署可定制可控可商用、显卡门槛）⇄ 闭源商业/易用黑盒（Midjourney / 可灵 / 即梦 / Runway 开箱即用但不可精控、按量付费、黑盒）**；**图像生成（T2I/I2I：Midjourney / SDXL / Flux）⇄ 视频生成（T2V/I2V：可灵 / Runway Gen-3 / Vidu / 即梦 / Sora，2024-2025 前沿从图迁移到视频）**；**生产力/商业量产（替代或增强传统设计/插画/电商/广告/影视分镜流程、降本提效、批量）⇄ 纯艺术创作/作者表达（个人风格、实验性、作品集）**；**效率/批量（一次出几十张筛选、商单走量、自动化 pipeline）⇄ 质量/精控（单张精修、商业可用级细节、修手修脸修穿帮）**。(b) 核心工作流 / pipeline（最标准、最易蒸高质量 + CLI 化）— 单图创作链：概念/参考收集（moodboard/风格定位/竞品）→ 模型工具选型（按可控性/风格/成本/可商用判断 MJ vs SD/Flux vs 国产）→ Prompt 与参数设计（主体/风格/光影/镜头/负向词/CFG/采样器/分辨率/种子）→ 首轮出图与方向筛选 → 可控迭代（ControlNet 控构图/姿态/线稿、LoRA 控风格/角色一致性、图生图重绘、inpainting 局部修）→ 放大超分与精修（高清放大/修手修脸/后期调色合成）→ 交付与参数留存（工作流文件/种子/参数复现）。视频创作链：分镜/脚本→首帧出图（图像链产出关键帧）→图生视频（运镜/时长/首尾帧/动态强度）→多镜头一致性（角色/场景/风格统一）→对口型/配音/配乐→剪辑合成→交付。ComfyUI 工程链：节点工作流搭建（加载器/采样/ControlNet/放大/面部修复节点）→ 参数化与复用→批量队列→工作流分享（civitai/openart workflow json）。(c) 工具栈 — 闭源图像（Midjourney v6/v7、DALL·E 3、Adobe Firefly、Ideogram、Recraft）、开源图像与底座（Stable Diffusion 1.5/SDXL/SD3、Flux.1 dev/schnell（Black Forest Labs）、ComfyUI（节点式）、Automatic1111/Forge WebUI、Fooocus）、可控生成插件（ControlNet、LoRA、IPAdapter、AnimateDiff、inpainting/outpainting、ReActor 换脸、面部修复 CodeFormer/GFPGAN、放大 ESRGAN/SUPIR/Topaz）、模型/资源社区（Hugging Face、Civitai、liblib 哩布、吐司 Tusi、openart）、视频生成（可灵 Kling、即梦 Dreamina/Jimeng、Runway Gen-3/Gen-4、Luma Dream Machine、Pika、Vidu、海螺 Hailuo、Sora、Wan 通义万相、MiniMax）、辅助（Magnific 放大、Krea、Photoshop/After Effects 后期、ChatGPT/Claude 写 prompt、reverse prompt 反推）。(d) 知识正典 — AIGC 创作 canon 横跨论文/工程/社区教程：奠基论文（DDPM、Latent Diffusion/Stable Diffusion（Rombach et al）、DiT、ControlNet（Zhang et al）、LoRA、DreamBooth、Textual Inversion、SDEdit、IP-Adapter、视频扩散 SVD/Sora 技术报告）、官方文档与模型卡（Stability AI、Black Forest Labs Flux、ComfyUI 文档、Midjourney docs、可灵/即梦官方教程、Hugging Face diffusers）、社区教程与工作流（ComfyUI 官方示例、civitai 文章、B站/YouTube 创作者长教程、openart workflow）、prompt 工程资源（Midjourney 风格库、提示词指南）。(e) figures/流派 — 模型/工具创造者（Midjourney David Holz、Stability AI Emad/Robin Rombach、Black Forest Labs（Flux，原 SD 团队）、ComfyUI comfyanonymous、ControlNet 张吕敏 Lvmin Zhang、AUTOMATIC1111、可灵/即梦/快手字节团队）、创作者 KOL 与教育者（Midjourney/SD 头部创作者、ComfyUI 工作流大神、AI 视频创作者、国内 B站/抖音 AIGC 教程作者、独立 AI 艺术家）、行业分析与评测（AI 工具评测、生成式 AI 创作生态观察者）。流派分歧：开源可控派（SD/ComfyUI/Flux 本地精控）vs 闭源易用派（MJ/可灵开箱即用）、工程化派（节点工作流/可复现/参数化）vs 玄学抽卡派（prompt 玄学/堆词/抽卡）、审美主导派（'模型是地板审美是天花板'）vs 工具主导派（堆模型堆参数）、图像派 vs 视频派、艺术创作派 vs 商业生产力派、国产工具派（可灵/即梦/liblib）vs 海外工具派（MJ/Flux/Runway）。(f) 行业话术/黑话 — 出图 / 抽卡 / 刷图 / 炼丹（训练 LoRA）/ 喂图 / 垫图（参考图/图生图）/ 控图 / 锁种子 seed / CFG / 采样器 sampler / 步数 steps / 重绘幅度 denoise / 提示词 prompt / 咒语 / 负向 negative / 权重 / tag / 大模型 checkpoint / 底模 / LoRA / ControlNet / 控线稿/openpose/depth / IPAdapter / inpainting 局部重绘 / outpainting 扩图 / 高清放大 / 超分 / 修手 / 崩手 / AI 味 / 风格 / 角色一致性 / 工作流 workflow / 节点 / 跑图 / 队列 / 文生图 T2I / 图生图 I2I / 文生视频 T2V / 图生视频 I2V / 首帧/尾帧 / 运镜 / 动态强度 / 时长 / 对口型 / 一致性 / 可商用 / 训练集 / 过拟合 / 翻车 / 穿帮。(g) 争议/批判 — 「版权与训练数据」（模型训练用未授权作品、生成图版权归属、可商用风险、洗图/伪原创）、「AI 替代创作者就业」（替代画师/插画师/设计师/摄影、行业冲击与转型）、「AI 味与审美趋同」（生成图同质化、套模板、缺乏原创审美）、「玄学 prompt 神话与割韭菜」（'咒语'神秘化、'7天 AIGC 变现/月入过万'付费课割韭菜、抽卡当能力）、「工具快速迭代与淘汰焦虑」（模型月月换、工作流频繁失效、追新疲劳）、「开源 vs 闭源之争」（可控可商用 vs 易用黑盒）、「质量天花板」（修手修脸穿帮、长视频一致性、可控性仍有限）。(h) 大量隐性创作手艺 + 审美 + 工程 + 沟通软技能（prompt 的描述功底与审美词汇、参数与采样的手感、ControlNet/LoRA 的组合控制经验、节点工作流的搭建与调试、批量筛选的审美眼力、修图合成的后期功底、镜头语言与运镜设计、角色/风格一致性的控制、商业需求的翻译与交付、版权与可商用的判断）是高 tacit、靠大量实操跑图 + 审美积累 + 工程调试经验的核心。水分极高（大量'咒语速成/一键变现/AI 绘画割韭菜'营销
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Analyze the dynamics of diffusion processes using stochastic differential equations, Fokker-Planck equations, first-passage time distributions, and parameter sensitivity analysis. Use when deriving probability density evolution for a continuous-time diffusion process, computing mean first-passage times for bounded diffusion, analyzing how drift and diffusion parameters affect process behavior, or validating closed-form solutions against stochastic simulation.
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