36 skills · sorted by relevance
Build or review Vue.js 3 and Nuxt interfaces using practical patterns for components, shared state, navigation, and tests. Learn how to organize code and manage reactivity, the mechanism that updates the interface when data changes.
Address unwanted dog behaviors through desensitization, counter-conditioning, and management. Covers reactivity (to dogs, people, sounds), separation anxiety, resource guarding, excessive barking, and leash pulling using force-free methods with systematic threshold management. Use when a dog shows reactivity toward other dogs, people, or stimuli; when separation anxiety causes destructive behavior or vocalization; when resource guarding is present; or when behaviors like excessive barking or leash pulling interfere with daily life — after basic obedience is established.
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Use this skill for internal Vue reactivity and state-model work in the nuxt-ui-tools repository. Covers lean reactivity, query-state integration, when to use computed vs watch vs shallowRef, VueUse usage, and how to simplify over-layered state models.
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Designs covalent inhibitors and warheads targeting cysteine, lysine, serine, threonine, tyrosine, and aspartate residues, with explicit handling of warhead reactivity (acrylamide, chloroacetamide, vinyl sulfone, sulfonyl fluoride, fluorosulfate, aldehyde, boronate, nitrile), reversibility (kinact/Ki, t_residence), glutathione (GSH) stability, intrinsic reactivity assays, and covalent docking (DOCKovalent, GOLD, HCovDock). Use when designing covalent inhibitors for targeted covalent inhibition (TCI), KRAS G12C-style approaches, or rationalizing covalent SAR.
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Designs covalent inhibitors and warheads targeting cysteine (most common, 98% of covalent drugs), lysine, serine, threonine, tyrosine, and aspartate residues, with explicit handling of warhead reactivity (acrylamide, chloroacetamide, vinyl sulfone, sulfonyl fluoride, fluorosulfate, aldehyde, boronate, nitrile), reversibility (kinact/Ki, t_residence), glutathione (GSH) stability, intrinsic reactivity assays, and covalent docking (DOCKovalent, GOLD, HCovDock). Use when designing covalent inhibitors for targeted covalent inhibition (TCI), KRAS G12C-style approaches, or rationalizing covalent SAR.
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Designs covalent inhibitors and warheads targeting cysteine, lysine, serine, threonine, tyrosine, and aspartate residues, with explicit handling of warhead reactivity (acrylamide, chloroacetamide, vinyl sulfone, sulfonyl fluoride, fluorosulfate, aldehyde, boronate, nitrile), reversibility (kinact/Ki, t_residence), glutathione (GSH) stability, intrinsic reactivity assays, and covalent docking (DOCKovalent, GOLD, HCovDock). Use when designing covalent inhibitors for targeted covalent inhibition (TCI), KRAS G12C-style approaches, or rationalizing covalent SAR.
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Designs covalent inhibitors and warheads targeting cysteine (most common, 98% of covalent drugs), lysine, serine, threonine, tyrosine, and aspartate residues, with explicit handling of warhead reactivity (acrylamide, chloroacetamide, vinyl sulfone, sulfonyl fluoride, fluorosulfate, aldehyde, boronate, nitrile), reversibility (kinact/Ki, t_residence), glutathione (GSH) stability, intrinsic reactivity assays, and covalent docking (DOCKovalent, GOLD, HCovDock). Use when designing covalent inhibitors for targeted covalent inhibition (TCI), KRAS G12C-style approaches, or rationalizing covalent SAR.
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Designs covalent inhibitors and warheads targeting cysteine (most common, 98% of covalent drugs), lysine, serine, threonine, tyrosine, and aspartate residues, with explicit handling of warhead reactivity (acrylamide, chloroacetamide, vinyl sulfone, sulfonyl fluoride, fluorosulfate, aldehyde, boronate, nitrile), reversibility (kinact/Ki, t_residence), glutathione (GSH) stability, intrinsic reactivity assays, and covalent docking (DOCKovalent, GOLD, HCovDock). Use when designing covalent inhibitors for targeted covalent inhibition (TCI), KRAS G12C-style approaches, or rationalizing covalent SAR.
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Designs covalent inhibitors and warheads targeting cysteine (most common, 98% of covalent drugs), lysine, serine, threonine, tyrosine, and aspartate residues, with explicit handling of warhead reactivity (acrylamide, chloroacetamide, vinyl sulfone, sulfonyl fluoride, fluorosulfate, aldehyde, boronate, nitrile), reversibility (kinact/Ki, t_residence), glutathione (GSH) stability, intrinsic reactivity assays, and covalent docking (DOCKovalent, GOLD, HCovDock). Use when designing covalent inhibitors for targeted covalent inhibition (TCI), KRAS G12C-style approaches, or rationalizing covalent SAR.
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Create Angular components and services with guidance on state management, forms, and navigation. Adapt implementation choices to the project's Angular version, and check the resulting code through tests and builds.
Turn json-render specifications into SolidJS interfaces. This skill guides component registration, connects inputs to application state, handles actions and validation, and helps troubleshoot how changing values update the screen, including streamed UI generation.
Build Vue 3 components with TypeScript and Composition API, a way to organize component logic. Define inputs, events, and two-way bindings, manage reactive data, and use built-in components for transitions and state preservation.
Pinia stores, state management patterns, store setup, and reactivity with stores.
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Think and work like an expert Cell Biologist. Use when a task calls for Cell Biologist judgment. Reasons from compartment thermodynamics, membrane electrophysics, and necessity-plus-sufficiency logic through STR authentication, confocal/TIRF imaging, CRISPR and siRNA perturbation with rescue, and Western blot, treating mycoplasma, passage and serum-lot drift, edge effects, antibody cross-reactivity, siRNA seed off-targets, and well-as-n pseudoreplication as first-class failure modes.
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Think and work like an expert Atmospheric Chemist. Use when a task calls for Atmospheric Chemist judgment. Reasons from coupled photochemical OH-NOx-VOC radical budgets, heterogeneous aerosol uptake, and NOx-limited versus VOC-limited regimes through MCM/F0AM and GEOS-Chem/CMAQ/WRF-Chem models, OH-reactivity closure, PMF on AMS factors, HYSPLIT trajectories, and EKMA isopleths while treating chamber wall losses, instrument cross-sensitivities and inlet artifacts, and emission-inventory error as first-class failure modes.
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Symfony UX LiveComponent for reactive server-rendered UI -- components that re-render via AJAX on user interaction, zero JavaScript required. Use when building live search, real-time filtering, dynamic forms, inline validation, dependent selects, auto-save, polling, deferred/lazy rendering, or any UI that updates itself based on user input. Code triggers: AsLiveComponent, LiveProp, LiveAction, data-model, data-loading, data-live-action-url, ComponentWithFormTrait, LiveListener, emit, defer, lazy, polling. Also trigger when the user asks "how to build a search that filters as I type", "how to validate a form in real-time", "how to make a reactive component in PHP", "how to build dependent selects", "how to defer component rendering", "how to communicate between components via emit", "how to bind a form to a LiveComponent". Do NOT trigger for static reusable UI without reactivity (use twig-component), pure client-side JS behavior (use stimulus), or page-level navigation (use turbo).
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Stimulus JS framework for Symfony UX -- client-side behavior via HTML data attributes, zero server round-trips. Use when creating controllers for DOM manipulation, handling click/input/submit events, managing targets and values, wiring outlets between controllers, wrapping third-party JS libraries, or building toggles, dropdowns, modals, tabs, clipboard interactions. Code triggers: data-controller, data-action, data-target, data-*-value, data-*-class, data-*-outlet, stimulusFetch lazy, connect(), disconnect(), static targets, static values. Also trigger when the user asks "how do I add a click handler", "how to toggle a class", "how to build a dropdown/modal/tabs", "how to wrap a JS library in Symfony", "add keyboard shortcuts", "lazy-load a controller", "listen to global events", "communicate between controllers". Do NOT trigger for partial page updates without JS (use turbo), server-rendered reactivity (use live-component), or reusable Twig templates (use twig-component).
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Angular is Google's TypeScript-based frontend framework for building scalable single-page applications. It provides components, dependency injection, RxJS-based reactivity, routing, forms, HTTP client, and a powerful CLI for development.
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Angular is opinionated and comprehensive - it gives you everything: routing, forms, HTTP, dependency injection, testing. The learning curve is steep, but once you're in, you move fast. The structure it enforces is why enterprises love it. This skill covers Angular 17+, standalone components, signals, the new control flow syntax, and modern Angular patterns. Key insight: Angular's power is in its DI system and RxJS integration. Master those, and everything else follows. 2025 lesson: Standalone components are the future. NgModules aren't going away, but new projects should start standalone. Signals are Angular's answer to fine-grained reactivity - learn them. Use when "angular, angular component, angular service, angular routing, angular forms, rxjs, ngrx, angular signals, standalone component, angular ssr, angular, typescript, frontend, spa, enterprise, rxjs, signals, standalone" mentioned.
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Generates Angular code and provides architectural guidance. Trigger when creating projects, components, services, or HTTP communication, or for best practices on reactivity (signals, linkedSignal, resource, httpResource), queries and content projection, forms, dependency injection, routing, server and hybrid rendering (SSR, prerendering, hydration), accessibility (ARIA), animations, styling (component styles, Tailwind CSS), testing, naming conventions, or CLI tooling.
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Expert guide for SolidJS 2 and SolidStart — fine-grained reactivity, signals, createResource, and server-first rendering / Panduan ahli SolidJS 2 dan SolidStart — reaktivitas fine-grained, signals, createResource, dan rendering server-first.
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Expert guide for Svelte 5 (Runes) and SvelteKit 2+ — fine-grained reactivity, server-first architecture, form actions, and SSR/SSG / Panduan ahli Svelte 5 (Runes) dan SvelteKit 2+ — reaktivitas fine-grained, arsitektur server-first, form actions, dan SSR/SSG.
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Odoo OWL frontend engineering guidance covering components, templates, reactivity, hooks, props, plugins, registries, debugging, assets, and OWL 1/2/3 migration. Use when working with Odoo frontend components, @odoo/owl, static/src JavaScript/XML templates, signals, proxy, props, t-on, t-ref, t-model, registries, plugins, or OWL migrations.
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SolidJS expert including reactivity, components, and store patterns
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