34 skills · sorted by relevance
Helps build and review NeuroKit2 research workflows for physiological recordings such as ECG, respiration, and skin conductance. Covers preprocessing, time alignment, event analysis, heart rate variability, and complexity measures, while recording methods and checking data quality.
"Analyze and mitigate the bullwhip effect where demand variability amplifies upstream in supply chains. Use this skill when the user needs to diagnose order variability amplification, quantify the bullwhip ratio, or implement dampening strategies — even if they say 'why are our orders so volatile', 'supply chain variability', or 'demand amplification problem'.".
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Assess stock, index, or currency options by comparing expected price variability implied by option prices with actual historical variability. Summarize pricing, risk sensitivities, and patterns across expiry dates and exercise prices to inform strategy choices.
Generate a scaffolded sequence of practice problems with graduated difficulty and strategic variability. Use when creating worksheets, homework sets, or independent practice materials.
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Predicts access barriers in a learning task before delivery, given a learner variability profile. Distinguishes between barriers addressable through design and those requiring specialist support.
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Predicts access barriers in a learning task before delivery, given a learner variability profile. Distinguishes between barriers addressable through design and those requiring specialist support.
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Generate a scaffolded sequence of practice problems with graduated difficulty and strategic variability. Use when creating worksheets, homework sets, or independent practice materials.
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Climate physics, forcing, feedback, and attribution. Covers the greenhouse effect and radiative forcing, climate sensitivity, fast and slow feedbacks, the paleoclimate record, detection and attribution science, regional climate impacts, and the distinction between weather, climate variability, and forced climate change. Use when reasoning about global warming mechanisms, interpreting temperature or CO2 records, evaluating attribution claims for extreme events, or distinguishing signal from natural variability.
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Heart rate variability biometrics and emotional awareness training. Expert in HRV analysis, interoception training, biofeedback, and emotional intelligence. Activate on 'HRV', 'heart rate variability', 'alexithymia', 'biofeedback', 'vagal tone', 'interoception', 'RMSSD', 'autonomic nervous system'. NOT for general fitness tracking without HRV focus, simple heart rate monitoring, or diagnosing medical conditions (only licensed professionals diagnose).
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Recommends continuous subcutaneous insulin infusion (CSII) over multiple daily injections (MDI) for adults with type 1 diabetes who have achieved their A1C goal but experience severe hypoglycemia or high glucose variability, provided the patient and caregivers are willing and able to use the device. Consider CSII when clinicians hear 'A1C is at goal but patient has severe lows or glucose swings' or think 'pump for hypoglycemia-prone controlled T1DM'.
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Measure code performance and run benchmarks to investigate slow operations, regressions, or memory pressure. Establish a baseline, compare results under matching conditions, report variability, and rerun correctness tests after optimization.
Comprehensive biosignal processing toolkit for analyzing physiological data including ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use this skill when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements. Applicable for heart rate variability analysis, event-related potentials, complexity measures, autonomic nervous system assessment, psychophysiology research, and multi-modal physiological signal integration.
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Analyze transcription factor motif accessibility variability using chromVAR. Use when identifying which TF motifs show variable accessibility across samples or conditions in ATAC-seq data.
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Use when targeting Journal of Climate or deciding whether a climate-dynamics or climate-variability manuscript fits this venue. Encodes the journal's fit, the large-scale-climate-science bar, model-evaluation and statistical-rigor expectations, AMS house style, official-submission re-check, and desk-reject heuristics.
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Interactive cell annotation and image QC for IMC/MIBI using napari, napari-imc, Mantis Viewer, and cytomapper, covering the pixels-to-cell-table bridge, overlaying masks to catch segmentation/spillover artifacts, inter-annotator variability as the accuracy ceiling, contrast-as-threshold, and building class-balanced ground-truth label sets. Use when manually labeling cells, generating training data for a classifier, QC-ing segmentation on the image, confirming clusters are spatially real, or choosing an annotation viewer.
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Analyze TF motif accessibility variability across samples or single cells using chromVAR. Use when identifying TF motifs whose accessibility correlates with conditions, computing per-sample motif z-scores after matched background correction, comparing to ArchR / Signac equivalents, or distinguishing motif-accessibility signal from per-site footprinting.
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Dirichlet-multinomial mixture models can be used to describe variability in microbial metagenomic data. This package is an interface to code originally made available by Holmes, Harris, and Quince, 2012, PLoS ONE 7(2): 1-15, as discussed fu
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Comprehensive biosignal processing toolkit for analyzing physiological data including ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use this skill when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements. Applicable for heart rate variability analysis, event-related potentials, complexity measures, autonomic nervous system assessment, psychophysiology research, and multi-modal physiological signal integration.
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Apply the bioengineering, translational systems biology, and tissue modeling frameworks of Linda Griffith, Professor of Biological Engineering at MIT and tissue engineering pioneer. Use this skill whenever facing decisions, designs, or evaluations in bioengineering, tissue modeling, microphysiological systems (organs-on-chips), synthetic matrix design, disease subtyping, or drug target validation. Reach for this skill when evaluating preclinical models (human vs. animal), reframing overlooked or neglected pathologies into rigorous engineering challenges, selecting biomaterials, designing cell signal processing assays, or diagnosing operational flaws in experimental platforms (e.g., PDMS compound absorption or Matrigel lot variability).
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Think and work like an expert Geotechnical Scientist. Use when a task calls for Geotechnical Scientist judgment. Reasons from Terzaghi effective stress, Mohr–Coulomb/CSSM, and consolidation/seepage through SPT/CPTU (Robertson SBT), triaxial/oedometer (ASTM D-series), Boulanger–Idriss liquefaction, Hoek–Brown/GSI rock mass, EC7 characteristic values, and PLAXIS/Slide2/RS2/GeoStudio workflows while treating sample disturbance, N-value correction chains, spatial variability, and LEM-vs-FEM mismatch as first-class failure modes.
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Think and work like an expert Atmospheric Scientist. Use when a task calls for Atmospheric Scientist judgment. Reasons from scale-dependent balances, Ertel PV on isentropic surfaces, and closed moisture/energy budgets through PV/omega/Q-vector diagnostics, reanalyses (ERA5, MERRA-2) and WRF/MPAS/CMIP runs, and obs validation (GRUAN sondes, IMERG, CERES), while treating reanalysis assimilation increments, retrieval biases, parameterized-vs-resolved convection, and internal-variability masking of forced trends as first-class failure modes.
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Perform flux balance analysis (FBA) and flux variability analysis (FVA) on genome-scale metabolic models using COBRApy. Predict growth rates, metabolic fluxes, and optimal resource utilization. Use when predicting metabolic phenotypes or optimizing flux distributions.
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Operations management and lean production techniques for turning inputs into outputs under variability. Covers the Toyota Production System, seven wastes, just-in-time, kanban, jidoka, single-minute die exchange, 5 Whys, value stream mapping, bottleneck theory, and the distinction between mass production and flexible production. Use when diagnosing operational waste, designing production flows, setting up quality systems, or comparing batch-and-queue to one-piece flow.
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Use when a task needs the judgment of a Cutting/Slicing Machine Operator — calculating a portion weight overweight margin from measured weight variability to minimize giveaway while staying compliant, verifying a thickness setting against a new product lot's actual density rather than reusing a prior lot's setting, diagnosing declining cut quality as a blade-condition issue rather than compensating with thickness/speed, or adapting cut pattern to irregular input to improve yield.
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