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reactome-skill

Retrieve concise summaries from Reactome about biological pathways, events, participating molecules, and diagram-related data. Look up specific identifiers, search for relevant entries, or find pathways associated with an entity, and save the full response when needed.

OriginalShow the original description

Submit compact Reactome ContentService requests for pathway, event, participant, search, and diagram-related data. Use when a user wants concise Reactome summaries

See how to install

Good for

  • Looking up a pathway or event by ID
  • Finding pathways associated with a molecule
  • Checking participants in a biological event
  • Saving a full response for later review

Files included (3)

  • SKILL.md2.3 KB
  • agents/openai.yaml94 B
  • scripts/rest_request.py10.5 KB

SKILL.md (original)

Review the instructions the agent will receive before you install.

Operating rules

  • Use scripts/rest_request.py for all Reactome ContentService calls.
  • Use base_url=https://reactome.org/ContentService.
  • Single pathway or event lookups usually do not need max_items; list-style pathway membership calls are better with max_items=10.
  • Send Accept: application/json in headers when requesting JSON.
  • Re-run requests in long conversations instead of relying on older tool output.
  • Treat displayed ... in tool previews as UI truncation, not literal request content.

Execution behavior

  • Return concise markdown summaries from the script JSON by default.
  • Prefer these paths: data/query/<eventId>, data/pathways/low/entity/<identifier>, data/participants/<eventId>, and search endpoints.
  • If the user needs the full payload, set save_raw=true and report the saved file path.

Input

  • Read one JSON object from stdin.
  • Required fields: base_url, path
  • Optional fields: method, params, headers, json_body, form_body, record_path, response_format, max_items, max_depth, timeout_sec, save_raw, raw_output_path
  • Common Reactome patterns:
    • {"base_url":"https://reactome.org/ContentService","path":"data/query/R-HSA-199420","headers":{"Accept":"application/json"}}
    • {"base_url":"https://reactome.org/ContentService","path":"data/pathways/low/entity/P38398","params":{"species":"Homo sapiens"},"headers":{"Accept":"application/json"},"max_items":10}
    • {"base_url":"https://reactome.org/ContentService","path":"data/participants/R-HSA-199420","headers":{"Accept":"application/json"},"max_items":10}

Output

  • Success returns ok, source, path, method, status_code, warnings, and either compact records or a compact summary.
  • Use raw_output_path when save_raw=true.
  • Failure returns ok=false with error.code and error.message.

Execution

echo '{"base_url":"https://reactome.org/ContentService","path":"data/query/R-HSA-199420","headers":{"Accept":"application/json"}}' | python scripts/rest_request.py

References

  • No additional runtime references are required; keep the import package limited to this file and scripts/rest_request.py.

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