'cycles' 검색 결과

Resolve the architecture of focal oncogene amplifications — extrachromosomal DNA (ecDNA), breakage-fusion-bridge (BFB) cycles, homogeneously staining regions (HSR), and linear amplification — from whole-genome sequencing with AmpliconArchitect, the AmpliconSuite pipeline, and AmpliconClassifier. Covers copy-number seed selection, breakpoint-graph reconstruction, balanced-flow optimization, ecDNA classification, and the limits of depth-only amplification calls. Use when a focal amplification needs structural characterization, when distinguishing ecDNA from chromosomal amplification, suspecting ecDNA-driven oncogene amplification or therapy resistance, or selecting copy-number seeds for amplicon reconstruction.

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Use when the user hands over a GitHub issue to be delivered end to end — 'resolver a issue #42', 'loop na issue 42', 'deliver issue https://github.com/o/r/issues/42' — or when an Orca worker preamble dispatches `feat-loop #N`. Turns the issue into a plan, executes it, reviews the result and runs at most 2 fix cycles until APPROVED, then opens a pull request that closes the issue. Never merges. Do NOT use without an issue (feat-feature / feat-quick), to only plan (feat-feature), to only review (feat-review) or to execute an existing plan (feat-exec).

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Author pull requests with intent-separated commits, blast-radius disclosure, and verification evidence. Load when opening a PR, writing a PR description, separating refactor from feature commits, or summarizing a change set for review. Also triggers on "write the PR", "PR body", "intent-separated commits", "split refactor from feature", "pr summary", or after safe-change cycles complete. Extends git-workflow-and-versioning — does not replace it.

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Prioritizes rare-disease variants from trio/quad WES/WGS with de novo (DeNovoGear, Triodenovo), compound-heterozygous phasing (WhatsHap), mosaic VAF tiering, phenotype-driven ranking (Exomiser, Phen2Gene, AMELIE), ClinGen gene-disease validity gating, and ACMG SF v3.2 secondary findings reporting. Use when running diagnostic exome / genome pipelines, identifying candidate Mendelian disease genes, screening for incidental findings, or auditing VUS reclassification cycles. The ACMG/AMP classification framework (PVS1 decision tree, Pejaver PP3/BP4 calibration, Tavtigian point system) is in clinical-databases/acmg-classification.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Resolve the architecture of focal oncogene amplifications — extrachromosomal DNA (ecDNA), breakage-fusion-bridge (BFB) cycles, homogeneously staining regions (HSR), and linear amplification — from whole-genome sequencing with AmpliconArchitect, the AmpliconSuite pipeline, and AmpliconClassifier. Covers copy-number seed selection, breakpoint-graph reconstruction, balanced-flow optimization, ecDNA classification, and the limits of depth-only amplification calls. Use when a focal amplification needs structural characterization, when distinguishing ecDNA from chromosomal amplification, suspecting ecDNA-driven oncogene amplification or therapy resistance, or selecting copy-number seeds for amplicon reconstruction.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Manage DAG execution lifecycles including start, stop, pause, resume, and cleanup. Activate on 'execution lifecycle', 'stop execution', 'abort DAG', 'graceful shutdown', 'kill process'. NOT for cost estimation, DAG building, or skill selection.

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Analyze hierarchical DAG-like systems by separating undirected substrate from ordering metadata, then classifying diamonds, mixers, shortcuts, and hidden cycle structure. Use for workflow architecture, citation or genealogy DAG comparison, and information-flow diagnosis. NOT for ordinary cycle detection in arbitrary graphs, one-node runtime debugging, or systems with no real ordering constraint.

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Create comprehensive academic research notes with deep literature coverage. Auto-detects language (EN prompt→EN output, TR prompt→TR output). Supports Obsidian markdown and PDF. Performs 8-15 iterative search cycles with 25-50+ sources for comprehensive coverage. Uses footnote citations and visual overviews.

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Quality assurance review for implementations. Use when reviewing code quality, checking implementation standards, performing QA cycles, or validating feature quality.

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Tracks complex, multi-session work using the Beads issue tracker and dependency graphs, and provides persistent memory that survives conversation compaction. Use when work spans multiple sessions, has complex dependencies, or needs persistent context across compaction cycles. Trigger with phrases like "create task for", "what's ready to work on", "show task", "track this work", "what's blocking", or "update status".

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Professional Ziwei Doushu consultation skill with offline, Beijing-standard calculation rules. Use when the user wants a polished Ziwei report from birth date and time, including life palace structure, twelve palaces, four transformations, major luck cycles, yearly triggers, optional chart images, and a clear split between chart facts and traditional interpretation.

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Build and run multi-agent content production teams on OpenClaw with single-repo architecture, symlink-based file sharing, role-specialized AGENTS.md, and automated review-fix-score loops. Use when: (1) Setting up a team of 3+ agents with writer/reviewer/scorer/fixer roles for content creation, (2) Creating a quality-controlled publishing pipeline, (3) Bootstrapping agent workspaces with symlinks and tool configs from scratch, (4) Running multi-round review→fix→score cycles until a quality threshold is met, (5) Debugging agent spawn permissions, tool-call loops, or symlink issues. Based on real production experience building a 6-agent content team (2026-03-30).

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Orchestrate multi-agent teams with defined roles, task lifecycles, handoff protocols, and review workflows. Use when: (1) Setting up a team of 2+ agents with different specializations, (2) Defining task routing and lifecycle (inbox → spec → build → review → done), (3) Creating handoff protocols between agents, (4) Establishing review and quality gates, (5) Managing async communication and artifact sharing between agents.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Strategic account planning and execution for enterprise deals. Use when planning complex sales cycles, managing multiple stakeholders, applying MEDDICC qualification, tracking deal health, or building mutual action plans. Includes the "stale MAP equals dead deal" pattern.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Create, edit, fix, or explain Mermaid diagrams for relationships, decision branches, interactions, lifecycles, and data models; also use when the parent selects a diagram to materially clarify an explanation. Do not trigger for simple status, one fact, short lists, quantitative charts, or marketing slides.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Expert in LangGraph - the production-grade framework for building stateful, multi-actor AI applications. Covers graph construction, state management, cycles and branches, persistence with checkpointers, human-in-the-loop patterns, and the ReAct agent pattern. Used in production at LinkedIn, Uber, and 400+ companies. This is LangChain's recommended approach for building agents. Use when: langgraph, langchain agent, stateful agent, agent graph, react agent.

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Complete OKR & Strategy Execution system — from company vision to weekly execution. Covers goal hierarchy, OKR writing methodology, scoring rubrics, alignment cascading, KPI dashboards, review cadences, team accountability, and quarterly planning rituals. Use when setting goals, running planning cycles, tracking OKRs, building KPI dashboards, running retrospectives, or aligning team work to strategy. Trigger on: "OKR", "objectives", "key results", "goal setting", "quarterly planning", "KPIs", "strategy execution", "annual planning", "team goals", "alignment", "review cadence", "what should we focus on", "prioritize", "goal tracking", "north star metric".

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Create polished, validated architecture, workflow, sequence, data-flow, and lifecycle/state diagrams as explorable standalone HTML with inline SVG, dark/light themes, optional trace motion, and PNG/JPEG/WebP/SVG/WebM export. Accept plain-language requirements or pasted Mermaid flowchart, sequenceDiagram, and stateDiagram input; inspect repository evidence when the diagram must reflect real code. Use when the user asks to visualize system architecture, infrastructure, cloud/security/network topology, technical workflows, API call sequences, request lifecycles, data pipelines, ETL/ELT, data lineage, state machines, or to convert/beautify Mermaid.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.