'synthesis' 검색 결과

Run programmatic Tavily search and extraction while filtering raw results outside the main agent context. Use for multi-step or high-volume research where titles, snippets, and selected passages should be curated before synthesis.

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Run Tavily's multi-source research workflow for comparisons, market analysis, literature-oriented exploration, or detailed cited reports. Use only when bounded search and extraction are insufficient.

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Current external research using available web tools, primary sources where possible, links/citations, date awareness, synthesis, and unresolved uncertainty.

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Expert in building voice AI applications - from real-time voice agents to voice-enabled apps. Covers OpenAI Realtime API, Vapi for voice agents, Deepgram for transcription, ElevenLabs for synthesis, LiveKit for real-time infrastructure, and WebRTC fundamentals. Knows how to build low-latency, production-ready voice experiences. Use when: voice ai, voice agent, speech to text, text to speech, realtime voice.

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Voice agents represent the frontier of AI interaction - humans speaking naturally with AI systems. The challenge isn't just speech recognition and synthesis, it's achieving natural conversation flow with sub-800ms latency while handling interruptions, background noise, and emotional nuance. This skill covers two architectures: speech-to-speech (OpenAI Realtime API, lowest latency, most natural) and pipeline (STT→LLM→TTS, more control, easier to debug). Key insight: latency is the constraint. Hu

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Comprehensive toolkit for product managers including RICE prioritization, customer interview analysis, PRD templates, discovery frameworks, and go-to-market strategies. Use for feature prioritization, user research synthesis, requirement documentation, and product strategy development.

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Technical research methodology with YAGNI/KISS/DRY principles. Phases: scope definition, information gathering, analysis, synthesis, recommendation. Capabilities: technology evaluation, architecture analysis, best practices research, trade-off assessment, solution design. Actions: research, analyze, evaluate, compare, recommend technical solutions. Keywords: research, technology evaluation, best practices, architecture analysis, trade-offs, scalability, security, maintainability, YAGNI, KISS, DRY, technical analysis, solution design, competitive analysis, feasibility study. Use when: researching technologies, evaluating architectures, analyzing best practices, comparing solutions, assessing technical trade-offs, planning scalable/secure systems.

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Deep multi-source research synthesis — web, academic, patent, and internal KB cross-referencing

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Turn the current conversation into a PRD and publish it to the project issue tracker — no interview, just synthesis of what you've already discussed.

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Synthesize scientific evidence into a claim-to-source matrix, distinguish primary evidence from interpretation, assess disagreement and study limitations, and produce a calibrated research summary.

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Meta-analysis / evidence synthesis — pool effect sizes across studies (odds ratios, risk ratios, hazard ratios, mean differences, correlations, GWAS betas) with fixed- or random-effects models, quantify heterogeneity (Q, I², τ²), and build a forest plot. Use when you have results from MULTIPLE studies and need a single pooled estimate, or to synthesize evidence from a systematic review / multiple GWAS / replicated experiments. Handles the error-prone effect-size + standard-error preparation (converting OR/HR/CI, two-group means±SD, proportions, and correlations into the (effect, SE) the pooling step needs).

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Deep literature review — PubMed, EuropePMC, bioRxiv preprints, citation networks, evidence synthesis. Disambiguates queries, runs collision-aware searches, grades evidence T1-T4, and produces structured reports. Use for systematic literature review, meta-analysis evidence collection, and detailed answer-with-citations workflows.

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Find commercial sources for chemical compounds — PubChem/ChEMBL identity resolution then vendor catalog search across ZINC, Enamine, eMolecules, Mcule. Compares pricing, availability, and identifies purchasable analogs when an exact compound is not in stock. Use for chemical procurement, virtual library curation, and 'where can I buy X' questions for synthesis planning.

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PyTorch-native graph neural networks for molecules and proteins. Use when building custom GNN architectures for drug discovery, protein modeling, or knowledge graph reasoning. Best for custom model development, protein property prediction, retrosynthesis. For pre-trained models and diverse featurizers use deepchem; for benchmark datasets use pytdc.

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Organic chemistry reasoning guide for reaction product prediction, mechanism analysis (electrophilic/nucleophilic substitution, addition, elimination, pericyclic, radical), and spectroscopy interpretation (1H/13C NMR, IR, MS). Reasons from first principles (electron flow, kinetic vs thermodynamic) rather than pattern-matching named reactions. Use for organic synthesis problems and mechanism explanations.

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Search academic literature and generate, validate, or compare Knows paper sidecars. Use for claim/evidence analysis and literature synthesis.

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The live fieldwork layer for psycho-logic — go look at the actual target market NOW instead of reasoning from your training-data stereotype of it. Use when a psycho-logic move needs grounding in a specific place: the user asks 'what do competitors in [region/country] actually do', 'what's the real price band / norm here', 'how do local leaders position themselves', 'research this market before we localise', 'what signals trust to buyers in X', or is about to launch/adapt in a market you haven't studied. Runs structured web research in the local language — local competitors and their signals, price bands, category conventions, review/trust sources, local terminology, taboos and regulations — and synthesises a compact perception profile the four moves consume. Inspired by Rory Sutherland's *Alchemy*. Routed to from psycho-logic; pair with cultural-context (the lens that tells you what to look for). 日本語・中文の相談（「現地の実態を調べて」「调研当地市场」）にも使う。

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週ごとに Notion「ナレッジカード」DB に集まったカードを読み、問いをまたいで親和図にまとめ、正（worked）と反（failed）の対立から合（提案）を出し、次の問いを決めて、「合成テーマ」DB と週の行の配下の「まとめ」ページに書き込む。「今週のカードを合成して」「W43 のまとめを作って」「ナレッジカードの合成」などの依頼で使う。カードの提出は knowledge-cards、個人の採点は evaluate-session の領域。個人別の件数ランキングや「誰が何を失敗した」は出さない。

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Designs and analyzes pooled prime-editor (PE) screens for installing precise genetic variants without bystander confounding. Covers pegRNA design with PRIDICT and PRIDICT2 (Mathis 2023/2024) for predicting per-pegRNA editing efficiency, pegRNA architecture (spacer + scaffold + PBS + RTT), PE2 / PE3 / PE3b / PEmax / PEAR variants, MOSAIC in situ saturation mutagenesis (Hsu JY et al 2024 bioRxiv), the PRIME pooled-screen methodology (Erwood/Doman 2023 Nat Biotechnol 41:885; ~3,699 ClinVar variant screens), chromatin context as a primary determinant of PE efficiency, scaffold-incorporation and indel byproduct quantification with CRISPResso2, and the cross-modal validation strategy of PE + base-editor screens for variant function. Use when designing a pegRNA library for variant installation, choosing between BE and PE for a specific edit, predicting pegRNA efficiency before library synthesis, analyzing PE screen output, distinguishing intended-edit from scaffold-incorporation, or scaling PE screens to thousands of variants.

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Capture the "why" behind technical choices to prevent architectural drift. Load when the user makes a major technical decision, chooses a library/framework, defines a system boundary, or changes a core architectural pattern. Also triggers on "record a decision", "write an ADR", "why did we do this", "document this architectural choice", or "architectural decision record". Supports `SYNTHESIS=true` mode for retrospective ADR backfill from observed repo state — used by `retroactive-project-setup` and any future backfill skill. Essential for long-term project maintainability and agent alignment.

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Search real-time news with bias scoring, get live stock/ETF/crypto data with AI analysis, ML options pricing, balanced news synthesis, and meme search via the Helium MCP server.

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Designs and analyzes pooled prime-editor (PE) screens for installing precise genetic variants without bystander confounding. Covers pegRNA design with PRIDICT and PRIDICT2 (Mathis 2023/2024) for predicting per-pegRNA editing efficiency, pegRNA architecture (spacer + scaffold + PBS + RTT), PE2 / PE3 / PE3b / PEmax / PEAR variants, MOSAIC in situ saturation mutagenesis (Hsu JY et al 2024 bioRxiv), the PRIME pooled-screen methodology (Erwood/Doman 2023 Nat Biotechnol 41:885; ~3,699 ClinVar variant screens), chromatin context as a primary determinant of PE efficiency, scaffold-incorporation and indel byproduct quantification with CRISPResso2, and the cross-modal validation strategy of PE + base-editor screens for variant function. Use when designing a pegRNA library for variant installation, choosing between BE and PE for a specific edit, predicting pegRNA efficiency before library synthesis, analyzing PE screen output, distinguishing intended-edit from scaffold-incorporation, or scaling PE screens to thousands of variants.

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Build audio transcription pipelines with Whisper, Deepgram, and AssemblyAI including speaker diarization and real-time streaming. Activate on: transcription, speech-to-text, diarization, audio processing, meeting transcripts. NOT for: text-to-speech synthesis (voice-audio-engineer), music generation (ai-engineer).

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Track the full Toulmin epistemic ancestry of every claim produced by a multi-agent swarm. Each agent output is tagged with an argument chain (claim / data / warrant / relationship) derived from SwarmTracer spans and LineageEdge records, so operators can zoom into any sub-claim and see precisely which agents asserted it, what triggered each assertion, and how contradictions propagated or were synthesised away. The SwarmTracer pattern — wrapping the SwarmAgentExecutor to capture spans, record messages, and build a lineage graph — is the concrete runtime substrate. Argumentative lineage lifts that graph into the Toulmin vocabulary so reasoning provenance is both machine-queryable and human-interpretable.

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