'oss' 검색 결과

Detect single-nucleotide crosslink (CL) sites in CLIP-seq data using truncation patterns (iCLIP/eCLIP CITS), crosslink-induced mutations (HITS-CLIP CIMS deletions, PAR-CLIP T-to-C), or HMM/kernel-density methods (PureCLIP, PARalyzer, CTK). Use when single-nucleotide resolution is required for motif registration (mCross), allele-specific binding (BEAPR), variant-effect prediction, or comparing crosslink chemistry across CLIP variants.

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Discover RBP binding motifs from CLIP-seq peaks or single-nucleotide crosslink sites using HOMER, MEME/STREME, kpLogo, mCross (CL-position-registered motifs), PEKA (positional k-mer enrichment), RBPamp (affinity), and RNA Bind-n-Seq (RBNS) cross-validation. Use when characterizing RBP sequence specificity, registering motifs to crosslink positions, validating in vivo CLIP motifs against in vitro RBNS Kd, reconciling motif disagreements across tools, or correcting for the uracil crosslinking bias that contaminates raw CLIP motif logos.

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Detect single-nucleotide crosslink (CL) sites in CLIP-seq data using truncation patterns (iCLIP/eCLIP CITS), crosslink-induced mutations (HITS-CLIP CIMS deletions, PAR-CLIP T-to-C), or HMM/kernel-density methods (PureCLIP, PARalyzer, CTK). Use when single-nucleotide resolution is required for motif registration (mCross), allele-specific binding (BEAPR), variant-effect prediction, or comparing crosslink chemistry across CLIP variants.

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Discover RBP binding motifs from CLIP-seq peaks or single-nucleotide crosslink sites using HOMER, MEME/STREME, kpLogo, mCross (CL-position-registered motifs), PEKA (positional k-mer enrichment), RBPamp (affinity), and RNA Bind-n-Seq (RBNS) cross-validation. Use when characterizing RBP sequence specificity, registering motifs to crosslink positions, validating in vivo CLIP motifs against in vitro RBNS Kd, reconciling motif disagreements across tools, or correcting for the uracil crosslinking bias that contaminates raw CLIP motif logos.

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Detect single-nucleotide crosslink (CL) sites in CLIP-seq data using truncation patterns (iCLIP/eCLIP CITS), crosslink-induced mutations (HITS-CLIP CIMS deletions, PAR-CLIP T-to-C), or HMM/kernel-density methods (PureCLIP, PARalyzer, CTK). Use when single-nucleotide resolution is required for motif registration (mCross), allele-specific binding (BEAPR), variant-effect prediction, or comparing crosslink chemistry across CLIP variants.

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Review cross-origin isolation, a browser security mode required by features such as SharedArrayBuffer. Check response headers and external resources, identify integrations that could break, and verify that isolation actually works in the browser.

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• Checking isolation requirements for SharedArrayBuffer
• Auditing external resources before enabling COEP
• Reviewing effects on popups and third-party embeds

Review quarterly updates and financials across portfolio companies to identify practical AI opportunities. Rank them by estimated profit impact, speed, and feasibility, then outline first steps and approaches that other companies can reuse.

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• Quarterly reviews of AI opportunities across portfolio companies
• Prioritizing companies for AI investment and operational support
• Finding ways to reuse successful AI projects across companies

Screen dependency names on npm, PyPI, and crates.io before installation to find lookalikes of legitimate packages. This skill compares spelling patterns and registry metadata, helping review AI-generated lists, lockfile changes, and new dependencies in CI/CD.

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• Screening a new dependency before installation
• Reviewing dependency lists generated by AI
• Checking lockfile changes for swapped packages

Connect security incidents across organizations by comparing attack indicators, techniques, and timelines. Build relationship graphs and campaign reports that document shared evidence, attribution confidence, and indicators useful for detection.

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• Linking incidents that share attack indicators
• Analyzing attacks across partner organizations
• Preparing reports on sustained attack campaigns

Configure Google Cloud logs across multiple projects, either by storing them centrally or querying them together where they already reside. The skill guides routing, access permissions, and log views, and helps diagnose missing logs and permission failures.

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• Collect logs from multiple projects in one central bucket
• Query distributed logs without copying their data
• Set log access boundaries by project or log type

Monitor model training through WandB metrics to detect invalid numbers, worsening loss, and declining evaluation results. Ambiguous trends receive a Codex review, while stopped runs retain key metrics and the reason for stopping.

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• Check loss and evaluation trends during model training
• Detect NaN values and diverging loss
• Review flat or noisy training metrics

Build holaOS apps for connecting external services or managing work through a dashboard. The skill uses shared SDK building blocks for stored records, actions, and synchronization, with the dashboard and agent tools working on the same data.

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• Building an external service integration
• Creating a CRM dashboard
• Building a content planning workspace

Run independent development tasks in parallel, each with a separate git worktree and implementation agent. Each agent opens its own pull request, which receives cross-review before being handed to a human for review and merging.

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• Implementing independent changes in parallel
• Assigning separate working directories to agents
• Preparing an individual pull request for each task

Build stablecoin transfers where the amount sent equals the amount received using LI.FI Intents. The skill covers quotes, token approval, escrow deposits, and order tracking for transfers within or across supported blockchains.

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• Building a stablecoin swap interface with equal input and output amounts
• Adding cross-chain USDC or USDT transfers
• Implementing quotes, approvals, and escrow orders in a backend

Find social media profiles through Google using a person’s name, brand name, or username. Collect platform names, profile links, usernames, description snippets, and follower counts where they appear in search results.

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• Find a person’s profiles across social platforms
• Collect links to a brand’s social media pages
• Find influencer profile candidates

Search for social media profiles associated with a person, brand, or business across platforms including Facebook, Twitter, Instagram, LinkedIn, and TikTok. Receive a downloadable CSV with profile links, follower counts, page titles, and description snippets.

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• Research a brand's presence across social platforms
• Find competitors' social media profiles
• Locate creators across multiple platforms

Helps implement coss UI components correctly. Use when building UIs with coss primitives (buttons, dialogs, selects, forms, menus, tabs, inputs, toasts, etc.), migrating from shadcn/Radix to coss/Base UI, composing trigger-based overlays, or troubleshooting coss component behavior. Covers imports, accessibility, Tailwind styling, and common pitfalls.

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Tax-loss harvesting strategies for A-share portfolios. Adapts the original tax-loss-harvesting skill for Chinese tax rules, A-share market conventions, and domestic tax treatment. Triggers on "A股税务亏损抵扣", "亏损抵扣", "tax loss harvesting China", "税务优化", "亏损抵扣策略", or "harvest tax losses [portfolio]".

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Harmonises data classification across jurisdictions mapping GDPR special categories vs CCPA sensitive PI (1798.140(ae)) vs HIPAA PHI (160.103) vs LGPD sensitive data (Art. 5-II). Provides cross-regulation mapping matrix for multinational compliance. Keywords: cross-jurisdiction, GDPR, CCPA, HIPAA, LGPD, sensitive data, multinational, classification mapping.

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Comprehensive expertise in cross-chain infrastructure, including LayerZero, Wormhole, Axelar, and custom bridge implementations. Covers omnichain token standards, message passing, bridge security, and cross-chain application architecture. Use when "cross-chain, bridge, LayerZero, Wormhole, Axelar, omnichain, multi-chain, chain abstraction, cross-chain messaging, token bridge, " mentioned.

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亚马逊管理之道 (亚马逊管理之道 (The Amazon Way — Amazon 自身的领导力与运营操作系统) — 这个 master skill 蒸馏的不是『在亚马逊平台上开店卖货』(那是跨境电商运营,已由 cross-border-ecommerce 另蒸),也不是 AWS 云技术架构;而是亚马逊这家公司『怎么运营自己、怎么做决策、怎么招人、怎么创新、怎么规划』的一整套可迁移的管理机制(mechanisms)与心智操作系统。面向想在自己团队/公司引入亚马逊式机制的创始人/CEO/高管/运营负责人(COO)、产品经理与技术产品经理(PM/PMT)、组织与流程设计者(chief of staff / ops)、以及在亚马逊工作或准备面试亚马逊(著名的 LP 行为面试 + Bar Raiser)的人。覆盖: (a) 第一性张力 — 亚马逊 OS 的核心世界观分歧: **机制 > 良好意图(Good intentions don't work, mechanisms do:问题不能靠『下次更努力』修复,要装一个带检查闭环的自我强化流程) ⇄ 可控输入指标 vs 滞后输出指标(管你能控制的 input 如选品/价格/在库/配送速度,而非 revenue/股价这类滞后又不可控的 output) ⇄ 长期主义 vs 季度业绩(Day 1、willing to be misunderstood、用现金流+飞轮长期投入,宁可牺牲短期利润) ⇄ 客户执念 vs 竞争对手执念(working backwards 从客户倒推,而非从竞品或『我们能造什么』正推) ⇄ 叙事备忘录 vs PPT(6-pager + 开会前静默阅读、动手前先写 PR/FAQ;写作逼出清晰思考,禁 PowerPoint) ⇄ 单线程负责人/两个披萨团队 vs 协调税(separable、autonomous、one owner per initiative,砍掉跨团队依赖) ⇄ 高标准可学习可传递 vs 与生俱来(insist on the highest standards + Bar Raiser 招聘门,标准是 domain-specific 且能教的) ⇄ 节俭催生创造力 vs 血汗文化(frugality/约束驱动发明 —— 但 frugality + 高压 bar + URA 强制淘汰 = 文化阴暗面批判) ⇄ 两类决策(Type 1 不可逆/单向门 慎重 vs Type 2 可逆/双向门 高判断力个人快速决策,别用重流程拖慢))**; (b) 核心机制(mechanisms,本行的『工具栈』其实是一套运营机制而非软件) — Leadership Principles(14 条→2021 增至 16 条,是一套运营语言和决策仲裁器)、Working Backwards(从客户倒推:动手前先写新闻稿+常见问答 PR/FAQ)、叙事备忘录(6-pager narrative / 1-pager + silent reading 静默阅读、禁 PPT)、Weekly Business Review(WBR + metrics deck 指标看板)、input/output metrics(可控输入指标体系、DMAIC 式指标选择)、年度规划(OP1/OP2 + S-Team goals)、Bar Raiser(招聘机制,独立于用人经理的抬杠者拥有一票否决)、Two-Pizza Team / Single-Threaded Leader STL / separable teams、Correction of Errors(COE 事故复盘 + 5 Whys 五问法)、Andon Cord(安灯绳,借自丰田,一线可拉停)、Flywheel(飞轮:低价→更多客户→更多卖家→更多选品→更低成本结构→更低价)、Type 1/Type 2(单向门/双向门决策分级)、Regret Minimization Framework(遗憾最小化,贝索斯创业决策法); (c) 心智模型层 — customer obsession(客户执念是所有 LP 之首)、long-term thinking / Day 1(第二天就是停滞衰亡)、invent and simplify、ownership(主人翁,不说 that's not my job)、bias for action(可逆决策就快,speed matters)、disagree and commit(充分反对后即便不同意也全力执行)、frugality、dive deep(深入细节、不靠代理指标脱离一线)、think big、are right a lot(用强判断力和证伪自己的能力多做对的判断)、earn trust、deliver results; (d) 工作流/SOP — 用亚马逊方式发起一个新产品/业务(先写 PR/FAQ→评审→倒推着造)、如何跑一场 WBR、如何写和评审一份 6-pager(叙事流程 + 静默阅读)、Bar Raiser 招聘 loop、年度规划(OP1/OP2→S-Team goals→输入指标追踪)、事故后的 Correction of Errors; (e) 知识正典(en-primary,极其丰富且可取一手) — 贝索斯致股东信 1997-2021(1997 首封是奠基文本,每年附在信末;Day 1、遗憾最小化、long term)、《Working Backwards》Colin Bryar & Bill Carr(2021,运营机制圣经)、《The Everything Store》Brad Stone(2013,公司史)、《Amazon Unbound》Brad Stone(2021,权力与阴暗面续作)、《Invent and Wander》贝索斯文集(2020)、《The Amazon Way》/《Think Like Amazon》John Rossman(前亚马逊高管)、Amazon 官方 Leadership Principles 页(amazon.jobs,一手)、HBR『The Institutional Yes』(2007 贝索斯访谈); (f) 行业大佬/figures — Jeff Bezos(创始人,源头教义)、Andy Jassy(现任 CEO,OS 超越创始人的证据 + AWS 缔造者)、Colin Bryar(前贝索斯影子/TPM,《Working Backwards》作者)、Bill Carr(前数字媒体 VP,《Working Backwards》作者)、Jeff Wilke(前全球消费者 CEO,运营架构师)、John Rossman(前亚马逊、机制布道者/顾问)、Brad Stone(记者/编年史作者,批判性外部视角); (g) 争议/批判(必须保留,不能洗白) — 文化阴暗面(NYT 2015『Inside Amazon: Wrestling Big Ideas in a Bruising Workplace』揭露高压职场)、仓储与一线劳工争议、URA(unregretted attrition 强制淘汰)与 stack-ranking 的残酷、frugality + 高 bar = 燃尽(burnout);机制能否迁出亚马逊(cargo-culting:在初创或非科技公司照搬 PR/FAQ/输入指标/Bar Raiser 常失败);是贝索斯个人天才(personality)还是制度化机制(institution)—— OS 在贝索斯卸任后于 Jassy 治下延续,是机制派的证据; (h) 流派/思想谱系 — **信徒/机制布道派(Bryar & Carr《Working Backwards》+ 前亚马逊 operator 顾问圈,信 mechanisms 可移植、任何公司可安装)** vs **批判派(Brad Stone《Amazon Unbound》+ NYT + 劳工视角,认为 OS 与高淘汰的残酷机器不可分割,不该被浪漫化)** vs **情境/规模怀疑派(机制之所以有效是因为亚马逊特定的规模/现金流/创始人权力,照搬到小公司=cargo cult)** vs **创始人中心 vs 制度中心之争(是贝索斯个人 vs 可传承的机制)**。不含: 在亚马逊开店卖货/选品/PPC/FBA 的卖家运营(=cross-border-ecommerce)、AWS 云技术架构与运维、通用 MBA 管理理论泛泛而谈、把普通商业常识包装成『亚马逊独家秘诀』。) Master OS — automated mastery of 亚马逊管理之道 (The Amazon Way — Amazon 自身的领导力与运营操作系统) — 这个 master skill 蒸馏的不是『在亚马逊平台上开店卖货』(那是跨境电商运营,已由 cross-border-ecommerce 另蒸),也不是 AWS 云技术架构;而是亚马逊这家公司『怎么运营自己、怎么做决策、怎么招人、怎么创新、怎么规划』的一整套可迁移的管理机制(mechanisms)与心智操作系统。面向想在自己团队/公司引入亚马逊式机制的创始人/CEO/高管/运营负责人(COO)、产品经理与技术产品经理(PM/PMT)、组织与流程设计者(chief of staff / ops)、以及在亚马逊工作或准备面试亚马逊(著名的 LP 行为面试 + Bar Raiser)的人。覆盖: (a) 第一性张力 — 亚马逊 OS 的核心世界观分歧: **机制 >

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Analyze sales-call transcripts to extract why deals are won and lost across six dimensions — product, messaging, GTM/sales, pricing, competition, and customer context. Produces aggregated patterns with verbatim buyer quotes, frequencies, and recommendations. Writes to marketing/win-loss/win-loss.md as the evidence base under positioning, messaging, and ICP. Triggers - "win loss analysis", "why are we losing deals", "why do we win", "analyze sales calls", "churn analysis", "deal review"

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Plan and execute your second and third contributions to become a regular contributor. Covers relationship building, progressive complexity escalation, and community presence. Use when your first PR was merged and you want to keep contributing, when transitioning from one-off contributor to regular, or when planning a sustained OSS involvement. Not for your first contribution — use the oss-find-issue → oss-contribute chain for that.

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Prepare to contribute to an open source repo. Reads all contribution docs, checks eligibility, assesses the user's knowledge gaps, and fills them before coding starts. Use after finding an issue with oss-find-issue, or when starting work on any OSS repo. Not for installing dependencies or getting the build and tests running. Use oss-setup-dev-env for that.

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