'experiments' 검색 결과

"Apply Difference-in-Differences (DID) to estimate causal treatment effects by comparing changes in outcomes between treatment and control groups. Use this skill when the user evaluates policy interventions, natural experiments, or regulatory changes, needs to test parallel trends, or when they ask 'did this policy work', 'how do I identify causal effects without randomization', or 'what is the treatment effect'.".

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"Design and analyze factorial experiments to identify significant process factors and optimize settings. Use this skill when the user needs to systematically test factor effects, optimize a manufacturing process, or determine which variables matter most — even if they say 'which factors affect quality', 'optimize process settings', or 'design an experiment'.".

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Design rigorous experiments — hypotheses, controls, randomization, power analysis, and preregistration. Use when planning any study where you need trustworthy causal conclusions.

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Designing psychology experiments — variables, controls, randomization, counterbalancing, and preregistration.

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Chaos engineering — designing safe failure-injection experiments to build resilience — use when proactively testing system robustness.

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Design rigorous A/B test plans with hypothesis, sample size calculation, Minimum Detectable Effect (MDE), randomization strategy, and decision rules. Includes guardrail metrics and rollout playbook. Use when planning product experiments, conversion optimization, or data-driven feature decisions.

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Use when adding, reviewing, or repairing Pharos Worker cron schedules, slot dispatch, leases, or runtime experiments.

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Design, analyze, and document A/B tests for conversion, onboarding, pricing, lifecycle, and product experiments. Use when the user asks for `/ab-test-setup`, experiment design, sample size, statistical significance, A/B test analysis, ICE-scored test backlogs, or avoiding common testing mistakes.

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实验、评价与诊断；适用于实证型 CS 会议论文，按当前任务加载。

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Design and analyze engineering experiments or simulations using baseline cases, hypothesis-driven DOE, traceable data processing, defensible plots, uncertainty, and validation. Use for CFD, laboratory data, ML workflows, parameter studies, or research code.

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Analyze thermal-fluid engineering systems, experiments, CFD, and correlations with explicit assumptions, validity limits, uncertainty, and mechanism-based interpretation. Use for heat transfer, fluid mechanics, phase change, HVAC, energy systems, turbomachinery, piping, or thermal management.

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Iterative manuscript improvement workflow where a reviewer agent critiques, an author agent revises, a verifier checks the revision, and the loop repeats until acceptance or a human-pause condition is reached. Use for virtual peer review, reviewer-author revision loops, rebuttal preparation, resubmission polishing, journal paper improvement, response-to-reviewers drafting, and deciding when additional data, experiments, theory, modeling, or author judgment is required before further revision.

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Apply source-aware mechanical-engineering judgment to research, analysis, coding, writing, teaching, research identity, and release work. Use for thermal-fluid systems, heat transfer, fluid mechanics, thermodynamics, HVAC, energy systems, turbomachinery, piping, multiphase flow, experiments, correlations, CFD, reduced-order models, AI/ML, uncertainty, engineering datasets, literature reviews, citations, manuscripts, reviewer revisions, Overleaf packages, figures, proposals, research software, reproducibility, public releases, engineering teaching materials, or a research-project logo and visual identity.

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Design product experiments to test hypotheses. Use when the user says "run an experiment", "A/B test this", "build-measure-learn", "validate this assumption", "test this hypothesis", "we don't know if this will work", "minimum viable test", "lean experiment", or wants to reduce risk before fully building a feature - even if they don't explicitly say "experiment". For sample sizes, power calculations and significance testing, use ab-test-design instead.

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Build comprehensive chromatin contact maps by aggregating Hi-C loop calls (BEDPE) across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "what regions are in 3D contact in my tissue?" by creating a union catalog of chromatin loops. Handles resolution-aware anchor matching, cross-lab variation, and Hi-C-specific quality metrics.

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Guide for integrating CellxGene Census single-cell data with ENCODE bulk experiments. Use when users need cell-type-specific expression context for ENCODE regulatory data, want to deconvolve bulk ENCODE signals, or validate regulatory elements at single-cell resolution. Trigger on: CellxGene, single-cell atlas, cell type expression, Census, cell type specificity, single-cell context, scRNA-seq atlas.

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Download ENCODE genomics files (BED, FASTQ, BAM, bigWig, etc.) to the user's machine. Use when the user wants to download data files from ENCODE experiments.

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Compare ENCODE experiments across different biosamples, tissues, or cell lines to identify tissue-specific regulatory patterns. Use when the user wants cross-tissue comparison, cell-type comparison, tissue-specific elements, differential chromatin, biosample matching, disease vs normal comparison, developmental time course, constitutive vs variable regulation, or multi-tissue data availability mapping. Handles batch effect detection, biosample hierarchy, and comparison design.

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Search and explore ENCODE Project genomics data. Use when the user wants to find experiments, files, or explore what data is available for specific assays, organs, cell lines, or targets.

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Cross-reference ENCODE data with PubMed, bioRxiv, ClinicalTrials.gov, Open Targets, GTEx, ClinVar, GWAS Catalog, gnomAD, Ensembl, and other scientific databases. Use when the user wants to find publications, preprints, or clinical trials related to ENCODE experiments, chain ENCODE data with other scientific MCP servers, or build translational pipelines from genomic data to clinical application.

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Build comprehensive chromatin accessibility maps by aggregating ATAC-seq and DNase-seq narrowPeak data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is chromatin accessible in my tissue?" by combining peak calls into a union peak set. Handles cross-lab variation, ATAC vs DNase platform differences, and ENCODE blocklist filtering.

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Find and work with ENCODE single-cell genomics data including scRNA-seq and scATAC-seq. Use when the user asks about single-cell experiments, cell type resolution, clustering from ENCODE data, deconvolution of bulk signals using single-cell references, or comparing single-cell vs bulk profiles. Covers platform differences (10X Chromium, Smart-seq2, Drop-seq), quality limitations of single-cell data, multimodal integration (RNA+ATAC), and cross-study reproducibility concerns. Also use for cell type annotation, gene detection limits, dropout artifacts, and single-cell data structure in ENCODE.

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Build comprehensive histone mark maps by aggregating narrowPeak data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is this histone mark present in my tissue?" by combining peak calls from multiple studies into a union peak set with confidence annotations. Handles cross-lab batch effects, broad vs narrow marks, and ENCODE blocklist filtering.

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Build comprehensive DNA methylation maps by aggregating WGBS (Whole Genome Bisulfite Sequencing) data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is DNA methylated/unmethylated in my tissue?" by combining per-CpG methylation data into tissue-level methylation profiles. Handles coverage filtering, identifies hypomethylated regions (HMRs) and partially methylated domains (PMDs), and manages cross-lab variation.

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