593건 · 관련도순
Pair a source-faithful photographic upper panel with a small source-derived dry-brush illustration surrounded by generous paper whitespace below. Use for 摄影加极简手绘、上下双联艺术海报、photo and miniature illustration diptychs or quiet photo-poetry prints.
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Verifies specified behavior through appropriate tests and truthful coverage reports.
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Govern FriendlyBet agent values, professional standards, anti-hallucination behavior, truthfulness, risk reporting, AI resource discipline, feedback loops, skill improvement, performance reviews, decision-rights hygiene, and team quality. Use when creating, reviewing, promoting, correcting, or retiring agents; reducing hallucinations or mistakes; reviewing AI/tool usage; handling agent incidents; or aligning work with Eyal's philanthropic user-first approach.
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Track and visualize ML training experiments with Trackio. Use when logging metrics during training (Python API), firing alerts for training diagnostics, or retrieving/analyzing logged metrics (CLI). Supports real-time dashboard visualization, alerts with webhooks, HF Space syncing, and JSON output for automation.
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Run evaluations for Hugging Face Hub models using inspect-ai and lighteval on local hardware. Use for backend selection, local GPU evals, and choosing between vLLM / Transformers / accelerate. Not for HF Jobs orchestration, model-card PRs, .eval_results publication, or community-evals automation.
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Build, deploy, and maintain applications on Hugging Face Spaces — Gradio / Docker / Static SDKs, ZeroGPU and dedicated hardware, model loading, debugging, buckets, inference providers, community grants. Use whenever the user asks to create or host an app on Hugging Face, port code onto ZeroGPU, fix a Space that won't build or run, or otherwise work with `hf spaces …`, `@spaces.GPU`, Space README frontmatter, or the `spaces` Python package.
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Guide for the Tinker CLI — managing training runs, checkpoints, downloading weights, and publishing to HuggingFace. Use when the user asks about CLI commands, listing runs, managing checkpoints from the terminal, or uploading to HF Hub.
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Busabase-backed App-in-Skill money ledger for aggregating Mercury, Stripe, Airwallex, and Creem accounts into a read-only dashboard. Use when the user invokes $kelly-money or /kelly-money, wants a total cashflow ledger, account columns, Accounts sidebar, Account Detail views, finance onboarding, connector setup, transaction import/sync, reconciliation, balances, payouts, payments, fees, refunds, transfers, or a review of money movement across these providers.
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Build, maintain, and run conformance tests for canonical App-in-Skill projects created by kelly-app-skill-creator. Use when a Kelly app skill needs contract checks, local server smoke tests, responsive browser acceptance, temporary open-source Busabase integration, environment-gated Busabase Cloud OAuth verification, lazy provisioning checks, persistence tests, AirApp parity tests, or CI coverage. Keep app creation in kelly-app-skill-creator and own only the reusable test harness, per-skill fixtures, execution gates, diagnostics, and truthful pass/fail/skip reporting.
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React (UI ライブラリ本体, react / react-dom 19.3) の公式リファレンス。 Hooks (useState, useEffect, useActionState, useOptimistic, useEffectEvent), use, cache, Suspense, Activity, ViewTransition, createRoot, hydrateRoot, createPortal, flushSync, react-dom/server, Server Components / Server Functions, React Compiler, eslint-plugin-react-hooks, DevTools, Rules of React。React Router・Next.js・TanStack 系・RHF とは別。
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Expert guidance for GRPO/RL fine-tuning with TRL for reasoning and task-specific model training
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Evaluates LLMs across 60+ academic benchmarks (MMLU, HumanEval, GSM8K, TruthfulQA, HellaSwag). Use when benchmarking model quality, comparing models, reporting academic results, or tracking training progress. Industry standard used by EleutherAI, HuggingFace, and major labs. Supports HuggingFace, vLLM, APIs.
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Evaluate LLM outputs using frontier models as judges. Use for pairwise model comparison, quality scoring with custom rubrics, and automated evaluation pipelines. Covers position bias mitigation, statistical significance, and generating preference data for DPO/RLHF.
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Performs retrosynthetic planning using AiZynthFinder (MCTS, template-based), Chemformer (template-free transformer), ASKCOS, and emerging RetroSynFormer with explicit handling of route scoring, building-block availability (eMolecules, Enamine, Mcule), forward prediction validation (Molecular Transformer), and disconnection-aware multi-objective search (MO-MCTS). Use when assessing synthetic feasibility of generated or selected molecules, planning multi-step syntheses, building synthesis-aware design pipelines, or screening libraries for retro-route feasibility.
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Calculates molecular fingerprints (ECFP/Morgan, FCFP, MACCS, RDKit, AtomPair, TopologicalTorsion, Avalon, MAP4, MHFP6) and physicochemical descriptors (Lipinski, QED, TPSA, Crippen LogP, 3D shape) with explicit choice tables, bit vs count semantics, and partial-charge model selection. Use when featurizing molecules for similarity, QSAR, virtual screening, or ML, or selecting the correct fingerprint for a chemotype-aware task.
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Performs molecular similarity searching using Tanimoto, Tversky, Dice, and cosine coefficients on bit/count fingerprints with explicit choice rules for symmetric vs asymmetric measures, scaffold-hopping vs lead-optimization regimes, activity-cliff diagnosis, and large-library nearest-neighbor methods (BulkTanimoto, Annoy MHFP6, USRCAT). Use when ranking compounds by structural resemblance to a query, clustering libraries, finding analogs, or diagnosing activity cliffs.
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AppKit macOS UI リファレンス。Liquid Glass (NSGlassEffectView)、 NSApplication, NSWindow, NSViewController, NSView, NSMenu, NSToolbar, NSTableView, NSOutlineView, NSCollectionView, NSSplitViewController, NSTabView, NSPopover, NSOpenPanel / NSSavePanel, NSSearchField, NSControl, NSStackView, NSScrollView, Diffable Data Source, target-action, responder chain。
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Designs and ranks guide RNAs (sgRNAs) for CRISPR-Cas9/Cas12a gene knockout by scanning a target for PAM sites (NGG SpCas9, NNGRRT SaCas9, TTTV Cas12a, NG SpCas9-NG, near-PAMless SpRY), enumerating candidate spacers, applying hard filters (Pol-III TTTT terminator, 5' G, GC), ranking on-target activity with the context-appropriate model (Rule Set 2/Azimuth for U6/lentiviral, CRISPRscan for T7/embryo, DeepHF for high-fidelity variants, DeepCpf1 for Cas12a), and predicting the indel/frameshift outcome (Bae out-of-frame score, inDelphi, FORECasT, Lindel). Use when selecting sgRNAs to knock out a gene, choosing a nuclease/PAM for a constrained locus, picking which exon to target, or shortlisting guides before an off-target check. Off-target specificity, base/prime editing, and HDR donors are separate skills.
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Nominates and assesses CRISPR off-target sites genome-wide. Enumerates candidate sites by mismatch and bulge tolerance with Cas-OFFinder/CRISPRitz, ranks them with the published CFD score (SpCas9-only, relative ranker) or MIT/CRISTA/energy models, runs variant-aware screening against gnomAD/individual genomes (CRISPRme), and frames the empirical genome-wide discovery assays (GUIDE-seq, CIRCLE-seq, CHANGE-seq, DISCOVER-seq, Digenome-seq) and high-fidelity nuclease choice (HiFi Cas9, Sniper-Cas9, eSpCas9, SpCas9-HF1). Use when assessing guide RNA specificity, choosing among candidate guides, screening a therapeutic guide against population variation, or planning empirical off-target validation. Distinguishes predicted vs detected vs validated. On-target activity scoring and deaminase (Cas-independent) base/prime-editor off-targets are separate skills.
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Maps between gene identifier systems (Ensembl, Entrez, HGNC symbol, UniProt, RefSeq, MANE) using AnnotationDbi, biomaRt, mygene, pyensembl, and Ensembl REST. Encodes Ensembl version stripping with GENCODE _PAR_Y preservation, the Ziemann 2016 Excel autocorrect debacle and Bruford 2020 HGNC renames (SEPT*->SEPTIN*, MARCH*->MARCHF*, MARC*->MTARC*, DEC1->DELEC1), OCT4/POU5F1 alias resolution, biomaRt archive endpoints for release pinning, the `filters` (plural) gotcha, MANE Select for clinical reporting, cross-species orthology via Ensembl Compara / OMA / OrthoDB, and tx2gene construction for tximport. Use when converting gene IDs across systems, handling renamed symbols, building tx2gene, pinning to a specific Ensembl release for reproducibility, or mapping cross-species orthologs.
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Performs molecular similarity searching using Tanimoto, Tversky, Dice, and cosine coefficients on bit/count fingerprints with explicit choice rules for symmetric vs asymmetric measures, scaffold-hopping vs lead-optimization regimes, activity-cliff diagnosis, and large-library nearest-neighbor methods (BulkTanimoto, Annoy MHFP6, USRCAT). Use when ranking compounds by structural resemblance to a query, clustering libraries, finding analogs, or diagnosing activity cliffs.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
Calculates molecular fingerprints (ECFP/Morgan, FCFP, MACCS, RDKit, AtomPair, TopologicalTorsion, Avalon, MAP4, MHFP6) and physicochemical descriptors (Lipinski, QED, TPSA, Crippen LogP, 3D shape) with explicit choice tables, bit vs count semantics, and partial-charge model selection. Use when featurizing molecules for similarity, QSAR, virtual screening, or ML, or selecting the correct fingerprint for a chemotype-aware task.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
Performs retrosynthetic planning using AiZynthFinder (MCTS, template-based), Chemformer (template-free transformer), ASKCOS, and emerging RetroSynFormer with explicit handling of route scoring, building-block availability (eMolecules, Enamine, Mcule), forward prediction validation (Molecular Transformer), and disconnection-aware multi-objective search (MO-MCTS). Use when assessing synthetic feasibility of generated or selected molecules, planning multi-step syntheses, building synthesis-aware design pipelines, or screening libraries for retro-route feasibility.
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Fine-tune LLMs using reinforcement learning with TRL - SFT for instruction tuning, DPO for preference alignment, PPO/GRPO for reward optimization, and reward model training. Use when need RLHF, align model with preferences, or train from human feedback. Works with HuggingFace Transformers.
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