'prediction' 검색 결과

Analyzes differential transcript usage (DTU) and isoform switches with functional consequence prediction (NMD via 50nt rule, ORF disruption, protein domain loss/gain, signal peptide changes, IDR alterations, coding-potential shifts). Tools include IsoformSwitchAnalyzeR v2 (auto-selects satuRn for >5 reps else DEXSeq), the manual DRIMSeq -> DEXSeq/satuRn -> stageR DTU pipeline, and fishpond/swish for inferential-uncertainty-aware DTE. Distinguishes DTU from DGE and DTE; integrates external annotators (CPC2, Pfam, SignalP, IUPred2A or DeepTMHMM). Use when investigating how splicing differences alter protein function or trigger NMD-mediated degradation.

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Sequence-based deep learning for ATAC-seq using chromBPNet, BPNet, scBasset, or EnFormer. Use when correcting Tn5 bias with neural networks beyond k-mer models, predicting per-base accessibility profiles, scoring in silico variant effects at GWAS or rare-variant SNPs, discovering motifs via DeepLIFT/TF-MoDISco from a trained model, or generating cell-type-specific accessibility predictions for unobserved cell states.

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Predict enhancer-gene regulatory connections from ATAC-seq using ABC, ENCODE-rE2G, HiChIP, or Cicero. Use when linking distal enhancers to target genes, choosing between contact-aware (ABC, ENCODE-rE2G), accessibility-only (Cicero), and orthogonal (HiChIP H3K27ac, EpiMap) approaches, validating predictions against CRISPRi-FlowFISH gold-standard, or building cell-type-specific regulatory maps for fine-mapping or therapeutic target discovery.

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Expert causal reasoning and mental model construction for diagnosis and prediction in complex domains

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This skill should be used when the user wants to "test a claim against data", "validate an empirical hypothesis", "refine a model/theory with evidence", "characterize a pattern and verify it", "演繹と帰納で検証", "仮説をデータで検証して更新", "実例と反例で確かめる", "弁証法ループ", "主張を現物で裏取り", "傾向分析を検証して精緻化", or mentions iteratively updating a hypothesis by deriving predictions and testing them against a real corpus. NOTE: Use this for VALIDATING/REFINING an empirical claim or model against real data through a derive→test→update loop. Use strong-inference for debugging an UNKNOWN cause, and devils-advocate for adversarially stress-testing a DESIGN proposal.

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Workflow for fatigue and durability analysis - cycle counting, damage accumulation, and fatigue life prediction.

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基于历史数据利用统计分析方法预测下一组数字，严格遵守前5位(1-35)和后2位(1-12)的范围限制，输出简洁的预测结果。

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Query Polymarket: markets, prices, orderbooks, history.

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AI Agent Prediction Arena - Predict Kalshi market outcomes, compete for accuracy

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