'new' 검색 결과

Seed minimal agent harness v0 — manifest, eval checks stub, governance. AUTO-INVOKED after project-setup or retroactive-project-setup when docs/harness/manifest.json is missing. Also triggers on: generate harness, scaffold agents, agent bootstrap, first time agents in this repo, new project agent setup, set up agent harness, agent onboarding files, missing agent configuration, agent instructions setup, make agents read project rules, agent reliability setup, agents not configured. Pairs with project-setup. Evolution is harness-evolution.

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Turn a rough idea into a fully approved design before any code is written. Load when the user wants to brainstorm, explore ideas, design a feature, think through approaches, plan a new capability, or figure out what to build. Also triggers on "let's think through", "help me design", "explore options", "what's the best approach for", "I have an idea for", "before we build", or any request to design something before implementation. Enforces a hard gate: no code, no implementation until user approves a design. For executable feature specs (FRs, NFRs, ACs as Given/When/Then), route to `feature-spec` instead — brainstorming owns approach and architecture, not machine-readable requirements.

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Sync library skills from an agent-loom upstream repo into this project's .agents/skills while preserving project-local and forked skills. Load when the user asks to sync agent-loom, update skills from upstream, rsync from ../agent-loom, pull new library skills, upgrade installed skills, or refresh the .agents folder without losing custom project skills. Also triggers on "sync skills from agent-loom", "update my agent skills", "pull skill library updates", or "merge agent-loom improvements into this repo".

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Set up a new Prisma Postgres database and connect it to a local project using the Management API. Use when asked to "set up a database", "create a Prisma Postgres project", "get a connection string", "connect my app to Prisma Postgres", or "provision a database".

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Guides for configuring Prisma with different database providers (PostgreSQL, MySQL, SQLite, MongoDB, etc.). Use when setting up a new project, changing databases, or troubleshooting connection issues. Triggers on "configure postgres", "connect to mysql", "setup mongodb", "sqlite setup".

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Build and deploy applications when the user selects or invokes the Prisma plugin, including requests like "Build a simple Todo app and deploy it" that do not name a stack. Use Prisma Composer for new apps and Prisma Compute for deployment. Also use for explicit Composer/Compute requests, deployment diagnostics, and recovering Composer deployments. Does not cover unrelated ORM or database administration.

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Update an OpenSpec change by revising its existing planning artifacts and keeping them coherent with one another. Use when the user wants to revise a change's plan, fold new decisions into it, or reconcile its artifacts after an edit. Never edits code.

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Propose a new change with all artifacts generated in one step. Use when the user wants to quickly describe what they want to build and get a complete proposal with design, specs, and tasks ready for implementation.

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Automate customer engagement workflows including broadcast triggers, message analytics, segment management, and newsletter tracking through Customer.io via Composio

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Guide for creating effective skills. This skill should be used when users want to create a new skill (or update an existing skill) that extends Codex's capabilities with specialized knowledge, workflows, or tool integrations.

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Toolkit for styling artifacts with a theme. These artifacts can be slides, docs, reportings, HTML landing pages, etc. There are 10 pre-set themes with colors/fonts that you can apply to any artifact that has been creating, or can generate a new theme on-the-fly.

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A skill that creates new Claude skills and automatically shares them on Slack using Rube for seamless team collaboration and skill discovery.

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Analyzes your recent Codex chat history to identify coding patterns, development gaps, and areas for improvement, curates relevant learning resources from HackerNews, and automatically sends a personalized growth report to your Slack DMs.

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A set of resources to help me write all kinds of internal communications, using the formats that my company likes to use. Claude should use this skill whenever asked to write some sort of internal communications (status reports, leadership updates, 3P updates, company newsletters, FAQs, incident reports, project updates, etc.).

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This skill ensures all code follows security best practices and identifies potential vulnerabilities. Use when implementing authentication or authorization, handling user input or file uploads, or creating new API endpoints.

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Turn a one-line objective into a step-by-step construction plan any coding agent can execute cold. Each step has a self-contained context brief — a fresh agent in a new session can pick up any step without reading prior steps.

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⚠️ DEPRECATED: This SDK has been renamed to Call Automation. For new projects, use azure-communication-callautomation instead. This skill is for maintaining legacy code only.

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Predicts protein-coding gene structures (exons, introns, UTRs) in eukaryotic genomes with BRAKER3 (RNA-seq + protein evidence), BRAKER1/BRAKER2, GALBA (protein-only), Funannotate (fungi), GeMoMa (homology projection), or Helixer/Tiberius (deep-learning ab initio). Covers the evidence-first tool decision, mandatory soft-masking, the training-set-quality-dominates principle, OrthoDB clade-partition selection, the one-isoform-per-locus and missing-UTR traps, merge/split errors, and reference bias against orphan genes. Use when annotating a newly assembled eukaryotic genome, choosing a gene-prediction pipeline based on available evidence, or diagnosing a poor annotation.

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Annotates bacterial and archaeal genomes (isolates, MAGs, plasmids) with Bakta (active versioned databases, NCBI-compliant output) or Prokka (legacy), producing GFF3/GenBank/EMBL/FASTA with INSDC locus tags. Covers Bakta-vs-Prokka-vs-PGAP-vs-DFAST choice, light-vs-full database tiers, translation-table selection (11/4/25), archaeal and leaderless-gene caveats, the small-ORF blind spot, pseudogene-vs-phase-variation, the pangenome re-annotation trap, and submission compliance. Use when annotating a newly assembled prokaryotic genome, choosing an annotation tool, re-annotating a collection for pangenomics, or preparing annotations for NCBI/DDBJ submission.

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Transfers gene annotations between genome assemblies via coordinate liftover (UCSC liftOver, CrossMap for same-species version updates) or feature/sequence projection (Liftoff for same/close species, miniprot for protein-level cross-species, TOGA/GeMoMa/CAT for distant clades). Covers the coordinate-vs-projection decision by divergence, why a successful lift is not biological confirmation, reference bias, the silent-dropping of unmapped features, build/PAR/MHC/inversion hazards, and transfer-vs-de-novo validation. Use when annotating a new assembly of a species with an existing reference, harmonizing coordinates across builds, or mapping annotations across related species.

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Query UniProt's REST API (post-2022 endpoint at rest.uniprot.org) for protein sequences, annotations, GO terms, cross-references, ID mappings, and proteomes. Use when fetching UniProtKB entries, navigating the JSON schema, choosing between UniProtKB/UniRef/UniParc/Proteomes resources, deciding stream vs search endpoint for batch retrieval, running ID-mapping jobs with the async pattern, handling isoform suffixes, or filtering reviewed Swiss-Prot vs auto-annotated TrEMBL. Encodes the legacy URL migration (2022), the new JSON schema layout, and bulk-pull patterns.

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Computes and interprets treatment effect measures (OR, RR, RD, HR, NNT) with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen, MOVER, profile likelihood, Bender NNT) and reports marginal vs conditional estimands per FDA 2023 covariate adjustment guidance. Use when reporting treatment effects in confirmatory trials, comparing effect sizes across studies, or constructing forest plots.

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Trains and applies base-resolution deep learning models on ChIP-seq / ChIP-nexus / CUT&RUN data. Uses BPNet (Avsec 2021 Nat Genet 53:354; soft motif syntax from ChIP-nexus), chromBPNet (Pampari A et al 2025 Nat Genet; bias-factorized base-resolution profiles), EnFormer (Avsec 2021 Nat Methods 18:1196; 196 kb input, ~100 kb effective receptive field), DeepSEA (Zhou 2015; multi-task CNN), and JASPAR 2026 deep-learning collection (1259 BPNet ChIP models). Performs in silico mutagenesis for variant-effect prediction, DeepLIFT/Grad attribution, and TF-MoDISco motif discovery from attribution scores. Use when predicting variant effects on TF binding, discovering soft motif syntax / cooperativity, integrating ChIP-seq with sequence-only predictions, or applying precomputed JASPAR Deep Learning models to new variants.

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Designs novel molecules using REINVENT 4 (de novo, scaffold decoration, linker design, R-group, molecular optimization), MolMIM, Diffusion-based generators (DiGress, DiffSMol), and JT-VAE with explicit handling of multi-parameter optimization (MPO), goal-directed scoring functions, transfer/reinforcement/curriculum learning, synthetic accessibility scoring, and chemical space exploration vs exploitation. Use when designing new chemical matter against a target, decorating a scaffold, linking fragments, or optimizing a hit for multiple ADMET / activity properties simultaneously.

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