'quant' 검색 결과

Process mass spectrometry data using scripts for format conversion, signal cleanup, peak detection, and quantification across samples. Prepare protein and metabolite analyses with identification filtering, candidate annotations, data tables, and plots.

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• Inspect, convert, and preprocess mass spectrometry files
• Build quantitative tables across multiple samples
• Find metabolite candidates from accurate mass

Prepare bulk RNA-seq sequencing files or quantification outputs for gene-level comparisons. Check sample information and data quality, configure processing workflows, and assemble validated count tables and metadata for downstream differential expression analysis with PyDESeq2.

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• Preparing gene count tables from FASTQ files
• Configuring an nf-core/rnaseq workflow
• Combining Salmon, STAR, or featureCounts outputs

Develop AxonX plugins and manage quantitative finance research through the command line or MCP, an agent connection interface. Track data preparation, training, prediction, and historical strategy tests using execution status, logs, artifacts, and dependencies.

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• Develop research plugins with defined inputs and outputs
• Run data preparation, training, prediction, and backtests
• Investigate failed tasks through status and logs

Check a wallet’s token holdings on a selected blockchain, with token names, symbols, current prices, 24-hour price changes, and quantities. Supports BSC, Solana, Base, and Ethereum for reviewing the wallet’s current portfolio.

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• Reviewing the tokens held in a wallet
• Checking current prices and 24-hour changes for held tokens
• Checking token quantities on a selected blockchain

Export an approved fine-tuned model into a format suited to its hardware and runtime. Choose weight packaging and quantization, which reduces numerical precision, then compare outputs before and after export to check for regressions.

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• Exporting a checkpoint approved for deployment
• Choosing a model format for a target GPU or laptop
• Comparing outputs before and after export

Apply statistical tests to financial time series, model changing volatility, and diagnose regression problems. Estimate uncertainty in strategy metrics through bootstrap resampling, which repeatedly samples existing data, and organize findings into a statistical testing report.

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• Check whether price and return series are statistically stable
• Test long-term relationships between two assets
• Diagnose regression problems in factor research

Run language models locally with llama.cpp on CPUs, Apple Silicon, or AMD and Intel GPUs. The skill guides model setup, memory-saving GGUF format choices, interactive chat, and serving models through an OpenAI-compatible API.

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• Running a language model on a CPU-only computer
• Setting up local chat on an Apple Silicon Mac
• Choosing model quantization to fit available memory

Configure LLM inference and serving on NVIDIA GPUs with TensorRT-LLM. Covers quantization, which reduces numerical precision, batching requests during generation, and distributing models across GPUs to improve processing capacity and response times.

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• Setting up an LLM server on NVIDIA GPUs
• Configuring FP8 or INT4 quantization
• Distributing large models across multiple GPUs

Reduce GPU memory use by loading language models in 8-bit or 4-bit formats with bitsandbytes and HuggingFace Transformers. Includes configuration examples, QLoRA fine-tuning of compressed models, and optimizers that reduce memory needed during training.

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• Load larger models within limited GPU memory
• Compare 8-bit and 4-bit model settings
• Fine-tune a model with QLoRA

Deploy language model APIs and run batch generation with vLLM. Configure GPU memory use, quantization—lower precision model storage—and distribution across GPUs, then test response times and monitor how many requests the server handles.

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• Deploying an OpenAI-compatible language model API
• Generating responses for a large set of prompts
• Fitting a large model into limited GPU memory

Configure LLM inference and serving on NVIDIA GPUs with TensorRT-LLM. Covers quantization, which reduces numerical precision, batching requests during generation, and distributing models across GPUs to improve processing capacity and response times.

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• Setting up an LLM server on NVIDIA GPUs
• Configuring FP8 or INT4 quantization
• Distributing large models across multiple GPUs

Guides you through running large language models on CPUs, Apple Silicon, and AMD or Intel GPUs. Covers choosing GGUF model files, reducing memory through quantization, and starting an OpenAI-compatible chat server.

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• Running a local LLM on an Apple Silicon Mac
• Trying LLM inference on a CPU-only machine
• Choosing a model format that fits available memory

Compress large language models to 4-bit weights to reduce GPU memory needs and accelerate text generation. Covers loading compressed models, converting your own models, choosing settings, and preparing memory-efficient fine-tuning with transformers and PEFT.

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• Run language models with limited GPU memory
• Convert your own model to 4-bit weights
• Compare compression settings for quality and speed

Find and run local AI models with llama.cpp. Choose GGUF model files and quantization levels that fit available memory, launch a command line session or local server, and test an OpenAI-compatible API on your computer.

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• Find models to run on a local computer
• Choose quantization for available memory
• Launch and test a local OpenAI-compatible API

Design studies that combine quantitative data, such as surveys, with qualitative evidence, such as interviews. It recommends a suitable design and outlines study phases, participant selection, timing, and ways to combine findings into an integrated interpretation.

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• Plan follow-up interviews to explain survey results
• Develop survey measures from interview findings
• Compare quantitative and qualitative findings

Port quantum circuits from Qiskit or other frameworks into CUDA-Q while preserving the original algorithm. Guides gate conversion, measurement ordering, precision checks, and small test comparisons to produce code that runs without the source framework.

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• Porting Qiskit circuits to CUDA-Q
• Comparing measurement results after migration
• Removing source framework dependencies

Detect and quantify translated ORFs from Ribo-seq data including uORFs and novel ORFs using RiboCode and ORFquant. Use when identifying translated regions beyond annotated coding sequences or quantifying ORF-level translation.

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Discovers, classifies, filters, and quantifies full-length transcript isoforms from PacBio Iso-Seq/Kinnex (HiFi) and Oxford Nanopore (cDNA/direct-RNA) long reads, using the isoseq+pigeon pipeline, SQANTI3, and ONT tools (IsoQuant, FLAIR, Bambu, StringTie2). Covers why a novel isoform is an artifact until proven otherwise (RT template-switching, intra-priming, and 5' degradation manufacture junctions and truncations), the SQANTI3 structural categories and their trust order, the Kinnex skera-split step, orthogonal CAGE/poly-A/short-read-junction validation, and why long-read isoform quantification needs EM. Use when building a full-length isoform catalog, classifying/filtering long-read transcripts, running Iso-Seq or ONT cDNA/dRNA analysis, or judging novel-isoform reliability.

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Quantifies CRISPR editing outcomes with CRISPResso2 (Clement 2019 Nat Biotechnol) across Cas9-nuclease (indels, HDR), CBE and ABE base editors (target conversion + bystander), and prime editor (pegRNA-templated) modes. Covers single-amplicon (CRISPResso), multi-sample batch (CRISPRessoBatch), pooled-amplicon (CRISPRessoPooled), WGS off-target (CRISPRessoWGS), and sample-comparison (CRISPRessoCompare) workflows; quantification-window math that controls what is called edited; substitution-vs-indel diagnostic to distinguish BE from Cas9 contamination; MMEJ deletion pattern interpretation; allele-frequency tables; and failure modes from amplicon misalignment or contamination. Use when quantifying editing from amplicon sequencing, choosing CRISPResso mode by design, distinguishing intended edits from bystanders and indel byproducts, debugging low-alignment runs, or generating publication-grade editing reports.

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MaxQuant + Perseus proteomics pipeline: run MaxQuant for LFQ and SILAC; parse proteinGroups.txt in Python; filter contaminants/decoys; log2 + median-normalize; impute MNAR; t-test with FDR; volcano plot; GO/pathway enrichment. Use Proteome Discoverer for Thermo-native processing; FragPipe/MSFragger for GPU-accelerated DB search.

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Match BIM quantities to CWICR work items. Map element categories to cost codes, validate quantities, and generate cost-linked QTOs.

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Use bitsandbytes for k-bit PyTorch quantization, Hugging Face quantized model loading, 8-bit and paged optimizers, direct quantized layers/functions, and backend installation diagnostics.

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Guides privacy impact assessment for emerging technologies including IoT, blockchain, AR/VR, quantum computing, and digital twins. Covers risk identification methodology, proportionality assessment, and technology-specific privacy challenges. Activate when evaluating new technology adoption, innovation projects, or emerging tech procurement. Keywords: PIA, emerging technology, IoT, blockchain, AR/VR, quantum computing, digital twins, innovation privacy.

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Quantifies CRISPR editing outcomes with CRISPResso2 (Clement 2019 Nat Biotechnol) across Cas9-nuclease (indels, HDR), CBE and ABE base editors (target conversion + bystander), and prime editor (pegRNA-templated) modes. Covers single-amplicon (CRISPResso), multi-sample batch (CRISPRessoBatch), pooled-amplicon (CRISPRessoPooled), WGS off-target (CRISPRessoWGS), and sample-comparison (CRISPRessoCompare) workflows; quantification-window math that controls what is called edited; substitution-vs-indel diagnostic to distinguish BE from Cas9 contamination; MMEJ deletion pattern interpretation; allele-frequency tables; and failure modes from amplicon misalignment or contamination. Use when quantifying editing from amplicon sequencing, choosing CRISPResso mode by design, distinguishing intended edits from bystanders and indel byproducts, debugging low-alignment runs, or generating publication-grade editing reports.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.