'dma' 검색 결과

Estimates SNP heritability and partitions it across functional annotations, cell types, and loci from GWAS summary statistics or individual-level genotypes. Implements LDSC, stratified LDSC with the baseline-LD model, Finucane 2018 cell-type prioritization, LDAK SumHer, HDL, HESS local heritability, BOLT-REML, GCTA-GREML, graphREML, and Popcorn cross-population genetic correlation. Use when computing total h2_SNP from summary stats, partitioning heritability across functional categories, prioritizing trait-relevant tissues or cell types from ENCODE/Roadmap chromatin marks, reconciling LDSC vs LDAK enrichment estimates, computing local heritability with HESS, estimating genetic correlation between traits, or producing publication-grade enrichment with calibrated sensitivity to model assumptions.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Align protein structures using Foldseek 3Di, TM-align, US-align, DALI, or Foldmason for structural MSA. Predict, score, and superpose backbone coordinates when sequence identity is below the twilight zone or remote-homology detection is required. Use when sequence MSA fails (<25% identity), when the dark proteome is the target, when AlphaFoldDB / ESM Atlas search is needed, or when structural superposition is the goal.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Local-only regression / benchmark skill for ui-clone-skills maintainers. Drives the standard ui-reverse-engineering pipeline against the canonical reference site (https://realfood.gov) and records AE/SSIM, iteration count, gate fail counts, and outcome to benchmark/history.csv so prompt / sub-doc / model-version drift surfaces as a trend. Trigger phrases: "run benchmark" / "regression benchmark" / "benchmark clone". The Makefile no longer has a `benchmark` target — setup is inline bash in this skill (Step 1 below). Internal: NOT registered in `.claude-plugin/plugin.json` `skills`. Not part of the public 3-skill marketplace surface. Maintainer tooling only.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Capture baseline evidence from a live website URL: screenshots, scroll states, hover/click behavior, parallax, timers, and transition recordings. Use when reference artifacts are needed before implementation or comparison; not to build or diagnose a clone.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Clone or recreate a live website URL, page, or section as React + Tailwind with extracted DOM, CSS, assets, responsive layout, motion, and interactions. Use for live-URL implementation or fidelity repair; not capture-only or diff-only requests.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Diagnose why an existing implementation differs from reference evidence using AE/SSIM, pixel, section, computed-style, and transition diffs. Use for post-implementation mismatch or repair guidance; not baseline capture or full clone generation.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

This skill suggests treatment with either a calcimimetic or an intravenous bisphosphonate/denosumab for hypercalcemia due to parathyroid carcinoma. Triggered when a clinician diagnoses parathyroid carcinoma-associated hypercalcemia of malignancy and inquires about initial medical management options.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

The skill suggests adding a calcimimetic for hypercalcemia of malignancy due to parathyroid carcinoma that persists after intravenous bisphosphonate or denosumab therapy. It is triggered when a clinician notes refractory HCM despite antiresorptive therapy and considers adding a calcimimetic.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

This skill suggests using denosumab rather than an intravenous bisphosphonate for adults with hypercalcemia of malignancy. It is triggered when a clinician questions which antiresorptive to choose first or seeks guidance on drug selection for HCM.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Recommends initiating intravenous bisphosphonate or denosumab for adults with hypercalcemia of malignancy compared with no treatment. Use when a clinician asks about first‑line pharmacologic therapy for HCM or when deciding to start antiresorptive agents.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Recommends adding intravenous bisphosphonate or denosumab when hypercalcemia due to parathyroid carcinoma is not adequately controlled with a calcimimetic. Consider this adjunct when a clinician notes persistent HCM despite calcimimetic therapy and asks about next-step therapy.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Recommends combination of calcitonin and an intravenous bisphosphonate or denosumab as initial treatment for severe hypercalcemia (serum calcium >14 mg/dL). Indicated when a clinician notes severe HCM or seeks rapid calcium lowering in symptomatic patients.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Recommends adding intravenous bisphosphonate or denosumab in adults with hypercalcemia of malignancy due to tumors with high calcitriol levels (e.g., lymphoma) who remain severe or symptomatic despite glucocorticoid therapy. Use when managing lymphoma‑related HCM on steroids and considering escalation of antiresorptive therapy.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Recommends denosumab for adults with refractory or recurrent hypercalcemia of malignancy who have persistent or relapsed hypercalcemia despite intravenous bisphosphonate therapy. Triggered when a clinician observes recurrent hypercalcemia after bisphosphonate treatment or considers next‑line agents for HCM.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Read-only release + backlog recap. Reports the last release, commits-since-tag classified by conventional-commit type with the semver bump they trigger and pushed-vs-origin state, the backlog bucketed (open/picked-up/dropped with epic parent→child nesting), the roadmap epics with their per-task tallies, and condensed open questions — then recommends the next pickup. One `cli.mjs recap` call returns all six recap keys. Invoke any time (on demand) to plan a release or choose the next thing to build; a compact form is also surfaced at session start. Not a workflow phase; never writes CHANGELOG; never starts or commits work.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Review the auto-extracted candidates in `.claude/memory/_pending.md` and commit keepers to the canonical memory files (`landmarks.md`, `libraries.md`, `decisions.md`, `landmines.md`, `conventions.md`, `pending-questions.md`, `backlog.md`). Invoke at session start when the SessionStart hook reports pending candidates, or any time `_pending.md` has accumulated entries you want to curate. Reset the pending body after flushing.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

A workflow skill that lets Codex keep coding for 60 hours on medium and large projects: Claude Code CLI plans through an interactive requirements questionnaire, PRD, specs, and roadmap; Codex implements verified vertical slices, with resumable Long-Run Execution for lengthy work; Trellis maintains project memory. Use when the user mentions 大项目工作流, Codex 连续开发 60 小时, Codex 长任务, long-running or resumable Codex implementation, large/medium project, new SaaS, multi-module system, requirements questionnaire, Claude Code CLI planning, Codex implementation handoff, Trellis bootstrap, non-system-drive project, or vertical slice. Skip for: single-file edits, casual Q&A, copy polish, throwaway prototypes, or tasks the user explicitly wants done fast without process.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Auri: assistente de voz inteligente (Alexa + Claude claude-opus-4-20250805). Visao do produto, persona Vitoria Neural, stack AWS, modelo Free/Pro/Business/Enterprise, roadmap 4 fases, GTM, north star WAC e analise competitiva.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Maintain vision, user journeys, evolving requirements and roadmap outcomes when intent or acceptance changes.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Decompose an epic into atomic parallelizable tasks, route each to the right skill, and keep the four delivery records straight — issues, STATUS, ROADMAP, CHANGELOG. Use as a meta-router when several skills could apply, and as the baseline for how delivery state is recorded. Trigger at the start of any multi-track epic, when the skill count exceeds ~12, or when the records have drifted from reality.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Pursue an agreed goal to a working outcome without waiting: decompose it, re-prioritise as evidence arrives, branch, gate, get an independent review (a different model or a fresh reviewer subagent — the writer never approves), merge, prune, and bank the operator's decisions in STATUS.md instead of blocking on them. Trigger on "get it done", "don't wait for me", "proceed autonomously", or when an epic or roadmap objective is handed over. Not a close-out: this work set is expected to grow.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Turns a vague "what should we do about X" into a scored decision - explicit actions, an explicit unknown, an explicit prior, and one utility scale - then picks by maximum expected utility and checks the result for framing effects. Use when facing a choice between options under uncertainty, when a decision has stalled in circular debate, when someone asks "should we do A or B", or before writing any decision record, strategy memo, or roadmap commitment.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Decides how far ahead to plan, what to discount future payoffs by, and which backlog items can be dropped without analysis - using receding-horizon planning, an explicit discount factor, and branch-and-bound pruning against the incumbent. Use when building a roadmap, prioritising a backlog, arguing about short-term versus long-term, setting quarterly or annual plans, or when planning has become an end in itself.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Shape or update a rolling-wave engineering project before slice preparation. Use when the user wants to start a rolling-wave project, define the finish line, clarify success criteria, create or update docs/rolling-wave/{project}/project.md, sketch a broad roadmap, or interrogate project-level direction without implementation details.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.