'principles' 검색 결과

Next.js App Router principles. Server Components, data fetching, routing patterns.

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Database design principles and decision-making. Schema design, indexing strategy, ORM selection, serverless databases.

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Production deployment principles and decision-making. Safe deployment workflows, rollback strategies, and verification. Teaches thinking, not scripts.

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API design principles and decision-making. REST vs GraphQL vs tRPC selection, response formats, versioning, pagination.

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Build production-grade Azure Cosmos DB NoSQL services following clean code, security best practices, and TDD principles.

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API design principles and decision-making. REST vs GraphQL vs tRPC selection, response formats, versioning, pagination.

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bu skill guides organizations through implementing zero trust architecture in cloud environments following NIST SP 800-207 and Google BeyondCorp principles. It covers identity-centric access controls, micro-segmentation, continuous verification, device trust assessment, and Dağıt:ing Identity-Aware Proxy to eliminate implicit network trust in AWS, Azure, and GCP environments.

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Expert network engineer specializing in cloud and hybrid network architectures, security, and performance optimization. Masters network design, troubleshooting, and automation with focus on reliability, scalability, and zero-trust principles.

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Accessibility testing toolkit using Selenium WebDriver 4+ with Java 21+ and axe-core engine. Use when asked to validate WCAG 2.1/2.2 compliance, scan pages or components for a11y violations, test keyboard navigation, audit color contrast, check ARIA semantics, generate accessibility reports, filter axe rules, debug screen reader issues, or implement POUR principles (perceivable, operable, understandable, robust).

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Plan accessibility compliance - WCAG 2.2, Section 508, EN 301 549, inclusive design principles, audit planning, and remediation strategies.

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Write clear, testable acceptance criteria in Given-When-Then format following INVEST principles and BDD best practices.

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Accessibility testing for web applications using Playwright (@playwright/test) with TypeScript and axe-core. Use when asked to write, run, or debug automated accessibility checks, keyboard navigation tests, focus management, ARIA/semantic validations, screen reader compatibility, or WCAG 2.1 Level AA compliance testing. Covers axe-core integration, POUR principles (perceivable, operable, understandable, robust), color contrast, form labels, landmarks, and accessible names.

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Scaffolds a complete .NET solution following Clean Architecture principles with proper layer separation (API, Application, Domain, Infrastructure). Creates project structure, dependency injection setup, and cross-cutting concerns configuration.

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Technical research methodology with YAGNI/KISS/DRY principles. Phases: scope definition, information gathering, analysis, synthesis, recommendation. Capabilities: technology evaluation, architecture analysis, best practices research, trade-off assessment, solution design. Actions: research, analyze, evaluate, compare, recommend technical solutions. Keywords: research, technology evaluation, best practices, architecture analysis, trade-offs, scalability, security, maintainability, YAGNI, KISS, DRY, technical analysis, solution design, competitive analysis, feasibility study. Use when: researching technologies, evaluating architectures, analyzing best practices, comparing solutions, assessing technical trade-offs, planning scalable/secure systems.

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Build project-level design systems based on Material Design principles. Use when creating a new design system, extracting one from an existing product, extending tokens or components, or reviewing UI for design system compliance. Outputs a project-level Agent Skill with token definitions and component specifications.

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Manages project versioning following Semantic Versioning (SemVer) principles. Calculates increments based on changes and synchronizes version across documentation and metadata. Use when the user asks to "bump the version", "prepare a release", or when the `changelog` skill calls for a release.

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Reference for writing and editing skills well — the vocabulary and principles that make a skill predictable.

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Solve quantitative problems in biophysics — pharmacokinetics (PK volume of distribution, clearance, half-life), epidemiology (R0, attack rate), toxicology (LD50, NOAEL), population genetics (Hardy-Weinberg, Fst), enzyme kinetics (Michaelis-Menten), thermodynamics. Use for first-principles quantitative biology calculations, dose calculations, exposure assessment, and biophysical-property estimation.

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Strategic clinical trial design feasibility assessment. Analyzes 6 dimensions (endpoint, population, comparator, effect size, duration, regulatory pathway) using precedent trials and FDA guidance. Produces enrollment projections, endpoint recommendations, and approval-pathway analysis. Use for trial-protocol design, power/sample-size estimation, comparator selection, and FDA submission strategy. Driven by precedent-based reasoning rather than first-principles math.

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Structures biological experiments so inference is valid by construction, covering Fisher's principles (randomization, replication, local control), the experimental-vs-observational unit distinction and pseudoreplication (Hurlbert 1984; Lazic 2018), randomization mechanics (complete, restricted, stratified, rerandomization, run-order), blocking layouts (randomized complete block, Latin square, incomplete block), factorial designs and interactions, and the split-plot/nested error strata hidden inside multi-batch genomics. Use when deciding the experimental unit and what counts as a replicate, planning randomization and run order, choosing a blocked/factorial/split-plot/nested layout, avoiding pseudoreplication in cell-culture or animal studies, or specifying the random-effects structure of the analysis model. For assigning samples to sequencing batches/lanes/plates and batch-effect correction see experimental-design/batch-design; for regulated clinical-trial randomization see clinical-biostatistics.

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Organic chemistry reasoning guide for reaction product prediction, mechanism analysis (electrophilic/nucleophilic substitution, addition, elimination, pericyclic, radical), and spectroscopy interpretation (1H/13C NMR, IR, MS). Reasons from first principles (electron flow, kinetic vs thermodynamic) rather than pattern-matching named reactions. Use for organic synthesis problems and mechanism explanations.

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Predicts ADMET properties using ADMETlab 3.0 (119 endpoints with uncertainty), ADMET-AI, DeepChem MolNet, and chemprop D-MPNN with explicit handling of OECD QSAR principles, applicability domain assessment, calibration, hERG/CYP/AMES gold-standard endpoints, and PAINS / Lipinski / Ro5 / Veber / BBB druglikeness filters. Use when filtering compounds for drug-likeness, prioritizing leads by predicted safety, or building an in-house ADMET QSAR model.

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Builds QSAR / QSPR models using chemprop D-MPNN, MolFormer, Uni-Mol, ChemBERTa, random forest baselines, and Gaussian processes with explicit handling of OECD 5 principles, applicability domain (kNN, leverage, conformal prediction, Mahalanobis), scaffold-balanced splits, ensemble uncertainty, calibration (Platt, isotonic), feature importance (SHAP, atomic attribution), and prospective validation. Use when building target-specific predictive models from in-house bioassay data, ADMET endpoints, or selectivity profiles.

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Push the LLM to reconsider, refine, and improve its recent output. Use when user asks for deeper critique or mentions a known deeper critique method, e.g. socratic, first principles, pre-mortem, red team.

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