779건 · 관련도순
Configure deployment settings for /land-and-deploy. Detects your deploy platform (Fly.io, Render, Vercel, Netlify, Heroku, GitHub Actions, custom), production URL, health check endpoints, and deploy status commands. Writes the configuration to CLAUDE.md so all future deploys are automatic. Use when: "setup deploy", "configure deployment", "set up land-and-deploy", "how do I deploy with gstack", "add deploy config".
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Design stable APIs and module boundaries — contract-first types, consistent errors, boundary validation, additive changes. Load when designing REST or GraphQL endpoints, public module interfaces, component props, or FE/BE contracts. Also triggers on "API design", "interface design", "design the API", "module boundary", "API contract", "define the interface". Complements feature-spec (product layer). Routes breaking retirement to api-deprecation-and-migration when it exists.
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This skill ensures all code follows security best practices and identifies potential vulnerabilities. Use when implementing authentication or authorization, handling user input or file uploads, or creating new API endpoints.
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Azure Monitor Ingestion SDK for Java. Send custom logs to Azure Monitor via Data Collection Rules (DCR) and Data Collection Endpoints (DCE).
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Builds production-ready REST API endpoints with validation, error handling, authentication, and documentation. Follows best practices for security and scalability.
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Generate comprehensive, developer-friendly API documentation from code, including endpoints, parameters, examples, and best practices
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Controls error rates across thousands of simultaneous tests in genomics discovery using false-discovery-rate methods (Benjamini-Hochberg 1995; Benjamini-Yekutieli 2001 for arbitrary dependence; Storey q-value with pi0 estimation; local FDR; independent filtering Bourgon 2010; covariate-weighted FDR via IHW Ignatiadis 2016), plus family-wise error control (Bonferroni, Holm) and the GWAS genome-wide threshold. Covers the FDR-versus-FWER choice as the discovery-versus-confirmatory distinction, the dependence assumptions behind BH (PRDS) versus BY, pi0 estimation, the independent-filtering and false-coverage-rate traps, and reproducibility ranking via IDR (Li 2011). Use when correcting p-values from genome-wide tests, choosing between BH/BY/q-value/Bonferroni, setting an FDR threshold, applying IHW or independent filtering, or interpreting q-values. For confirmatory trials with few pre-specified endpoints (closed testing, graphical/gatekeeping), see clinical-biostatistics/multiplicity-graphical.
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Maps between gene identifier systems (Ensembl, Entrez, HGNC symbol, UniProt, RefSeq, MANE) using AnnotationDbi, biomaRt, mygene, pyensembl, and Ensembl REST. Encodes Ensembl version stripping with GENCODE _PAR_Y preservation, the Ziemann 2016 Excel autocorrect debacle and Bruford 2020 HGNC renames (SEPT*->SEPTIN*, MARCH*->MARCHF*, MARC*->MTARC*, DEC1->DELEC1), OCT4/POU5F1 alias resolution, biomaRt archive endpoints for release pinning, the `filters` (plural) gotcha, MANE Select for clinical reporting, cross-species orthology via Ensembl Compara / OMA / OrthoDB, and tx2gene construction for tximport. Use when converting gene IDs across systems, handling renamed symbols, building tx2gene, pinning to a specific Ensembl release for reproducibility, or mapping cross-species orthologs.
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Query the Ensembl REST API for gene/transcript/protein lookup, sequence retrieval, comparative genomics (Compara), variant effect prediction (VEP), regulatory features, and cross-species ortholog/paralog calls. Use when pulling Ensembl-native data (Ensembl Gene IDs, version-pinned releases, archive endpoints for reproducibility), gene/transcript/exon structure with stable IDs, or VEP for variant annotation. Encodes the 15 req/sec rate limit, archive (e110.rest.ensembl.org) for reproducibility, Ensembl divisions (vertebrates / plants / fungi / metazoa / bacteria), and the symbol-vs-ID stability problem.
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Computes sample size and power for clinical trials including continuous, binary, and time-to-event endpoints; superiority, non-inferiority, and equivalence designs; FDA 2016 non-inferiority margin selection with M1/M2 framework; Schoenfeld 1981 and Lakatos 1988 for survival; Schuirmann TOST and 80-125% bioequivalence; minimum clinically important difference (MCID) vs δ distinction. Use when justifying trial size in protocol or SAP per CONSORT 2025 item 7.
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Performs time-to-event analysis for clinical trials including Cox proportional hazards regression with PH diagnostics, restricted mean survival time (RMST) under non-PH, competing risks via Fine-Gray vs cause-specific Cox, weighted log-rank and MaxCombo for non-proportional hazards, recurrent events (Andersen-Gill, PWP, WLW), and interval-censored data. Use when analyzing time-to-event endpoints (OS, PFS, DOR, TTR, TTNT) in oncology or other clinical trials.
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Tests associations between categorical variables in clinical data using chi-square, Fisher's exact, Boschloo, Cochran-Mantel-Haenszel, and modern McNemar variants with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen). Use when analyzing categorical outcomes, paired binary endpoints, or testing treatment-outcome independence in confirmatory or exploratory clinical trials.
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Performs logistic regression for clinical trial outcomes (binary, ordinal, multinomial) with marginal-vs-conditional estimand reporting per FDA 2023 covariate adjustment guidance, g-computation/standardisation for marginal effects, modified Poisson for RR, Brant test for proportional odds, Firth penalty for separation, and Hauck-Donner detection. Use when modeling binary or ordinal endpoints in confirmatory or exploratory clinical trials.
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Builds QSAR / QSPR models using chemprop D-MPNN, MolFormer, Uni-Mol, ChemBERTa, random forest baselines, and Gaussian processes with explicit handling of OECD 5 principles, applicability domain (kNN, leverage, conformal prediction, Mahalanobis), scaffold-balanced splits, ensemble uncertainty, calibration (Platt, isotonic), feature importance (SHAP, atomic attribution), and prospective validation. Use when building target-specific predictive models from in-house bioassay data, ADMET endpoints, or selectivity profiles.
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Generates OpenAPI 3.0/3.1 specs, TypeScript client types, and curl examples from existing route handler code. Supports Express, Next.js API routes, Fastify, and Hono. Produces complete documentation including auth requirements, rate limits, error codes, and request/response examples. Activate on: 'generate API docs', 'OpenAPI from code', 'document endpoints', 'API reference', 'swagger generation', 'endpoint documentation'. NOT for: API design from scratch (use api-architect), deployment (use devops-automator), testing (use test-automation-expert).
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Convex backend specialist. Use this agent for any code inside a `convex/` directory — function definitions, schemas, indexes, queries, mutations, actions, HTTP endpoints, cron jobs, file storage, auth wiring, and component installation. Knows the object-form function syntax, validator patterns, resource limits, and component ecosystem that generic Claude routinely gets wrong.
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Create Convex queries, mutations, and actions with proper validation, authentication, and error handling. Use when implementing new API endpoints.
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Implement REST APIs in ABP Framework with AppServices, DTOs, pagination, filtering, and authorization. Use when building API endpoints for ABP applications.
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Agent-to-Agent (A2A) server configuration patterns for HTTP, STDIO, SSE, and WebSocket transports. Use when building A2A servers, configuring MCP transports, setting up server endpoints, or when user mentions A2A configuration, server transport, MCP server setup, or agent communication protocols.
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Use this skill when adding authentication, handling user input, working with secrets, creating API endpoints, or implementing payment/sensitive features. Provides comprehensive security checklist and patterns.
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Azure Monitor Ingestion SDK for Java. Send custom logs to Azure Monitor via Data Collection Rules (DCR) and Data Collection Endpoints (DCE).
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Generate comprehensive, developer-friendly API documentation from code, including endpoints, parameters, examples, and best practices
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Builds production-ready REST API endpoints with validation, error handling, authentication, and documentation. Follows best practices for security and scalability.
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Expert in integrating third-party APIs with proper authentication, error handling, rate limiting, and retry logic. Use when integrating REST APIs, GraphQL endpoints, webhooks, or external services. Specializes in OAuth flows, API key management, request/response transformation, and building robust API clients.
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