Analyze ad creatives (images and videos) extracted from competitor research. Use when given a directory of ad images, video files, or transcripts to evaluate ad quality, score visual and messaging effectiveness, assign a scale score for viral/engagement potential, and generate a cross-creative pattern summary. Triggered by requests like "analyze these ads", "score these creatives", "what hooks are competitors using", "evaluate the ad library", "give me a scale score", "analyze the ad folder", or "what's working in these ads".
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modbender/skill-library-mcp☆ 172026년 9월 28일 업데이트
Transcribe audio to timestamped lyrics using OpenAI Whisper or ElevenLabs Scribe API. Outputs LRC, SRT, or JSON with word-level timestamps. Use when users want to transcribe songs, generate LRC files, or extract lyrics with timestamps from audio.
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modbender/skill-library-mcp☆ 172026년 9월 28일 업데이트
Structured memory system for OpenClaw agents. Context death resilience (checkpoint/recover), structured storage, Obsidian-compatible markdown, local semantic search, and session transcript repair.
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modbender/skill-library-mcp☆ 172026년 9월 28일 업데이트
Transform learning content (like YouTube transcripts, articles, tutorials) into actionable implementation plans using the Ship-Learn-Next framework. Use when user wants to turn advice, lessons, or educational content into concrete action steps, reps, or a learning quest.
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manu14357/zskills☆ 162026년 7월 24일 업데이트
Analyze meeting transcripts to identify communication patterns, behavioral insights, and actionable feedback for improving communication and leadership effectiveness.
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manu14357/zskills☆ 162026년 7월 24일 업데이트
Calculates statistical power for high-dimensional genomics experiments (bulk RNA-seq, scRNA-seq, ATAC-seq, ChIP-seq, methylation, proteomics) under negative-binomial count models using RNASeqPower, PROPER, and simulation via powsimR, distinguishing per-gene from marginal (transcriptome-wide) power, the role of mean expression and dispersion, and the sequencing-depth-versus-replicate tradeoff. Covers simulation as the honest default for overdispersed counts, FDR-aware average power versus single-test power, observed/post-hoc power as an anti-pattern, and the winner's-curse / Type-S / Type-M consequences of underpowering. Use when planning replicate number for a sequencing experiment, deciding whether to add depth or samples, choosing closed-form versus simulation power, estimating power from pilot dispersions, or justifying replication in a grant. For clinical-trial power see clinical-biostatistics/power-and-sample-size; for the inverse sample-size question see experimental-design/sample-size.
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lilinji/GeneTind-Life-Skills☆ 152026년 8월 21일 업데이트
Infer transcription factor regulons from single-cell RNA-seq with pySCENIC by combining GRNBoost2 co-expression, cisTarget motif-enrichment pruning, and AUCell per-cell activity scoring. Covers the motif-pruning-as-directionality principle, regulon specificity scoring, run-to-run stability, and database/species matching. Use when identifying TF regulons, scoring TF activity per cell, finding master regulators of cell identity, or comparing regulon activity across conditions. For enhancer-driven multiomic GRNs see multiomics-grn; for bulk inference and VIPER protein-activity see grn-inference.
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lilinji/GeneTind-Life-Skills☆ 152026년 8월 21일 업데이트
Identifies differential m6A methylation between conditions from MeRIP-seq paired IP/input data using exomePeak2 (GC-bias-aware differential via its bam_ip/bam_input control + bam_treated_ip/bam_treated_input treatment arms), QNB beta-binomial, MeTDiff HMM, and RADAR, plus the paired-symmetric edgeR/DESeq2-on-peak-counts route when batch/lot covariates need fixed-effect handling that exomePeak2's API does not accept. Covers paired vs unpaired vs interaction designs, batch confounding and per-lot meta-analysis, the stoichiometry-vs-expression-vs-IP-efficiency confound, and effect-size filtering against under-powered N=2 designs. Use when comparing m6A across two or more conditions, choosing between exomePeak2/QNB/RADAR/MeTDiff for a design, handling batch confounding when exomePeak2's API is too rigid, distinguishing real hyper/hypo-methylation from expression shifts, applying effect-size thresholds, or planning orthogonal stoichiometry validation (GLORI/SAC-seq/m6Anet mod_ratio).
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lilinji/GeneTind-Life-Skills☆ 152026년 8월 21일 업데이트
Imports gene expression count matrices from featureCounts, HTSeq, STAR ReadsPerGene, Salmon/kallisto via tximport or tximeta, RSEM, 10X Genomics MTX/H5, AnnData H5AD, and RDS. Handles silent-miscounting traps (featureCounts -p v2.0.2 API break, STAR strandedness column choice, salmon NumReads-sum without tximport, RSEM non-integer expected_count, GENCODE _PAR_Y suffix, zero-length-transcript TPM divide-by-zero), and encodes the tximport countsFromAbundance decision tree with the "lengthScaledTPM is not TPM" warning. Use when assembling a gene-by-sample count matrix from aligner or quantifier output, importing salmon/kallisto for DESeq2 vs limma-voom, choosing strandedness column for STAR, debugging zero-count panics, or building tx2gene mapping.
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lilinji/GeneTind-Life-Skills☆ 152026년 8월 21일 업데이트
Infer gene regulatory networks from bulk or general expression data with mutual-information (ARACNe) and tree-ensemble (GENIE3, GRNBoost2) methods, and infer transcription-factor protein activity from regulons with VIPER and msVIPER. Covers the activity-not-edges paradigm, the undirected-association caveat, the DREAM5 wisdom-of-crowds and method-complementarity result, AUPRC-over-AUROC evaluation, and gold-standard incompleteness. Use when inferring a regulatory network from a bulk expression matrix, finding master regulators, or scoring TF activity from a signature. For single-cell motif-pruned regulons see scenic-regulons; for co-expression modules see coexpression-networks.
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lilinji/GeneTind-Life-Skills☆ 152026년 8월 21일 업데이트
Detects m6A modifications from Oxford Nanopore direct-RNA-seq (DRS) signal using m6Anet (multiple-instance-learning over DRACH 5-mer signal). Covers the upstream pipeline (Dorado/Guppy basecalling -> minimap2 map-ont -> nanopolish eventalign -> m6anet dataprep -> m6anet inference), per-site vs per-read probability including the mod_ratio stoichiometry column, the DRACH-only constraint, minimum-coverage thresholds (20-50 reads/site), multi-condition comparison via xPore/Nanocompore/ELIGOS, Dorado native modification calling (RNA004, 2024+), and the cDNA-vs-DRS distinction (cDNA Nanopore CANNOT detect modifications). Use when calling m6A from ONT DRS without immunoprecipitation, choosing m6Anet vs xPore vs Nanocompore vs ELIGOS vs Dorado native, interpreting probability_modified vs mod_ratio vs per-read probabilities, deciding between m6Anet (known DRACH sites) and Dorado/Remora (genome-wide screening), pinning RNA002 vs RNA004 chemistry and basecaller versions, or troubleshooting eventalign/dataprep failures.
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lilinji/GeneTind-Life-Skills☆ 152026년 8월 21일 업데이트
Performs differential expression on bulk RNA-seq count data with edgeR's negative-binomial GLM and quasi-likelihood F-test framework. Covers DGEList construction, filterByExpr, TMM/TMMwsp normalization, robust dispersion estimation, glmQLFit/glmQLFTest, TREAT for magnitude-bounded hypotheses, contrasts via no-intercept designs, voom and voomWithQualityWeights for heterogeneous samples, and the edgeR v4 bias-corrected APL changes. Use when running bulk DE with edgeR, choosing edgeR over DESeq2 (small n, transcript DE via catchSalmon, large samples), needing TREAT for a fold-change-threshold hypothesis, troubleshooting v3-to-v4 reproducibility, building paired or interaction designs, or handling library-quality heterogeneity.
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lilinji/GeneTind-Life-Skills☆ 152026년 8월 21일 업데이트
Identifies super-enhancers from H3K27ac, MED1, or BRD4 ChIP-seq using ROSE, ROSE2, LILY, HOMER -style super, and ENCODE dELS cross-referencing. Handles peak stitching parameters, ranking choices, hockey-stick inflection, marker choice (H3K27ac vs MED1/BRD4), and cross-condition comparison with spike-in normalization. Constructs core regulatory circuitry (Saint-Andre 2016) from SE-encoded TFs. Use when identifying cell-identity / cancer-associated regulatory domains, comparing super-enhancers between conditions, identifying master transcription factor networks, or predicting BET-inhibitor responsiveness.
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lilinji/GeneTind-Life-Skills☆ 152026년 8월 21일 업데이트
Detects allele-specific transcription factor or histone modification binding from heterozygous-variant ChIP-seq using WASP (reference-bias filter; mandatory upstream), RASQUAL (joint QTL + bias-corrected testing), BaalChIP (Bayesian beta-binomial with copy-number-aware overdispersion), and AlleleSeq (personalized diploid genome). Handles imprinted-locus awareness, X-inactivation artifacts, cancer copy-number imbalance, and integration with downstream caQTL / bQTL mapping. Use when identifying variants with allelic effects on TF binding, fine-mapping causal regulatory variants, validating deep-learning variant predictions, or characterizing cis-acting regulatory effects.
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lilinji/GeneTind-Life-Skills☆ 152026년 8월 21일 업데이트
Performs gene-level association from GWAS summary statistics via genetically predicted tissue expression using FUSION, PrediXcan, S-PrediXcan, S-MultiXcan, UTMOST, MOSTWAS, kTWAS, EpiXcan, TIGAR-V2, and probabilistic fine-mapping with FOCUS and MA-FOCUS. Use when running TWAS from GWAS sumstats, prioritising candidate causal genes from a GWAS lead locus, picking single-tissue vs cross-tissue models, identifying LD-induced TWAS false positives, choosing ancestry-matched prediction weights, fine-mapping co-regulated TWAS hits, or triangulating TWAS with cis-eQTL Mendelian randomization and colocalization to nominate a causal gene.
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lilinji/GeneTind-Life-Skills☆ 152026년 8월 21일 업데이트
Bulk-query Ensembl BioMart (and other BioMart instances) for cross-database ID mapping, gene/transcript/exon coordinates, and ortholog tables. Use when batch-converting Ensembl IDs to other namespaces (HGNC, RefSeq, UniProt, Entrez), pulling gene coordinate tables for thousands of genes, building ortholog wide-tables across species, or replacing slow Ensembl REST loops with one-shot bulk export. Encodes BioMart's XML query format, R biomaRt vs Python pybiomart trade-off, mart-vs-dataset hierarchy, and the URL endpoint that's BioMart-specific (separate from rest.ensembl.org).
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lilinji/GeneTind-Life-Skills☆ 152026년 8월 21일 업데이트
Detect transcription factor binding footprints in ATAC-seq using TOBIAS, HINT-ATAC, Wellington, or scprinter. Use when identifying bound TF sites within accessible regions, correcting Tn5 insertion bias before footprinting, choosing between cleavage-based and aggregate-based footprinters, or comparing differential TF activity between conditions.
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lilinji/GeneTind-Life-Skills☆ 152026년 8월 21일 업데이트
Process and generate multimedia content using Google Gemini API. Capabilities include analyze audio files (transcription with timestamps, summarization, speech understanding, music/sound analysis up to 9.5 hours), understand images (captioning, object detection, OCR, visual Q&A, segmentation), process videos (scene detection, Q&A, temporal analysis, YouTube URLs, up to 6 hours), extract from documents (PDF tables, forms, charts, diagrams, multi-page), generate images (text-to-image, editing, composition, refinement). Use when working with audio/video files, analyzing images or screenshots, processing PDF documents, extracting structured data from media, creating images from text prompts, or implementing multimodal AI features. Supports multiple models (Gemini 2.5/2.0) with context windows up to 2M tokens.
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lilinji/GeneTind-Life-Skills☆ 152026년 8월 21일 업데이트
Process images, video, audio, PDFs with Gemini API. Generate images (Nano Banana 2), videos (Veo 3), speech (MiniMax TTS), music (MiniMax). Convert documents to Markdown. Multi-provider fallback (Gemini → MiniMax → OpenRouter). Activate when task references media files, asks to analyze/describe/transcribe/extract/generate/convert, or involves non-text binary files.
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ngocsangyem/MeowKit☆ 152026년 7월 28일 업데이트
Read-only audit of `.claude/` structural overhead. Reports prioritized "remove X save Y tokens" recommendations against the model context window. NOT for monetary cost tracking — that's /mk:budget. NOT for transcript size monitoring — long-session continuity defers to Claude Code native compaction. NOT for runtime context decisions (what to read, when to compact) — see mk:context-engineering. Use when planning to add context capacity, diagnosing perceived slowdowns, or auditing health.
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ngocsangyem/MeowKit☆ 152026년 7월 28일 업데이트
다중 세션 transcript에서 반복 실패 패턴(instinct)을 자동 채굴하여 신규 skill candidate 생성
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baekenough/second-brain☆ 152026년 10월 8일 업데이트
Annotate speech/TTS datasets with per-clip quality metrics (MOS, SNR, STOI, pitch, bandwidth, speaking rate, WER/CER, gender/emotion), multi-ASR consensus transcription and speaker labeling using the audiogear pipeline; then filter clips by quality and build listenable HTML QA reports. Use when asked to compute audio dataset metrics, build extended_metadata.csv, transcribe unlabeled audio, select clean TTS training data, or QA a speech dataset.
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lIkesimba9/audiogear☆ 142026년 7월 20일 업데이트
YouTube transcripts to summaries, threads, blogs.
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kevinnft/ai-agent-skills☆ 142026년 8월 1일 업데이트
Azure OpenAI SDK for .NET. Client library for Azure OpenAI and OpenAI services. Use for chat completions, embeddings, image generation, audio transcription, and assistants.
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sinhoneyy/master-skills☆ 142026년 9월 5일 업데이트