Analyzes CUT&RUN (Skene Henikoff 2017) and CUT&Tag (Kaya-Okur 2019) chromatin profiling data. Handles SEACR vs MACS2 peak calling (with the btaf375 2025 benchmark guidance), pA-MNase vs pA-Tn5 vs pAG-Tn5 chimera differences, E. coli spike-in carryover normalization, IgG-only control logic (no input), characteristic fragment-size signatures (25-75 bp for CUT&Tag), and lower depth requirements (5M reads typical vs 25M for ChIP). Use when calling peaks from CUT&RUN/CUT&Tag, scaling by E. coli spike-in carryover, choosing SEACR norm mode, or comparing CUT&RUN/Tag results to traditional ChIP.
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peacezha/HPClaw☆ 32026년 10월 11일 업데이트
Segments the genome into chromatin states from combinatorial histone modification and chromatin factor ChIP-seq data. Uses ChromHMM (multivariate HMM on binarized signal, v1.27), Segway (Dynamic Bayesian Network on continuous signal), EpiSegMix (flexible-distribution HMM with duration modeling, 2024), EpiLogos (multi-biosample visualization), IDEAS (cell-type-aware joint), and full-stack ChromHMM (Vu Ernst 2022) for cross-cell-type segmentations. Handles state-count selection (15 vs 18 vs 25 states), binarization choice, OverlapEnrichment / NeighborhoodEnrichment downstream analysis, and cross-biosample integration. Use when learning chromatin states from a histone mark panel, characterizing learned states by genomic feature enrichment, or comparing chromatin landscapes across cell types.
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peacezha/HPClaw☆ 32026년 10월 11일 업데이트
Detects allele-specific transcription factor or histone modification binding from heterozygous-variant ChIP-seq using WASP (reference-bias filter; mandatory upstream), RASQUAL (joint QTL + bias-corrected testing), BaalChIP (Bayesian beta-binomial with copy-number-aware overdispersion), and AlleleSeq (personalized diploid genome). Handles imprinted-locus awareness, X-inactivation artifacts, cancer copy-number imbalance, and integration with downstream caQTL / bQTL mapping. Use when identifying variants with allelic effects on TF binding, fine-mapping causal regulatory variants, validating deep-learning variant predictions, or characterizing cis-acting regulatory effects.
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peacezha/HPClaw☆ 32026년 10월 11일 업데이트
Designs PROTACs, molecular glues, and bivalent degraders with explicit handling of E3 ligase choice (VHL, CRBN, IAP, MDM2, KEAP1), linker design (length, composition, rigidity), ternary complex prediction (PRosettaC, DeepTernary, AlphaFold3 with constraints), cooperativity (alpha), DC50 / Dmax characterization, hook effect, and prediction-experiment reconciliation. Use when designing targeted protein degraders, planning linker SAR, predicting ternary complex stability, or building generative degrader workflows.
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peacezha/HPClaw☆ 32026년 10월 11일 업데이트
Map nucleosome center positions, occupancy, and fuzziness from ATAC-seq fragment-size patterns using NucleoATAC, ATACseqQC, DANPOS3, or scprinter. Use when characterizing nucleosome organization at promoters and enhancers, calling +1/-1 nucleosomes flanking NFRs, generating V-plots for chromatin structure visualization, or comparing nucleosome positioning between conditions.
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peacezha/HPClaw☆ 32026년 10월 11일 업데이트
Expert in cluttering -- the lesser-known fluency disorder characterized by rapid/irregular speech rate, excessive disfluencies, and frequent ADHD comorbidity. Covers differential diagnosis from stuttering, assessment protocols, therapy approaches (rate control, self-monitoring, pragmatic awareness), technology-assisted intervention, and AI tools for people who clutter. Activate on 'cluttering', 'rapid speech disorder', 'speech rate too fast', 'speech disfluency not stuttering', 'disorganized speech', 'ADHD speech problems', 'cluttering vs stuttering', 'speech intelligibility', 'mazed speech', 'telescoping words'. NOT for stuttering-only treatment (overlap is common but they are distinct), hearing disorders, or voice disorders (pitch, resonance).
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curiositech/port-daddy☆ 32026년 10월 18일 업데이트
AIエージェントのキャラクター定義ファイルを生成するスキル。ユーザーがキャラクター設定(名前、二つ名、年齢、属性、性格、支配の流儀、口癖、外見、絵文字など)を入力すると、それに基づいてIDENTITY.md、SOUL.md、USER.md、AGENTS.md、TOOLS.md、BOOTSTRAP.md、HEARTBEAT.mdの7つのファイルとavatar.pngを配置したキャラクターディレクトリを作成する。また、agent-identity/README.md にキャラクター情報とアバター画像を追加する。ユーザーが「キャラクターを作って」「新しいキャラクターを追加して」「○○っていうキャラクターのファイル作って」と言った時や、キャラクター設定を詳細に提供した時に使用する。
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Sunwood-AI-OSS-Hub/zero-cc☆ 32026년 2월 17일 업데이트
既存キャラクター画像を、承認制でピクセルアートの正準画像へ変換し、3状態パイロット、クロマ前処理、状態間ジオメトリ検証、9状態生成、遷移QA、仮配置、アプリ内確認、ロールバック可能な正式配置まで行う。キャラクターからCodexペットを作る依頼に加え、ジャンプで小さくなる、状態ごとに身長が変わる、足元が跳ねる、クロマ縁が出る、アニメーションを修復したい依頼で使用する。
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
ryryo/dot-claude-dev☆ 32026년 10월 18일 업데이트
This skill should be used when the user wants to "test a claim against data", "validate an empirical hypothesis", "refine a model/theory with evidence", "characterize a pattern and verify it", "演繹と帰納で検証", "仮説をデータで検証して更新", "実例と反例で確かめる", "弁証法ループ", "主張を現物で裏取り", "傾向分析を検証して精緻化", or mentions iteratively updating a hypothesis by deriving predictions and testing them against a real corpus. NOTE: Use this for VALIDATING/REFINING an empirical claim or model against real data through a derive→test→update loop. Use strong-inference for debugging an UNKNOWN cause, and devils-advocate for adversarially stress-testing a DESIGN proposal.
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masuP9/agent-dialectics☆ 32026년 9월 16일 업데이트
Amplify safe or boring designs to make them more visually interesting and stimulating. Increases impact while maintaining usability. Use when the user says the design looks bland, generic, too safe, lacks personality, or wants more visual impact and character.
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waynesutton/waynesutton-ai☆ 22026년 9월 8일 업데이트
Use when writing recommendation letters, reference letters, or award nominations for students, postdocs, or colleagues. Invoke when user mentions recommendation letter, reference, nomination, letter of support, endorsement, or needs help with strong advocacy, comparative statements, or evidence-based character assessment.
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MikeCheng1208/BattleTree☆ 22026년 7월 22일 업데이트
Comprehensive China A-share stock analysis covering fundamental analysis, technical analysis, policy impact assessment, and market-specific features (T+1 trading, price limits, northbound capital flow). Use when user asks about A股分析, Chinese mainland stocks, Shanghai/Shenzhen listed stocks, or needs analysis considering China market characteristics.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
MikeCheng1208/BattleTree☆ 22026년 7월 22일 업데이트
Amplify safe or boring designs to make them more visually interesting and stimulating. Increases impact while maintaining usability. Use when the user says the design looks bland, generic, too safe, lacks personality, or wants more visual impact and character.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
MMEHDI0606/ai-agent-foundation-template☆ 22026년 5월 21일 업데이트
Translates or rewrites Chinese text into English using a 'critical dialogue' tone, characterized by engaging questions, analytical commentary, and a conversational flow while preserving citations and facts.
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David-Li0406/meta-skill-evloving☆ 22026년 7월 14일 업데이트
Guardian Angel gives AI agents a moral conscience rooted in Thomistic virtue ethics. Rather than relying solely on rule lists, it cultivates stable virtuous dispositions— prudence, justice, fortitude, temperance—that guide every interaction. The foundation is caritas: willing the good of the person you serve. From this flow the cardinal virtues as practical habits of right action and sound judgment. v3.0 introduced virtue-based disposition as the primary evaluation layer, providing deeper coherence than checklists alone. The agent's character becomes the safeguard. v3.1 adds: Plugin enforcement layer with before_tool_call hooks, approval workflows for ambiguous cases, and protections for sensitive infrastructure actions.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
aAAaqwq/openclaw-team☆ 22026년 6월 18일 업데이트
Count words, characters, sentences, paragraphs, and reading time for any text using AceToolz.
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Lord1Egypt/awesome-skill-forge☆ 22026년 6월 10일 업데이트
Creates optimized meta titles, descriptions, and URL suggestions based on character limits and best practices. Generates compelling, keyword-rich metadata. Use PROACTIVELY for new content.
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itsimonfredlingjack/codex-dev-plugin☆ 22026년 2월 5일 업데이트
Detects ransomware encryption activity in real time using entropy analysis, file system I/O monitoring, and behavioral heuristics. Identifies mass file modification patterns, abnormal entropy spikes in written data, and suspicious process behavior characteristic of ransomware encryption routines. Activates for requests involving ransomware behavioral detection, entropy-based file monitoring, I/O anomaly detection, or real-time encryption activity alerting.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
aniket2348823/Vul-Agent☆ 22026년 6월 9일 업데이트
Bluetooth Low Energy (BLE) attack methodology — GATT enumeration, characteristic read/write without auth, pairing downgrade (Just Works forced), LE Secure Connections bypass, MITM via active relay, sniffing with Sniffle (TI CC1352) / Ubertooth / Frontline, encryption key extraction (LE Legacy Pairing crackable, LE Secure Connections strong), proximity authentication abuse (cars, locks), and companion-app trust analysis. Use for IoT BLE devices, smart locks, fitness trackers, medical devices, BLE beacons, or any device pairing over BLE.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
ajtazer/heckit☆ 22026년 10월 7일 업데이트
Hunting skill for auth bypass vulnerabilities. Built from 12 public bug bounty reports across SAML XSW / parser-differential (GitHub Enterprise CVE-2025-25291/25292), SAML signature stripping (Uber, Rocket.Chat, samlify CVE-2025-47949), SAML domain enforcement bypass via control characters (HackerOne 2024), partner-portal cross-IdP assertion reuse (Slack), WordPress XMLRPC bypassing SSO (Uber), JWT alg-confusion HS256/RS256 (Jitsi), JWT signature-validation skip (Linktree, Newspack), and token-audience confusion (Argo CD CVE-2023-22482). For standalone JWT signature/crypto forging (alg:none, key confusion, kid/jku) see hunt-jwt-crypto; this skill covers JWT only inside SSO/SAML/token-trust bypass chains. SAML assertion-layer attacks (XSW, comment injection, signature stripping, XXE-in-assertion) are owned by hunt-saml; this skill owns the broader cross-protocol auth-bypass taxonomy. Use when hunting auth bypass — see the Legacy-Protocol Matrix for branded-UI vs legacy-endpoint patterns.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
ajtazer/heckit☆ 22026년 10월 7일 업데이트
Hunt LDAP Injection and XPath Injection — authentication bypass, blind char-by-char attribute exfiltration, AD user/group enumeration, XML-store XPath bypass. Covers the LDAP special-character set (* ( ) NUL /), search-filter-context vs DN-injection, parenthesis-balancing, AND/OR filter logic, and {SSHA}/{CRYPT} userPassword exfil on non-AD directories. Use when target uses LDAP/AD authentication, corporate SSO with a directory backend, an address-book/people-search API, or XML-based data stores queried with XPath.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
ajtazer/heckit☆ 22026년 10월 7일 업데이트
Send personalized LinkedIn direct messages to a list of existing 1st-degree connections via browser automation. Use when the user wants to message LinkedIn connections with AI-personalized outreach — e.g. nurturing leads, following up after events, reconnecting with contacts, or announcing something. Takes a data file (CSV/TSV) or plain list with connection names and companies, asks for outreach context/goal, generates a tailored message per person, and sends each one via browser automation. Handles message compose flow, character limits, and incremental status tracking.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
johnalbertini14-glitch/openclaw-skills☆ 22026년 2월 26일 업데이트
Analyze any codebase's source code in depth and produce structured analysis documents saved as markdown files. Use this skill whenever the user asks to understand how a codebase works — architecture, module design, call flows, data models, design patterns, performance characteristics, or any implementation detail. Trigger on phrases like "analyze the source", "explain this code", "how does X work", "where is Y implemented", "trace the flow of", "what happens when", "read through the code", "code walkthrough", "源码分析", "代码解读", "实现原理", "架构分析", "调用链路", "模块分析", or any code-exploration request. Works with any programming language: TypeScript/JavaScript, Java, Python, Go, Rust, C/C++, and more. Even if the user's question seems simple (e.g., "这个文件是干什么的"), use this skill — a thorough, source-backed analysis document is always more valuable than a surface-level guess.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
Scoheart/agentskills☆ 22026년 8월 4일 업데이트
Requires OFOX_API_KEY — create one at https://app.ofox.ai. Shared execution layer for the Ofox image API (api.ofox.ai) — validates parameters client-side, sends one synchronous request, base64-decodes the result, saves it to a file, and reports the real usage token counts and the computed dollar cost. Does both text-to-image (generate) and editing an existing image you supply as a local file (edit — change the background, recolour an element, alter a product photo, while leaving the rest of the picture intact). This is a library skill, not a standalone user-facing one — it is meant to be invoked by scenario skills that build model/prompt/size choices for a specific use case and then call into this skill's script rather than re-implementing the API calls — image-edit owns "change this image so that...", product-image owns a set of product images to choose between, and seedance-anime-drama owns character images for a video pipeline. Load this skill directly only when a user explicitly names the Ofox image API, asks to call it with specific low-level parameters, asks to debug a failed Ofox image request, or wants a plain "generate an image of..." from text — which is the one common case no scenario skill covers.
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ofoxai/skills☆ 22026년 9월 22일 업데이트