Bulk-query Ensembl BioMart (and other BioMart instances) for cross-database ID mapping, gene/transcript/exon coordinates, and ortholog tables. Use when batch-converting Ensembl IDs to other namespaces (HGNC, RefSeq, UniProt, Entrez), pulling gene coordinate tables for thousands of genes, building ortholog wide-tables across species, or replacing slow Ensembl REST loops with one-shot bulk export. Encodes BioMart's XML query format, R biomaRt vs Python pybiomart trade-off, mart-vs-dataset hierarchy, and the URL endpoint that's BioMart-specific (separate from rest.ensembl.org).
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peacezha/HPClaw☆ 32026년 10월 11일 업데이트
Query and download from NCBI Gene Expression Omnibus (GEO) and EMBL-EBI's BioStudies/ArrayExpress mirror. Use when finding expression datasets, navigating SuperSeries vs SubSeries, choosing between series-matrix (submitter-normalized) and raw supplementary files, downloading via GEOparse (Python) or GEOquery (R/Bioconductor), linking GEO to SRA for raw reads, or distinguishing GSE/GSM/GPL/GDS record types. Encodes the SuperSeries trap, the series-matrix normalization-trust caveat, GEOmetadb deprecation, ArrayExpress migration to BioStudies, and processed-vs-raw decision matrix.
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peacezha/HPClaw☆ 32026년 10월 11일 업데이트
Predict RBP binding from RNA sequence using deep learning models (RBPNet sequence-to-signal, RNAProt RNN, GraphProt2 GCN with structure, DeepCLIP, DeepRiPe multi-modal CNN) for variant-effect prediction, in silico binding-site discovery, model interpretation, and transfer learning from CLIP and RBNS datasets. Use when computational prediction of RBP binding from sequence is needed, evaluating variant effects on binding without further wet-lab experiments, comparing model performance, or training a custom model on ENCODE eCLIP data.
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peacezha/HPClaw☆ 32026년 10월 11일 업데이트
Standardizes molecular structures using ChEMBL chembl_structure_pipeline and RDKit rdMolStandardize covering sanitization, salt/solvent stripping, neutralization, tautomer canonicalization, stereochemistry standardization, mixture handling, and isotope normalization. Explicitly compares ChEMBL pipeline, canSARchem, and PubChem standardization choices. Use when preparing libraries for QSAR training, joining datasets across sources, deduplicating compound collections, or building canonical compound registries.
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peacezha/HPClaw☆ 32026년 10월 11일 업데이트
Reads, validates, and prepares CDISC SDTM and ADaM clinical trial data for analysis. Covers SDTM domain joins (DM, AE, EX, VS, LB, DS), ADaM architecture (ADSL, BDS, OCCDS, ADTTE) with traceability, treatment-emergent AE conventions, baseline derivation, SUPPQUAL/NSV handling, Define-XML 2.1, and Pinnacle 21 / CORE validation. Use when working with clinical trial datasets in CDISC SDTM/ADaM format, preparing analysis-ready data, or validating for regulatory submission.
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peacezha/HPClaw☆ 32026년 10월 11일 업데이트
Perform multiple sequence alignment using MAFFT, MUSCLE5, ClustalOmega, or T-Coffee. Guides tool and algorithm selection based on dataset size, sequence divergence, and downstream application. Use when aligning three or more homologous sequences for phylogenetics, conservation analysis, or evolutionary studies.
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peacezha/HPClaw☆ 32026년 10월 11일 업데이트
Use when running analytical SQL over Parquet/CSV/JSON without a warehouse, replacing pandas for data wrangling, joining S3 data in-place, building local data marts, or embedding OLAP into an app. Triggers: read_parquet/read_csv setup, partitioned dataset queries, hive partitioning, glob patterns for S3, COPY TO export, attach Postgres/MySQL, UDFs in Python/R, MotherDuck cloud sync, columnar performance vs row stores. NOT for OLTP workloads (concurrent writes), distributed analytics at petabyte scale (use Spark/Trino), or vector search (use pgvector/Lance).
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curiositech/port-daddy☆ 32026년 10월 19일 업데이트
Design RL simulation sandboxes, trajectory datasets, QLoRA/LoRA adaptation plans, eval harnesses, and rollback unhooks for agents learning specific coding behaviors beyond the base model. Use when building or reviewing tool-use training loops, offline trajectories, reward functions, self-improvement harnesses, or Port Daddy agent behavior curricula. NOT for generic ML tutorials, full model training operations, or production deployment without eval gates and safety unhooks.
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curiositech/port-daddy☆ 32026년 10월 19일 업데이트
Azure AI Projects SDK for .NET. High-level client for Azure AI Foundry projects including agents, connections, datasets, deployments, evaluations, and indexes.
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MMEHDI0606/ai-agent-foundation-template☆ 22026년 5월 21일 업데이트
Azure AI Projects SDK for Java. High-level SDK for Azure AI Foundry project management including connections, datasets, indexes, and evaluations.
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MMEHDI0606/ai-agent-foundation-template☆ 22026년 5월 21일 업데이트
Azure Machine Learning SDK v2 for Python. Use for ML workspaces, jobs, models, datasets, compute, and pipelines.
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MMEHDI0606/ai-agent-foundation-template☆ 22026년 5월 21일 업데이트
Use this skill when working with scientific research tools and workflows across bioinformatics, cheminformatics, genomics, structural biology, proteomics, and drug discovery. This skill provides access to 600+ scientific tools including machine learning models, datasets, APIs, and analysis packages. Use when searching for scientific tools, executing computational biology workflows, composing multi-step research pipelines, accessing databases like OpenTargets/PubChem/UniProt/PDB/ChEMBL, performing tool discovery for research tasks, or integrating scientific computational resources into LLM workflows.
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David-Li0406/meta-skill-evloving☆ 22026년 7월 14일 업데이트
Legal contract analysis using CUAD dataset (41 risk categories). Supports NDA, SaaS, M&A, employment, payment/merchant, and finder/broker agreements. Identifies red flags, suggests redlines, compares to market standards.
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aAAaqwq/openclaw-team☆ 22026년 6월 18일 업데이트
Debug LLM applications using the Phoenix CLI. Fetch traces, analyze errors, review experiments, inspect datasets, and query the GraphQL API. Use when debugging AI/LLM applications, analyzing trace data, working with Phoenix observability, or investigating LLM performance issues.
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jcasnellie69/homelab-config☆ 22026년 10월 16일 업데이트
Set up eval-based QA for Python LLM applications: instrument the app, build golden datasets, write and run eval tests, and iterate on failures. ALWAYS USE THIS SKILL when the user asks to set up QA, add tests, add evals, evaluate, benchmark, fix wrong behaviors, improve quality, or do quality assurance for any Python project that calls an LLM model.
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jcasnellie69/homelab-config☆ 22026년 10월 16일 업데이트
Generate deep links to the Arize UI. Use when the user wants a clickable URL to open a specific trace, span, session, dataset, labeling queue, evaluator, or annotation config.
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jcasnellie69/homelab-config☆ 22026년 10월 16일 업데이트
GPU-accelerated data curation for LLM training. Supports text/image/video/audio. Features fuzzy deduplication (16× faster), quality filtering (30+ heuristics), semantic deduplication, PII redaction, NSFW detection. Scales across GPUs with RAPIDS. Use for preparing high-quality training datasets, cleaning web data, or deduplicating large corpora.
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Lord1Egypt/awesome-skill-forge☆ 22026년 6월 10일 업데이트
Builds repeatable evaluation systems with golden datasets, scoring rubrics, pass/fail thresholds, and regression reports. Use for "LLM evaluation", "testing AI systems", "quality assurance", or "model benchmarking".
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sathishssj3/Stereix-Engine☆ 22026년 10월 4일 업데이트
Triage ASM/recon output for ownership before testing — separate the target's real assets from namespace-collision noise. Automated recon keyword-matches on the brand name, so for any target whose name is a common/dictionary word, the output is dominated by assets belonging to UNRELATED same-named companies (repos, cloud buckets, mobile apps, breach corpora, typosquats). Built from an authorized engagement where an ASM report's 'Criticals' were overwhelmingly false positives and the combo/repos/mobile/bucket lists were polluted with unrelated same-named orgs. Use at the START of any engagement, immediately on receiving any ASM/recon/OSINT dataset, BEFORE testing anything.
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ajtazer/heckit☆ 22026년 10월 7일 업데이트
Expert in Langfuse - the open-source LLM observability platform. Covers tracing, prompt management, evaluation, datasets, and integration with LangChain, LlamaIndex, and OpenAI. Essential for debugging, monitoring, and improving LLM applications in production. Use when: langfuse, llm observability, llm tracing, prompt management, llm evaluation.
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danstrem2/clawdbot-skill-master-pack☆ 22026년 2월 1일 업데이트