276건 · 관련도순
Use Boltz-2 to predict structures of complexes containing proteins, DNA, RNA, and small molecules. Obtain structure files and confidence scores to assess designed binders, with optional predictions of binding strength between a protein and a small molecule.
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Review EVM and Solana meme coins for hidden minting, blocked sales, adjustable fees, and liquidity withdrawal risks. The skill guides source checks and on-chain verification to identify privileged controls that could enable a rug pull.
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Assess on-premises SharePoint Server for exposed information, legacy login paths, and conditions associated with known vulnerabilities. It guides evidence collection and helps distinguish meaningful security findings from misleading error messages.
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Generate TRES Finance reports as CSV or XLSX files, including transaction ledgers, balances, and cost basis reports. Verify that the export was actually created, monitor its completion, and return a download link.
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Use the Notion API to search, create, and update pages and databases, read or append page content, change item properties, and retrieve records using filters and sorting.
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Review the technology choices in an implementation plan using past project outcomes and web research. Produce a report that identifies outdated approaches, deprecated tools, and security concerns, with supporting sources and suggested alternatives.
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Turn feature requests and conversation context into an implementation plan and handoff document. Review existing code, clarify complex requirements, and organize concrete tasks, affected files, verification steps, assumptions, and risks for review before implementation.
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Researches library documentation, implementation practices, and specific web pages using Nia, Perplexity, and Firecrawl through MCP tools. Produces a handoff document with findings, available code examples, recommendations, pitfalls, and source links for another agent.
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Research library usage, recommended approaches, and general topics using external documentation and web sources. Choose a brief or thorough investigation, then organize examples, pitfalls, comparisons, and source links into a research document or implementation handoff.
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Investigate how an existing codebase works and document its components, connections, and file references. Combine current code findings with historical notes to produce a research document grounded in specific paths and line numbers.
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Search US patent and trademark records through USPTO APIs. Retrieve examination histories, citations, ownership transfers, and registration status to support prior art research, meaning searches for earlier inventions, and analysis of company patent and trademark holdings.
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Generate prompts for AI image tools to produce modern ML/RL paper-style figures matching the aesthetic of recent ICLR/NeurIPS/ICML 2024-2025 publications. Key traits — pure white canvas, white panels with soft drop shadow, rounded friendly font (Nunito/Poppins), densely packed but uncluttered floating elements, small pastel token squares, rich inline illustrations, colored keyword text, pill-shaped concept labels. Trigger phrases — "pastel风格论文配图", "现代ML论文配图", "modern ML figure prompt".
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This is a summary the advantages and disadvantages of earthquake event detection and phase picking methods, shared by leading seismology researchers at the 2025 Earthquake Catalog Workshop. Use it when you have a seismic phase picking task at hand.
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Implement mHC (Manifold-Constrained Hyper-Connections) for stabilizing deep network training. Use when implementing residual connection improvements with doubly stochastic matrices via Sinkhorn-Knopp algorithm. Based on DeepSeek's 2025 paper (arXiv:2512.24880).
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Elite AI context engineering specialist mastering dynamic context management, vector databases, knowledge graphs, and intelligent memory systems. Orchestrates context across multi-agent workflows, enterprise AI systems, and long-running projects with 2024/2025 best practices. Use PROACTIVELY for complex AI orchestration.
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Elite AI-powered customer support specialist mastering conversational AI, automated ticketing, sentiment analysis, and omnichannel support experiences. Integrates modern support tools, chatbot platforms, and CX optimization with 2024/2025 best practices. Use PROACTIVELY for comprehensive customer experience management.
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Elite content marketing strategist specializing in AI-powered content creation, omnichannel distribution, SEO optimization, and data-driven performance marketing. Masters modern content tools, social media automation, and conversion optimization with 2024/2025 best practices. Use PROACTIVELY for comprehensive content marketing.
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Elite code review expert specializing in modern AI-powered code analysis, security vulnerabilities, performance optimization, and production reliability. Masters static analysis tools, security scanning, and configuration review with 2024/2025 best practices. Use PROACTIVELY for code quality assurance.
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OWASP Top 10 for LLM Applications (2025) knowledge base for identifying, assessing, and remediating large language model security risks.
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OWASP Top 10 for Web Applications (2025) knowledge base for identifying, assessing, and remediating web application security risks.
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Personal-data-protection compliance reference for engineers building applications subject to Singapore PDPA, Indonesia UU PDP, Thailand PDPA, Malaysia PDPA, Philippines DPA (RA 10173), or Vietnam PDPL (91/2025/QH15). Use when reviewing or modifying code that touches personal data — signup/auth/consent, data export, account deletion, retention/purging, admin access to personal-data stores, third-party processors, breach response, or privacy/T&C documents.
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Tests genotype-environment associations and identifies adaptive loci while correcting for the four-confound landscape (structure, demography, background selection, sampling design) using LFMM2 with mandatory K via sNMF cross-entropy elbow (LEA 3), BayPass Core/AUX/C2/IS with Omega covariance matrix, RDA / pRDA for polygenic adaptation (Forester 2018; requires imputed genotypes), OutFLANK with trimmed FST null, pcadapt, gradient forests (Ellis-Smith-Pitcher 2012, NOT mis-cited Ellis-Manel), Capblancq & Forester 2021 RDA Swiss-army-knife, genomic-offset prediction with Lind & Lotterhos 2025 three-regime caveat, Lotterhos-Whitlock sampling optima, Wang & Bradburd 2014 IBD vs IBE, and Circuitscape + ResistanceGA. Use when identifying adaptive loci across gradients, choosing K for LFMM2, deciding among GEA methods, predicting maladaptation with the novel-environment caveat, distinguishing IBD vs IBE, or optimizing sampling design.
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Designs and analyzes in vivo CRISPR screens in animal tumor models, organoids, and immune-cell adoptive transfers. Covers bottleneck math (250x cells/sgRNA requires ~25M cells implanted; impossible for most syngeneic models, forcing focused libraries), focused library design (Manguso 2017 Nature 547:413 immune screen; Chen 2015 tumor screens), CRISPR-StAR intrinsic-control screening (Uijttewaal 2025 Nat Biotechnol 43:1848), clonal-dynamics-limited detection, tumor-explant DNA recovery, syngeneic vs xenograft vs PDX considerations, and the relationship to downstream MAGeCK / drugZ analysis. Use when designing in vivo CRISPR screens for tumor / immune / metastasis biology, choosing focused vs genome-wide for animal models, addressing bottleneck-induced clonal collapse, picking the syngeneic / xenograft / PDX model, integrating in vivo with in vitro results, or applying CRISPR-StAR for animal experiments.
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Designs adaptive clinical trials including group-sequential (O'Brien-Fleming, Pocock, Lan-DeMets spending), sample-size re-estimation (blinded Friede-Kieser, unblinded Cui-Hung-Wang, Mehta-Pocock promising zone), seamless Phase 2/3 with treatment-arm selection, population enrichment, and response-adaptive randomisation. Covers FDA 2019 Final Adaptive Designs Guidance, FDA 2022 Master Protocols, and ICH E20 Step 2b/3 draft (June 2025, NOT final). Use when planning interim analyses, sample-size re-estimation, or master/platform-trial designs.
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