'pir' 검색 결과

Cozy cafe-inspired interface with warm tones, soft typography, and clean layouts for a relaxed browsing experience.

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Build premium scroll-driven web pages and product showcases inspired by high-end app, hardware, and product interaction patterns. Use for Raycast-like, Apple-like, NVIDIA-like, RTX/GPU, SaaS, AI browser, parallax, sticky scroll, pinned reveal, Three.js GLB model, Web Audio sound effect, responsive accessibility, and performance-safe frontend requests.

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Raw, anti-design aesthetic inspired by concrete architecture with unadorned elements, jarring layouts, and functional minimalism.

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Notebook-collage weekly digest template — spiral-bound reporter's notebook aesthetic with cobalt tape, mint folder tab, binder clip, receipt block, ruled baseline grid; built for AI-product / team / design weekly digests delivered as a downloadable high-res page.

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Gera e testa ganchos — primeira linha de post, abertura de e-mail, headline de anúncio, texto de miniatura, título de vídeo. Use quando o usuário disser "gancho", "hook", "primeira linha", "abertura", "como começar o post", "ninguém passa da primeira linha", "chamada", "título que prenda", ou quando pedir variações de abertura. Trabalha por biblioteca de 9 padrões nomeados, não por inspiração. Para o texto completo, ver copy-social, copy-email ou copy-ads.

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Copy para setor público e saúde — linguagem cidadã, acessibilidade, LGPD e comunicação de política pública. Use quando o contexto for prefeitura, secretaria, SUS, assistência social, transparência ou governo digital, ou quando o usuário citar DashSaúde, Integra Arapiraca, ODARA, e-SUS ou APS.

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When the user wants to create or optimize in-app paywalls, upgrade screens, upsell modals, or feature gates. Also use when the user mentions "paywall," "upgrade screen," "upgrade modal," "upsell," "feature gate," "convert free to paid," "freemium conversion," "trial expiration screen," "limit reached screen," "plan upgrade prompt," "in-app pricing," "free users won't upgrade," "trial to paid conversion," or "how do I get users to pay." Use this for any in-product moment where you're asking users to upgrade. Distinct from public pricing pages (see page-cro) — this focuses on in-product upgrade moments where the user has already experienced value. For pricing decisions, see pricing-strategy.

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Analyze a set of design samples (HTML mockups + website URLs) and produce a structured style guide that anchors the rest of the stardust redesign pipeline. Use when the user supplies reference designs ("design samples", "mockups", "inspiration sites", "style references") and wants to extract a consistent visual language — type system, color palette, spacing, motion, and reusable component patterns — before redesigning a target site. Triggers on phrases like "distill these samples", "extract a style guide from these examples", "use these as design references", or "analyze these mockups". Outputs a `trait-matrix.json` (structured per-sample + cross-sample design tokens) and a `SAMPLES.md` narrative brief that `stardust:direct` reads under Mode B (anchor-reference precedence) when picking a redesign direction.

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Apply validated research paper insights to the current project codebase — improving architecture, code patterns, testing strategies, documentation, or workflows based on empirical findings. Load when learn-from-paper routes insights to the current project, or when the user asks to apply paper findings to this project, improve this codebase with research, use this paper to improve my project, or apply research to my code. Also triggers on "apply this to my project", "how can this paper help my codebase", "use these findings here", "implement paper recommendations", "use research to improve my code". Always called AFTER learn-from-paper has completed credibility and security checks — never ingests papers directly.

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Create a delightful, unexpected "wow" experience for the user by dynamically discovering and creatively combining other enabled skills. Triggers when the user says "surprise me" or any request expressing a desire for an unexpected creative showcase. Also triggers when the user is bored, wants inspiration, or asks for "something interesting".

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Extracts and analyzes competitors' ads from ad libraries (Facebook, LinkedIn, etc.) to understand what messaging, problems, and creative approaches are working. Helps inspire and improve your own ad campaigns.

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Fast, modern JavaScript/TypeScript development with the Bun runtime, inspired by [oven-sh/bun](https://github.com/oven-sh/bun).

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Design patterns for building autonomous coding agents, inspired by [Cline](https://github.com/cline/cline) and [OpenAI Codex](https://github.com/openai/codex).

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Batch effect correction for CRISPR screens covering ComBat empirical-Bayes, RUV, SVA, control-sgRNA normalization, and the model-based alternative of including batch as a covariate in MAGeCK MLE or Chronos. Covers screen-specific batch sources (passage cohort, library lot, infection day, sequencing run, Cas9 lot, FBS lot), PCA + variance-decomposition diagnostic to decide if correction is needed, when correction harms biology by over-correcting condition into batch, limma removeBatchEffect for visualization-only correction, and relationship to multi-condition design matrices. Use when combining screens for joint analysis, when passage cohort confounds biology, when DepMap-style panels need Chronos with batch covariates, when picking ComBat vs RUV, or when correction harms biology and should be replaced with explicit covariate modeling.

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Call protein-RNA binding sites from CLIP-seq BAM with CLIPper, PureCLIP, Skipper, Piranha, omniCLIP, CTK, CLAM, or Paraclu. Use when choosing between coverage-based, HMM-based, beta-binomial window-based, and crosslink-site-based peak callers; applying ENCODE eCLIP thresholds (log2 IP/SMInput >= 3, -log10 p >= 3); deciding when SMInput is mandatory; or reconciling peak-set discordance between callers for the same RBP.

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Prepares statistical reports for clinical trials following CONSORT 2025, SPIRIT 2025, ICH E9(R1) estimands, and FDA 2023 covariate adjustment guidance. Covers Table 1 generation, analysis populations (ITT/FAS/PP/Safety), the 5 ICH E9(R1) intercurrent-event strategies, MMRM under MAR (mmrm), reference-based MI (rbmi J2R/CR/CIR), Permutt tipping-point sensitivity, and Rubin's-rules vs frequentist variance debate. Use when preparing regulatory submissions, defining estimands, or implementing missing-data sensitivity analyses.

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Generates 3D conformer ensembles using RDKit ETKDGv3 with knowledge-enhanced distance geometry, MMFF94/UFF force-field optimization, CREST + GFN2-xTB semi-empirical refinement, and macrocycle-aware torsion preferences. Provides explicit decision rules for single vs ensemble conformer use, RMSD pruning, energy windows, conformer count, and force-field choice. Use when preparing 3D ligands for docking, generating descriptor input for 3D QSAR, or sampling macrocycle/peptide conformational ensembles.

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Predicts whether a DNA variant alters mRNA splicing using sequence-based deep-learning tools — SpliceAI (10kb context dilated CNN, clinical default), Pangolin (multi-tissue), MMSplice (modular per-region CNN with calibrated ΔPSI), SpliceTransformer/TrASPr (tissue-aware transformers), SpliceVault (empirical 300K-RNA lookup of likely mis-splicing outcomes), CADD-Splice (composite score). Applies the ClinGen SVI 2023 framework for ACMG/AMP variant interpretation (PVS1, PP3, BP4 evidence codes), HGVS splicing nomenclature (c.123+1G>A, c.123-3T>G, r.spl?), extended-window scoring for deep-intronic pseudoexons, tissue-specific predictions, branchpoint variant detection (BPHunter, LaBranchoR), and splice-switching ASO design. Use when interpreting splice impact of clinical variants, prioritizing VUS, identifying deep-intronic pathogenic variants, or designing ASOs.

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Detects differential alternative splicing between conditions using rMATS-turbo (binomial LRT on junction counts), leafcutter (Dirichlet-multinomial GLM on intron clusters), MAJIQ V3 deltapsi/HET (Bayesian posterior on LSVs), SUPPA2 (empirical-null on TPM-derived PSI), or Shiba (junction-imbalance-corrected, 2025 SOTA at low coverage). Reports FDR-corrected significance and delta PSI effect sizes. Tools differ in statistical model, annotation dependence, calibration regime, and replicate-count requirements. Use when comparing splicing patterns between treatment groups, tissues, or disease states.

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Use this skill when the user asks about Driver Qualification Files (DQF) — what must be in a DQ file under 49 CFR 391, retention periods, what's required pre-hire vs ongoing, document expiration tracking, audit-readiness for driver files, common DQF deficiencies that auditors find, or how to handle missing documents on existing drivers. Always cite the specific subsection of 49 CFR 391.

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Rigorous benchmarking of multi-agent coordination systems: experiment design, statistical analysis, human evaluation protocols, and reproducible reporting. NOT FOR ML model evaluation (use llm-evaluation-harness), A/B testing for web products, survey design, or general data science.

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Cooperative vibe coding across machines — real-time collaborative development with humans and AI agents. Covers current tools (Live Share, Code With Me, Zed, Cursor multiplayer, tmux), git-based async patterns, AI agent coordination, and the aspirational future of multi-human multi-agent development. Activate on: "pair programming", "vibe coding together", "collaborative coding", "mob programming", "remote pairing", "code together", "multiplayer coding", "Live Share", "Code With Me", "ensemble programming", "cooperative development". NOT for: building a real-time collaboration ENGINE (use real-time-collaboration-engine), git workflow mechanics (use git-best-practices), single-user AI coding assistance.

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Model an organization with BDI-inspired perceptions, expressed goals, accommodations, and levels of agency. Use for socio-technical diagnosis where actors interpret the same situation differently and agreement is partial. NOT for individual AgentSpeak execution, normative conflict algorithms, or ordinary workflow diagrams.

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Design or review a declared control-command profile and its verb/backend lifecycle matrix. Distinguish policy denial, unsupported capability, delivery acknowledgement, independently observed effect, and unknown outcome; bind authorization to principal, target, scope, current policy, expiry, and fencing epoch. NOT for claiming runtime correctness, proving an adapter from declarations, or approving a control-panel button without independent runtime evidence.

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