'dap' 검색 결과

Apply the aoa-safe-infra-change workflow inside an abyss-* repository using repo-relative operational surfaces, explicit local authority notes, rollback posture, and local validation commands. Use when the base infra-change workflow is correct but a thin project overlay is needed for one abyss repo. Do not use when the base skill is sufficient without local adaptation or when the task is really about producing a shareable artifact.

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Add documentation pages to an existing MkDocs + Entangled site, explain how to serve locally, help adapt documentation

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Use when communicating with neurodivergent users — adapts response structure, clarity, and pacing for ADHD, autism, and other neurotypes. Recommended base for all nd-* skills.

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Responds to security incidents in cloud environments (AWS, Azure, GCP) by performing identity-based containment, cloud-native log analysis, resource isolation, and forensic evidence acquisition adapted for ephemeral cloud infrastructure. Activates for requests involving cloud incident response, AWS security incident, Azure compromise, GCP breach, cloud forensics, or cloud identity compromise.

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Deploy Cisco Duo multi-factor authentication across enterprise applications, VPN, RDP, and SSH access points. This skill covers Duo integration methods, adaptive authentication policies, device trust

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How to author, edit, and adapt PostHog Signals scouts — the scheduled agents that scan a project and emit findings into the Signals inbox. Use when a user wants to customize a canonical scout for their own setup (narrow its scope, retune its thresholds, add disqualifiers), tweak a scout's schedule or dry-run posture, or write a brand-new scout from scratch for a specific use case (a custom event, a product surface no canonical scout covers). Covers the scout SKILL.md anatomy, the emit contract, the dedupe + scratchpad-memory conventions, the per-team skills-store path vs the canonical in-repo path, and the emit-and-inspect test loop (with dry-run as an optional safety net). Trigger on "write/edit/customize a signals scout", "new scout for X", "tune my scout schedule", "make a scout that watches <event>".

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Performs subgroup and heterogeneous treatment effect (HTE) analyses for clinical trials. Covers Mantel-Haenszel pooling, Breslow-Day, interaction tests in regression, RERI for additive interaction, modern data-adaptive HTE methods (STEPP, SIDES, causal forests, X/R-learners), Bayesian shrinkage (Dixon-Simon, MAP, EXNEX), graphical multiplicity (Bretz-Maurer), and credibility frameworks (Sun BMJ, EMA 2019). Use when analyzing treatment effects across patient subgroups for regulatory submissions or precision-medicine claims.

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End-to-end 16S/ITS amplicon workflow from demultiplexed FASTQ to a consensus differential-abundance result, orchestrating cutadapt primer removal, per-run DADA2 ASV inference (learnErrors/mergeSequenceTables/removeBimeraDenovo), region-matched taxonomy assignment, a SEPP/Greengenes2 tree, alpha/beta diversity at a declared sampling depth (phyloseq/vegan, adonis2 paired with betadisper), compositional DA as a consensus of >=2 tools (ALDEx2/ANCOM-BC2) on unrarefied counts, and optional PICRUSt2 functional prediction gated on NSTI. Covers the stage-ordering decisions (primers before truncation, per-run error model, rarefy for diversity not DA, predicted potential not activity) and defers each per-step choice to the six microbiome skills. Use when staging an amplicon study end to end or chaining ASV inference, taxonomy, diversity, and differential abundance. For shotgun reads see workflows/metagenomics-pipeline.

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Orchestrates an end-to-end MeRIP-seq / m6A-seq analysis from raw FASTQ to differential m6A peak calls and metagene plots, chaining fastp adapter trimming, STAR splice-aware alignment (NO deduplication for non-UMI MeRIP), deepTools replicate-concordance + IP-enrichment QC, PreSeq saturation curves, exomePeak2 (transcript-aware Poisson GLM) peak calling, optional MACS3 broad-peak cross-check, DRACH motif confirmation as a sanity check (NOT a per-peak filter), exomePeak2 differential calling via the four-BAM-vector interface (bam_ip + bam_input control; bam_treated_ip + bam_treated_input treatment), ChIPseeker annotation, and the canonical Guitar metagene with stop-codon enrichment as the biological QC anchor. Use when running a complete MeRIP analysis from raw reads, when chaining the constituent epitranscriptomics skills (merip-preprocessing -> m6a-peak-calling -> m6a-differential -> modification-visualization), or when wrapping the pipeline in Snakemake / Nextflow.

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Scaffold a minimal GNOME-compliant GTK4/libadwaita app from scratch — window, header bar, ViewSwitcher, adaptive breakpoint, menu, preferences, GSettings schema, desktop entry, meson. Use when starting a new GNOME app or when the user asks for a GNOME app template.

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Responsive GNOME layouts: AdwBreakpoint conditions, BreakpointBin, MultiLayoutView, BottomSheet, narrow/wide layout swaps. Use when making an app work on phones or narrow windows.

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Plan, implement, or improve an internationalization and localization strategy for UI content, formatting, and regional adaptation. Use when the user asks to add i18n, localize, translate, support multiple languages, handle regional formats, manage locale switching, or build a multilingual product.

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Walk through the devnet → mainnet deployment checklist for a Soroban contract or Stellar dApp. Use when a user says "deploy to Stellar mainnet", "going live on Stellar", "deploy my Soroban contract", "Stellar production deployment", "mainnet checklist", or "ship it on Stellar". Covers pre-deployment verification, deployment mechanics with stellar CLI, and post-deployment monitoring with Soroban-specific gates.

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Build AI tutoring systems with adaptive learning. TRIGGERS - Use when user needs help with ai-education-tutor related tasks.

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Windows アプリ開発 (DirectX / WinRT メディア) のグラフィックス・メディア API リファレンス。 Direct2D (ID2D1Factory, ID2D1DeviceContext, ID2D1Bitmap1, ID2D1Effect, D2D1 Effects, ID2D1PathGeometry), DirectWrite (IDWriteFactory, IDWriteTextLayout, DWriteCore), Direct3D 11/12 (D3D11CreateDevice, D3D11On12, DXGI SwapChain, HLSL, D3D12 PipelineState, D3D12 DRED), Microsoft.UI.Composition (Compositor, Visual, ExpressionAnimation, InteractionTracker, MicaController), カメラ・画面キャプチャ (MediaCapture, MediaFrameReader, GraphicsCaptureSession, Windows Studio Effects, OpenCV)、音声・動画再生 (MediaPlayer, MediaPlaybackSession, AudioGraph, MediaTranscoder, AdaptiveMediaSource, HLS, DASH, CastingDevicePicker, AudioPlaybackConnection)。

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nuqs (Type-safe URL search params 状態管理, React / Next.js) リファレンス。 useQueryState, useQueryStates, parseAsString / parseAsInteger / parseAsArrayOf 等 parsers、 NuqsAdapter (Next.js / React Router / TanStack Router / Remix)、createSerializer、 createStandardSchemaV1, inferParserType、shallow routing、history 制御、SSR、 URL 長さ制限 (limits)、Zod / Effect / Sury 連携。

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Claude API (platform.claude.com) の Messages API リファレンス。 streaming (SSE), thinking (adaptive) / preserved thinking / effort, prompt caching, context editing, compaction (on-demand / threshold), structured outputs, Message Batches, token counting, vision / PDF, Files API, citations, embeddings (Voyage AI), errors, rate limits, beta headers, Bedrock / Vertex AI / Foundry 経由アクセス。

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UIKit iOS/iPadOS UI フレームワーク。 UIViewController, UINavigationController, UITabBarController, UISplitViewController, UIView, UILabel, UIButton, UITextField, UIScrollView, UIStackView, UITableView, UICollectionView, diffable data source, NSDiffableDataSourceSnapshot, UICollectionViewCompositionalLayout, Auto Layout, NSLayoutConstraint, NSLayoutAnchor, UILayoutGuide, intrinsicContentSize。 UIArrangementViewController, UISplitArrangement, UIOverlayArrangement, UIView.ReservedRegion, UIHingeInteraction, 縦軸バー, iPhone Duo adaptive layout (iOS 27.1+), scene-based life cycle 移行, UISceneAccessory。SwiftUI ArrangementView とは別 API。

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The live fieldwork layer for psycho-logic — go look at the actual target market NOW instead of reasoning from your training-data stereotype of it. Use when a psycho-logic move needs grounding in a specific place: the user asks 'what do competitors in [region/country] actually do', 'what's the real price band / norm here', 'how do local leaders position themselves', 'research this market before we localise', 'what signals trust to buyers in X', or is about to launch/adapt in a market you haven't studied. Runs structured web research in the local language — local competitors and their signals, price bands, category conventions, review/trust sources, local terminology, taboos and regulations — and synthesises a compact perception profile the four moves consume. Inspired by Rory Sutherland's *Alchemy*. Routed to from psycho-logic; pair with cultural-context (the lens that tells you what to look for). 日本語・中文の相談（「現地の実態を調べて」「调研当地市场」）にも使う。

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The perception-by-culture lens for psycho-logic — establish HOW a specific region, country, or subculture reads a signal before you send it, because perception is culturally coded and the same move can mean the opposite elsewhere. Use when adapting a product, price, message, or campaign to a new market; when the user asks 'will this work in [country/region]', 'why does this land in X but flop in Y', 'how do people here perceive Z', 'how do we localise/differentiate by region', or is about to copy a US/global playbook into another market. Covers the cultural dimensions that move Sutherland's levers — uncertainty avoidance, individualism/collectivism, status/power distance, high- vs low-context communication, mental-accounting norms, trust locus, and taboo/sacredness — and how each rewires reframing, costly-signaling, and experience-design. Inspired by Rory Sutherland's *Alchemy*. Routed to from psycho-logic; pair with market-recon for live local data. 日本語・中文の相談（「この地域で通用する？」「适合本地市场吗？」）にも使う。

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Draft and quality-check pages for the IPA Knowledge Hub in the site's house style. Use when creating a new .qmd Hub page from source material, adapting outside content into a Hub page, or reviewing an existing page for structure, tone, frontmatter, references, and Diátaxis fit. Replicates the quality-control workflow of IPA's Knowledge Hub Generator assistant.

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Assembles genomes de novo from noisy long reads (Oxford Nanopore R9/R10/Dorado, PacBio CLR) with Flye (repeat graph), Canu (correct-trim-assemble OLC), NextDenovo, Shasta, Raven, wtdbg2, or miniasm, and reconciles bacterial assemblies into a consensus with Trycycler/Autocycler. Covers matching the input flag to the basecaller era (--nano-hq vs --nano-raw), why a raw long-read assembly is contiguous but low-QV and not finished until polished, haplotig false-duplication and purge_dups, coverage and read-N50 as non-substitutable inputs, and mid-read adapter de-chimerization. Use when assembling a bacterial or eukaryotic genome from ONT or PacBio noisy reads, choosing a long-read assembler, or diagnosing an over-collapsed or duplicated assembly. For PacBio HiFi use hifi-assembly instead.

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Detects and removes contamination in genome assemblies via two disjoint workflows - foreign-sequence screening of a single-organism (eukaryote/isolate) assembly with NCBI FCS-GX (GenBank-submission-mandatory), FCS-adaptor, and BlobToolKit blob plots; and MAG/bin quality assessment with CheckM2 plus GUNC (chimerism) plus GTDB-Tk taxonomy, judged against MIMAG. Covers why CheckM2 alone is blind to disjoint-marker chimeras, the FCS-GX RAM wall, organelle/NUMT triage, strain heterogeneity, and the HGT-vs-contamination (tardigrade) trap. Use when screening an assembly for foreign contamination before GenBank submission, assessing MAG completeness/contamination/chimerism, deciding which contigs to remove, or distinguishing real HGT from contaminant contigs.

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Detect positive (diversifying / episodic / pervasive) selection using codon dN/dS frameworks. Implements PAML codeml site models (M0/M1a/M2a/M7/M8/M8a), branch models, branch-site model A (Zhang 2005), and HyPhy methods (BUSTED, BUSTED-S, BUSTED-MH, BUSTED-PH, MEME, FEL, FUBAR, aBSREL, SLAC, RELAX, GARD, FUBAR-MH). Includes McDonald-Kreitman framework (asymptotic alpha, impMKT, polyDFE, DFE-alpha, GRAPES) for within-species + divergence inference, RERconverge for trait-correlated rate shifts, CSUBST for convergent substitution, and PhyloAcc for accelerated noncoding evolution. Use when testing adaptive evolution at codons, branches, or full gene; running GARD recombination pre-screen; controlling alignment-error and gBGC false positives; reconciling PAML vs HyPhy results; or performing genome-scale selection scans.

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