151건 · 관련도순
Transform GWAS signals into drug targets and repurposing opportunities. Connects GWAS-significant loci to causal genes via fine-mapping/eQTL, then to druggable proteins via DGIdb/OpenTargets, then to existing drugs via ChEMBL. Use for GWAS-to-target hypothesis generation, druggable-fraction analysis of disease loci, and human-genetics-validated drug-repurposing prioritization.
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AI が生成した日本語テキストから「AI っぽさ」を取り除き、人間が書いた文章に書き換える。 日本語の文章を編集・推敲・レビューするときに使う。Wikipedia の "Signs of AI writing" を 基にした blader/humanizer の日本語版。英語固有のルールは日本語の等価パターンへ置き換え、 日本語特有のパターン（「することができます」の冗長形、敬語の均一化、主語の過剰明示、 カタカナ語の氾濫、定型評価語、体温のない結論、体言止めの乱発）を追加している。
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Build Manhattan, Miami, QQ, and locuszoom-style regional plots from GWAS, TWAS, PWAS, and QTL summary statistics with correct genomic-inflation diagnostics, multi-trait overlays, lead-SNP labeling, and LD-aware regional rendering. Use when visualizing association results across the genome, comparing two traits, computing genomic inflation lambda, or zooming into a locus with LD coloring.
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Performs gene-level association from GWAS summary statistics via genetically predicted tissue expression using FUSION, PrediXcan, S-PrediXcan, S-MultiXcan, UTMOST, MOSTWAS, kTWAS, EpiXcan, TIGAR-V2, and probabilistic fine-mapping with FOCUS and MA-FOCUS. Use when running TWAS from GWAS sumstats, prioritising candidate causal genes from a GWAS lead locus, picking single-tissue vs cross-tissue models, identifying LD-induced TWAS false positives, choosing ancestry-matched prediction weights, fine-mapping co-regulated TWAS hits, or triangulating TWAS with cis-eQTL Mendelian randomization and colocalization to nominate a causal gene.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
Build Manhattan, Miami, QQ, and locuszoom-style regional plots from GWAS, TWAS, PWAS, and QTL summary statistics with correct genomic-inflation diagnostics, multi-trait overlays, lead-SNP labeling, and LD-aware regional rendering. Use when visualizing association results across the genome, comparing two traits, computing genomic inflation lambda, or zooming into a locus with LD coloring.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
Performs gene-level association from GWAS summary statistics via genetically predicted tissue expression using FUSION, PrediXcan, S-PrediXcan, S-MultiXcan, UTMOST, MOSTWAS, kTWAS, EpiXcan, TIGAR-V2, and probabilistic fine-mapping with FOCUS and MA-FOCUS. Use when running TWAS from GWAS sumstats, prioritising candidate causal genes from a GWAS lead locus, picking single-tissue vs cross-tissue models, identifying LD-induced TWAS false positives, choosing ancestry-matched prediction weights, fine-mapping co-regulated TWAS hits, or triangulating TWAS with cis-eQTL Mendelian randomization and colocalization to nominate a causal gene.
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IoT and embedded device security testing methodology. Covers hardware reconnaissance (UART, JTAG, SWD, SPI flash, I2C EEPROM, eMMC chip-off), firmware acquisition (vendor portals, OTA capture, flash dump, binwalk extraction), firmware analysis (filesystem mounting, binary triage, hardcoded secrets, default credential discovery), bootloader attacks (U-Boot console, secure-boot bypass, fault injection), runtime attacks on embedded Linux/RTOS (busybox CVEs, MTD writes, /dev/mem), wireless protocol attacks (Zigbee, BLE, Z-Wave, LoRaWAN, Thread/Matter, sub-GHz), MQTT/CoAP/Modbus/BACnet/OPC-UA exploitation, mobile companion app analysis, cloud-IoT API abuse, and side-channel/glitching basics. Use for IoT pentest, smart-home assessment, ICS/OT testing, or embedded vulnerability research.
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