2.1천건 · 관련도순
Fine-tune LLMs using reinforcement learning with TRL - SFT for instruction tuning, DPO for preference alignment, PPO/GRPO for reward optimization, and reward model training. Use when need RLHF, align model with preferences, or train from human feedback. Works with HuggingFace Transformers.
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Runs and configures curated nf-core community Nextflow pipelines (rnaseq, sarek, atacseq, methylseq, ampliseq, taxprofiler, fetchngs) reproducibly, pinning the pipeline revision with -r and selecting a container engine and institutional config via -profile. Use when deciding to adopt a community pipeline versus author one from scratch; picking a pipeline and pinning its -r revision; selecting -profile test/docker/singularity/conda plus an institutional config from nf-core/configs; building and validating a samplesheet CSV against the pipeline schema (nf-schema); choosing --genome/iGenomes versus custom references; configuring resources and max_memory for SLURM/AWS Batch; using -resume and -stub; and reading MultiQC outputs.
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Orchestrate the full ToolUniverse self-improvement cycle: discover APIs, create tools, test with researcher personas, fix issues, optimize skills, and push via git. References and dispatches to all other devtu skills. Use when asked to: run the self-improvement loop, do a debug/test round, expand tool coverage, improve tool quality, or evolve ToolUniverse.
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Dereplicate a putative natural product and assign its chemical taxonomy. Use to answer "is [compound] a known natural product", "what microbe/organism produces [compound]", "what chemical class is [compound]", "dereplicate this metabolite (by formula/exact mass/InChIKey/SMILES)", or "classify this molecule into ChemOnt". Searches NPAtlas for known microbial natural products (producing organism + literature reference), assigns the ChemOnt kingdom→superclass→class→subclass hierarchy via ClassyFire, resolves systematic IUPAC names to structure via OPSIN, and cross-references identity in PubChem. NOT for general drug/compound identity or ADMET (use tooluniverse-chemical-compound-retrieval / tooluniverse-small-molecule-discovery) and NOT for metabolomics pathway/enrichment analysis (use tooluniverse-metabolomics skills).
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Generates 3D conformer ensembles using RDKit ETKDGv3 with knowledge-enhanced distance geometry, MMFF94/UFF force-field optimization, CREST + GFN2-xTB semi-empirical refinement, and macrocycle-aware torsion preferences. Provides explicit decision rules for single vs ensemble conformer use, RMSD pruning, energy windows, conformer count, and force-field choice. Use when preparing 3D ligands for docking, generating descriptor input for 3D QSAR, or sampling macrocycle/peptide conformational ensembles.
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Exclusive-choice UI: CheckButton radio groups in list rows, when to use them vs ComboRow vs ToggleGroup. Use when presenting mutually exclusive options in GNOME preferences or dialogs.
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Scaffold a minimal GNOME-compliant GTK4/libadwaita app from scratch — window, header bar, ViewSwitcher, adaptive breakpoint, menu, preferences, GSettings schema, desktop entry, meson. Use when starting a new GNOME app or when the user asks for a GNOME app template.
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Use to process automated PR review feedback (Copilot, Greptile, Codex) and iterate until all AI threads are addressed, checks are green, and the PR is merge-ready. Trigger when the user says "address review feedback", "recycle reviews", or references an automated reviewer.
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Surface current and recent Stellar Community Fund (SCF) round activity. Use when a user says "current SCF round", "what's happening with SCF", "active SCF submissions", "should I apply to SCF this round", "SCF deadline", "who is applying to SCF right now", "SCF round status", or "show me this round's submissions". Fetches live data from communityfund.stellar.org and cross-references with the LumenLoop ecosystem DB to flag repeat builders and category trends.
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Stellar standards, ecosystem, and reference. Covers SEPs (Stellar Ecosystem Proposals), CAPs (Core Advancement Proposals), and a quick map for picking the right standard for wallets, anchors, payments, deposits/withdrawals, federation, deep links, and KYC. Also bundles ecosystem references (DeFi protocols, dev tools, wallets, infra, community projects), curated documentation links, and MCP servers (live tools such as Raven). Use when you need to know which SEP applies, or want a starting point for ecosystem integrations, official docs, or live MCP tooling.
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Roslyn-powered semantic query CLI for C# solutions. Use when you need to find references, callers, implementations, dependencies, members, or trace call chains in a C# codebase — replaces multi-round grep/read cycles with single precise queries.
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Auto-detect project tech stack and generate stack-specific references for domain skills
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Check documentation references, sync docs to code changes, and detect translation drift. Use for documentation maintenance in a repository.
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Extract applicant details, employment history, income, and references from a rental application form into structured JSON for tenant screening.
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Extract shipper, consignee, order references, carton lines, weights, and package totals from packing lists.
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Extract company information, submitted identity-document references, and beneficial ownership data from onboarding packets.
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Extract carrier invoice, shipment references, rates, accessorials, taxes, and total charges from freight bills.
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Extract timekeeper entries, disbursements, matter references, and billing summaries from law firm invoices.
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Generate ideas that don't sound logical, then validate them with cheap behavioural experiments — Rory Sutherland's 'the opposite of a good idea can be a good idea' plus revealed-preference testing. Use when the obvious/logical solution is saturated and the user wants genuinely different options, asks 'what's a creative/unconventional angle', 'how do we stand out', 'should we run a test/experiment', 'how do we know what people actually want', or is about to trust a survey/focus group. Covers deliberate inversion of the obvious move, why stated preferences lie, and designing small reversible experiments that watch behaviour. Inspired by Rory Sutherland's *Alchemy*. Routed to from psycho-logic. 日本語の相談（「競合と同じ案しか出ない」「アンケートは好評なのに売れない」「思い切った案を安く試したい」）にも使う。中文咨询（“只能想出和竞品一样的方案”“问卷好评却卖不动”）也适用。
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Word文書（.docx）をMarkdownに変換し、参考文献を整理するスキル。「Wordをマークダウンに変換して」「docxをmdに変換して参考文献を整理して」「Word文書の参考文献を統合して」「レポートをMarkdownに変換して」などのリクエスト時に使用。pandoc（またはpython-docxフォールバック）による変換と、重複URL統合・番号再割当て・参考文献リスト生成・文書構造整形を行う。
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Create an aggregated Epic PR from a `cc-epic-<Issue number>` branch to the default branch. Takes the Epic Issue number as argument, assumes sub-PRs have already been merged into the epic branch, and automatically generates the PR title and description from the commit log against the base branch (including sub-PR / sub-Issue references). The PR is posted via `gh pr create` with no label and `Closes #<Epic Issue>`.
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Survey related literature for a research topic or paper draft. Finds relevant papers, identifies citation gaps, and suggests key references. Use for "find related work", "survey papers on X", "what papers should I cite". 旧名 survey-literature。
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Use when the user is explicitly working with Quarto, .qmd files, _quarto.yml, Quarto projects, or Quarto features such as callouts, cross-references, citations, Mermaid diagrams, extensions, websites, books, presentations, and reports. Also use for explicit migration from or comparison with R Markdown, bookdown, blogdown, xaringan, distill, or Jupyter notebooks to Quarto. Do not use for general R Markdown or related-format questions unless Quarto or migration to Quarto is explicitly mentioned.
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Draft and quality-check pages for the IPA Knowledge Hub in the site's house style. Use when creating a new .qmd Hub page from source material, adapting outside content into a Hub page, or reviewing an existing page for structure, tone, frontmatter, references, and Diátaxis fit. Replicates the quality-control workflow of IPA's Knowledge Hub Generator assistant.
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