'spr' 검색 결과

Publish, deactivate, and delete AEM content programmatically via the Cloud Service Replication API (com.day.cq.replication). Covers single-path and bulk activation, preview-tier targeting with AgentFilter, synchronous/async options, ReplicationStatus checks, permission validation, workflow process steps, and replication event handling. Use when the user needs to publish pages, activate or deactivate content, check replication status, build workflow steps that replicate content, listen to replication events, query batch publication state, or work with Replicator, ReplicationOptions, or ReplicationStatusProvider in AEM Cloud Service.

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Audit and update metadata across multiple AEM Edge Delivery Services pages. Scans pages via the query index, identifies missing or inconsistent metadata (titles, descriptions, og tags, robots), and generates a corrected bulk metadata spreadsheet. Use when standardizing metadata across a site, preparing for launch, or fixing SEO issues at scale.

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Apple's approach to interface design and fluid, physical motion, translated for the web. Use when building or reviewing gesture-driven UI, spring animations, drag/swipe/sheet interactions, momentum and interruptible transitions, translucent materials and depth, typography (optical sizing, tracking, leading), reduced-motion, or the design foundations (feedback, spatial consistency, restraint) behind Apple-style interfaces.

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UI 資產委託導演 SKILL — 讀取 family-map 與 skin-family-*.json，產生 asset-task-manifest / param-tune-manifest 與精確 ArtRecipe，列出每個 family slot 所需的 spriteFrame 路徑、尺寸規格、9-slice 邊距。USE FOR: family-architect 輸出 asset-pending 狀態後，正式產出 UCUF partial asset 任務。DO NOT USE FOR: 非 UI 資產生成、程式邏輯開發、QA 驗證（用 ui-asset-qc）。

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Idiomatic Go - package and interface design, error wrapping, table-driven tests, generics, the modern standard library (slices/maps/cmp/errors.Join), current syntax, and logging discipline. Use when writing, reviewing, or refactoring any Go code, especially code drifting toward Java/Spring shapes (deep layer trees, generic repositories, heavy frameworks) - even if the user never says "idiomatic". Distilled from spf13/go-skills and adapted to this repo.

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Find the right skill for a capability. Load when a user or skill needs to check if a skill exists for a given task, when process-decomposer assigns skills to steps, or when agent-builder checks skill availability. Triggers on "what skill does this need", "find a skill for", "is there a skill that", "which skill handles", "does a skill exist for", "skill lookup", "check skill library". Prevents skill sprawl by always checking existing skills before creating new ones. The gatekeeper for all skill creation.

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Audit the project's technical health and identify "high-interest" debt. Load when the user asks to check code quality, find TODOs, assess project health, or prepare for a refactoring sprint. Also triggers on "technical debt audit", "where is the code messy", "assess project health", "find my hacks", or "identify tech debt". Essential for maintaining velocity in growing projects.

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Critically audit agent skills and remove content that is outdated, disproven, model-specific, or based on poorly cited sources. Load when improve-skills runs its per-skill cycle, when the user asks to prune skills, remove outdated techniques, check if skills are still valid, verify citations in skills, audit skill sources, or update skills for a new model release. Also triggers on "are these skills still valid", "check for obsolete techniques", "verify skill citations", or "update skills for GPT-5/Claude 4/Gemini 2". Runs before split-skill and compress-skill — removing bad content first means the remaining content is worth preserving.

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Apple's approach to interface design and fluid, physical motion, translated for the web. Use when building or reviewing gesture-driven UI, spring animations, drag/swipe/sheet interactions, momentum and interruptible transitions, translucent materials and depth, typography (optical sizing, tracking, leading), reduced-motion, or the design foundations (feedback, spatial consistency, restraint) behind Apple-style interfaces.

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Picks random winners from lists, spreadsheets, or Google Sheets for giveaways, raffles, and contests. Ensures fair, unbiased selection with transparency.

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Generate PPTX presentations, DOCX documents, XLSX spreadsheets, and PDF reports from structured JSON input using PaperJSX.

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Corrects fluorophore spillover (conventional compensation) or spectral overlap (spectral unmixing) and applies variance-stabilizing transforms (logicle/biexponential, arcsinh, log) for flow and mass cytometry. Covers spillover-matrix estimation from single-stain controls, AutoSpill, the spillover spreading matrix and why panel design (not compensation) bounds resolution, compensate-then-transform ordering, and arcsinh cofactor choice (5 for CyTOF, ~150 for fluorescence, per-channel via flowVS). Use when correcting spectral overlap, preparing data for gating/clustering, choosing logicle vs arcsinh, deciding a cofactor, or distinguishing compensation from spectral unmixing.

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Retrieve records from NCBI databases using Biopython Bio.Entrez (EFetch, ESummary). Use when downloading sequences, fetching GenBank/GenPept records, getting document summaries, parsing nested XML, navigating GI deprecation, choosing between rettype+retmode combinations, and parsing into Biopython SeqRecord/SwissProt objects. Covers nucleotide, protein, gene, pubmed, sra, gds, taxonomy, snp, clinvar.

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Run remote BLAST searches against NCBI servers using Biopython Bio.Blast.NCBIWWW. Use when identifying unknown sequences, finding homologs, picking the correct BLAST program (blastn/blastp/blastx/tblastn/tblastx/psiblast/megablast/dc-megablast), interpreting Karlin-Altschul E-values, avoiding the max_target_seqs trap (Shah 2019), choosing composition-based statistics, or limiting searches by organism. Covers RID lifecycle, database choice (nt/nr/refseq_select/swissprot), word-size and CBS taxonomy.

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Build sequence logos from aligned DNA, RNA, or protein motifs using ggseqlogo (R), Logomaker (Python), or WebLogo with explicit bits vs probability encoding, background-frequency correction, custom alphabets, and multi-logo stacking. Use when visualizing motif PWMs (TF binding, splice sites, CRISPR spacers), aligned-position composition, or comparing two motif sets.

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Detect introgression and admixture between species or populations using Dsuite (Malinsky 2021 fast D-statistics), Patterson's D / ABBA-BABA test (Green 2010; Durand 2011), f4-ratio and f-branch statistic (Malinsky 2018), TreeMix (Pickrell & Pritchard 2012), HyDe (Blischak 2018), QuIBL (Edelman 2019), sprime (Browning 2018), Twisst (Martin 2017), PhyloNet (Solis-Lemus 2017) for explicit phylogenetic networks, and qpAdm / qpGraph (Patterson 2012; Lipson 2013). Distinguish introgression from incomplete lineage sorting (ILS), ancestral structure, ghost-lineage admixture, and rate variation. Use when testing inter-species gene flow, dating admixture events, identifying introgressed segments, building phylogenetic networks for reticulate evolution, or applying the ABBAclustering (Koppetsch-Malinsky-Matschiner 2024) framework for divergent-species gene flow.

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Builds QSAR / QSPR models using chemprop D-MPNN, MolFormer, Uni-Mol, ChemBERTa, random forest baselines, and Gaussian processes with explicit handling of OECD 5 principles, applicability domain (kNN, leverage, conformal prediction, Mahalanobis), scaffold-balanced splits, ensemble uncertainty, calibration (Platt, isotonic), feature importance (SHAP, atomic attribution), and prospective validation. Use when building target-specific predictive models from in-house bioassay data, ADMET endpoints, or selectivity profiles.

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Predict enhancer-gene regulatory connections from ATAC-seq using ABC, ENCODE-rE2G, HiChIP, or Cicero. Use when linking distal enhancers to target genes, choosing between contact-aware (ABC, ENCODE-rE2G), accessibility-only (Cicero), and orthogonal (HiChIP H3K27ac, EpiMap) approaches, validating predictions against CRISPRi-FlowFISH gold-standard, or building cell-type-specific regulatory maps for fine-mapping or therapeutic target discovery.

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Predicts whether a DNA variant alters mRNA splicing using sequence-based deep-learning tools — SpliceAI (10kb context dilated CNN, clinical default), Pangolin (multi-tissue), MMSplice (modular per-region CNN with calibrated ΔPSI), SpliceTransformer/TrASPr (tissue-aware transformers), SpliceVault (empirical 300K-RNA lookup of likely mis-splicing outcomes), CADD-Splice (composite score). Applies the ClinGen SVI 2023 framework for ACMG/AMP variant interpretation (PVS1, PP3, BP4 evidence codes), HGVS splicing nomenclature (c.123+1G>A, c.123-3T>G, r.spl?), extended-window scoring for deep-intronic pseudoexons, tissue-specific predictions, branchpoint variant detection (BPHunter, LaBranchoR), and splice-switching ASO design. Use when interpreting splice impact of clinical variants, prioritizing VUS, identifying deep-intronic pathogenic variants, or designing ASOs.

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Use when a carrier or driver asks about winter trucking, snow chain requirements, hot-weather precautions, summer tire failures, fuel additive use (anti-gel), idle management in extreme temperatures, weight restrictions in spring thaw, or how seasonal demand patterns affect freight rates and capacity.

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Collage as a web design aesthetic — overlapping elements, mixed media, cut-out shapes, scrapbook layouts, and editorial magazine spreads adapted for the web. CSS techniques for layered compositions using z-index stacking, clip-path, mix-blend-mode, parallax layering, and grid-breaking layouts. Activate on 'collage web', 'editorial layout', 'magazine layout', 'overlapping elements', 'scrapbook', 'cut-out aesthetic', 'mixed media web', 'layered composition', 'grid-breaking', 'editorial web design', 'fashion website layout', 'David Carson'. NOT for photo collage/gallery grids (use collage-layout-expert), maximalist density (use maximalist-web-design), neobrutalism (use neobrutalist-web-designer).

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Design and build mathematically rigorous, high-density, interactive data graphics and streaming telemetry visualizations following Mike Bostock's D3.js and Observable methodologies. Use when crafting custom SVG/Canvas charts, reactive streaming time-series, multi-dimensional brush-and-link coordinates, small multiples, or topological swarm graphs. NOT for generic dashboard template clones, basic spreadsheet charts, or off-the-shelf low-effort wrapper libraries.

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Checks whether a story is ready to implement: clear acceptance criteria, no open questions, valid ADR and dependencies. Use when the user asks if a story, or the sprint's stories, are ready to start or build.

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Scaffold the test framework and CI — tests/ directory, engine test runner, GitHub Actions workflow. Once, before the first sprint.

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