'bulk' 검색 결과

Parallel map-reduce bulk ingest for large source sets. Map phase dispatches read-only knowledge-extractor agents (≤N-wide, default Haiku) emitting per-source JSON extracts; Python routes extracts by target library file (fuzzy-merging new topics, pre-allocating new files, flagging oversized topics); reduce phase dispatches one agent-knowledge-updater per file (parallel, one writer per file); single shelf-index rebuild + one log.md entry. Resumable. Supersedes kb-ingest-batch.

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Build with Aurora DSQL — manage schemas, execute queries, handle migrations, diagnose query plans, load data, and develop applications with a serverless, distributed SQL database. Covers IAM auth, multi-tenant patterns, MySQL-to-DSQL and PostgreSQL-to-DSQL schema conversion, FK replacement code generation, OCC retry patterns, ORM migration (Django/Hibernate/Rails), DDL operations, query plan explainability, SQL compatibility validation, and bulk data loading. Triggers on phrases like: DSQL, Aurora DSQL, distributed SQL database, serverless PostgreSQL-compatible database, migrate to DSQL, DSQL query plan, DSQL EXPLAIN ANALYZE, DSQL ENUM, DSQL foreign key, DSQL OCC retry, DSQL multi-region, DSQL JSONB, DSQL GIN index, load into DSQL, load CSV into DSQL, bulk load DSQL, aurora-dsql-loader.

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Use when sending transactional emails (welcome messages, order confirmations, password resets, receipts), notifications, or bulk emails via Resend API. Triggers on "send email", "transactional email", "welcome email", "Resend API", "password reset email", "order confirmation", "receipt email", "notification email", "bulk email send".

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Bulk RNA-seq differential expression — experimental design, count modeling with DESeq2/edgeR, and enrichment.

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Focused single-target audit of one Gaia skill, named skill, or real-skill catalog item. Use this skill when: auditing a specific skill by ID or name, a skill looks overpromoted, evidence feels thin or dead, a contributor's skill seems outdated or superseded, the rank doesn't match the source quality, evidence is mapped to the wrong Evidence Type, a skill at 3★+ is missing a working GitHub link, someone asks "does this skill deserve its stars?", or you want the smallest possible correction with validation — not a bulk sweep. This is NOT for bulk curation passes (use /gaia-curate for that) or meta-level registry sweeps (use /gaia-meta-audit). It is specifically for "fix this one skill, get it right."

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Find and work with ENCODE single-cell genomics data including scRNA-seq and scATAC-seq. Use when the user asks about single-cell experiments, cell type resolution, clustering from ENCODE data, deconvolution of bulk signals using single-cell references, or comparing single-cell vs bulk profiles. Covers platform differences (10X Chromium, Smart-seq2, Drop-seq), quality limitations of single-cell data, multimodal integration (RNA+ATAC), and cross-study reproducibility concerns. Also use for cell type annotation, gene detection limits, dropout artifacts, and single-cell data structure in ENCODE.

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Guide for integrating CellxGene Census single-cell data with ENCODE bulk experiments. Use when users need cell-type-specific expression context for ENCODE regulatory data, want to deconvolve bulk ENCODE signals, or validate regulatory elements at single-cell resolution. Trigger on: CellxGene, single-cell atlas, cell type expression, Census, cell type specificity, single-cell context, scRNA-seq atlas.

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Use this skill to create, deactivate, freeze, or manage Salesforce users, assign user licenses and feature licenses, configure profiles and roles, set login hours and IP restrictions, and set up delegated administration. Triggers: 'add a new user in Salesforce', 'create a user and assign a licence', adding a new user, deactivating a departing employee, license assignment, freezing a user account, delegated admin setup. NOT for designing the permission set / PSG model — use admin/permission-set-architecture. NOT for who can see which records — use admin/sharing-and-visibility. Also covers: bulk user loads by CSV, Bulk API 2.0 upsert on Username, the UserLogin freeze object, licence and permission-set-licence reclamation, Role metadata deployment, and the offboarding checklist as SOQL.

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Use when designing or refactoring record types across objects with many profiles, business processes, or picklist variations. Covers layout assignment explosion, Dynamic Forms migration, and record type ID portability. NOT for basic record type setup or page layout assignment — use admin/record-types-and-page-layouts. NOT for converting one page layout to Dynamic Forms — use admin/dynamic-forms-migration. Trigger keywords: record type consolidation, layout assignment matrix, recordTypeVisibilities, layoutAssignments, Master record type default, bulk RecordTypeId migration, record type audit, RecordType wildcard package.xml.

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Use this skill to select the right Salesforce integration pattern — from point-to-point to event-driven to hub-and-spoke — by applying the official Salesforce two-axis decision framework (integration type × timing) to a business integration scenario. Trigger keywords: integration pattern decision, choose integration approach, Salesforce integration architecture, when to use platform events vs API, integration type selection. NOT for implementation of any specific integration pattern (use domain-specific integration skills), MuleSoft architecture (use architect/mulesoft-anypoint-architecture), or middleware vendor selection. More triggers: integration decision record, Bulk API vs REST for a nightly load, external Id upsert, Named Credential vs Remote Site Setting, platform event vs CDC, who calls whom.

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Router for the 61 SfSkills `integration` skill packages. INBOUND integration and the API surface itself: the Salesforce REST and SOAP APIs, Bulk API 2.0 jobs, Platform Events, CDC, Pub/Sub, Named Credentials and middleware. For calling OUT to someone else's API from Apex, use salesforce-apex instead. Use when the request mentions integration, Salesforce REST API, composite API, SOAP API, Bulk API 2.0 job, Platform Event, Change Data Capture, Pub/Sub, inbound webhook, Named Credential, OAuth, connected app, MuleSoft, Salesforce Connect, external system calling Salesforce. Finds and opens the exact skill package to read; it does not contain the guidance itself.

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Router for the 101 SfSkills `data` skill packages. Data model, data movement and data quality: migrations, bulk loads, query optimisation, deduplicating at volume, archival. Ordinary-volume duplicate cleanup and prevention use salesforce-admin; come here for hundreds-of-thousands+ dedup or third-party tools. LDV architecture uses salesforce-architect. Use when the request mentions data model, data migration, data load, Data Loader, Bulk API, external id, deduplication at volume, archival, SOSL, cross-object search, sandbox seed data, SandboxPostCopy, native Data Seeding. Finds and opens the exact skill package to read; it does not contain the guidance itself.

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Task and Event objects: polymorphic WhatId/WhoId, Activity object model, ActivityHistory vs OpenActivity, activity timeline customization, bulk task creation, Einstein Activity Capture boundaries. NOT for turning on EAC or calendar sync — use admin/einstein-activity-capture-setup. NOT for Email-to-Case — use admin/case-management-setup. Covers ActivitiesSettings metadata, enableActivities, shared Task/Event custom fields and FLS, TaskStatus value sets, Shared Activities and TaskRelation/EventRelation, recurring and child activities, and partial-success bulk DML on Task.

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Router for the 63 SfSkills `flow` skill packages. Flow Builder: record-triggered, screen, scheduled and orchestration flows, bulkification, fault handling, limits, testing. "My flow" belongs here even when salesforce-apex also names the limit. Nightly scheduling without naming code defaults here; apex takes it when code/class/Apex is named. Flow-vs-Apex choice before anything is built: admin/process-automation-selection. Use when the request mentions Flow, Flow Builder, record-triggered flow, screen flow, scheduled flow, subflow, fault path, flow element, orchestration, Process Builder migration, Workflow Rule migration, flow limit, flow hitting SOQL limit, too many SOQL queries in a flow, flow bulkification, Get Records performance. Finds and opens the exact skill package to read; it does not contain the guidance itself.

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Infer gene regulatory networks from bulk or general expression data with mutual-information (ARACNe) and tree-ensemble (GENIE3, GRNBoost2) methods, and infer transcription-factor protein activity from regulons with VIPER and msVIPER. Covers the activity-not-edges paradigm, the undirected-association caveat, the DREAM5 wisdom-of-crowds and method-complementarity result, AUPRC-over-AUROC evaluation, and gold-standard incompleteness. Use when inferring a regulatory network from a bulk expression matrix, finding master regulators, or scoring TF activity from a signature. For single-cell motif-pruned regulons see scenic-regulons; for co-expression modules see coexpression-networks.

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Stores and operates on sparse expression matrices for single-cell and large bulk RNA-seq, covering dgCMatrix/dgRMatrix/dgTMatrix when-each-is-fast, the dgCMatrix (CSC, R) <-> CSR (Python) implicit transpose, AnnData (cells-rows) <-> SingleCellExperiment (cells-cols) orientation flip, HDF5/h5ad vs Zarr cloud-native shift, HDF5SummarizedExperiment + DelayedArray for out-of-memory bulk, scanpy backed mode for large h5ad, the ~10-15% density crossover where dense beats sparse, 10X format proliferation (MTX vs CellRanger H5 vs h5ad), the dense-conversion memory blow-up, and Dask + Zarr for consortium-scale matrices. Use when choosing sparse format, working with single-cell-sized matrices, importing/exporting 10X, debugging R/Python interop transposes, processing matrices too large for RAM, or building cloud-native pipelines.

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Performs differential expression on bulk RNA-seq count data with edgeR's negative-binomial GLM and quasi-likelihood F-test framework. Covers DGEList construction, filterByExpr, TMM/TMMwsp normalization, robust dispersion estimation, glmQLFit/glmQLFTest, TREAT for magnitude-bounded hypotheses, contrasts via no-intercept designs, voom and voomWithQualityWeights for heterogeneous samples, and the edgeR v4 bias-corrected APL changes. Use when running bulk DE with edgeR, choosing edgeR over DESeq2 (small n, transcript DE via catchSalmon, large samples), needing TREAT for a fold-change-threshold hypothesis, troubleshooting v3-to-v4 reproducibility, building paired or interaction designs, or handling library-quality heterogeneity.

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Handles batch effects in bulk RNA-seq via design-matrix inclusion (the correct path for DE), ComBat/ComBat-seq for visualization, SVA for unknown latent factors, RUVSeq for negative-control-gene-anchored unwanted variation, and limma::removeBatchEffect for plotting only. Encodes the Nygaard 2016 cardinal sin against testing on a batch-corrected matrix, the choice between SVA/RUVg/RUVs/RUVr, the confounding non-identifiability problem, the single-cell boundary (Harmony/MNN are NOT for bulk), and the Goh 2017 harmonization critique. Use when designing a DE analysis with batch structure, troubleshooting batch-dominated PCA, choosing ComBat vs ComBat-seq, handling unknown batch via SVA, integrating across studies, or deciding when (rarely) to subtract batch.

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Performs differential expression on bulk RNA-seq count data with DESeq2's negative-binomial GLM, Wald and LRT testing, apeglm/ashr/normal LFC shrinkage, independent filtering, Cook's outlier handling, VST/rlog transforms, and design formulas including paired, batch, and interaction terms. Use when running bulk DE, choosing DESeq2 over edgeR or limma-voom, building a paired or interaction design, applying LFC shrinkage for ranking or GSEA, choosing Wald vs LRT, troubleshooting padj=NA, picking VST vs rlog, importing salmon/kallisto via tximport, or analyzing prokaryotic RNA-seq.

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Resolve subclonal copy number, whole-genome doubling, and copy-number tumor evolution from bulk sequencing with Battenberg, TITAN, and MEDICC2. Covers clonal versus subclonal copy-number states, haplotype phasing for subclonal resolution, cancer cell fraction, whole-genome-doubling detection and timing relative to mutations, mirrored subclonal allelic imbalance, and copy-number phylogenies. Use when a tumor is heterogeneous and bulk data shows non-integer copy number, when calling subclonal CNAs, detecting or timing whole-genome doubling, reconstructing copy-number evolution, or deciding between Battenberg and TITAN.

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Bulk-query Ensembl BioMart (and other BioMart instances) for cross-database ID mapping, gene/transcript/exon coordinates, and ortholog tables. Use when batch-converting Ensembl IDs to other namespaces (HGNC, RefSeq, UniProt, Entrez), pulling gene coordinate tables for thousands of genes, building ortholog wide-tables across species, or replacing slow Ensembl REST loops with one-shot bulk export. Encodes BioMart's XML query format, R biomaRt vs Python pybiomart trade-off, mart-vs-dataset hierarchy, and the URL endpoint that's BioMart-specific (separate from rest.ensembl.org).

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Bulk JIRA ops (10+ issues): transition/assign/priority/clone/delete via jira-as; dry-run mandatory. NOT single-issue ops (mk:jira-issue, mk:jira-lifecycle).

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JIRA issue CRUD via jira-as. NOT lifecycle (mk:jira-lifecycle), comments (mk:jira-collaborate), bulk (mk:jira-bulk), links (mk:jira-relationships), or time/sprint (mk:jira-time/agile).

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Drive JIRA workflow lifecycle via jira-as: transition, assign, resolve, reopen, versions, components. NOT issue CRUD (mk:jira-issue) or bulk transitions (mk:jira-bulk).

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