'correction' 검색 결과

Batch effect correction for CRISPR screens covering ComBat empirical-Bayes, RUV, SVA, control-sgRNA normalization, and the model-based alternative of including batch as a covariate in MAGeCK MLE or Chronos. Covers screen-specific batch sources (passage cohort, library lot, infection day, sequencing run, Cas9 lot, FBS lot), PCA + variance-decomposition diagnostic to decide if correction is needed, when correction harms biology by over-correcting condition into batch, limma removeBatchEffect for visualization-only correction, and relationship to multi-condition design matrices. Use when combining screens for joint analysis, when passage cohort confounds biology, when DepMap-style panels need Chronos with batch covariates, when picking ComBat vs RUV, or when correction harms biology and should be replaced with explicit covariate modeling.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Batch effect correction for CRISPR screens covering ComBat empirical-Bayes, RUV, SVA, control-sgRNA normalization, and the model-based alternative of including batch as a covariate in MAGeCK MLE or Chronos. Covers screen-specific batch sources (passage cohort, library lot, infection day, sequencing run, Cas9 lot, FBS lot), PCA + variance-decomposition diagnostic to decide if correction is needed, when correction harms biology by over-correcting condition into batch, limma removeBatchEffect for visualization-only correction, and relationship to multi-condition design matrices. Use when combining screens for joint analysis, when passage cohort confounds biology, when DepMap-style panels need Chronos with batch covariates, when picking ComBat vs RUV, or when correction harms biology and should be replaced with explicit covariate modeling.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Batch effect correction for CRISPR screens covering ComBat empirical-Bayes, RUV, SVA, control-sgRNA normalization, and the model-based alternative of including batch as a covariate in MAGeCK MLE or Chronos. Covers screen-specific batch sources (passage cohort, library lot, infection day, sequencing run, Cas9 lot, FBS lot), PCA + variance-decomposition diagnostic to decide if correction is needed, when correction harms biology by over-correcting condition into batch, limma removeBatchEffect for visualization-only correction, and relationship to multi-condition design matrices. Use when combining screens for joint analysis, when passage cohort confounds biology, when DepMap-style panels need Chronos with batch covariates, when picking ComBat vs RUV, or when correction harms biology and should be replaced with explicit covariate modeling.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Batch effect correction for CRISPR screens covering ComBat empirical-Bayes, RUV, SVA, control-sgRNA normalization, and the model-based alternative of including batch as a covariate in MAGeCK MLE or Chronos. Covers screen-specific batch sources (passage cohort, library lot, infection day, sequencing run, Cas9 lot, FBS lot), PCA + variance-decomposition diagnostic to decide if correction is needed, when correction harms biology by over-correcting condition into batch, limma removeBatchEffect for visualization-only correction, and relationship to multi-condition design matrices. Use when combining screens for joint analysis, when passage cohort confounds biology, when DepMap-style panels need Chronos with batch covariates, when picking ComBat vs RUV, or when correction harms biology and should be replaced with explicit covariate modeling.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Batch effect correction for CRISPR screens covering ComBat empirical-Bayes, RUV, SVA, control-sgRNA normalization, and the model-based alternative of including batch as a covariate in MAGeCK MLE or Chronos. Covers screen-specific batch sources (passage cohort, library lot, infection day, sequencing run, Cas9 lot, FBS lot), PCA + variance-decomposition diagnostic to decide if correction is needed, when correction harms biology by over-correcting condition into batch, limma removeBatchEffect for visualization-only correction, and relationship to multi-condition design matrices. Use when combining screens for joint analysis, when passage cohort confounds biology, when DepMap-style panels need Chronos with batch covariates, when picking ComBat vs RUV, or when correction harms biology and should be replaced with explicit covariate modeling.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Designs genomics experiments so technical nuisance variation (batch, lane, plate, flow cell, operator, reagent lot, processing day) is balanced against the biological variable of interest and therefore estimable rather than confounded, using constrained sample-to-batch assignment (designit, OSAT), the confounder/mediator/collider distinction, and the principle that no post-hoc correction recovers a fully confounded design. Covers detecting hidden batches with surrogate variable analysis, a decision table for downstream correction (ComBat-seq, RUVSeq, SVA) whose execution is deferred to differential-expression/batch-correction, and reproducibility metadata. Use when assigning samples to sequencing batches/lanes/plates, avoiding batch-condition confounding, deciding whether a design is salvageable by correction, choosing a correction method, or estimating the number of hidden batches. For the experimental unit, randomization, and blocking concepts see experimental-design/randomization-blocking.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Designs genomics experiments so technical nuisance variation (batch, lane, plate, flow cell, operator, reagent lot, processing day) is balanced against the biological variable of interest and therefore estimable rather than confounded, using constrained sample-to-batch assignment (designit, OSAT), the confounder/mediator/collider distinction, and the principle that no post-hoc correction recovers a fully confounded design. Covers detecting hidden batches with surrogate variable analysis, a decision table for downstream correction (ComBat-seq, RUVSeq, SVA) whose execution is deferred to differential-expression/batch-correction, and reproducibility metadata. Use when assigning samples to sequencing batches/lanes/plates, avoiding batch-condition confounding, deciding whether a design is salvageable by correction, choosing a correction method, or estimating the number of hidden batches. For the experimental unit, randomization, and blocking concepts see experimental-design/randomization-blocking.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Designs genomics experiments so technical nuisance variation (batch, lane, plate, flow cell, operator, reagent lot, processing day) is balanced against the biological variable of interest and therefore estimable rather than confounded, using constrained sample-to-batch assignment (designit, OSAT), the confounder/mediator/collider distinction, and the principle that no post-hoc correction recovers a fully confounded design. Covers detecting hidden batches with surrogate variable analysis, a decision table for downstream correction (ComBat-seq, RUVSeq, SVA) whose execution is deferred to differential-expression/batch-correction, and reproducibility metadata. Use when assigning samples to sequencing batches/lanes/plates, avoiding batch-condition confounding, deciding whether a design is salvageable by correction, choosing a correction method, or estimating the number of hidden batches. For the experimental unit, randomization, and blocking concepts see experimental-design/randomization-blocking.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Designs genomics experiments so technical nuisance variation (batch, lane, plate, flow cell, operator, reagent lot, processing day) is balanced against the biological variable of interest and therefore estimable rather than confounded, using constrained sample-to-batch assignment (designit, OSAT), the confounder/mediator/collider distinction, and the principle that no post-hoc correction recovers a fully confounded design. Covers detecting hidden batches with surrogate variable analysis, a decision table for downstream correction (ComBat-seq, RUVSeq, SVA) whose execution is deferred to differential-expression/batch-correction, and reproducibility metadata. Use when assigning samples to sequencing batches/lanes/plates, avoiding batch-condition confounding, deciding whether a design is salvageable by correction, choosing a correction method, or estimating the number of hidden batches. For the experimental unit, randomization, and blocking concepts see experimental-design/randomization-blocking.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Designs genomics experiments so technical nuisance variation (batch, lane, plate, flow cell, operator, reagent lot, processing day) is balanced against the biological variable of interest and therefore estimable rather than confounded, using constrained sample-to-batch assignment (designit, OSAT), the confounder/mediator/collider distinction, and the principle that no post-hoc correction recovers a fully confounded design. Covers detecting hidden batches with surrogate variable analysis, a decision table for downstream correction (ComBat-seq, RUVSeq, SVA) whose execution is deferred to differential-expression/batch-correction, and reproducibility metadata. Use when assigning samples to sequencing batches/lanes/plates, avoiding batch-condition confounding, deciding whether a design is salvageable by correction, choosing a correction method, or estimating the number of hidden batches. For the experimental unit, randomization, and blocking concepts see experimental-design/randomization-blocking.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

반복되는 수정과 주의 사항을 코드 정적 검사, 실행 중 검사, 자동화 스크립트 등의 방지 장치에 반영하여 같은 실수가 다시 발생하지 않도록 돕습니다.

• 반복되는 구현 실수를 방지합니다
• 반복 지시를 자동 검사로 바꿉니다
• 수정 내용을 메모나 규칙으로 정리합니다

Process calibrated one-dimensional NMR signals into spectra, candidate peaks, and signed integration results. Supports manual phase adjustment, baseline correction, and recorded processing settings so results can be reviewed and reproduced.

한국어 요약은 준비 중입니다. 영어 요약을 표시하고 있습니다.

• Convert raw one-dimensional NMR signals into spectra
• Check peak positions against reference signals
• Review phase and baseline corrections

Give an agent rules for consulting long-term memory before work and saving decisions, corrections, and failures afterwards. It helps carry preferences and project conventions across sessions while preserving dated history and making conflicting memories visible.

한국어 요약은 준비 중입니다. 영어 요약을 표시하고 있습니다.

• Carry preferences and project conventions across sessions
• Record user corrections for future tasks
• Preserve the history of changed decisions

Create evaluation drafts for existing skills using actual conversations and user corrections. Produce criteria and repeatable test cases, distinguish evidence from specification assumptions, and prepare an anonymized draft for human review.

한국어 요약은 준비 중입니다. 영어 요약을 표시하고 있습니다.

• Turn user corrections into repeatable test cases
• Compare promised behavior with actual usage
• Draft an evaluation from conversation history

Guide an agent through searching past decisions before work, saving new decisions with their reasons, and treating corrections as lessons. The workflow helps distinguish useful long-term knowledge from temporary details, code facts, and routine activity already captured by hooks.

한국어 요약은 준비 중입니다. 영어 요약을 표시하고 있습니다.

• Checking earlier decisions before starting a task
• Saving a resolved issue with its underlying reason
• Preserving lessons from corrections

Turns user corrections and recurring mistakes into actionable rules with confidence scores. It records when each rule applies and why it matters, so relevant lessons can be retrieved before similar work begins.

한국어 요약은 준비 중입니다. 영어 요약을 표시하고 있습니다.

• Recording a rule after a user correction
• Saving a lesson from a recurring mistake
• Keeping rules specific to one project

Turn verified corrections and repeated workflows into reusable local methods. Check existing skills first, then capture when to use a method, its steps, how to validate results, and when to stop.

한국어 요약은 준비 중입니다. 영어 요약을 표시하고 있습니다.

• Preserving a verified correction for future tasks
• Documenting a recurring workflow
• Checking for overlap with existing skills

Handle personal data access, deletion, portability, and correction requests through a structured checklist. Guide identity checks, data searches, legal exceptions, and deadlines, then draft separate acknowledgment and substantive response letters for attorney review and human delivery.

한국어 요약은 준비 중입니다. 영어 요약을 표시하고 있습니다.

• Preparing a response to a personal data access request
• Organizing checks for deletion and portability requests
• Tracking data searches across internal systems

Track how AI assistants describe a brand by comparing repeated answers to a fixed set of questions. The skill flags factual errors and changes in tone, identifies likely sources, and drafts correction requests and updates to owned content.

한국어 요약은 준비 중입니다. 영어 요약을 표시하고 있습니다.

• Monitoring AI answers after pricing or feature changes
• Checking brand descriptions during a rebrand
• Tracking answer changes after negative press

Bead-based signal normalization and cross-batch harmonization for CyTOF and high-parameter cytometry - EQ four-element bead normalization of instrument sensitivity drift (CATALYST normCytof, premessa), and reference-anchor cross-batch normalization (CytoNorm, per-cluster quantile splines). Covers the distinction between within-run drift correction and between-batch correction, the mandatory anchor/reference sample, why normalization is per-cluster with many quantiles, and the over-correction risk. Use when correcting CyTOF signal drift, harmonizing multi-batch or multi-site studies, or deciding whether to normalize data versus model batch in the design.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Corrects the gene-independent copy-number artifact in CRISPR-Cas9 screens (Aguirre 2016 / Munoz 2016 Cancer Discov) where amplified loci appear essential from DNA-damage burden of simultaneous cuts. Covers the gene-independent DNA-damage / G2-arrest mechanism, CRISPRcleanR (Iorio 2018) unsupervised pre-hoc correction, CERES (Meyers 2017) joint CN + gene-effect model, Chronos (Dempster 2021) DepMap-standard population-dynamics + CN model with lowest residual bias, the decision tree by data availability, the Spearman LFC-vs-CN diagnostic, focal-amplification examples (ERBB2 in HER2+, MYC in colorectal, FGFR1 in head and neck), and CRISPRi/a alternatives that bypass the artifact. Use when screening cancer cell lines, diagnosing essentiality at amplified loci, choosing CRISPRcleanR / CERES / Chronos, deciding whether CN correction is needed before MAGeCK / BAGEL2 / drugZ, or switching from Cas9 to CRISPRi.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Append a learning entry to AGENTS_LEARNING.md when an AI agent makes a mistake. Auto-activates after a pre-write audit auto-fix, a retrospective correction loop, or a mid-session user correction. Use when: mistake, wrong, correction, my bad, agent error, learning log.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Deep generative models for single-cell omics: probabilistic batch correction (scVI), semi-supervised annotation (scANVI), CITE-seq RNA+protein (totalVI), transfer learning (scARCHES), and DE with uncertainty. Unified setup→train→extract API on AnnData. Use harmony-batch-correction for fast linear correction without deep learning; muon for multi-modal MuData workflows.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.

Processes GDPR Article 16 right to rectification requests, covering verification of corrected data accuracy, notification to recipients under Article 19, timeline management, and completion of incomplete data. Activate for rectification, correction request, inaccurate data, Art. 16, data correction queries.

한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.