'trial' 검색 결과

Search ClinicalTrials.gov for studies by condition, drug, location, recruitment status, or phase. Retrieve trial details and eligibility criteria, summarize study information, and export results as CSV for research analysis or reviewing potential trial matches.

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• Finding recruiting trials for a specific condition and region
• Tracking trials for a drug or intervention
• Reviewing eligibility criteria and study locations

Search ClinicalTrials.gov studies by condition and recruitment status, then receive concise summaries. Use the same client to inspect API field definitions, allowed values, search areas, and field statistics, with an option to save raw responses.

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• Finding recruiting studies for a specific condition
• Getting concise summaries of clinical trial search results
• Checking API field definitions and allowed values

Research industrial AI topics such as predictive maintenance and anomaly detection. Compare papers by methods and publication venues, distinguish preprints from reviewed work, identify conflicting findings and research gaps, or build an evidence-based survey draft.

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• Researching recent predictive maintenance literature
• Comparing industrial anomaly detection methods and evaluations
• Identifying research gaps in manufacturing AI

使用 AACT (Aggregate Analysis of ClinicalTrials.gov) PostgreSQL 数据仓库进行批量、历史、聚合性临床试验数据挖掘。Use this skill when the user requests bulk SQL analysis over the full clinical trials data warehouse — historical trial trends, disease landscapes, similar-design matching, or multi-year aggregations across hundreds of thousands of NCT records. 触发场景包括：AACT 查询、临床试验批量分析、PostgreSQL 试验数据、全量 NCT 检索、试验数据挖掘、历史试验分析、clinical trials data warehouse、SQL trials、bulk trial analysis、disease landscape、试验设计相似性匹配、跨年度聚合、sponsor/phase/country 多维统计。**与 clinical-trials-v2 差异**：本 skill 走批量 SQL · 离线大数据（PostgreSQL）；v2 走实时 API · 单查询。两者互补：单条 NCT 实时状态用 v2，百万级历史挖掘用本 skill。支持云端公共 PostgreSQL（aact-db.ctti-clinicaltrials.org · 零部署）和每日 dump 本地还原（高性能 · 离线）两种连接方式，自动检测优先用本地。跨平台（macOS/Linux/Windows）参数化 SQL 防注入，read-only 强制保护。

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通过 ClinicalTrials.gov API v2 实时检索官方临床试验注册数据。触发词包括 ClinicalTrials.gov、临床试验、NCT、试验注册、招募状态、phase 1/2/3、RCT lookup、interventional trial、observational study。专注实时单次查询(≤1000 条/请求),适合"某试验最新状态/招募信息/主次要终点"场景。批量历史分析请用 aact-bulk-trials,文献检索用 pubmed-search/europepmc。

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Develop attack detection for SCADA systems that monitor and control industrial equipment. Compare network traffic and process measurements with normal behavior to identify unauthorized commands, altered sensor data, communication disruption, and indicators of known industrial malware.

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• Introducing intrusion detection in a SCADA environment
• Investigating suspected attacks on industrial control systems
• Creating detection rules for industrial protocol abuse

Query ClinicalTrials.gov via APIv2. Use when you want to search for trials by condition, drug, location, status, or phase; retrieve trial details by NCT ID; check eligibility/inclusion criteria; count trials across conditions or time periods; identify a sponsor's trial portfolio; find recruiting trials for patient matching.

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当用户询问 ClinicalTrials.gov / 临床试验 / NCT / 试验注册 / 招募状态 / phase 1/2/3 / RCT lookup / sponsor 检索 / interventional trial / observational study / 主次要终点 / trial outcomes / 试验招募中 / recruiting status 时,通过 ClinicalTrials.gov API v2 实时检索官方注册数据。专注实时单次查询(≤1000 条/请求),典型场景: "某 NCT 试验最新状态"、"BTK 抑制剂 Phase 3 在招募试验"、"某试验已发布的主次要终点结果"。明确边界: 批量 >10k 试验 / 全库 SQL 历史分析 → aact-bulk-trials; 关联 PubMed 文献 → pubmed-eutils; RCT 自动 GRADE 评级 → medical-evidence-grading; 引用入报告附录 → evidence-appendix-sync。跨平台无锁(Claude Code / Codex / Cursor 通用)。

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Review account registration and free trial signup flows to find obstacles in fields, authentication, and error messages. Get prioritized recommendations and test ideas to reduce abandonment and help more people complete registration.

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• Investigating where users abandon registration
• Reducing required signup fields
• Improving mobile signup forms

Assess industrial control systems by mapping devices, network zones, and exposed protocols. The workflow prioritizes observing traffic and read-only checks, then organizes evidence about configuration weaknesses, firmware vulnerabilities, and potential effects on physical processes.

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• Map industrial devices and network zones
• Inspect captured industrial protocol traffic
• Review control system configurations offline

Build a structured research dossier for a defined patient population, covering epidemiology, disease biology, current treatment, regulatory precedents, and major clinical trials. Receive a cited report and structured data to inform therapeutic development and trial planning.

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• Characterizing a target patient population
• Reviewing current treatments and unmet needs
• Researching regulatory precedents and landmark trials

Designs Bayesian clinical trials including Phase I dose-finding (BOIN, CRM, EWOC, mTPI-2), meta-analytic-predictive (MAP) priors with robust mixtures for external data borrowing, EXNEX for basket trials, hierarchical models for safety AE (Berry-Berry), Bayesian platform trials (I-SPY 2, GBM AGILE, REMAP-CAP), and posterior probability stopping rules. Covers FDA Bayesian Devices Guidance (2010), FDA Bayesian Methodology in Drugs Draft (January 2026), BOIN Fit-for-Purpose qualification (December 2021), and Project Optimus dose-optimisation. Use when designing dose-finding studies, platform trials, or sensitivity analyses with informative priors.

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Build industrial-grade SCADA/HMI dashboards in MATLAB following industrial-HMI conventions (ISA-101-aligned): gray-field philosophy, alarms at source, write safeguards, fixed-range trends, drill-down layout. Produces a real App Designer app (.mlapp, or plain-text .m+.xml on R2026b+) by handing serialization to the matlab-build-app skill when available, and falls back to a programmatic .m app otherwise. Use when wrapping OPC UA / Modbus / MQTT / OSI PI / PI AF monitoring scripts into a live operator app, building plant overviews, designing operator dashboards, or any time a user asks for a "SCADA dashboard", "HMI", "plant dashboard", "operator screen", or "industrial monitoring app" in MATLAB. Trigger on: SCADA, HMI, industrial dashboard, plant overview, operator screen, uigauge, uilamp, alarm banner, gray-field, ISA-101, OPC UA dashboard, setpoint, write safeguards, alarm visualization, OSIsoft PI, AVEVA PI, PI Server, PI Data Archive, PI AF, PI Asset Framework, piclient, afclient.

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Designs Bayesian clinical trials including Phase I dose-finding (BOIN, CRM, EWOC, mTPI-2), meta-analytic-predictive (MAP) priors with robust mixtures for external data borrowing, EXNEX for basket trials, hierarchical models for safety AE (Berry-Berry), Bayesian platform trials (I-SPY 2, GBM AGILE, REMAP-CAP), and posterior probability stopping rules. Covers FDA Bayesian Devices Guidance (2010), FDA Bayesian Methodology in Drugs Draft (January 2026), BOIN Fit-for-Purpose qualification (December 2021), and Project Optimus dose-optimisation. Use when designing dose-finding studies, platform trials, or sensitivity analyses with informative priors.

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Search the ClinicalTrials.gov registry through its version 2 REST API for interventional and observational studies, their phases, enrolment, endpoints, sponsors, and posted results. Use this skill to survey who is developing what against an indication, date a competitor's programme, read primary and secondary outcome measures, find eligibility criteria, and distinguish a study that completed from one that was terminated or withdrawn. Also trigger on ClinicalTrials.gov, NCT number, trial registry, study phase, enrolment, primary outcome measure, recruiting status, trial sponsor, or competitive landscape.

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Designs Bayesian clinical trials including Phase I dose-finding (BOIN, CRM, EWOC, mTPI-2), meta-analytic-predictive (MAP) priors with robust mixtures for external data borrowing, EXNEX for basket trials, hierarchical models for safety AE (Berry-Berry), Bayesian platform trials (I-SPY 2, GBM AGILE, REMAP-CAP), and posterior probability stopping rules. Covers FDA Bayesian Devices Guidance (2010), FDA Bayesian Methodology in Drugs Draft (January 2026), BOIN Fit-for-Purpose qualification (December 2021), and Project Optimus dose-optimisation. Use when designing dose-finding studies, platform trials, or sensitivity analyses with informative priors.

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Expert-level industrial automation covering PLCs, SCADA, industrial networks, safety systems, robot integration, and Industry 4.0 technologies.

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Designs Bayesian clinical trials including Phase I dose-finding (BOIN, CRM, EWOC, mTPI-2), meta-analytic-predictive (MAP) priors with robust mixtures for external data borrowing, EXNEX for basket trials, hierarchical models for safety AE (Berry-Berry), Bayesian platform trials (I-SPY 2, GBM AGILE, REMAP-CAP), and posterior probability stopping rules. Covers FDA Bayesian Devices Guidance (2010), FDA Bayesian Methodology in Drugs Draft (January 2026), BOIN Fit-for-Purpose qualification (December 2021), and Project Optimus dose-optimisation. Use when designing dose-finding studies, platform trials, or sensitivity analyses with informative priors.

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Designs Bayesian clinical trials including Phase I dose-finding (BOIN, CRM, EWOC, mTPI-2), meta-analytic-predictive (MAP) priors with robust mixtures for external data borrowing, EXNEX for basket trials, hierarchical models for safety AE (Berry-Berry), Bayesian platform trials (I-SPY 2, GBM AGILE, REMAP-CAP), and posterior probability stopping rules. Covers FDA Bayesian Devices Guidance (2010), FDA Bayesian Methodology in Drugs Draft (January 2026), BOIN Fit-for-Purpose qualification (December 2021), and Project Optimus dose-optimisation. Use when designing dose-finding studies, platform trials, or sensitivity analyses with informative priors.

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Designs Bayesian clinical trials including Phase I dose-finding (BOIN, CRM, EWOC, mTPI-2), meta-analytic-predictive (MAP) priors with robust mixtures for external data borrowing, EXNEX for basket trials, hierarchical models for safety AE (Berry-Berry), Bayesian platform trials (I-SPY 2, GBM AGILE, REMAP-CAP), and posterior probability stopping rules. Covers FDA Bayesian Devices Guidance (2010), FDA Bayesian Methodology in Drugs Draft (January 2026), BOIN Fit-for-Purpose qualification (December 2021), and Project Optimus dose-optimisation. Use when designing dose-finding studies, platform trials, or sensitivity analyses with informative priors.

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Design and improve in-app screens that invite users to pay or upgrade. Plan messages, timing, feature previews, and payment steps for usage limits, locked features, and trial endings, with clear options to dismiss or continue free.

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• Design upgrade prompts at free usage limits
• Improve trial expiration screens
• Explain paid features when users try to access them

Design monitoring for industrial attacks that alter controller programs while hiding changes with false sensor readings. Compare PLC program blocks against known-good copies and check physical measurements against process models to identify suspicious inconsistencies.

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• Monitoring industrial controller programs for unauthorized changes
• Investigating discrepancies between sensor readings and equipment behavior
• Planning detection across IT and industrial control systems

Build normal traffic profiles for industrial control networks and identify unusual connections, polling intervals, and protocol operations. Use machine learning and process records to investigate deviations and produce anomaly reports with severity levels.

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• Establishing normal traffic profiles for industrial networks
• Detecting unusual connections and polling intervals
• Investigating Nozomi Guardian or Dragos alerts

Review signup and trial registration flows to identify obstacles to completion. The skill produces prioritized recommendations for fields, authentication, wording, and layout, plus measurement plans and A/B test ideas for checking proposed improvements.

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• Investigating signup drop-off
• Reviewing required registration fields
• Improving mobile signup usability