Expert-level genetics covering Mendelian inheritance, molecular genetics, mutations, linkage analysis, population genetics, epigenetics, and GWAS. Covers classical and modern approaches from Mendel to CRISPR.
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실행 점수 미검증
설치 방법 보기설치하기 전에 에이전트에게 전달되는 지시 내용을 확인할 수 있습니다.
Law of Segregation: alleles separate during gamete formation. Law of Independent Assortment: genes on different chromosomes assort independently. Dominance patterns: complete, incomplete, codominance. Epistasis: gene interaction modifying phenotypic ratios. Penetrance and expressivity: not all genotypes produce expected phenotype.
DNA replication: semi-conservative, leading/lagging strand synthesis. Transcription: promoters, enhancers, RNA polymerase, splicing. Translation: codons, tRNA, ribosome, start/stop signals. Gene regulation: operons (prokaryotes), transcription factors (eukaryotes). Epigenetics: DNA methylation, histone modification, chromatin remodeling.
Point mutations: missense, nonsense, silent, frameshift. Chromosomal mutations: deletion, duplication, inversion, translocation. DNA repair mechanisms: BER, NER, MMR, DSBR. Mutagens: chemical, radiation, biological.
Genetic linkage: genes on same chromosome tend to inherit together. Recombination frequency: measure of map distance in centimorgans. Genetic maps vs physical maps. LOD score analysis for linkage detection.
Hardy-Weinberg equilibrium: p2 + 2pq + q2 = 1. Deviations: mutation, selection, drift, migration, non-random mating. Genetic drift: founder effect, bottleneck effect. Natural selection: directional, stabilizing, disruptive.
Genome-wide association studies: SNPs, Manhattan plots, p-value thresholds. Polygenic traits: multiple loci each with small effect. Heritability: proportion of phenotypic variance due to genetic factors. Linkage disequilibrium: non-random association of alleles at nearby loci.
| Pitfall | Fix |
|---|---|
| Confusing penetrance with expressivity | Penetrance is all-or-nothing, expressivity is degree |
| Ignoring epistasis | Check for modified ratios in dihybrid crosses |
| Applying H-W to non-equilibrium populations | Verify all 5 conditions first |
| Confusing cM with physical distance | Recombination frequency is not linear at large distances |
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Expert-level abstract algebra knowledge. Use when working with groups, rings, fields, modules, Galois theory, representation theory, or algebraic structures. Also use when the user mentions 'group', 'ring', 'field', 'homomorphism', 'isomorphism', 'normal subgroup', 'quotient group', 'Sylow theorem', 'Galois theory', 'polynomial ring', 'ideal', 'module', 'vector space', or 'representation theory'.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
Expert-level acoustics knowledge. Use when working with sound waves, acoustic propagation, resonance, standing waves, Doppler effect, room acoustics, ultrasound, noise control, musical acoustics, or architectural acoustics. Also use when the user mentions 'sound wave', 'decibel', 'frequency', 'resonance', 'standing wave', 'Doppler effect', 'acoustic impedance', 'reverberation', 'ultrasound', 'noise control', 'harmonics', or 'sound intensity'.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.
Expert-level aerodynamics covering subsonic and supersonic flow, lift and drag, airfoil theory, boundary layers, compressible flow, and CFD methods.
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Expert-level air quality engineering covering pollutant sources, atmospheric dispersion, air quality standards, emission controls, and air quality modeling.
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Expert-level aircraft structures covering structural design philosophy, wing and fuselage analysis, fatigue and damage tolerance, composite structures, and certification.
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Expert-level algorithms and complexity theory covering sorting, searching, graph algorithms, dynamic programming, greedy algorithms, NP-completeness, and algorithm design paradigms.
한국어 요약은 준비 중입니다. 원문 설명을 표시하고 있습니다.