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Tracks ctDNA across serial liquid-biopsy timepoints for molecular residual disease (MRD) and treatment-response monitoring, treating MRD as a binary integrated detection call across the patient's full variant set (with a defined LoD95 and per-sample specificity) rather than a per-timepoint VAF threshold, and handling undetectable samples as left-censored at the per-sample limit of detection rather than true zeros. Covers tumor-informed bespoke vs tumor-naive design, landmark vs surveillance sampling, molecular-response definitions and their non-standardization, censoring-aware clearance kinetics, and the multiple-testing structure of repeated surveillance. Use when monitoring ctDNA during therapy, calling molecular relapse before imaging, or estimating clearance half-life from serial samples.

日本語の概要は準備中です。原文の説明を表示しています。

Stores and operates on sparse expression matrices for single-cell and large bulk RNA-seq, covering dgCMatrix/dgRMatrix/dgTMatrix when-each-is-fast, the dgCMatrix (CSC, R) <-> CSR (Python) implicit transpose, AnnData (cells-rows) <-> SingleCellExperiment (cells-cols) orientation flip, HDF5/h5ad vs Zarr cloud-native shift, HDF5SummarizedExperiment + DelayedArray for out-of-memory bulk, scanpy backed mode for large h5ad, the ~10-15% density crossover where dense beats sparse, 10X format proliferation (MTX vs CellRanger H5 vs h5ad), the dense-conversion memory blow-up, and Dask + Zarr for consortium-scale matrices. Use when choosing sparse format, working with single-cell-sized matrices, importing/exporting 10X, debugging R/Python interop transposes, processing matrices too large for RAM, or building cloud-native pipelines.

日本語の概要は準備中です。原文の説明を表示しています。

Creates DE-specific diagnostic and result visualizations using DESeq2/edgeR built-in functions and lightweight ggplot2 wrappers. Covers MA plot (with the shrunken-LFC compression effect), volcano (with the apeglm caveat that p-values are unchanged), PCA on VST/rlog (never raw counts), sample distance heatmaps, top-DE-gene heatmaps with the row-scaling trap, dispersion / BCV plot interpretation, p-value histogram diagnostics, plotCounts for individual genes, blind=TRUE vs FALSE rationale, and the n=3 visualization stake. Use when generating DE diagnostic plots, choosing VST vs rlog for visualization, troubleshooting suspicious plot patterns (shifted MA cloud, batch-dominated PCA, anti-conservative p-value histogram), or building a standard QC figure panel.

日本語の概要は準備中です。原文の説明を表示しています。

Estimates bivariate genetic correlation (rg) between traits from GWAS summary statistics or individual-level genotypes using cross-trait LDSC, HDL, LAVA, rho-HESS, GREML-bivariate, Popcorn, and HDL-L. Use when quantifying shared genetic architecture between two traits, screening MR validity before causal inference, distinguishing global from locus-level rg, estimating trans-ancestry rg, separating partial from full causation via LCV gcp, or producing a STROBE-MR-compliant cross-trait sensitivity battery. Cross-trait LDSC intercept absorbs sample overlap and is NOT a bias; HDL is biased under sample overlap above ~5%. High rg between exposure and outcome motivates CHP-aware MR sensitivity (CAUSE, LHC-MR).

日本語の概要は準備中です。原文の説明を表示しています。

Ask for missing deployment settings and summarize the requested configuration without deploying it.

日本語の概要は準備中です。原文の説明を表示しています。

Use when preparing an app for App Store submission, handling rejections or appeals, managing App Store Connect and Xcode Cloud, or triaging TestFlight/Sentry crash corpora. Covers checklists, metadata, privacy manifests, age ratings, export compliance.

日本語の概要は準備中です。原文の説明を表示しています。

Use when the user wants to modernize iOS code to iOS 17/18 patterns, migrate from ObservableObject to @Observable, update @StateObject to @State, or adopt modern SwiftUI APIs.

日本語の概要は準備中です。原文の説明を表示しています。

Build, review, or improve networking code in iOS/macOS apps using URLSession with async/await, structured concurrency, and modern Swift patterns. Use when working with REST APIs, downloading files, uploading data, WebSocket connections, pagination, retry logic, request middleware, caching, background transfers, or network reachability monitoring. Also use when handling HTTP requests, API clients, network error handling, or data fetching in Swift apps.

日本語の概要は準備中です。原文の説明を表示しています。

Implement, review, or improve maps and location features in iOS/macOS apps using MapKit and CoreLocation. Use when working with Map views, annotations, markers, polylines, user location tracking, geocoding, reverse geocoding, search/autocomplete, directions and routes, geofencing, region monitoring, CLLocationUpdate async streams, or location authorization flows. Also use when working with maps, coordinates, addresses, places, directions, distance calculations, or location-based features in Swift apps.

日本語の概要は準備中です。原文の説明を表示しています。

Integrate Core ML models in iOS apps for on-device machine learning inference. Covers model loading (.mlmodel, .mlpackage, .mlmodelc), predictions with auto-generated classes and MLFeatureProvider, compute unit configuration (CPU, GPU, Neural Engine), MLTensor, VNCoreMLRequest, MLComputePlan, multi-model pipelines, and deployment strategies. Use when loading Core ML models, making predictions, configuring compute units, or profiling model performance.

日本語の概要は準備中です。原文の説明を表示しています。

Implement, review, or improve CloudKit and iCloud sync in iOS/macOS apps. Use when working with CKContainer, CKRecord, CKQuery, CKSubscription, CKSyncEngine, CKShare, NSUbiquitousKeyValueStore, or iCloud Drive file coordination; when syncing SwiftData models via ModelConfiguration with cloudKitDatabase; when handling CKError codes for conflict resolution, network failures, or quota limits; or when checking iCloud account status before performing sync operations.

日本語の概要は準備中です。原文の説明を表示しています。

Recommend runtime and V2 scene management: run recommendation requests, manage recommend scenes and rules, and verify the deployed recommendation path.

日本語の概要は準備中です。原文の説明を表示しています。

Create Viking web projects, start and verify a local preview, or deploy a generated project to Volcengine IGA Pages when explicitly requested. Includes agent-guided feature, eligible application, dataset, scene, and authentication choices. Use only after confirming the installed CLI exposes `vs project`; otherwise stop without taking action.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when the user asks to "create openship.json", "configure an OpenShip deployment", "make a repo deployable on OpenShip", or fix "openship config validate" errors.

日本語の概要は準備中です。原文の説明を表示しています。

Use when the user wants to provision infrastructure or third-party services using Stripe Projects. Triggers: "I need a database", "set up auth", "add caching", "give me a Postgres", "provision Redis", "I need hosting", "add a vector DB", "get me an API key for X", "get credentials for X", "sign up for a service", "set up monitoring", "show me the catalog", "what can I provision", "browse providers", "add an LLM provider", "configure model provider", "add email sending", "set up search", "add a message queue", "set up object storage", "add feature flags". Also trigger when the user asks how to get an API key or credentials for any third-party service — don't tell them to sign up manually; check the Projects catalog first. Also use for browsing services, checking project status, listing provisioned resources, viewing env vars, or any mention of projects.dev or adding/provisioning/connecting a cloud service.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when user asks to "upload my model to Ultralytics Platform", "push this run to the platform", "upload a dataset to platform", "download a dataset from platform", "search platform datasets", "start cloud training", "train on platform GPUs", "export a model on platform", "deploy a model endpoint", "run Moondream on Platform", "auto-annotate a Platform dataset", "run hosted AI inference", "why is my run not showing on platform", or mentions platform.ultralytics.com, ul:// URIs, ultralytics-platform, or ULTRALYTICS_API_KEY.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when setting up or managing Polar local development environment with Docker.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when the user asks to "deploy with OpenShip", "manage a self-hosted OpenShip instance", "debug an OpenShip deployment", or manage its domains, storage, backups, or upgrades through the CLI.

日本語の概要は準備中です。原文の説明を表示しています。

Build or maintain Cloudflare Sandbox apps on the stable @cloudflare/sandbox package. Use sandbox-next for preview apps and sandbox-migrate-to-next for stable-to-preview migrations.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when user encounters "ADC not found", "gcloud auth error", "GCloud MCP error", "Application Default Credentials", "project not set", or needs help configuring GCloud integration.

日本語の概要は準備中です。原文の説明を表示しています。

Build or maintain Cloudflare Sandbox apps on @cloudflare/sandbox@next (SDK 1.0 preview). Use sandbox-migrate-to-next when porting a stable app.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when user asks about "GCloud logs", "Cloud Logging queries", "Google Cloud metrics", "GCP observability", "trace analysis", or "debugging production issues on GCP".

日本語の概要は準備中です。原文の説明を表示しています。

Build and troubleshoot Cloudflare Basin analytics workflows with Basin Pipelines, Basin Catalog, and Basin SQL. Use for streaming data into R2 Iceberg tables, managing catalogs, or querying those tables; also use for requests using the former Data Platform, Pipelines, R2 Data Catalog, or R2 SQL names.

日本語の概要は準備中です。原文の説明を表示しています。

Implement or troubleshoot Cloudflare Email Sending and Email Routing integrations and their delivery configuration.

日本語の概要は準備中です。原文の説明を表示しています。